Difference between revisions of "Phosphatase Family NagD"
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[[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HAD|Fold HAD]]: [[Phosphatase_Superfamily_HAD|Superfamily HAD]]: [[Phosphatase_Family_NagD|Family NagD]] | [[Phosphatase classification|Phosphatase Classification]]: [[Phosphatase_Fold_HAD|Fold HAD]]: [[Phosphatase_Superfamily_HAD|Superfamily HAD]]: [[Phosphatase_Family_NagD|Family NagD]] | ||
| − | The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies | + | The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies: |
| − | * [[Phosphatase_Subfamily_PGP|PGP]] | + | * [[Phosphatase_Subfamily_PGP|PGP]] is ubiquitous in eukaryotes. The two members in human have distinct functions: PGP is a putative tyrosine-specific protein phosphatase, and PDXP (chronophin) dephosphorylates cofilin on serine, and also dephosphorylates pyridoxal 5'-phosphate. PDXP is mainly expressed in brain; PGP is widely expressed in different tissues. |
| − | * [[Phosphatase_Subfamily_LHPP|LHPP]] is a protein histidine phosphatase subfamily conserved in | + | * [[Phosphatase_Subfamily_LHPP|LHPP]] is a protein histidine phosphatase subfamily conserved in holozoa. |
| − | * [[Phosphatase_Subfamily_CUT|CUT]] - | + | * [[Phosphatase_Subfamily_CUT|CUT]] is a mitochondrial-associated probable non-protein phosphatase. |
Latest revision as of 20:15, 21 March 2015
Phosphatase Classification: Fold HAD: Superfamily HAD: Family NagD
The NagD family of HAD-fold phosphatases has three eukaryotic subfamilies:
- PGP is ubiquitous in eukaryotes. The two members in human have distinct functions: PGP is a putative tyrosine-specific protein phosphatase, and PDXP (chronophin) dephosphorylates cofilin on serine, and also dephosphorylates pyridoxal 5'-phosphate. PDXP is mainly expressed in brain; PGP is widely expressed in different tissues.
- LHPP is a protein histidine phosphatase subfamily conserved in holozoa.
- CUT is a mitochondrial-associated probable non-protein phosphatase.
