Gene mkpB-2 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP1
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP011_AA protein Get Run
DdisP011_AA_207-352 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Rhodanese Rhodanese-like domain 30-65 5.2e-08 25.4 Pfam-A 7-49 (113) alignment
Range on Protein: 30-65
Range on HMM: 7-49/113.0
QDI-GSSKIIIDLRTKEQYEKNHIRTSVNIPP------PPSTT
. . ... ...| |..|.|.| ||. .||.|.       ....
ellekekvvllDvRspeeyakghIpgAvnvpldslyprrdlff

0044763 (Phosphotyrosine protein) phosphatases II 204-349 5.1e-40 132.3 In-house 18-171 (178) alignment
Range on Protein: 204-349
Range on HMM: 18-171/178.0
GSQLYPSEIIkDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHL---------YKYYRANLDDRPKANIYEHFEPVIQFINDCK-KQGGRVLIH
. ....|||. ..||||.. .| ....| .|.|||.||...||   ....         ..|.. ...| .  ...|||. ...||...  ..||.||.|
sdyinaseil.pglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVH

CAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRScINPNFGFVKQLKDYQQHLT
| .|..||.|.|.|||||. .... .|. . ...|. |.||.|...||......| 
CsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrll

subfamily_DSP1_pd Subfamily DSP1 205-355 1.4e-67 220.9 In-house 12-163 (163) alignment
Range on Protein: 205-355
Range on HMM: 12-163/163.0
SQLY-PSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTT
..|| |.|.|.||||||....|.|...| .|.||...|...|||.|...|..|....|.|.|||.|...||.||.||...||..|.|||||..|||||.|
lklydPvekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsst

VVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTLEWEKQ
..||||||........||.|.||.||.|.||.|||.||..|...|.||.||.
lclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkllleleka

0045098 (Phosphotyrosine protein) phosphatases II 205-351 7.2e-29 96.5 In-house 18-274 (278) alignment
Range on Protein: 205-351
Range on HMM: 18-274/278.0
SQLYPSEiIKDFLYLGGAE-----------------------------------------NAGNRQQLINLKITHLVNMAGELDD---------------
.. .||| | ..||||...                                          | . ..| .|.||..|........               
llgipse.itpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggsl

-------------------------------------VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKK--------------QGGRVLIHCAMG
                                      . . ..|.     . |  .|. .|  ...||... |              .||.||.|| .|
tygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaG

ISRSTTVVLAYLMKED---HMTYSDAFTFCKQKRSC-INPNFGFVKQLKDYQQHLTLE
..|. |.|.||||.|    .... .|... ...| . . .|... ..| .....| | 
vgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelllr

subfamily_Slingshot_pd Subfamily Slingshot 206-358 3.2e-42 137.8 In-house 15-167 (169) alignment
Range on Protein: 206-358
Range on HMM: 15-167/169.0
QLYPSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVV
||  .  | |..|||   || | ..| . ......|.. |.|. .|. ..|.. .. | ..........   .||. .||.| .||.|| ||.|||...|
qldsaskifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastv

LAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTLEWEKQEKL
.|| ||| .... .|... |..||.|.|| ||.|||. |.  |. . ....||
iayamkeyglsleealeyvkerrsvikPnkgflkqleeyeGileaskqrhnkl

subfamily_MKPLT_pd Subfamily MKPLT 206-346 1.1e-40 132.8 In-house 18-158 (164) alignment
Range on Protein: 206-346
Range on HMM: 18-158/164.0
QLYPSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVV
. ||| ...| |||| |..| |.. | .||||| ||.. |  | .|.  .| . ...| .. .. ...| . .|. |  . |||||.|| .| |||..| 
kiypsvvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvt

LAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
.|.|.|    |. .|. . |..||...|| ||.|||  ...
vafLikskgwtlkeayeylkerrsivapnrGflkqlakfee

subfamily_MKPLV_pd Subfamily MKPLV 206-346 1.1e-40 132.8 In-house 18-158 (164) alignment
Range on Protein: 206-346
Range on HMM: 18-158/164.0
QLYPSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVV
. ||| ...| |||| |..| |.. | .||||| ||.. |  | .|.  .| . ...| .. .. ...| . .|. |  . |||||.|| .| |||..| 
kiypsvvledtlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvt

LAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
.|.|.|    |. .|. . |..||...|| ||.|||  ...
vafLikskgwtlkeayeylkerrsivapnrGflkqlakfee

subfamily_DSP6_pd Subfamily DSP6 207-350 8.6e-41 133.1 In-house 12-156 (158) alignment
Range on Protein: 207-350
Range on HMM: 12-156/158.0
LYPSEIIKdFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLY--KYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTV
 .| ||.. .|||| |..| |.. | .||| ...|.. .|.... .    ||..  ..|. ..|. ..|   |.||.. ...   ||.||  ||||| ||
efpveilp.llylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtv

VLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTL
.||||||. ...  ||. . |...| | ||| |..||.|....|.|
tlaylmkklalslndaydlvkkrksnisPnfnfmgqlldferslrl

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 207-346 1.7e-36 119.0 In-house 5-145 (148) alignment
Range on Protein: 207-346
Range on HMM: 5-145/148.0
LYPSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHL-YKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVV
 .|||| . ||.||  . | . ..| .| .|..||.. | | .. .   .|.  .||| || ..   ||..|.|..  |..|.|||.|. ||.|||. ..
tfpseikdafLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssala

LAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
|..|.. ....  .|. . |.||  ..|| ||.||| ...|
llwlidfkrvslkealalvkskrryvdpnlgfLkqLaeleq

subfamily_STYXL1_pd Subfamily STYXL1 207-348 3.6e-31 101.5 In-house 9-153 (157) alignment
Range on Protein: 207-348
Range on HMM: 9-153/157.0
LYPSEIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPH---LYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTT
 ||.|.. ..||||  ..| |..   .||.   ||.. . |...       |  . ...| ..|.. |... ..|||.. ||.|  ||.    |||||..
tyPvevlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaa

VVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
|..|||| . ..|. .|... |. .. ..|| .||.||......|
viiaylmyskkitlkkaykylkkCkenvkPnrafveqlseWekql

subfamily_LRR-DSP_pd Subfamily LRR-DSP 208-349 1.5e-42 139.5 In-house 119-259 (263) alignment
Range on Protein: 208-349
Range on HMM: 119-259/263.0
YPSEIIKDfLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRA-NLDDRPKANIYEHFEPVIQFINDCKKQGGrVLIHCAMGISRSTTVVL
 |.|||.. |.||| . | |.  | .| .||..   .... ..|.|.||.   ...| ..|.|. ||| .  ||.. .|.|| ||.||  |.|||.|.|.
vPdeiidk.lflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvi

AYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLT
.|||| ..... .|. . ..||. |.|| ||..||| |...| 
sylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklf

0048076 (Phosphotyrosine protein) phosphatases II 208-348 5.2e-38 125.3 In-house 3-142 (145) alignment
Range on Protein: 208-348
Range on HMM: 3-142/145.0
YPSEIIKDfLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLA
.||||. . ||||.  .| ....| .|.||...|.. ||...... ..|.. ...|..  ...|... ...||... |.||.||.|| .|..|..|.|.|
wpseilpg.lylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaa

YLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
|||.. .... .|. . ...|....||.|....|......|
ylmlllgvsleealelvrsqrpgavpnpgqlrflyefelel

0051429 (Phosphotyrosine protein) phosphatases II 208-350 9.3e-20 66.8 In-house 15-226 (272) alignment
Range on Protein: 208-350
Range on HMM: 15-226/272.0
YPSEIIKDFLYLGGAE---NAGNRQQLINLKITHLVNMAGEL------DDVYPHLYKYYRANLDDRPKANIYEHF-------------------------
| .......||..|.    .| . ..| .|.|.. |.. .|        | |..  .|.. .. |.    |  ..                         
ygrvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlll

-----------------------EPVIQFINDCKKqGGRVLIHCAMGISRSTTVVLAYLMKeDHMT--------------YSDAFTFCKQKRSCINPNFG
                       |....... . . ||.||.||. |..|. |||...|.    ..              . .|    ...| ..... .
sagearevmhlhytdwpdhgvpqeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqtee

FVKQLKDYQQHLTL
....| .. ..|  
qylflyeallellr

PTPc_motif_SM00404 209-346 1.1e-40 133.7 In-house 2-139 (140) alignment
Range on Protein: 209-346
Range on HMM: 2-139/140.0
PSEIIKDfLYLGGAENAGNRQQLINLKITHLVNMAGELDD-VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLA
||.| .. ||||....| |...| .|.||| .|.. | .       ... . .|||  |... .... |..||....|.||.||.||..|.||| |...|
psrilph.lylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliia

YLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
|||.........|. | |..|..|.||..||.|| .|..
YlmryrqlslaeayefvkerRpiispnlnfvrqLieyek

0048179 (Phosphotyrosine protein) phosphatases II 209-348 3.1e-36 119.6 In-house 4-144 (144) alignment
Range on Protein: 209-348
Range on HMM: 4-144/144.0
PSEIIkDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLY--KYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVL
||||. . ||||.   | . ..| .|.||...|.. | .  ..  .  .|.. ...|..  ...|... ...||... ..||.||.|| .|..|..|.|.
pseil.pglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlva

AYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
|||||. .... .|. . ...|....||.|....|..|...|
aylmkklglsleealalvrsrrpgavpnpgqlrfLleyekll

