Difference between revisions of "Phosphatase Family HP2"
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====== [[Phosphatase_Subfamily_ACP2|ACP2]] ====== | ====== [[Phosphatase_Subfamily_ACP2|ACP2]] ====== | ||
ACP2 is a phosphatase subfamily that usually has multiple copies per genome. Human has three copies with different tissue specificity. It is found in holozoa, ameobozoa, and some protists. | ACP2 is a phosphatase subfamily that usually has multiple copies per genome. Human has three copies with different tissue specificity. It is found in holozoa, ameobozoa, and some protists. | ||
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| + | ====== [[Phosphatase_Subfamily_MINPP1|MINPP1]] ====== | ||
| + | MINPP1 is a non-protein phosphatase found in a broad of eukaryotes, including most metazoan and amoebazoan. | ||
====== [[Phosphatase_Subfamily_PXYLP1|PXYLP1]] (ACPL2) ====== | ====== [[Phosphatase_Subfamily_PXYLP1|PXYLP1]] (ACPL2) ====== | ||
Revision as of 00:21, 2 January 2015
Phosphatase Classification: Fold HP: Superfamily HP (histidine phosphatase): Family HP, branch 2
Refer to Pfam ID PF00328 for general information.
Contents
Subfamilies
ACP2
ACP2 is a phosphatase subfamily that usually has multiple copies per genome. Human has three copies with different tissue specificity. It is found in holozoa, ameobozoa, and some protists.
MINPP1
MINPP1 is a non-protein phosphatase found in a broad of eukaryotes, including most metazoan and amoebazoan.
PXYLP1 (ACPL2)
PXYLP1 dephosphorylates xylose, a sugar, in the glycosaminoglycan-protein linkage region of proteoglycans [1]. It is widely found in bilateria.
References
- Koike T, Izumikawa T, Sato B, and Kitagawa H. Identification of phosphatase that dephosphorylates xylose in the glycosaminoglycan-protein linkage region of proteoglycans. J Biol Chem. 2014 Mar 7;289(10):6695-6708. DOI:10.1074/jbc.M113.520536 |
- Zhang XQ, Lee MS, Zelivianski S, and Lin MF. Characterization of a prostate-specific tyrosine phosphatase by mutagenesis and expression in human prostate cancer cells. J Biol Chem. 2001 Jan 26;276(4):2544-50. DOI:10.1074/jbc.M006661200 |
- Meng TC and Lin MF. Tyrosine phosphorylation of c-ErbB-2 is regulated by the cellular form of prostatic acid phosphatase in human prostate cancer cells. J Biol Chem. 1998 Aug 21;273(34):22096-104. DOI:10.1074/jbc.273.34.22096 |
