Gene DUSP23 in Homo sapiens

Synonym: DUSP25, LDP-3, MOSP, VHZ, RP11-190A12.1, DUSP23

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP23
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP023_AA protein Get Run
HsapP023_AA_5-148 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0044763 (Phosphotyrosine protein) phosphatases II 3-148 8.3e-34 112.1 In-house 18-169 (178) alignment 
Range on Protein: 3-148
Range on HMM: 18-169/178.0
VQPPNFSWVLPGRLAGLALPrlPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPA-PDQIDRFVQIVDEAN-ARGEAVGV
....|.|..||| ..| . |  ......| .||..|.|.|||  ...  .|        |.. ... |||...|  ......||....||   .|..| |
sdyinaseilpglylgslpp..addlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlV

HCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPgSIETYEQEKAVFQFYQR
||  |.||.||. |.||.|..|| . .||...|. ||  ... .| . . .|..|
HCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelr
0051082 (Phosphotyrosine protein) phosphatases II 3-143 4.2e-28 93.2 In-house 3-146 (151) alignment 
Range on Protein: 3-143
Range on HMM: 3-146/151.0
VQPPNFSWVLPGrLAGLALPrLPAHYQFLLDLGVRHLVSLTERGPPHSDSCP----GLTLHRLRIPDFCPPAP----DQIDRFVQIVDEanARGEAVGVH
. ..|||.| .| |   . | |......| .||... |.|..  ..  . ..    |...... |.|...|      |.. .|......   ..  | ||
sdyinfsyvtgg.lyrsggp.ladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellld..kkngpvlvH

CALGFGRTGTMLACYLVKeRGLAAGDAIAEIRRLRPGSIETYEQEKAVF
|  | |||||. |.||.. .|. . .|..|.|. |||.. . .|   ..
CsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfql
subfamily_DSP23_pd Subfamily DSP23 4-149 8.5e-85 276.8 In-house 1-148 (148) alignment 
Range on Protein: 4-149
Range on HMM: 1-148/148.0
QPPNFSWVlPGRLAGLALPRLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTG
|||.|||| ..|||.|||||||..|..|||||||.||||||.|.||....|.|||.||||.|..|||..|...||..|.||....|||.|||.||.||||
qppffswv.ssrlaalalprlpdqyrylldlgvrylvslteegrphveatpnltlvrlriddyhppaleqvvefvrvveeaeekneavsvhcllgrgrtg

TMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ---FYQRT
|||||||||||.|||..||||.|||||||.||.||||.|..   |...|
tmlacylvkerklaaaeaiaevrrlrpgsvetveqeklvrdyetfinkt
0036282 (Phosphotyrosine protein) phosphatases II 4-145 7.1e-32 105.9 In-house 8-165 (174) alignment 
Range on Protein: 4-145
Range on HMM: 8-165/174.0
QPPNFSWVLPGRLAGLALPRlpaHYQFLLDLGVRHLVSLTERGPP-------------HSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANAR--G
 | ..|...|. .|| .  .   ....| .||....|.|.|  ..             .. .  |.....| .||...|  .....||..|.|| ..  |
spldlsyitprliagqgpla...fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsillefvkfveealsedpg

EAVGVHCALGFGRTGTMLACYLVKERGL-AAGDAIAEIRRLR---PGSIETYEQEKAVFQF
  | |||  |.|||||. |.||.. ..|  . ||.. .|.||   ||...| .| . . .|
gpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyf
0042113 (Phosphotyrosine protein) phosphatases II 4-146 5.3e-31 103.3 In-house 38-239 (245) alignment 
Range on Protein: 4-146
Range on HMM: 38-239/245.0
QPPNFSWV----LPGRLAGLALP---RLPAHYQFLLDLGVRHLVSLTERGP--------------------------------------------PHSDS
 . |.|.|     ....   . |    .......| .||....|.|||  .                                            ... |
dyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddes

CPGLTLHRLRIPDFCPPA-PDQIDRFVQIVDEANA--RGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ
  ....|.| .||...|  ......|...|..| |  ... | |||  | |||||..|.||.     ||.|. . .|..|.|. |||...| .| . . .
revihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflye

FY
. 
al
0040439 (Phosphotyrosine protein) phosphatases II 4-146 6.5e-27 90.1 In-house 21-242 (249) alignment 
Range on Protein: 4-146
Range on HMM: 21-242/249.0
QPPNFSWVLPGRLAGLAL-----------P---------------RLPAHYQFLLDLGVRHLVSLTERGP------------------------------
 |...|.|  . | || |           .                .......| .||....|.||.  .                              
lpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvev

--------------PHSDSCPGLTLHRLRIPDFCPP-APDQIDRFVQIVDEANA---RGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAE
               ...|.  | .. . .||.  |  ......|...|..|..   .|. | |||  | |||||..|.||.     ||.|. . .|...
kddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkl

