Gene CECR5 in Homo sapiens

Synonym: CECR5

Gene expression: GTEx, DEPOD

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily CUT
Protein sequence
ID Type Fasta BLAST phosphatome Note
HsapP126_AA protein Get Run
HsapP126_AA_9-421 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
Subfamily.CECR5.protein 10-421 1.5e-183 600.7 In-house 2-393 (393) alignment 
Range on Protein: 10-421
Range on HMM: 2-393/393.0
LGAARGLCWRAARAaaglqgrparrcyavgpaQSPPTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGC
.||||.|..||||.                  .|...||..|||||||.||..||||| .|...|....|.|.|||||.||.||.....||..||..|..
igaarflttraart..................rsakkfgivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdv

EVDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLDMVDLERRL---KTTPLPRNDFPRIEGVLLLGEPVRWETSLQ
|||||||.|||||.||..|...||.||.||..|.|.|.||||.||||.|||...|| ||.|||.|||   |...|.......||...|||||||||||||
evdadqvllshsPlkllaekydkrllvvgqesvrevaeglGfknvvtidelvklfphldpvdlsrrlvqeksselaekelkkieaivllgePvrWetslq

LIMDVLLSNGSP--GAGLATPPYPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERRGWAAP
||.|||||.|..   . |.|...||.|.||.|.|||||||||.||.|||.|||.||..|.|.|||.|||| |.|||| |||||||..|.|||...|...|
lilDvllsegkllrklklltagrphipilacNvDllwmaeaklpRlghGafllllealykkltGkdLryeallGKPskltYqyaehvikrqakklgledp

IRKLYAVGDNPMSDVYGANLFHQYLqkaTHDGAPELGAGGTRQQQPSASQSCISILVCTGVYNPRNpqSTEPVLGGGEPPFHGHRDLcfSPGLMEASHVV
..|.||.|||||||..||||...||   .|||...|.|.|...|.||.....|||||.||||..|.  |.|.|....|...||||||  ...|...|.||
vkkvyaiGDNPmsDilGAnlyeryl...rhdgvkkldalgseaqdpsdkegwiSiLVktGvykerd..svekvvkdseadlhghrdl..dlkllkpslvv

NDVNEAVQLVFRKEGWA
|||.|||.....||..|
ndvleAvkkilkkEkya
CECR5_TIGR01456 10-371 1.6e-182 596.9 In-house 2-370 (370) alignment 
Range on Protein: 10-371
Range on HMM: 2-370/370.0
LGAARGLCWRAARAAAGLQGRPARRCYAVGPAQSPPTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGC
||..|.|..|.|||||||.||.||....|.|..|...|||.|||||||.||...|..|.||.||||..||.|..||...||.|.......|.|||||||.
lgllrllrnrlaraaaglrgrsarliskvspessskkfgfaldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglseraraeelsalLgv

EVDADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLD----MVDLERRLKTTPLPRNDFPRIEGVLLLGEPVRWETSL
||...|||.||||.|......|||.|.||.|.|.|.|.|.||.||||||||...|...|    .||.|||.|...||..|..|||.||.|..||.||...
evsplqviqshsPykklvnkyekrilasGkgevaevaegyGFknvvtvdelvryfrdidplsglvdeerrkksrdlpdldtkrieavlvlsdPvdWeadi

QLIMDVLLSNGSPGAGLATppyPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEgLMGKPSILTYQYAEDLI----RRQAERRGW
|||.|||.|.|.||..|..   |.|||..||.||||.||||..|||.|.|.|.|||||||||||.|||| |.||||.|||.||||..    .|.| |.|.
qlisDvlrseglpgeklgk...PslpvyisnqDLlwaaeakleRfGqGaFrllletiyqkvtgkpLrye.llGkPskltydyaedvlidiekrlagrkgs

AAPIRKLYAVGDNPMSDVYGAN---LFHQYLQKATHDGAPELGAGGTRQQQPSASQSCISILVCTGVYNPRNP
|||..|||.|||||.||..||.   ||.........|||.||..|..|....|.|...|.||....|.|.|..
aapfkklymvGDnPasDiiGarnaGlfsilvktgvydgadelkegkarlvvdsvseavikiLekeavknsrls
subfamily_CUT_pd Subfamily CUT 12-421 9.1e-183 598.1 In-house 2-391 (391) alignment 
Range on Protein: 12-421
Range on HMM: 2-391/391.0
AARGLCWRAARAaaglqgrparrcyavgpaQSPPTFGFLLDIDGVLVRGHRVIPAALKAFRRLVNSQGQLRVPVVFVTNAGNILQHSKAQELSALLGCEV
|.|.|..||.|.                  .|...||..|||||||.||..||||| .|...|....|.|.|||||.||.||.....||..||..|..||
akrflqtrakrt..................rsassfgivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvev

DADQVILSHSPMKLFSEYHEKRMLVSGQGPVMENAQGLGFRNVVTVDELRMAFPLLDMVDLERRL---KTTPLPRNDFPRIEGVLLLGEPVRWETSLQLI
|||||.|||||.||..|...||.||.||..|.|.|.||||.||||.|||...|| ||.|||.|||   |...|.......||...|||||||||||||||
dadqvllshsPlkllaekydkrllvvgqesvrevaeglGfknvvtidelvklfphldpvdlsrrlvqeksselaekelkkieaivllgePvrWetslqli

MDVLLSNGSP--GAGLATPPYPHLPVLASNMDLLWMAEAKMPRFGHGTFLLCLETIYQKVTGKELRYEGLMGKPSILTYQYAEDLIRRQAERRGWAAPIR
.|||||.|..   . |.|...||.|.||.|.|||||||||.||.|||.|||.||..|.|.|||.|||| |.|||| |||||||..|.|||...|...|..
lDvllsegkllrklklltagrphipilacNvDllwmaeaklpRlghGafllllealykkltGkdLryeallGKPskltYqyaehvikrqakklgledpvk

KLYAVGDNPMSDVYGANLFHQYLqkaTHDGAPELGAGGTRQQQPSASQSCISILVCTGVYNPRNpqSTEPVLGGGEPPFHGHRDLcfSPGLMEASHVVND
|.||.|||||||..||||...||   .|||...|.|.|...|.||.....|||||.||||..|.  |.|.|....|...||||||  ...|...|.||||
kvyaiGDNPmsDilGAnlyeryl...rhdgvkkldalgseaqdpsdkegwiSiLVktGvykerd..svekvvkdseadlhghrdl..dlkllkpslvvnd

VNEAVQLVFRKEGWA
|.|||.....||..|
vleAvkkilkkEkya
Hydrolase_6 Haloacid dehalogenase-like hydrolase 49-151 3.6e-21 66.5 Pfam-A 1-100 (101) alignment 
Range on Protein: 49-151
Range on HMM: 1-100/101.0
FLLDIDGVLVRGHRVIPAALKAFRRLVNSQgqlrVPVVFVTNAGNILQHSKAQELSAlLGCEVDADQVILSHSPMKLFSE--YHEKRMLVSGQGPVMENA
||.|.||||.||...|| | .|...| ...    .|||..|| ..  ... |..|.. ||..|...||. |..... . .  ...|..|| |. .. | .
flfDvdGvLwrgdkaipgaaealkalraag....kpvvllTNnsskseeeyakklek.lgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreel

QGLGF
.  ||
keaGf
Chronophin_1 49-120 7.5e-09 26.4 In-house 4-71 (261) alignment 
Range on Protein: 49-120
Range on HMM: 4-71/261.0
FLLDIDGVLVRGHRVIPAALKAFRRLVNSQgqlrVPVVFVTNAGNILQHSKAQELSAlLGCE-VDADQVILSH
.|||.||||..|....| | .. ..| . .      |.||||     ... |. |.. || . | |.... | 
vLlDldGVlikgeeavpgAaeliealkqag....kevlfvtNnsrrtreelaarlkr.lGldavaaeeifssa
subfamily_LHPP_pd Subfamily LHPP 49-121 1.1e-06 19.8 In-house 1-68 (227) alignment 
Range on Protein: 49-121
Range on HMM: 1-68/227.0
FLLDIDGVLVRGHRVIPAALKAFRRLVNSQgqlrVPVVFVTNAGNILQHSKAQELSAlLGCEVDADQVILSHS
.|||. |||  .. .|| | .| .|| ...    | | ||||. .  ... .. |.  || .|...... | .
vllDlsGvlhnedaaipgavealkrLrqag....vkvrfvtNttkeskralverLir.lgfdveeeeiftsle
subfamily_PGP_pd Subfamily PGP 49-121 1.5e-06 18.7 In-house 2-70 (279) alignment 
Range on Protein: 49-121
Range on HMM: 2-70/279.0
FLLDIDGVLVRGHRVIPAALKAFRRLVnSQGQlrvPVVFVTNAGNILQhSKAQELSALLGCE-VDADQVILSHS
.|.|.|||| .|...|| | .|. .|  . |.    |.|||| .   . ..  .  . ||.| |. .... | .
vlfDcDGVlWlgetaipgaaealnaLk.klgK...kvlfvtNnstksr.eellkkfkklgfekvkeeeilssaa