Gene PTPDC1-1 in Monosiga brevicollis

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily PTPDC1
Protein sequence
ID Type Fasta BLAST phosphatome Note
MbreP014_AA protein Get Run
MbreP014_AA_70-235 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
0045450 (Phosphotyrosine protein) phosphatases II 41-234 1.2e-29 99.5 In-house 48-303 (307) alignment
Range on Protein: 41-234
Range on HMM: 48-303/307.0
RVCKLFCKGSKCKHCDYHAHAHN----------------------PLNAFRGVNSTWVTENLLAMSRPLQGAIDAYhlPKKFAEAGITMVLNLQEPFEHS
.. .| . ..|. . |. .  |.                       .. .. ... ... . .|.  ||.. .. .   . . | |.|....| |..|. 
siallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedF..wrmlweqgvtvivmltelvelg

H---------------------------CGAGVNRHGFSYSF---ESFQQQGVTVCNCAWVDFGSPP-MERALDIVKIMASVIQ---EGGKIAVHCHAGR
.                             .|. .. .  .    ...  .    .  .| |.| || .| .||..... ....   .||...|||.|| 
rekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGv

GRTGLIIAAYLIFHND--------YTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
|||| .|||||. ..         ... .|..|.|.|||. .|. .| .|| |. ..|
gRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallel

PTEN_1 49-236 9.8e-42 138.0 In-house 2-194 (196) alignment
Range on Protein: 49-236
Range on HMM: 2-194/196.0
GSKCKHCDYHAHAHNPLNAFRGVNSTWVTENLLAMSRPLQGaIDAYHLPKKFAEAGITMVLNLQEPFEHSHCGAGVNRHG--FSYSFESFQQQGVTVCNC
....|... . .|.. . . ...........  |.||||.      .| .....    .. ||.|.  ....     ..   .||. |.|...||.. ..
srlskrsskknlalptelldltyitsriiamgkapsrpllq.eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhf

AWVDFGSPPMERALDIVKIMASVIQE---GGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQR-PKTIQTRNQVKFLEEFDMYLHP
 . |.| |.... .||.| ... ...   |....|||.||.||.|...||||.... .|| .|..|||..| |  .... | ..||.|.. |. 
pieDhgapslselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae

0039614 (Phosphotyrosine protein) phosphatases II 50-234 3.8e-30 100.8 In-house 58-288 (297) alignment
Range on Protein: 50-234
Range on HMM: 58-288/297.0
SKCKHCDYHAHAHNPLNA--FRG--VNSTWV-----------TENLLAMSRPLQGAIDAYhlPKKFAEAGITMVLNLQEPFEHSH---------------
.|. . |. .  |.      ..|   .|...           | . .|.. ||.. .. .   . . | |.|....| ...|...               
dknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedF..wrmvweqgvtvivmLtklvelgrkcaqywpeeggtygd

---------CGAGVNRHGFSYSFESFQQQGVTVCNCAWVDFGSPP-MERALDIVKIMASVIQ---EGGKIAVHCHAGRGRTGLIIAAYLI-----FHNDY
           .|...  .. . ..   .   ..   | |.| || .|  |...... ....   .||...|||.|| |||| .|||||.      . ..
ftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggv

TAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
.. .|.. .|.|||. .|| .| .|| .. ..|
dvleavkelreqRpgavqtpsqyrflydallel

subfamily_PTPDC1_pd Subfamily PTPDC1 59-241 1e-87 287.3 In-house 3-182 (182) alignment
Range on Protein: 59-241
Range on HMM: 3-182/182.0
AHAHNplNAFRGVNSTWVTENLLAMSRPLQGAIDAYHLPKKFAEAGITMVLNLQEPFEHSHCGAGVNRHGFSYSFESFQQQGVTVCNCAWVDFGSPPMER
.....  .|..|..||||||..||..|| | |||.|.| .||.|.||..|.||||..||..||||....||||..|....||..|.|..| |.|....||
wseee..qaikGlystWvtedilalarpsqeaideyklldkfkesgikavinLqekgehasCGagleesGfsYdlealmeqgiyvynfgwkDygvasler

ALDIVKIMASVIQEGgKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYLHPRRAVY
.|||||..|...||| |.|||||||.||||..||.||......||.|||.||||.|||.||||.||....||...|.|.|.||
iLdivkvvafalqeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefalfliplrkvy

0044763 (Phosphotyrosine protein) phosphatases II 64-238 2.1e-35 117.3 In-house 14-174 (178) alignment
Range on Protein: 64-238
Range on HMM: 14-174/178.0
PLNAFRGVNSTWVTENLLAMSRPLqgaidaYHLPKKFAEAGITMVLNLQEPFEHSHCGagvnrhgfsYSFESFQQQGVTVCNCAWVDFGSPP-MERALDI
 |..... | ......|...| |        . .. . | |||...|| |..|. ...         .  . ... |...... ..|.| |. .|  |..
glersdyinaseilpglylgslpp......addlellkelgithivnlteelelgflk.........cdpywpeeagiqylhipipDhgvpdllehflef

VKIMASVI-QEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPkTIQTRNQVKFLEEFDMYLHPRR
|... ... ..||...|||.||.||.|...||||. ...... .||.|||..||  .....|...|.||...|.. .
vefieealdekggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkes

0041856 (Phosphotyrosine protein) phosphatases II 64-235 6.7e-34 112.4 In-house 17-171 (182) alignment
Range on Protein: 64-235
Range on HMM: 17-171/182.0
PlnafrgvNSTWVTENLLAMSRPLQGAIDA--------YHLPKKFAEAGITMVLNLQepfehshcgagvnrhGFSYSFESFQQQGVTVCNCAWVDFGSPP
.       .......||...|.| .  | .        ..  . . | |||...||                .. |  | ....|.....  | |.| |.
r.......dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt...............eelywpellerlgiqylylpwpDhgvpd

MERALDIVKIMASviqEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYLH
.. .||..... .   |||...|||.||.|||| ..||||. ...... .|..||||.||. ..| ||  ||  . ..|.
ldelldfieevle...eggpvlVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallell

0037934 (Phosphotyrosine protein) phosphatases II 66-233 1.2e-32 108.8 In-house 32-240 (243) alignment
Range on Protein: 66-233
Range on HMM: 32-240/243.0
NAFRGVNSTWVTENLLAMSRPLQGAIDA--YHLPKKFAEAGITMVLNLQEPFEHSHCGAGVN------------------------RHGFS---YSFESF
. .   | ..||..| |.. ||.. ..   ..  . . | |||....| |..|.....                             . ..   .. . .
sdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddl

QQQGVTVCNCAWVDFGSPP-MERALDIVKIMASVIQE---------GGKIAVHCHAGRGRTGLIIAAYLIFHN-DYTAAKAIRLVRSQRPK-TIQTRNQV
..... ..  .| |.| |. .|  ||..... ..|.|         ||...|||.||.||||..|||||. .. .... .|..|.|.|||   .||..| 
trlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqy

KFLEEFDMY
.|| |. ..
rflyealle

0042113 (Phosphotyrosine protein) phosphatases II 69-234 1.2e-31 105.4 In-house 43-242 (245) alignment
Range on Protein: 69-234
Range on HMM: 43-242/245.0
RGVNSTWVTENLLAMSRPLQGaiDAYHLPKKFAEAGITMVLNLQEPFEHSHC--------------------------GAGVNRHGFSYS--FESFQQQG
  |.  ..|....|.. ||..  .  .  . . | |||....| |..|....                           ... .  .. .   .......
syvdgyritpkfiatqgPlpe..tvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrev

VTVCNCAWVDFGSPP-MERALDIVKIMASVIQ--EGGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDM
....   | |.| |. .|  ||..... ....  ..|...|||.||.||||..|||||.      . .... .|.. .|||||. .|| .| .|| |. .
ihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeall

YL
.|
el

0040439 (Phosphotyrosine protein) phosphatases II 69-234 7e-29 96.6 In-house 34-245 (249) alignment
Range on Protein: 69-234
Range on HMM: 34-245/249.0
RG-----------VNSTWVTENLLAMSRPLQGAIDAYhlPKKFAEAGITMVLNLQEPFEHSHCG--AGVNRHGFS-------------------------
.|           .. .... ...|.. ||.......   . . | |||....| ...|. ...     .  |.                          
pglflsdyinAsyidgyyikrrfiatqgPlpetvedf..wrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtlel

---YSFESFQQQGVTVCNCAwvDFGSP-PMERALDIVKIMASVIQ---EGGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTI
   |  ||.. ... . ..   |.| |  .| .||..... ....   .||...|||.|| ||||..|||||.      ......  |..|.|||||. .
tnlydgesrtvlhiqytdwp..dhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgav

QTRNQVKFLEEFDMYL
|. .| .|| |. ..|
qnpeqyrflyeallel

0046846 (Phosphotyrosine protein) phosphatases II 70-234 4e-40 132.8 In-house 9-172 (176) alignment
Range on Protein: 70-234
Range on HMM: 9-172/176.0
GVNSTWVTENLLAMSRPLQGAID----AYHLPKKFAEAGITMVLNLQEPFEHSHCGagvnrhgFSYSFESFQQQGVTVCNCAWVDFGSPPMERALDIVKI
. .......||...|||. .  .     ..  . . |.|||.|.||.|..|.....       . . .. ... |...... |.|.| |..|  |.....
dldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlk.......cpnywpeleklgiqylhlpwpDhgvpdlelllellef

MASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFH-NDYTAAKAIRLVRSQRP-KTIQTRNQVKFLEEFDMYL
. ....|||...|||.||.||||...||||. . ..... .|..|||.||| . .||..|..||.|| ..|
irealkeggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefelll

subfamily_Tensin_pd Subfamily Tensin 70-204 1.9e-10 33.6 In-house 10-135 (189) alignment
Range on Protein: 70-204
Range on HMM: 10-135/189.0
GVNSTWVTENLLAMSRPLQGAIDAYHlpKKFAEagITMVlnLQEPFEHSHcgAGVNRHGFSYSFESFQQQgvtVCNCAWVDFGSPPMERALDIVKIMASV
... |..|| ..|.| | .|  ..|   ... .  .. .  |..  ...      |    .|  ......   | .  | |  .|..|.   |.| . | 
dldltyiteriialsfpaegleekyr..enlkd..vakl..lkskhndky..lvfnlsekrydisklnkk...vldfGWPdllaPsleklcsicksldsW

IQEGGK--IAVHCHAGRGRTGLIIAAYLIFHNDYTAA
...  .  ..|||. |.||.|....||. . .  ..|
lkadpqnvvvvhckGgkgrigvvvsaymkyskisasa

0036282 (Phosphotyrosine protein) phosphatases II 71-234 2.2e-34 114.0 In-house 10-169 (174) alignment
Range on Protein: 71-234
Range on HMM: 10-169/174.0
VNSTWVTENLLAMSRPLQgaidayhLPKKFAEAGITMVLNLQEPFEHSHCGAGVNRHGfsySFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASVI
.. ...|..|.|.. ||.         . . | |||.|..| |..|  ...            |.. . |.... . |.|.| |...  |..||.. ...
ldlsyitprliagqgpla.......fwemlkelgittvvmlleekelglykcinywpe...lredlerlgiqylylpwpDhgvpdlsillefvkfveeal

QE--GGKIAVHCHAGRGRTGLIIAAYLIFHNDY-TAAKAIRLVRSQR---PKTIQTRNQVKFLEEFDMYL
.|  ||...|||.||.||||...||||. .. . .. .|..|||..|   |. .|| .| .|| .|...|
sedpggpvlVHCsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfekll

0043147 (Phosphotyrosine protein) phosphatases II 71-236 2.4e-34 113.9 In-house 13-162 (172) alignment
Range on Protein: 71-236
Range on HMM: 13-162/172.0
VNSTWVTENLLAMSRPlqGAIDAYHLPKKFAEAGITMVLNLQEPfehshcgagvnrhgfSYSFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMAS--
.. .... ...|.  |  .  .  .  . . | |||...|| |                 |  | ....|.... . | |.| |..|  |...... .  
ldlyyipdrfiatqgp..lrntladfwrmlkelgithivnltel...............lydpellerlgiqylylpwpDhgvpllellleflefidell