IRRLRPGSIETYEQEKAVFQFY
.|. |||.....|| . . .. 
lrsqRpgavqnpeqyrflyeal
0046846 (Phosphotyrosine protein) phosphatases II 5-148 6.1e-35 115.9 In-house 9-171 (176) alignment 
Range on Protein: 5-148
Range on HMM: 9-171/176.0
PPNFSWVLPGRLAGlALP---------RLPAHYQFLLDLGVRHLVSLTERGPPHSDSCP---------GLTLHRLRIPDFCPPAPDQIDRFVQIVDEANA
.......... ..| ..|          |..  ..|..||....|.|||.   .. .||         |.. ..| .||...|  ...........||  
dldldyinanlilg.srpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdlelllellefirealk

RGEAVGVHCALGFGRTGTMLACYLVKE-RGLAAGDAIAEIRRLRP-GSIETYEQEKAVFQFYQR
.|. | |||  | |||||..|.||..  .|| . .|.|..|. || |...| || . . .|...
eggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefell
0048179 (Phosphotyrosine protein) phosphatases II 5-147 1.1e-32 108.1 In-house 1-142 (144) alignment 
Range on Protein: 5-147
Range on HMM: 1-142/144.0
PPNFSWVLPGRLAGlALPrLPAHYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPAP-DQIDRFVQIVDEANARGEAVGVHCALGFGRTG
|.|.|..|||   |  ||  . ....| .||......|||  .|..  ..|.....| .||...|   .....|.....|| ..|. | |||  |.||||
psnpseilpglylg.slp.taldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtg

TMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ
|. |.||.|..|| . .|.|..|. |||.... .| . . ....
tlvaaylmkklglsleealalvrsrrpgavpnpgqlrfLleyek
0037934 (Phosphotyrosine protein) phosphatases II 5-147 7.7e-31 102.9 In-house 36-239 (243) alignment 
Range on Protein: 5-147
Range on HMM: 36-239/243.0
PPNFSWVLPgRLAGLALP-------RLPAHYQFLLDLGVRHLVSLTERG------------------------------------------PP-HSDSCP
. |...|.| ||    .|       .| .....| .||....|.|||                                            ..    .. 
nanliyvtp.rliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrl

GLTLHRLRIPDFCPPA-PDQIDRFVQIVDE---------ANARGEAVGVHCALGFGRTGTMLACYLVKER-GLAAGDAIAEIRRLRPG-SIETYEQEKAV
.  .|.| .||...|  |... .|...| |         |. .|. | |||  | |||||..|.||.... |. . .|....|. ||| ...|..| . .
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrfl

FQFYQ
 ....
yeall
0048076 (Phosphotyrosine protein) phosphatases II 5-148 1.1e-30 101.5 In-house 1-141 (145) alignment 
Range on Protein: 5-148
Range on HMM: 1-141/145.0
PPNFSWVLPGRLAGlALPrLPAHYQFLLDLGVRHLVSLTERGPPHSdsCPGLTLHRLRIPDFCPPAP-DQIDRFVQIVDEANARGEAVGVHCALGFGRTG
|...|..|||   |  ||  . ....| |||......||   . ..    |.....| .||...|   .....|.....|| ..|. | |||  | ||||
pywpseilpglylg.slp.taldlellkdlgittvlnltselelle..rlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtg

TMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQR
|. |.||....|. . .|....|. |||.... .| . ...|...
tlvaaylmlllgvsleealelvrsqrpgavpnpgqlrflyefele
0048567 (Phosphotyrosine protein) phosphatases II 5-146 1.2e-17 58.7 In-house 4-135 (157) alignment 
Range on Protein: 5-146
Range on HMM: 4-135/157.0
PPNFSWVLPGRLAGLALPRLPA----HYQFLLDLGVRHLVSLTERGPPHSDSCPGLTLHrlripdfcppapdqidrFVQIVDEANARGEAVGVHCALGF-
  ......|.||   .|||||      ..| .| |. ..    . ||.. . .  . |.                 . .. .  . .| |. ||| .|  
ngdlieiipdrlyfallprlpkslynalyFsiddglvyedfffdfGPlnlailyrFilk.................lnkflkilelagkaiavhckaglk

--GRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFY
  |||.|...|||..  |. . .||| .|  ||||.  ...  ..  ..
krgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslyn
0041856 (Phosphotyrosine protein) phosphatases II 6-146 8.9e-31 102.3 In-house 17-167 (182) alignment 
Range on Protein: 6-146
Range on HMM: 17-167/182.0
PNFSWVLPGRLAGLALP------------RLPAHYQFLLDLGVRHLVSLTERGP-PHSDSCPGLTLHRLRIPDFCPPApdqIDRFVQIVDEANARGEAVG
......... ..|   .             .......| .||....|.|||.   |    . |.....| .||...|    .| ......|....|..| 
rdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd...ldelldfieevleeggpvl

VHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFY
|||  | |||||. |.||.|..|. . .|....|. |||...| .|   . ...
VHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlal
0043147 (Phosphotyrosine protein) phosphatases II 7-147 3.3e-33 110.2 In-house 14-158 (172) alignment 
Range on Protein: 7-147
Range on HMM: 14-158/172.0
NFSWVLPGRLAGLALPR--LPAHYQFLLDLGVRHLVSLTER-GPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDE--ANARGEAVGVHCALGFGR
..... .  .|.... |  |. ....| .||..|.|.|||.  .|   .  |.....| .||...| ......|....||  |. .|..| |||  |.||
dlyyipdrfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvpllellleflefidellalspggpvlVHCsaGvgR

TGTMLACYLVKeRGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ
|||. |.||.. .|| . .|.|..|. |||.... .| . . .| .
tgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfek
0045450 (Phosphotyrosine protein) phosphatases II 7-145 2.8e-27 91.7 In-house 88-299 (307) alignment 
Range on Protein: 7-145
Range on HMM: 88-299/307.0
NFSWVLPGRLAGLALPRLPAHY---------------QFLLDLGVRHLVSLTERGPPHS-----------------------------------------
| |.| . .|. |  ..|. ..               ..| ..||...|.|||  .  .                                         
NAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtd

--DSCPGLTLHRLRI---PDFCPP-APDQIDRFVQIVDEANA---RGEAVGVHCALGFGRTGTMLACYLVKERG--------LAAGDAIAEIRRLRPGSI
   . ...|.. .     ||.. |  .... .|...|..|..   .|. | |||  | |||||..|.||.....        . . .|....|. |||..
ldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgav

ETYEQEKAVFQF
...|| . . ..
qnpeqyrflyea
0051429 (Phosphotyrosine protein) phosphatases II 7-147 1.9e-26 88.8 In-house 15-222 (272) alignment 
Range on Protein: 7-147
Range on HMM: 15-222/272.0
NFSWVLPGRLAGLALP--RLPAHYQFLLDLGVRHLVSLTERG----PPHSDSCPGLTLHRLRIPDFCPPAP-----------------------------
....|.||||   . |    .|....| .||... |.|..       . .   ||.....| |.|...| .                             
ygrvvkpgrlyrsggplpltaadfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlll

-----------------------DQIDRFVQIVDEanarGEAVGVHCALGFGRTGTMLACYLVKeRGLA--------------AGDAIAEIRRLRPGSIE
                       ... ...... .    |..| |||. | .||||. |..|.  .|.               . .|..|.|. |||...
sagearevmhlhytdwpdhgvpqeallellellld....ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavq

TYEQEKAVFQFYQ
|.|| . ......
teeqylflyeall
PTEN_1 24-147 7.6e-24 79.6 In-house 56-190 (196) alignment 
Range on Protein: 24-147
Range on HMM: 56-190/196.0
LPAHYQFLLDLGVRHLVSLTERGPPHSDSC-------PGLTLHRLRIPDFCPPAPDQIDRFVQIVDEANAR---GEAVGVHCALGFGRTGTMLACYLVKE
..|. . |   |....|.|.|. . .. |.        |.. ... |.|. .|  ... ...  ..|.  .   |..| |||. | ||.||..|.||.. 
vaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmyk

RGLAAGDAIAEIRRLR-PGSIETYEQEKAVFQFYQ
..| | .|.. .|. | ||.... .||. . .|..
gkltadeAlelvrekRppgapnspsqerlleyfae
0049260 (Phosphotyrosine protein) phosphatases II 25-147 7.1e-31 102.3 In-house 23-147 (152) alignment 
Range on Protein: 25-147
Range on HMM: 23-147/152.0
PAHYQFLLDLGVRHLVSLTERGPPHSDSCPG-LTLHRLRIPDFCPPAPDQIDRFVQIVDEA--NARGEAVGVHCALGFGRTGTMLACYLVKeRGLAAGDA
. ....| .||....|.|||. . . . |.   . ..| .||...|  .|. .|. ...|     .|. | |||  |.|||||. |.||.. .|. . .|
adfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsleea

IAEIRRLRPGSIETYEQEKAVFQFYQ
.| .|. |||.... .| . ...|..
valvrekRpgavpnpgqlrflyefek
0045098 (Phosphotyrosine protein) phosphatases II 25-147 3.2e-28 94.3 In-house 78-269 (278) alignment 
Range on Protein: 25-147
Range on HMM: 78-269/278.0
PAHYQFLLDLGVRHLVSLTERGPP-----------------------------------------------HSDSCPGLTLHRL-RIPDFCPPAPD---Q
 .....| .||....|.|||  .                                                ... . |.| . .  .||...|  .   .
adfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilks

IDRFVQIVDEANA--------------RGEAVGVHCALGFGRTGTMLACYLVKER---GLAAGDAIAEIRRLRPG-SIETYEQEKAVFQFYQ
...... ..||..              .|. | |||  | |||||. |.||..|.   |. . .|..|.|. ||| .... || . ...| .
flellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefll
0043336 (Phosphotyrosine protein) phosphatases II 26-145 4.4e-27 90.7 In-house 103-272 (278) alignment 
Range on Protein: 26-145
Range on HMM: 103-272/278.0
AHYQFLLDLGVRHLVSLTERGP-------------------------------------------PHSDSCPGLTLHRLRIPDFCPP-APDQIDRFVQIV
 ..... .|||...|.|||                                               .. |. .. .| | .||.. |  .... .|...|
dFwrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkav

DEANA-RGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQF
.||.. ....| |||  | |||||..|.||.     ||.|. . .|..|.|. |||...| .| . ....
realedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyea
0036941 (Phosphotyrosine protein) phosphatases II 26-145 4.6e-22 74.1 In-house 93-272 (297) alignment 
Range on Protein: 26-145
Range on HMM: 93-272/297.0
AHYQFLLDLGVRHLVSLTERGPPHS------------------------------------------------DSCPGLTLHRLRIPDFCPPA-PDQIDR
 ... .....|...|.|||  .                                                   .|     .| . .||...|  |... .
dFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslld

FVQIVDEANA---RGEAVGVHCALGFGRTGTMLACYLV--------KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQF
|.. |.....   .|. | |||  | ||.||..|..|.        ||.|.   .|. ..|. |||...|.|| . . ..
fielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyea
0038934 (Phosphotyrosine protein) phosphatases II 27-148 7.8e-30 99.4 In-house 48-175 (194) alignment 
Range on Protein: 27-148
Range on HMM: 48-175/194.0
HYQFLLDLGVRHLVSLTERGPPHSDSC---PGLTLHRLRIPD-FCPPAPDQIDRFVQIVDEANAR--GEAVGVHCALGFGRTGTMLACYLVKERGLAAGD
.|  ||  .......||. ..  . .     |.. ..| .|| ...|  ....||...||| ...  |..|.|||  |.|||||..|.||.. .|. | .
rylkllnvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaee

AIAEIRRLRPGSIETYEQEKAVFQFYQR
||| .|. |||.|..... .|....|. 
AialfrekRpgaipnqdyleallkryke
0039614 (Phosphotyrosine protein) phosphatases II 27-146 5e-28 93.8 In-house 117-285 (297) alignment 
Range on Protein: 27-146
Range on HMM: 117-285/297.0
HYQFLLDLGVRHLVSLTERGPPHSdSC------------------------PGLT-----------------LHRLRIPDFCPP-APDQIDRFVQIVDEA
..... ..||...|.||.  .     |                        .| |                 .. . .||...|  ......|...|.||
FwrmvweqgvtvivmLtklvelgr.kcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrea

NA---RGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFY
.|   .|. | |||  | |||||..|.||.     ||.|. . .|..|.|. |||...| .| . .... 
laelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydal
0040438 (Phosphotyrosine protein) phosphatases II 27-145 6.9e-27 90.0 In-house 102-271 (317) alignment 
Range on Protein: 27-145
Range on HMM: 102-271/317.0
HYQFLLDLGVRHLVSLTERGPP----------------------------HsdsCPGLTLHRLRI-------------------PDFCPP-APDQIDRFV
..... ..||...|.|||  ..                            .   ..| ||..|..                   ||...|  ||.. .|.
FwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee...lagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfl

QIVDEANAR-GEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQF
..|.||... |. | |||  | |||||..|.||.     ||.|. . .|..|.|. |||...|.|| . . ..
eavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflyda
0047943 (Phosphotyrosine protein) phosphatases II 27-144 1.6e-22 75.7 In-house 93-266 (273) alignment 
Range on Protein: 27-144
Range on HMM: 93-266/273.0
HYQFLLDLGVRHLVSLTERGPP-----------------------------------------------HSDSCPGLTLHRLRIPDFCPP-APDQIDRFV
..... . .||..|.|||                                                    ..|.    .| . .||.. |  .... .|.
fwrmvweqnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefi

QIVDEANA---RGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ
..|..|..   ... | |||  | |||||..|..|.     ||.|. . .|.. .|. |||...|.|| . . .
elvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflye
0046845 (Phosphotyrosine protein) phosphatases II 27-145 5.9e-22 73.8 In-house 93-269 (284) alignment 
Range on Protein: 27-145
Range on HMM: 93-269/284.0
HYQFLLDLGVRHLVSLTERGPP----------------------------------------------HSDSCPGLTLHRLRIPDFCPPA-PDQIDRFVQ
... ... .||..|.|||                                                   . |.    .| . .||.. |. |... .|..
FwrmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflr

IVDEANAR---GEAVGVHCALGFGRTGTMLACYLVKER--------GLAAGDAIAEIRRLRPGSIETYEQEKAVFQF
.|.|.. .   |. . |||  | |||||..|..|..|.        |. . .|.. .|. |||...|.|| . |...
lvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyea
0051299 (Phosphotyrosine protein) phosphatases II 27-143 3.4e-20 68.1 In-house 108-279 (288) alignment 
Range on Protein: 27-143
Range on HMM: 108-279/288.0
HYQFLLDLGVRHLVSLTERGP------------------------------------------------PHSDSCPGLTLHRLRIPDFCPPA-PDQIDRF
... . . .||. |.||.                                                   ... |     .| . .||.. |  |... .|
FWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldf

VQIVDEANA-RGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVF
...|..|.| .|  | |||  | |||||..|..|.     ||.|. . .|.. .|. |||...| || . |.
lrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvy
0050432 (Phosphotyrosine protein) phosphatases II 29-144 1.1e-21 73.0 In-house 126-293 (308) alignment 
Range on Protein: 29-144
Range on HMM: 126-293/308.0
QFLLDLGVRHLVSLTERGPP-----------------------------------------------HSDSCPGLTLHRLRIPDFCPPA-PDQIDRFVQI
. . . .||. | ||.                                                    ..|.    .| .  ||.. |  |... .|...
rmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflel

VDEANaRGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ
|.. . .|. . |||  | |||||..|..|.     ||.|. . .|.. .|. |||...|.|| . ...
vrksl.pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyr
PTPc_motif_SM00404 29-134 1.6e-15 52.3 In-house 21-125 (140) alignment 
Range on Protein: 29-134
Range on HMM: 21-125/140.0
QFLLDLGVRHLVSLTERGPPHsDSCPGLTLHRLRIPD-FCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRR
..|  ||..| ...||  . . .. .| .. .. . |  . .  ...|. ......|...|..| |||..|  |..|. ..|| ..|.| . .|.  ...
allkklgithvinvteevslt.kensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslaeayefvke

LRpGSIE
 |  .|.
rR.piis
subfamily_DSP12_pd Subfamily DSP12 29-130 3.5e-10 34.5 In-house 21-124 (155) alignment 
Range on Protein: 29-130
Range on HMM: 21-124/155.0
QFLLDLGVRHLVSLTERGPPHSDSCPGLTLhRLRIPDFCPPAPD---QIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEI
..| .|.. |..|....  |.    .| .  .. |. .  |  |    .|. |. ..|| ....|| |||. |  |  |. . ||.|. .|   .|.  .
ellkelkithvlsvikeelpehklkkgkvs.tkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklv

RRLRP
.. .|
kekkp
DSPc Dual specificity phosphatase, catalytic domain 30-145 1.6e-15 52.1 Pfam-A 13-130 (133) alignment 
Range on Protein: 30-145
Range on HMM: 13-130/133.0
FLLDLGVRHLVSLTERGPP-HSDSCPGLTLHRLRIPD-FCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRR
.| .||. . ...|.. |  .... .  .  |. . |  .    ..... |.....| ..|. | |||. |  |..|. ..|| |...| . .|.. ...
lleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvke

LRPGSIETYEQEKAVFQF
 |.   .. .. . . ..
rrskispnagflrqLley
DSPc Dual specificity phosphatase, catalytic domain 30-145 1.6e-15 52.1 In-house 13-130 (133) alignment 
Range on Protein: 30-145
Range on HMM: 13-130/133.0
FLLDLGVRHLVSLTERGPP-HSDSCPGLTLHRLRIPD-FCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRR
.| .||. . ...|.. |  .... .  .  |. . |  .    ..... |.....| ..|. | |||. |  |..|. ..|| |...| . .|.. ...
lleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefvke

LRPGSIETYEQEKAVFQF
 |.   .. .. . . ..
rrskispnagflrqLley
subfamily_DSP6_pd Subfamily DSP6 32-127 2e-07 24.6 In-house 36-132 (158) alignment 
Range on Protein: 32-127
Range on HMM: 36-132/158.0
LDLGVRHLVSLTERGPPHSDSCPGLTLHRLRIPDFCPPA-PDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRR
 .|...... .|.  |   .. . |.  .. | |         .   .. .|||  . ..| |||  |  |. |.  .||.|.. |.  || . ...
kklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkk
0049772 (Phosphotyrosine protein) phosphatases II 33-146 1.9e-27 92.3 In-house 167-276 (314) alignment 
Range on Protein: 33-146
Range on HMM: 167-276/314.0
DlgvrhlvslTERGPPHSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEAnARGEAVGVHCALGFGRTGT-MLACYLVKERGLAAGDAIAEIRRLRP-
          .|  .|.  . .|....|. .||...| ....|.|.....||  .|..| |||. | ||||| ..|.||.| .|. . .|....|. || 
k.........eelydpelferlgikylripvpDgsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRpi

----GSIETYEQEKAVFQFY
    |.||..||   .....
npnpgfieqleqyefileal
subfamily_DSP10_pd Subfamily DSP10 33-130 4.4e-08 27.2 In-house 37-134 (159) alignment 
Range on Protein: 33-130
Range on HMM: 37-134/159.0
DLGVRHLVSLTERGPPHSDScPGLTLHRLRIPDFCPPA-PDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRP
 |.. ... .| . | ...   .|. .|. . |        . .  .. ..||. .|. | |||  |  |  |.   ||.|...|.  ||   ..  ||
rlnitavlnvttsvPnefee.ealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrp
subfamily_Paladin_pd Subfamily Paladin 49-106 5.3e-08 22.2 In-house 195-257 (314) alignment 
Range on Protein: 49-106
Range on HMM: 195-257/314.0
HSDSCPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEA-----NARGEAVGVHCALGFGRTGTML
..  .|.|. ||. .|... |  ...|...... |      .  | |.   |  | ||| | .
qlratptlsyhriplpeqkapleedldqllevlkevpsllskedgpalvFschsGkgrTttam
PTPlike_phytase Inositol hexakisphosphate 53-109 1.5e-12 42.4 Pfam-A 90-145 (149) alignment 
Range on Protein: 53-109
Range on HMM: 90-145/149.0
CPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEAnARGEAVGVHCALGFGRTGTMLACY
 .|.. .|. |.| . | ....|.||... ..  | .|. ..|  | ||| |.....
gfgvkYvRipitdeqapeeedvDafvrliksl.prdtalvfnCqaGrgRTTtamvia
PTPlike_phytase Inositol hexakisphosphate 53-109 1.5e-12 42.4 In-house 90-145 (149) alignment 
Range on Protein: 53-109
Range on HMM: 90-145/149.0
CPGLTLHRLRIPDFCPPAPDQIDRFVQIVDEAnARGEAVGVHCALGFGRTGTMLACY
 .|.. .|. |.| . | ....|.||... ..  | .|. ..|  | ||| |.....
gfgvkYvRipitdeqapeeedvDafvrliksl.prdtalvfnCqaGrgRTTtamvia
subfamily_PTPMT1_pd Subfamily PTPMT1 55-148 8.8e-16 52.8 In-house 73-167 (171) alignment 
Range on Protein: 55-148
Range on HMM: 73-167/171.0
GLTLHRLRIPDFC-PPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQR
|..  .|...||   |  ... . |.....   .|. | |||  | ||..|. ||||.|.. |   .|.  ... |.      .| ||. .... 
gveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeek
subfamily_PRL_pd Subfamily PRL 55-135 4.5e-11 37.0 In-house 55-136 (151) alignment 
Range on Protein: 55-135
Range on HMM: 55-136/151.0
GLTLHRLRIPDFCPPAPDQIDRFVQIVDEA--NARGEAVGVHCALGFGRTGTMLACYLVkERGLAAGDAIAEIRRLRPGSIET
|.... |   |  .|. . ........ |.  .. ...|.|||  |.||.  ..|  |. | |.   ||.  ||. | |.|..
gievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalali.eaGmkyedavefirekrrgains
subfamily_CDKN3_pd Subfamily CDKN3 55-147 4.2e-07 23.7 In-house 99-193 (202) alignment 
Range on Protein: 55-147
Range on HMM: 99-193/202.0
GLTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLV-KERGLAAGDAIAEIRRLRP-GSIETYEQEKAVFQFYQ
||. |   |.|   | . .  .... .  .   .    |||  |.||.  ..|| |.  .  .   |||...| |.  ..|.|  |   . .| .
glivhhypiadglvpdiasclkileelrinlkayrktlvhcygglgrsslviaclllylddtiepkdaidklrdlkgsraiqtvkqynylsefrd
subfamily_PTPDC1_pd Subfamily PTPDC1 56-147 1.2e-18 62.2 In-house 83-173 (182) alignment 
Range on Protein: 56-147
Range on HMM: 83-173/182.0
LTLHRLRIPDFCPPAPDQIDRFVQIVDEANARGeAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ
.. . . ..|.  .. ..|   |..|. |  .| .|.|||  | |||| ..|||||  . |.| .||  .|  || ||.| || . | .|..
iyvynfgwkDygvasleriLdivkvvafalqeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefal
subfamily_PTPN1_pd Subfamily PTPN1 57-139 2.6e-06 21.4 In-house 166-260 (290) alignment 
Range on Protein: 57-139
Range on HMM: 166-260/290.0
TLHRLRIPDFC-PPAPDQIDRFVQIVDEANARGEAVG---VHCALGFGRTGTM--LACYLVK--E----RGLAAGDAIAEIRRLRPGSIETYEQE
  | .. |||  | .| .  .|.. | |. .  . ||   .||. | ||.||.  . . ||.  .     ..   . . |.|. | | | | .| 
hfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadql
PTPc_DSPc_SM00012 58-140 3.2e-12 42.0 In-house 5-97 (105) alignment 
Range on Protein: 58-140
Range on HMM: 5-97/105.0
