Gene DDB_G0283947 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily CUT
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP066_AA protein Get Run
DdisP066_AA_9-366 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Subfamily.CECR5.protein 10-366 8e-149 486.3 In-house 2-392 (393) alignment 
Range on Protein: 10-366
Range on HMM: 2-392/393.0
TATTTTTTTTTTTTTNDSSFGIVFDIDGVLMRDGVIIPNATQALKLLEDKEtSEPKIPYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMVAHTPVRPL
.......||....|.....||||.||||||.|....||.|..||||||||. .|.|.|..|.||.|.|||.|||.|.|..|......|.|...|.|...|
igaarflttraartrsakkfgivlDiDGvLlRgkkvipaakealklledkk.gelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkll

AEKykdYDVLLISKTHETSKKLADWYGFKNYKSLQQYIEERPFLCPSKYSTFWTQGVSSEYVIKEAKkqlPIKAIILLEDPIDWGECIQIVSDILQSKDG
|||   ||. |.....|.....|...||||...........|.|.|...|....|..|||.. ||.|   .|.||.||..|..|....|...|.|.|...
aek...ydkrllvvgqesvrevaeglGfknvvtidelvklfphldpvdlsrrlvqeksselaekelk...kieaivllgePvrWetslqlilDvllsegk

LLRKDYINRADVQSIDFHICNPDFSYAGEFVIPRYTMGAILECIKLLFKTQTGRDLIY-TLYGKPYPLTYQYGKQIISNQISKLGFNDgcILKHIYAIGD
||||.....|....|....||.|.....|...||...||.|.... |.|..||.||.| .|.|||..|||||....|..|..|||..|  ..|..|||||
llrklklltagrphipilacNvDllwmaeaklpRlghGafllllealykkltGkdLryeallGKPskltYqyaehvikrqakklgled..pvkkvyaiGD

NPYSDIKGANNLEH-----------------------EGWISILVKTGCFKGDT-------------------NHPEIPAKYVVDNVYDAVKLILKLEGQ
||.|||.|||..|.                       |||||||||||..|...                   .........||..|..|||.|||.|..
NPmsDilGAnlyerylrhdgvkkldalgseaqdpsdkegwiSiLVktGvykerdsvekvvkdseadlhghrdldlkllkpslvvndvleAvkkilkkEky
subfamily_CUT_pd Subfamily CUT 12-366 9.3e-148 482.8 In-house 2-390 (391) alignment 
Range on Protein: 12-366
Range on HMM: 2-390/391.0
TTTTTTTTTTTTTNDSSFGIVFDIDGVLMRDGVIIPNATQALKLLEDKEtSEPKIPYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMVAHTPVRPLAE
......|....|...||||||.||||||.|....||.|..||||||||. .|.|.|..|.||.|.|||.|||.|.|..|......|.|...|.|...|||
akrflqtrakrtrsassfgivlDiDGvLlRgkkvipaakealklledkk.gelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkllae

KykdYDVLLISKTHETSKKLADWYGFKNYKSLQQYIEERPFLCPSKYSTFWTQGVSSEYVIKEAKkqlPIKAIILLEDPIDWGECIQIVSDILQSKDGLL
|   ||. |.....|.....|...||||...........|.|.|...|....|..|||.. ||.|   .|.||.||..|..|....|...|.|.|...||
k...ydkrllvvgqesvrevaeglGfknvvtidelvklfphldpvdlsrrlvqeksselaekelk...kieaivllgePvrWetslqlilDvllsegkll

RKDYINRADVQSIDFHICNPDFSYAGEFVIPRYTMGAILECIKLLFKTQTGRDLIY-TLYGKPYPLTYQYGKQIISNQISKLGFNDgcILKHIYAIGDNP
||.....|....|....||.|.....|...||...||.|.... |.|..||.||.| .|.|||..|||||....|..|..|||..|  ..|..|||||||
rklklltagrphipilacNvDllwmaeaklpRlghGafllllealykkltGkdLryeallGKPskltYqyaehvikrqakklgled..pvkkvyaiGDNP

YSDIKGANNLEH-----------------------EGWISILVKTGCFKGDT-------------------NHPEIPAKYVVDNVYDAVKLILKLEGQ
.|||.|||..|.                       |||||||||||..|...                   .........||..|..|||.|||.|..
msDilGAnlyerylrhdgvkkldalgseaqdpsdkegwiSiLVktGvykerdsvekvvkdseadlhghrdldlkllkpslvvndvleAvkkilkkEky
CECR5_TIGR01456 15-365 3e-77 250.5 In-house 25-363 (370) alignment 
Range on Protein: 15-365
Range on HMM: 25-363/370.0
TTTTTTTTTTNDSSFGIVFDIDGVLMRDGVIIPNATQALKLLEDKEtSEPKIPYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMVAHTPVRPLAEKYK
. ... .  .. ..||...||||||.|   .|. |..||..| |..  . |||....|| ||..|...|...|. |. .. ...|. .|.|.. |..||.
rliskvspessskkfgfaldiDGvllrGkkpiagaskalrrLvddq.GalkiPvllltngGglseraraeelsalLgvevsplqviqshsPykklvnkye