VIQEGGKIAVHCHAGRGRTGLIIAAYLIFhNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYLHP
....||...|||.|| ||||...||||.   .... .|..|||..||. .|. .| .|| .|. .|. 
alspggpvlVHCsaGvgRtgtlvaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfekllll

0043336 (Phosphotyrosine protein) phosphatases II 71-233 1.9e-28 95.2 In-house 81-275 (278) alignment
Range on Protein: 71-233
Range on HMM: 81-275/278.0
VNSTWVTENLLAMSRPLQGAIDAYhlPKKFAEAGITMVLNLQEPFEHSHC-------------------------GAGVNRHGFSYS--FESFQQQGVTV
|.  .|... .|.. ||.. .. .   . . | |.|....| |..|....                          ... .. .  .   ... .... .
vdgynvprkfiatqgPlpetvedF..wrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthy

CNCAWVDFGSP-PMERALDIVKIMASVIQ-EGGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMY
.  .| |.| | ...  ||..|.. .... ..|...|||.|| ||||..||.||.      .  ... .|.. .|.|||. .|| .| .|| |. ..
hylgwpdhgvpeslsllldflkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle

0040438 (Phosphotyrosine protein) phosphatases II 71-242 5.1e-27 90.4 In-house 79-283 (317) alignment
Range on Protein: 71-242
Range on HMM: 79-283/317.0
VNSTWVTENLLAMSRPLQGaiDAYHLPKKFAEAGITMVLNLQEPFEHS---------------------------HcGAGVNRHGFSYSF-ESFQQQGVT
|.  . . . .|.. ||..    ..  . . | |.|....| |..| .                           .  ||.. . .  .  .. ..  ||
vdgpnlkrkfIatqgPlpn..tvedFwrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseee.lagitlrtlevedlgdsesrtvt

VCNCAW-VDFGSPP-MERALDIVKIMASVIQE-GGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
.  . .  |.| || ..  ||..... ..... ||...|||.|| |||| .|||||.      ...... .|.. .|.|||. .|| .| .|| .. ...
hfhytgWpdhgvppspdllldfleavrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalley

HPRRAVYH
. |. .. 
lkrkltle

0051082 (Phosphotyrosine protein) phosphatases II 71-227 9.4e-27 88.9 In-house 6-145 (151) alignment
Range on Protein: 71-227
Range on HMM: 6-145/151.0
VNSTWVTENLLAMSRPLQgaidayHLPKKFAEAGITMVLNLQEPFEHShcgagvnrhgfsYSFESFQQQGVTVCNCAWVDFGSPPM----ERALDIVKIM
 | ..||..|.... ||.      .  . ..| ||....|| ...|.             |  | ....|..|... ..|.  |..    . .|......
infsyvtgglyrsggpla......dflellkelgiktivnlrseeerg............ycpeylpelgievlhipildwpdpglplsfdavleflell

ASviQEGGKIAVHCHAGRGRTGLIIAAYLIFhNDYTAAKAIRLVRSQRPKTIQTRNQVKFL
..  ...|...|||.||.||||...|.||.   ......|.. .|..||  .|. .|  |.
ld..kkngpvlvHCsaGkgRTGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfq

subfamily_VSP_pd Subfamily VSP 72-206 1.4e-09 32.2 In-house 35-161 (212) alignment
Range on Protein: 72-206
Range on HMM: 35-161/212.0
NSTWVTENLLAMSRPLQGAIDAYHLPKKfaEagITMVLNLQEPFEHSHCGAGVNRHgfsYSFESFQQQgvtVCNCAWVDFGSPPMERALDIVKIMASVIQ
. |.||| ..||| |  |    |  | .  |  ..  |. . . ..       .|.   |  . |...   | ..   |   | .|. | . |..   ..
dltyvteriiamsfpssGkqslyrnpis..e..varfldtkhrdhykvvnlcsera...ydekyfnnr...vkriliddhnvpkleellvftkevkewle