PTEN_1 209-348 4.6e-31 103.1 In-house 36-191 (196) alignment
Range on Protein: 209-348
Range on HMM: 36-191/196.0
PSE----IIKDFLYLGGAENA-GNRQQLINLKITHLVNMAGELDD---------VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKK--QGGRVLI
||.     | ..||.| .. .  ....|   .||..||.. | ..          . . ..|..   .| .. .. |.|. . .||. ...  .|. ||.
psrpllqeideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlV

HCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
||. |..|| ||| ||||.   .|. .|. . ..||....|| .. ..|. |.. |
HCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfael

0041856 (Phosphotyrosine protein) phosphatases II 210-348 4.3e-31 103.3 In-house 19-172 (182) alignment
Range on Protein: 210-348
Range on HMM: 19-172/182.0
SEIIKDFLYLGGAEN--------------AGNRQQLINLKITHLVNMAGEL---DDVYPHLYKYYRANLDDRPKANiyehFEPVIQFINDCKKQGGRVLI
.  | . ||||.  .              | . ..| .|.||..||...||   .... . ..|.. . .| .  .    .. ...||......||.||.
ldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvlV

HCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRS--CINPNFGFVKQLKDYQQHL
|| .|..|. |.|.|||||. .... .|. . ...|.  .|.||..|. ||. .. .|
HCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallelll

subfamily_DSP10_pd Subfamily DSP10 211-349 3.5e-39 128.2 In-house 15-154 (159) alignment
Range on Protein: 211-349
Range on HMM: 15-154/159.0
EIIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPH-LYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYL
  .  ||.|| ...| . . | .|.||...|.. ..   . .   || | .. |  | |. ..||  ..||.. .|.| |||.||  |||||.|||.|||
sqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYl

MKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLT
||. ... .||. | |.||. | ||..|. ||... ..|.
mkhlnlslndaykfvkekrpiisPnLnfmGqLlefekeln

subfamily_DSP15_pd Subfamily DSP15 211-355 1e-38 126.8 In-house 4-146 (151) alignment
Range on Protein: 211-355
Range on HMM: 4-146/151.0
EIIKDfLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHlYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLM
..... ||||. ... ....| . .|||....  .   . ..  .|   ...| |.|.. ..|.  ..|| .|. ... ||.||..|.|||.|.| ||||
kvlpg.lylgnfrdskdeelLkeknithilsvhdnakkllkd.ieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlm

KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTLEWEKQ
   .. . ||... |..||. |||||| .|||.|... . |..||
tvtelnwrdalevikaaRsvanPnfGfkrqlkeyektklkeyrkq

0046846 (Phosphotyrosine protein) phosphatases II 211-348 1.8e-28 94.9 In-house 13-172 (176) alignment
Range on Protein: 211-348
Range on HMM: 13-172/176.0
EIIKDFLYLGGAE----------NAGNRQQLINLKITHLVNMAGEL-----------DDVYPHLYKYYRANLDDRPKANIyEHFEPVIQFINDCKKQGGR
  | . |.||..            | . ..| .|.||..||.  |            .... . ..|.. . .|    .. |... ...||... |.||.
dyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeggp

VLIHCAMGISRSTTVVLAYLMKE-DHMTYSDAFTFCKQKRS-CINPNFGFVKQLKDYQQHL
||.|| .||.|. |.|.|||..   .... .|. . ...|. .. ........|... ..|
vlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll

0037934 (Phosphotyrosine protein) phosphatases II 211-348 3.2e-26 87.8 In-house 41-241 (243) alignment
Range on Protein: 211-348
Range on HMM: 41-241/243.0
EIIkDFLYLGGA--------ENAGNRQQLINLKITHLVNMAGEL---------------------------------------------DDVYPHLYKYY
..  . |.....          | . . | .|.||..|..  .                                              ||.. . ..|.
yvt.prliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrlvihyh

RANLDD----RPKANIYEHFEPVIQFIND-----CKKQGGRVLIHCAMGISRSTTVVLAYLMKED-HMTYSDAFTFCKQKRSC-INPNFGFVKQLKDYQQ
. .  |       ........ |..||..     . ..||.||.|| .|..|. |...||||..  .... .|. . ...|.. . ..... ..| .. .
ylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrflyeall

HL
.|
el

subfamily_DSP19_pd Subfamily DSP19 212-348 3e-44 145.0 In-house 14-150 (152) alignment
Range on Protein: 212-348
Range on HMM: 14-150/152.0
IIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMK
 ... ||||  . | ....| . ||||..|.| ....|.|. ..|   .. | |.... .... ...||.. ... |.||.||  |.|||..||.|||||
eveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmk

EDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
. ......|.. ....| ||.|| ||.||||.|...|
keelsleealelvrearpcikPneGFikqLkeyeael

subfamily_DSP8_pd Subfamily DSP8 212-349 4.2e-31 101.7 In-house 17-155 (159) alignment
Range on Protein: 212-349
Range on HMM: 17-155/159.0
IIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDD-VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLM
 | ..||||  ... ... | .| |.. .|.  .  .    .  |. |  . |. . .. . |.  ..||. .|.. ||||.|.  |||||.||..||.|
rilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayim

KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLT
|. .|.. .|..| |.||  |.||. |..|| .|...|.
ktlemsldeayrfvkekrptispnlnflgqLleyekelk

0036282 (Phosphotyrosine protein) phosphatases II 212-347 1.1e-26 89.0 In-house 14-168 (174) alignment
Range on Protein: 212-347
Range on HMM: 14-168/174.0
IIKDFLYLGGAENAgNRQQLINLKITHLVNMAGEL---------------DDVYPHLYKYYRANLDDRPKANIYEhFEPVIQFINDCKKQ--GGRVLIHC
.| . |..|..  | . ..| .|.||..|..  |                .| ... ..|.. . .|.   .. . .. ...|.... ..  || ||.||
yitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHC

AMGISRSTTVVLAYLMKEDHM-TYSDAFTFCKQKR---SCINPNFGFVKQLKDYQQH
 .|..|. |.|.||||.  .. .. ||. . ...|   ... ..... ..| .... 
saGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekl

0051082 (Phosphotyrosine protein) phosphatases II 212-344 1.6e-23 78.4 In-house 10-149 (151) alignment
Range on Protein: 212-344
Range on HMM: 10-149/151.0
IIKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHLY------KYYRANLDDRPKANIYEHFEPVIQFINDCKKQ-GGRVLIHCAMGISRSTTV
 . ..||..|.  | . ..| .|.|.. ||. .|    | . |      ....  ..| |  .. ..|. |..|.. . .. .| ||.|| .|..|. |.
yvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtl

VLAYLMKeDHMTYSDAFTFCKQKRS-CINPNFGFVKQLKDY
|..|||.  .... .|. . ..||  ...|| .|..||...
valylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal

subfamily_DSP14_pd Subfamily DSP14 213-349 8.5e-42 136.8 In-house 10-145 (157) alignment
Range on Protein: 213-349
Range on HMM: 10-145/157.0
IKDFLYLGgAENAGNRQQLINLKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKE
|.. |.|. .  | ....| . |||. .|.. || .   .  .. .  ..|.|.|....||..|.. |.. ||.||..|.||..|.||| ...|||||| 
itpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmky

DHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLT
 ...  .|..  |..|. |.|| || ||| || ..|.
eklsLreayklvksaRpiirPNvGFwkqlidyEkklk

subfamily_DSP12_pd Subfamily DSP12 213-349 7e-36 118.0 In-house 5-144 (155) alignment
Range on Protein: 213-349
Range on HMM: 5-144/155.0
IKDFLYLGGAENAGNRQQLINLKITHLVNMAGE-LDDVYPHLYK--YYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYL
|.. |||||.|.. . ..| .|||||.. .. | |..  ..  |  .   ...|.|...| .|.. ...||... ...| ||.||..|.||| |.|.|||
ilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYl

MKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLT
||....  ..|. . |.|.. |.|| ||..||| ...  .
mkkeklslekAlklvkekkpeiepNegFleQLklfekmgc

0049260 (Phosphotyrosine protein) phosphatases II 213-348 7.8e-30 99.0 In-house 11-149 (152) alignment
Range on Protein: 213-348
Range on HMM: 11-149/152.0
IKDFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVY---PHLYKYYRANLDDRPKANIYEHFEPVIQFIND-CKKQGGRVLIHCAMGISRSTTVVLAY
.  ....|.   | . ..| .|.||..|..  .|.. .   .....|.. . .| .  .. .... ...||.  ....||.||.||  |..|. |.|.||
fiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaay

LMKeDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
||.  .... .|. . ..||....||.|. ..|......|
lml.lgvsleeavalvrekRpgavpnpgqlrflyefekll

0042113 (Phosphotyrosine protein) phosphatases II 213-347 1.8e-24 81.9 In-house 50-241 (245) alignment
Range on Protein: 213-347
Range on HMM: 50-241/245.0
IKDFLYLGGAENAGNRQ----QLINLKITHLVNMAGEL----------------------------------------------DDVYPHLYKYYRANLD
|.. ......  ... .    .| .|.||..|..  |                                               || . . . |.. . .
itpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwp

DRPKANIYEHFEPVIQFINDCKK--QGGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQH
| . ... |... ...|.... .  ..|.||.|| .|..|. |...||||     ||  ..  .|. . ...|... ..... ..| .. ..
dhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyealle

0043147 (Phosphotyrosine protein) phosphatases II 214-350 1.3e-32 108.3 In-house 23-162 (172) alignment
Range on Protein: 214-350
Range on HMM: 23-162/172.0
KDFLYLGGAENAGNRQQLINLKITHLVNMAGE---LDDVYPHLYKYYRANLDDRPKAnIYEHFEPVIQFIND--CKKQGGRVLIHCAMGISRSTTVVLAY
 .......   | ....| .|.|||.||. ..    ...... ..|.. . .| .   . |... ...||..  ....||.||.|| .|..|. |.|.||
iatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaay

LMKeDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTL
||.  .... .|. . ..||... .|... ..|......| |
lml.lglsleeavalvrekRpgavqnpsqyrflyyfekllll

subfamily_DSP3_pd Subfamily DSP3 215-349 6.4e-36 117.4 In-house 16-158 (162) alignment
Range on Protein: 215-349
Range on HMM: 16-158/162.0
DFLYLGGAENAGNRQQLINLKITHLVNMAG-ELDDV--YPHLY-----KYYRANLDDRPKANIYEHFEPVIQFINDCKKQ-GGRVLIHCAMGISRSTTVV
. ||.|... | ....| .| |||..| |  .. .|   .. |     ||.  ..|| |.... ..||.. .||..  .|  |.||.||..|.|||.|.|
pklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlv

LAYLMKEDHMTYSDAFTFCKQKRsCINPNFGFVKQLKDYQQHLT
|||||   .||  .| .  ..|| .| || ||.|||......|.
layLmirrkmtlveairtvrkkR.eilPneGFlkqLaeldeelk

subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 215-347 1.2e-25 83.7 In-house 8-151 (154) alignment
Range on Protein: 215-347
Range on HMM: 8-151/154.0
DFLYLGGAENAGNRQQLINLKITHLVNMAGELDDVYPHL---------YKYYRANLDDRPKANIYEHFEPVIQFINDCK--KQGGRVLIHCAMGISRSTT
 |||..  . | |. .| . .|....|..   ......          ..| . .| | .. .| |... . .||.|     . ..||.|.  |.|||..
iflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaa

VVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQH
....|||.. ....| |. . |. |  |.|| ||.|||. ....
llisylmdklkislslalellkdsryiikPnqGflkqleifeke

DSPc Dual specificity phosphatase, catalytic domain 217-346 3.9e-38 125.3 Pfam-A 1-132 (133) alignment
Range on Protein: 217-346
Range on HMM: 1-132/133.0
LYLGGAENAGnRQQLINLKITHLVNMAGELDD---VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKED
||||....|   ..| .|.||. .|.. | .      .  ..| |  ..|  ...| ...| ...||......|..||.||..||||| |...|||||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

HMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
......|. | |..||.|.||.||..|| .|..
nlslneAyefvkerrskispnagflrqLleyer

DSPc Dual specificity phosphatase, catalytic domain 217-346 3.9e-38 125.3 In-house 1-132 (133) alignment
Range on Protein: 217-346
Range on HMM: 1-132/133.0
LYLGGAENAGnRQQLINLKITHLVNMAGELDD---VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKED
||||....|   ..| .|.||. .|.. | .      .  ..| |  ..|  ...| ...| ...||......|..||.||..||||| |...|||||..
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

HMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
......|. | |..||.|.||.||..|| .|..
nlslneAyefvkerrskispnagflrqLleyer

subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 217-348 7.6e-20 64.5 In-house 6-141 (145) alignment
Range on Protein: 217-348
Range on HMM: 6-141/145.0
LYLGGAENAGNRQQLINLKITHLVNMAGE----LDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKE
|| | | .| .   | .| |. .||||       .... . ..      .|    .. .||. | .||.  |..|  |..||  |.||| || .|.||| 
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

DHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
  || |.|    . .|    ||  |.|.| . .. |
cnmtlseaarqvrsnrllaypnvtflknllnlekql

0040439 (Phosphotyrosine protein) phosphatases II 227-348 7.1e-27 90.0 In-house 70-245 (249) alignment
Range on Protein: 227-348
Range on HMM: 70-245/249.0
NRQQLINLKITHLVNMAGELDD-------------------------------------------VYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDC
....| .|.||..|..  .                                               ..  ....  .  | |  .. ..||....||. .
fwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieav

KK------QGGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
.|      .||.||.|| .|..|. |...||||     || .... .|. . ...|... .|... ..| .. ..|
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallel

subfamily_STYX_pd Subfamily STYX 229-347 1.2e-28 93.3 In-house 33-156 (166) alignment
Range on Protein: 229-347
Range on HMM: 33-156/166.0
QQLINLKITHLVNMAGE-----LDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTF
..| .  |||.| .  .     .   .|. ..|   .. | .  ||  ..  | .||.|. ..||.||.|   |||||...|.||.|.   . | .||..
evlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyreafay

CKQKRSCINPNFGFVKQLKDYQQH
 ...| ||||| |||.|||.|.  
vqerrfcinpnegfvsqlkeyeai

0045450 (Phosphotyrosine protein) phosphatases II 229-348 6.1e-26 87.3 In-house 125-303 (307) alignment
Range on Protein: 229-348
Range on HMM: 125-303/307.0
QQLINLKITHLVNMAGELDD-------VY---------------------PHLYKYYRANLDDR-----------------PKANIYEHFEPVIQFINDC
..| ....|..|.. .. ..        .                      . |.... .. |                  |  .. ..||....||. .
rmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev

KK------QGGRVLIHCAMGISRSTTVVLAYLMKEDH--------MTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
.|      .||.||.|| .|..|. |...||||.. .        ... .|. . ...|... .|... ..| .. ..|
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel

0040438 (Phosphotyrosine protein) phosphatases II 229-351 3.4e-23 77.8 In-house 104-278 (317) alignment
Range on Protein: 229-351
Range on HMM: 104-278/317.0
QQLINLKITHLVNMAGELDD---------------------------VYPHLYKYYRANLDDR----------------PKANIYEHFEPVIQFINDCKK
. . ....|..|..  . ..                           .. . .....  . |                 |  .. ........|.. ...
rmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavre

Q----GGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTLE
.    || ||.|| .|..|. |...||||     || .... .|. . ...|... ..... ..| |. ... . 
aledpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkr

0039614 (Phosphotyrosine protein) phosphatases II 229-349 6.1e-21 70.6 In-house 119-289 (297) alignment
Range on Protein: 229-349
Range on HMM: 119-289/297.0
QQLINLKITHLVNMAGELDDVYpHLYKYY-------------------------------------------RANLDDRPKANIYEHFEPVIQFINDCKK
. . ....|..|..  . ..   . ..|.                                             .  |    .. |..  ........ .
rmvweqgvtvivmLtklvelgr.kcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvreala

---QGGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLT
   .||.||.|| .|..|. |...||||     || .... .|. . ...|... ..... ..| |. ..| 
elpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell

0043336 (Phosphotyrosine protein) phosphatases II 229-346 1.1e-16 56.5 In-house 106-274 (278) alignment
Range on Protein: 229-346
Range on HMM: 106-274/278.0
QQLINLKITHLVNMAGELDD---------------------------------------------VYPHLYKYYRANLDDRPKA-NIYEHFEPVIQFIND
. . .|..|..|.. .. ..                                              . . . |.  .  |     ..  ... . .... 
rmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavrea

CKKQGGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQ
.....| ||.||  |..|. |....||.     || .... .|. . ...| .. ... . ..| .. .
ledsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeall

0036941 (Phosphotyrosine protein) phosphatases II 231-350 1e-20 69.7 In-house 98-278 (297) alignment
Range on Protein: 231-350
Range on HMM: 98-278/297.0
LINLKITHLVNMAGELDDVYPHLYKYYRAN-----------------------------------------------LDDRPKANIYEHFEPVIQFINDC
. ....|..|..  . ..  .  ..|.  .                                                 . |  .. |.......||. .
vweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielv

KK------QGGRVLIHCAMGISRSTTVVLAYLM--------KEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTL
.|      .||.||.|| .|..|| |...|.||        ||  ... .|. . ...| .. ..... ..| .. ..| .
rkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellk

subfamily_DSP23_pd Subfamily DSP23 231-329 4.7e-08 27.8 In-house 27-126 (148) alignment
Range on Protein: 231-329
Range on HMM: 27-126/148.0
LINLKITHLVNMAGEL---DDVYPHLyKYYRANLDDRPkANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQK
|..| . .|| .. |     .  | |  ..| ..||       |  .  .. ... ....  | .||..|  |. |..  ||.|| ... ..| .  ...
lldlgvrylvslteegrphveatpnl.tlvrlriddyh.ppaleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrl

RS
| 
rp

0049772 (Phosphotyrosine protein) phosphatases II 232-378 4.4e-34 114.0 In-house 167-303 (314) alignment
Range on Protein: 232-378
Range on HMM: 167-303/314.0
InlkithlvnmaGEL---DDVYPHLYKYYRANLDDrPKANIYEHFEPVIQFINDCkKQGGRVLIHCAMGISRSTT-VVLAYLMKEDHMTYSDAFTFCKQK
            .||   ...  . .||.| ...| . |.. |.|. ...||... ..||.||.||..|..|..| ||.|||||  .... .|. . ..|
k...........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlk

RScINPNFGFVKQLKDYQQHLTLEWEKQEKLKKQQQQTLNINNNNTGIPLS
|. ||||.||..||..|...|    |....|||  . . ..  .. ... |
Rp.inpnpgfieqleqyefilealleylkflkkfyeyleenlldglqllis

0047943 (Phosphotyrosine protein) phosphatases II 233-341 4.8e-15 51.2 In-house 99-264 (273) alignment
Range on Protein: 233-341
Range on HMM: 99-264/273.0
NLKITHLVNMAGELDDVYPHLYKYYRANLDD----------------------------------------------RPKANIYEHFEPVIQFINDCKK-
. .....| .  . ..  .  ..|.  . ..                                               |  .. ...|....||....| 
eqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrka

-----QGGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNFGFVKQL
     ..| |..||  |..|. |.....|.     ||  ... .|. . ...| .. ... . ..|
lealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfl

0050432 (Phosphotyrosine protein) phosphatases II 233-335 1.1e-12 43.3 In-house 130-285 (308) alignment
Range on Protein: 233-335
Range on HMM: 130-285/308.0
NLKITHLVNMAGELDDVYPHLYKYYRANLD----------------------------------------------DRPKANIYEHFEPVIQFINDCKKQ
. .... | .  . ..  .  ..|.  .|.                                              . |  .. ...|....|.. ..|.
eqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrks

--GGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNF
  || ...||  |..|. |.....|.     || .... .|. . ...| .  ...
lpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtp

subfamily_RNGTT_pd Subfamily RNGTT 234-329 1.7e-06 21.8 In-house 61-155 (189) alignment
Range on Protein: 234-329
Range on HMM: 61-155/189.0
LKITHLVNMAGELDDVYPHLYKYYRANLDDRPKANIYEHFEPVIQFINDcKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRS
|  |.    . ||..   .  |   |   ..|.|.  ..|  ...  .. |.    . .||  |  |.  .. .||... ..  ..| .  .. | 
ltntsryYdkeelekegikyvklqcagkgeaPeaeqvkefiklveeffk.knpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRp

subfamily_MSG5_pd Subfamily MSG5 240-348 3.3e-15 49.6 In-house 52-160 (165) alignment
Range on Protein: 240-348
Range on HMM: 52-160/165.0
VNMAGELDDVY---PHlYKYYRANLDDrpKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFG
.|.| |..|.    |   |||  . .   ...|   .  . . |   . .. ..|.||  |.|||.....||.||   ..  ||.   | .   |.|..|
invakeindlellvpa.vkyyhieweh..dskivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsig

FVKQLKDYQQHL
.. || ...  |
lifqlmeweval

0038934 (Phosphotyrosine protein) phosphatases II 246-349 1.4e-18 62.7 In-house 72-177 (194) alignment
Range on Protein: 246-349
Range on HMM: 72-177/194.0
LDDVYPHLYKYYRANLDDR---PKANIYEHFEPVIQFINdCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLK
 .... . ..|..    |.   |  .|. .|  ......  ...|| |..|| .|..|. |.| |||..  .|.. .|  . ..||  . || .....| 
peefekagieylklpfpddgtvPsleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleall

DYQQHLT
 . ..| 
krykelr

PTPlike_phytase Inositol hexakisphosphate 254-310 8e-06 20.5 Pfam-A 93-147 (149) alignment
Range on Protein: 254-310
Range on HMM: 93-147/149.0
YKYYRANLDDRpKANIYEHFEPVIQFINDCkKQGGRVLIHCAMGISRSTTVVLAYLM
.||.|  . |  .|   |... ....|..  ..   ....| .|  |.||..  . .
vkYvRipitde.qapeeedvDafvrliksl.prdtalvfnCqaGrgRTTtamviadL

PTPlike_phytase Inositol hexakisphosphate 254-310 8e-06 20.5 In-house 93-147 (149) alignment
Range on Protein: 254-310
Range on HMM: 93-147/149.0
YKYYRANLDDRpKANIYEHFEPVIQFINDCkKQGGRVLIHCAMGISRSTTVVLAYLM
.||.|  . |  .|   |... ....|..  ..   ....| .|  |.||..  . .
vkYvRipitde.qapeeedvDafvrliksl.prdtalvfnCqaGrgRTTtamviadL

subfamily_PTPMT1_pd Subfamily PTPMT1 257-348 4.2e-17 57.1 In-house 77-168 (171) alignment
Range on Protein: 257-348
Range on HMM: 77-168/171.0
YRANLDDRPKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHL
.. .  |  .|   |. |  ..||.. ...| || .||  | .||.|.| .||||.....  .| .. |.||. |. .   .|.|. |...|
lqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekl

PTPc_DSPc_SM00012 260-346 7e-09 31.2 In-house 9-87 (105) alignment
Range on Protein: 260-346
Range on HMM: 9-87/105.0
NLDDRpkaNIYEHFEPVIQFINDCKKQG------GRVLIHCAMGISRSTTVVLAYLMKEDHMTYSdaftfckqkrsCINPNFGFVKQLKDYQQ
.  |    .. |. ..........||.       . |..||  |..|. |.|..... ..... .                | .||.|.....
gwpdh...gvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleket...........kevdifqivkelrkqRp

DSPc_SM00195 260-314 3.7e-06 21.8 In-house 164-222 (263) alignment
Range on Protein: 260-314
Range on HMM: 164-222/263.0
NLDDRPKANIYEHFEPVIQFINDCKKQ----GGRVLIHCAMGISRSTTVVLAYLMKEDH
.  . |. .. .. ..|..... .||.     | ...||  |..|. |.|.. .. .  
qyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskl

PTPc_SM00194 260-314 3.7e-06 21.8 In-house 164-222 (263) alignment
Range on Protein: 260-314
Range on HMM: 164-222/263.0
NLDDRPKANIYEHFEPVIQFINDCKKQ----GGRVLIHCAMGISRSTTVVLAYLMKEDH
.  . |. .. .. ..|..... .||.     | ...||  |..|. |.|.. .. .  
qyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskl

0051299 (Phosphotyrosine protein) phosphatases II 262-335 9.8e-13 43.7 In-house 190-272 (288) alignment
Range on Protein: 262-335
Range on HMM: 190-272/288.0
DDRPKANIYEHFEPVIQFINDCKKQ----GGRVLIHCAMGISRSTTVVLAYLM-----KEDHMTYSDAFTFCKQKRSCINPNF
 . |  .. ...|....|.....|.    || |..||  |..|. |.....|.     || .... .|. . ...| .. ...
tnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtp

0046845 (Phosphotyrosine protein) phosphatases II 263-333 3.2e-10 35.3 In-house 174-258 (284) alignment
Range on Protein: 263-333
Range on HMM: 174-258/284.0
DRPKANIYEHFEPVIQFINDCKKQ------GGRVLIHCAMGISRSTTVVLAYLMKED--------HMTYSDAFTFCKQKRSCINP
. |  .. ...|....|.......      || ...||  |..|. |.....|..|         .... .|. . ...| .   
swpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvq

0048567 (Phosphotyrosine protein) phosphatases II 265-330 9.4e-10 33.1 In-house 52-120 (157) alignment
Range on Protein: 265-330
Range on HMM: 52-120/157.0
PKANIYEHFEPVIQFINDCKKQGGRVLIHCAMGI---SRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSC
. | .|. .  . .|.......|... .|| .|    .|. |.. .||..  ..| ..|. . .. |  
nlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpg

subfamily_DSP11_pd Subfamily DSP11 265-341 3.3e-07 24.4 In-house 93-170 (178) alignment
Range on Protein: 265-341
Range on HMM: 93-170/178.0
PKANIYEHFEPVI-QFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQL
|| .....|. .. .|....|...  . .||. |. |.  ..  ||.. . .  .||    .. |        ..|.|
pkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeearGhslerenylkdL

Y_phosphatase Protein-tyrosine phosphatase 265-330 2e-06 22.8 Pfam-A 144-215 (235) alignment
Range on Protein: 265-330
Range on HMM: 144-215/235.0
PKANIYEHFEPVIQFINDCKKQG----GRVLIHCAMGISRSTTVVLAYLMKEDHMT--YSDAFTFCKQKRSC
|. .. |. ......|....|.     | |..||  |..|. |.|.. .. |   .    | . ..|. |..
pdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkq

Y_phosphatase Protein-tyrosine phosphatase 265-330 2e-06 22.8 In-house 144-215 (235) alignment
Range on Protein: 265-330
Range on HMM: 144-215/235.0
PKANIYEHFEPVIQFINDCKKQG----GRVLIHCAMGISRSTTVVLAYLMKEDHMT--YSDAFTFCKQKRSC
|. .. |. ......|....|.     | |..||  |..|. |.|.. .. |   .    | . ..|. |..
pdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkq

subfamily_CDC14_pd Subfamily CDC14 276-328 5.5e-07 23.7 In-house 252-304 (328) alignment
Range on Protein: 276-328
Range on HMM: 252-304/328.0
VIQFINDCKKQGGRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKR
| .|.. ..|  | . .||  |. |  |.. .||||. ..| ..| .. .  |
vkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricr

subfamily_PTPDC1_pd Subfamily PTPDC1 280-352 1.5e-07 26.0 In-house 108-179 (182) alignment
Range on Protein: 280-352
Range on HMM: 108-179/182.0
INDCKKQGgRVLIHCAMGISRSTTVVLAYLMKEDHMTYSDAFTFCKQKRSCINPNFGFVKQLKDYQQHLTLEW
.. . ..| .| .||  |  |   .. .||.  ...| ..| .. ..||.      . |. .|.....|.  .
vafalqeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefalfliplr

subfamily_PRL_pd Subfamily PRL 284-346 4.5e-06 20.8 In-house 87-147 (151) alignment
Range on Protein: 284-346
Range on HMM: 87-147/151.0
KKQGGRVLIHCAMGISRSTTVVlAYLMKEDHMTYSDAFTFCKQKRS-CINPNfgFVKQLKDYQQ
.. .  | .||  |. |.  .| |  . |. |.| ||  | ..||  .|| .   .| |..|..
eepkstvavhcvaGlGraPvlv.alalieaGmkyedavefirekrrgainsk..qlkflekyka