DydVLLISKTHEtSKKLADWYGFKNYKSLQQYIEERPFLCPskYSTFWTQGVSSEYVIKEAKKQLPIKAIILLEDPIDWGECIQIVSDILQSKDglLRKD
.   .|.| . |  .. |. |||||  .....    . . |  .|..  . .  .    .  .   |.|...|.||.||   ||..||.|.|..  |. .
k..rilasGkge.vaevaegyGFknvvtvdelvryfrdidp..lsglvdeerrkksrdlpdldtkrieavlvlsdPvdWeadiqlisDvlrseg..lpge

YINRadvQSIDFHICNPDFSYAGEFVIPRYTMGAILECIKLLFKTQTGRDLIYTLYGKPYPLTYQYGKQII-SNQISKLGFNDGC-ILKHIYAIGDNPYS
 . .    |.   | | |  .| |. ..|. .|| . ... ...  ||..| |.| ||| .|||.| ....   . .. | ...   .|..|..|||| |
klgk...PslpvyisnqDLlwaaeakleRfGqGaFrllletiyqkvtgkpLryellGkPskltydyaedvlidiekrlagrkgsaapfkklymvGDnPas

DIKGANNLeheGWISILVKTGCFKGDTNHPEIPAKYVVDNVYDAVKLILKLEG
|| ||.|    |. ||||||| ..|  .. |..|. |||.| .||. ||. |.
DiiGarna...GlfsilvktgvydgadelkegkarlvvdsvseavikiLekea
Hydrolase_6 Haloacid dehalogenase-like hydrolase 31-137 1.2e-20 64.8 Pfam-A 1-100 (101) alignment 
Range on Protein: 31-137
Range on HMM: 1-100/101.0
IVFDIDGVLMRDGVIIPNATQALKLLEDKEtsepkIPYIFMTNNGGFTEEEKANKIsKVLQYNIPSDKVMVAHTPVRPLAEK-YKDYDVLLISKTheTSK
..||.||||.|.  .||.| .||| |....     .|....|||.. .||| |.|. . |....  ..|. ..|... ...| ..|  ||.| .     .
flfDvdGvLwrgdkaipgaaealkalraag.....kpvvllTNnsskseeeyakkl.eklgvdvteeqvvtsataaaeylkkrkadkkvlvigee..glr

KLADWYGF
.... .||
eelkeaGf
Chronophin_1 31-110 4.1e-09 27.2 In-house 4-78 (261) alignment 
Range on Protein: 31-110
Range on HMM: 4-78/261.0
IVFDIDGVLMRDGVIIPNATQALKLLEDKETSepkipYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMVAHTPVRPLA
. .|.||||.... ..| | .... |......     ..|.|||   |.|| |......   ........ . .  . |.
vLlDldGVlikgeeavpgAaeliealkqagke.....vlfvtNnsrrtreelaarlkrlGldavaaeeifssalaaaall
subfamily_PGP_pd Subfamily PGP 31-138 1.2e-08 25.6 In-house 2-103 (279) alignment 
Range on Protein: 31-138
Range on HMM: 2-103/279.0
IVFDIDGVLMRDGVIIPNATQALKLLEDKETSepkipYIFMTNNGGFTEEEKANKISKVLQYNIPSDKVMV-AHTPVRPLAEKYKDYDVLLISKtHETSK
..||.|||| ..  .||.| .||. |.... .      .|.|||.  ..|| ..|. |.   .. .....  |.. .. | .| ..  | .. . ... .
vlfDcDGVlWlgetaipgaaealnaLkklgKk.....vlfvtNnstksreellkkfkklgfekvkeeeilssaaaiadyLkqkkfekkvyvlge.eglke

KLADWyGFK
.| .  |..
eLkea.gie
subfamily_LHPP_pd Subfamily LHPP 32-127 2.6e-06 18.5 In-house 2-91 (227) alignment 
Range on Protein: 32-127
Range on HMM: 2-91/227.0
VFDIDGVLMRDGVIIPNATQALKLLEDKETsepkiPYIFMTNNGGFTEEEKANKISKvLQYNIPSDKVMVAHTPVRPLAEKYKDYDVLLISKTHET
. |. |||  ... ||.| .||| | ....        |.||.   .... ...... | ...  .... . . .| | .. |   .||...  |.
llDlsGvlhnedaaipgavealkrLrqagv.....kvrfvtNttkeskralverLir.lgfdveeeeiftsleaarqllrerklrpyllveddvee
Hydrolase_like HAD-hyrolase-like 270-356 2e-17 54.3 Pfam-A 2-75 (75) alignment 
Range on Protein: 270-356
Range on HMM: 2-75/75.0
YGKPYPLTYQYGKQIISNQisklgfndgciLKHIYAIGDNPYSDIKGANNLeheGWISILVKTGCFKGDT-NHPEIPAKYVVDNVYDA
.|||.| .|..  .  .             ..... |||....||..|||.   |. ||||.|| .. .  ..... ..||||....|
lgKPnpgmydkalevlgap...........psevvmiGDslatDieaAnna...GirsilVltGvsreedlklakakpdyvvddleea