LHRLRIPDFCPPA-PDQIDRFVQIVDEANAR---GEAVGVHCALGFGRTGTMLACYLVKERGLAAG------DAIAEIRRLRPGSIETYEQEK
.| . .||.. |  .| | .... |.. .     .. | |||  | |||||. | ... ..  .        . . |.|. |||...|.||  
yhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqyl
subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 58-148 1.1e-06 23.1 In-house 142-240 (250) alignment 
Range on Protein: 58-148
Range on HMM: 142-240/250.0
LHRLRIPDFCPPAPD-QIDRFVQIVDEANAR--GEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQR
|| .  || . |.    .  ... |   . .     | |.|. | ||.|. .| . |     ||. .   . |  .|. ||...|. ||   |..  ..
lhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilk
subfamily_PTEN_pd Subfamily PTEN 61-120 3.4e-08 28.7 In-house 85-146 (184) alignment 
Range on Protein: 61-120
Range on HMM: 85-146/184.0
LRIPDFCPPAPDQIDRFVQIVDEA--NARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGD
. . | .||  . ....|. ...   . . . | |||  | ||||.....||.|.. |   .
ypfdDhnppplelleeivediekwleedkknvvvvHCkaGkGRtGvlivayllkslllekae
subfamily_DSP11_pd Subfamily DSP11 62-137 9.7e-11 35.9 In-house 86-165 (178) alignment 
Range on Protein: 62-137
Range on HMM: 86-165/178.0
RIPDFCPPAPDQIDRFVQIVD----EANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYE
..|    |  . ...| . |.    . .  .. .||||. |  ||| ..  ||..  |. . |||    . |  |.|  .
ncpGhevpkeelvkkfkeavkefleknkdndkligvhCthGvnrtGyliCrylidvegyepedaieafeearGhsleren
subfamily_PTPRA_pd Subfamily PTPRA 63-145 7.2e-07 23.4 In-house 201-290 (330) alignment 
Range on Protein: 63-145
Range on HMM: 201-290/330.0
IPDFC-PPAPDQIDRFVQIVDEAN-ARGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQF
 ||.  |  |  . .... | . |   .... |||. | |||||...   |      || .   ... ..|  ||  . | || . ... 
wPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykv
Y_phosphatase Protein-tyrosine phosphatase 64-140 6.3e-09 31.0 Pfam-A 144-227 (235) alignment 
Range on Protein: 64-140
Range on HMM: 144-227/235.0
PDFC-PPAPDQIDRFVQIVDEAN-ARGEAVGVHCALGFGRTGTMLACYLVKERGLA-----AGDAIAEIRRLRPGSIETYEQEK
|| . |  |... .... | . . |. . | |||  | |||||..|  .. |.  |       ... |.|. |||.....|| .
pdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYi
Y_phosphatase Protein-tyrosine phosphatase 64-140 6.3e-09 31.0 In-house 144-227 (235) alignment 
Range on Protein: 64-140
Range on HMM: 144-227/235.0
PDFC-PPAPDQIDRFVQIVDEAN-ARGEAVGVHCALGFGRTGTMLACYLVKERGLA-----AGDAIAEIRRLRPGSIETYEQEK
|| . |  |... .... | . . |. . | |||  | |||||..|  .. |.  |       ... |.|. |||.....|| .
pdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYi
subfamily_PTPN13_pd Subfamily PTPN13 64-144 7e-07 23.8 In-house 177-263 (273) alignment 
Range on Protein: 64-144
Range on HMM: 177-263/273.0
PDF-CPPAPDQIDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ
||   | ..... .||. | . .     . |||. | ||.||... . |     ... .   . . ..|. | | . | .|   |..
PdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvyk
subfamily_PTPN12_pd Subfamily PTPN12 64-143 2.6e-06 21.5 In-house 181-270 (290) alignment 
Range on Protein: 64-143
Range on HMM: 181-270/290.0
PDF-CPPAPDQIDRFVQIVDEANARG-EAVGVHCALGFGRTGTMLACYLVKER--------GLAAGDAIAEIRRLRPGSIETYEQEKAVF
||  .| ..... .... | | . .  . . |||. | |||||..|  .|.|          |   | ..|.|. |.  . | || . |.
PDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvy
subfamily_CDC14_pd Subfamily CDC14 65-138 1.8e-17 58.2 In-house 243-313 (328) alignment 
Range on Protein: 65-138
Range on HMM: 243-313/328.0
DFCPPAPDQIDRFVQIVDEAnaRGeAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQ
|   |    . .|..|...|  .| |. |||  |.|||||..||||.|. ...| .||| .|  ||||. .  |
DGstPsdaivkkfleiaeka..eG.aiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPGsvigpqq
subfamily_RNGTT_pd Subfamily RNGTT 68-148 1.2e-15 51.7 In-house 91-173 (189) alignment 
Range on Protein: 68-148
Range on HMM: 91-173/189.0
PPAPDQIDRFVQIVDE--ANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQR
 | ..|...| ..|.|  ..   | .||||  || ||| ....|||...  .. .|.|. .. ||  |   .  | ... |. 
aPeaeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiykedylkellrrYad
DSPc_SM00195 71-138 2.7e-06 22.3 In-house 174-250 (263) alignment 
Range on Protein: 71-138
Range on HMM: 174-250/263.0
PDQIDRFVQIVDEANAR----GEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQ
||. . ..... ... .     . . |||  | |||||...  ..     .|  .   . . |.|  |||...| ||
pdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleq
PTPc_SM00194 71-138 2.7e-06 22.3 In-house 174-250 (263) alignment 
Range on Protein: 71-138
Range on HMM: 174-250/263.0
PDQIDRFVQIVDEANAR----GEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQ
||. . ..... ... .     . . |||  | |||||...  ..     .|  .   . . |.|  |||...| ||
pdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleq
subfamily_DSP19_pd Subfamily DSP19 74-130 6.5e-08 27.0 In-house 75-131 (152) alignment 
Range on Protein: 74-130
Range on HMM: 75-131/152.0
IDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRP
... .. ..||     || |||  |  |. ..   ||.|.. |   .|. ..|  ||
lkealdFieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearp
subfamily_DSP15_pd Subfamily DSP15 74-129 1.7e-07 25.5 In-house 64-119 (151) alignment 
Range on Protein: 74-129
Range on HMM: 64-119/151.0
IDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLR
..  |... ..  ..|.| |||..|  |  |. . ||.    |   ||.  |.  |
fkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevikaaR
subfamily_DSP14_pd Subfamily DSP14 74-130 2.7e-06 21.4 In-house 69-125 (157) alignment 
Range on Protein: 74-130
Range on HMM: 69-125/157.0
IDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRP
 |. .. ..|....| .. |||. |  |  ..   ||.| . |.  .|   ..  ||
fdevadkieevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRp
subfamily_MSG5_pd Subfamily MSG5 74-124 5.7e-06 19.5 In-house 85-135 (165) alignment 
Range on Protein: 74-124
Range on HMM: 85-135/165.0
IDRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAE
. |. .|.  |..... . |||  |  |. ...  |..|  .|.  ||   
lsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydk
subfamily_DSP1_pd Subfamily DSP1 75-130 2.6e-06 21.6 In-house 82-137 (163) alignment 
Range on Protein: 75-130
Range on HMM: 82-137/163.0
DRFVQIVDEANARGEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLRP
.. .. .||... .  | .||. |  |  |.   ||.|.. .   .|   ... |.
eeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRs
subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 77-147 5.6e-07 24.1 In-house 210-287 (298) alignment 
Range on Protein: 77-147
Range on HMM: 210-287/298.0
FVQIVDE--ANARGEAVGVHCALGFGRTGTMLACYLV-----KERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQFYQ
... |     .|  ..| |.|. | ||.||  | . |     ||. .   ...  .|. |||...| || . ...  .
llrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavl
subfamily_DSP3_pd Subfamily DSP3 80-129 6.4e-07 23.1 In-house 88-138 (162) alignment 
Range on Protein: 80-129
Range on HMM: 88-138/162.0
IVDEANAR-GEAVGVHCALGFGRTGTMLACYLVKERGLAAGDAIAEIRRLR
 .||| ..    | |||. |. |  |.   ||.  | ... .|| ..|. |
fidealsqkegkvlvhcvvGvsRsatlvlayLmirrkmtlveairtvrkkR
subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 82-144 2.5e-06 21.7 In-house 191-258 (270) alignment 
Range on Protein: 82-144
Range on HMM: 191-258/270.0
DEANARGEAVGVHCALGFGRTGTMLA-----CYLVKERGLAAGDAIAEIRRLRPGSIETYEQEKAVFQ
 .  ...| . |||. | |||||..|     . | ... .     |.|.|. |.  ... || . ...
ekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflyk