Phosphatase Subfamily PTPRB

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Phosphatase Classification: Fold CC1: Superfamily CC1: Family PTP: Subfamily PTPRB


PTPRC (CD45) is a vertebrate-specific receptor PTP involved in immune signaling.

Evolution

PTPRB subfamily is found across metazoan. It has multiple copies per genomes in bilateral.

Domain Structure

Functions

(summary)

PTPRB (VE-PTP)

PTPRB is glycosylated (phosphacan).

PTPRB interacts with neuronal receptors and promotes neurite outgrowth [1].

References

Error fetching PMID 12700241:
  1. Error fetching PMID 12700241: [Garwood03]
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