EGGK--IAVHCHAGRGRTGLIIAAYLIFHNDYTAAKA
.  |  .|.||  |.|||| |. |.|.  . .. || 
kdlknvlaihckGGkgrtGtivcalllaseifetake

0038934 (Phosphotyrosine protein) phosphatases II 73-230 3.8e-33 110.2 In-house 13-172 (194) alignment
Range on Protein: 73-230
Range on HMM: 13-172/194.0
STWVTENLLAMSRPLQGAIDAYhlPKKFAEAGITMVLNLQEPFEHsHCGAGVNR--HGFSYSFESFQQQGVTVCNCAWVDFG-SPPMERALDIVKIMASV
....|....|...||.| .| |   . .   ........ . . . ..|. ..   ... |. | |.. |... .. ..|.| .|..|  |......  .
gdiitgrfiafkvPlsgsldky..ieelyrfspedlvrylkllnv.klglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdef

IQE--GGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEF
..|  ||..||||.||.||||...||||| .....| .||.|.|. ||. |....... | ..
lnedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialfrekRpgaipnqdyleallkr

0046845 (Phosphotyrosine protein) phosphatases II 73-230 5e-22 74.0 In-house 72-269 (284) alignment
Range on Protein: 73-230
Range on HMM: 72-269/284.0
STWVTENLLAMSRPLQGAIDAYHlpKKFAEAGITMVLNLQEPFEHSH--C-------------------------GAGVNRHGFSYSF---ESFQQQGVT
 |... . .|.. ||.. .. .   .   | .....  | |..| ..  |                           .. .. .. ..   ...  .   
ltyikkkfIatqgPlpntvedFw..rmvweqnvrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvth

VCNCAWVDFGSPP-MERALDIVKIMASVIQE---GGKIAVHCHAGRGRTGLIIAAYLIFHN--------DYTAAKAIRLVRSQRPKTIQTRNQVKFLEEF
 .  .| |.| || .|  |...... .....   ||.|.|||.|| |||| .||..|...          ... .|.. .|.|||  .||  | .|. |.
fhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyea





subfamily_PTEN_pd Subfamily PTEN 74-232 1.1e-12 43.4 In-house 23-177 (184) alignment
Range on Protein: 74-232
Range on HMM: 23-177/184.0
TWVTENLLAMSRPLQGAIDAYHLPKKfaeaGITMVLNLQEpfeHSHCGAGVNRHGFSYSFESFQQQgvtVCNCAWVDFGSPPMERALDIVKIMASVIQEG
...|||..||. | ..   .|   ..     .. .|. .    . |      | . .|. ..|...   |  .   |  .||.|   .||. . . ..| 
syiteniiamgyPaeklealyRnsle....dvvkflekkh...kdhykiynlrserkydskkfdgr...vavypfdDhnppplelleeivediekwleed

GK--IAVHCHAGRGRTGLIIAAYLIFHNDYTAA-KAIRL---VRSQRPKTIQTRNQVKFLEEFDM
 |  ..|||.||.||||..|.|||. .. .. | .|..|   .|..  |...   | ...| .. 
kknvvvvHCkaGkGRtGvlivayllkslllekaeealelfaeaRtknkkgvtiPsqrRYveYyek

0051429 (Phosphotyrosine protein) phosphatases II 75-234 6.7e-25 83.7 In-house 18-224 (272) alignment
Range on Protein: 75-234
Range on HMM: 18-224/272.0
WVTEN-LLAMSRPLQGaiDAYHLPKKfAEAGITMVLNLQEPFEHSHCGAGVNRHGFSYSFESFQQQGVTVC-----------------------------
.| .. |.....||.   .| ....  .| ||.....| ...|. ...     .|. | . ..   ...                               
vvkpgrlyrsggplpl..taadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlll

------------NCAWVDFGSPPmERALDIVKIMASviqeGGKIAVHCHAGRGRTGLIIAAYLIFhNDYT--------------AAKAIRLVRSQRPKTI
             ..|.|.| |. |  |........    ||.. |||.||..|||...|..|.   . .              ...|.. .|.|||. .
sagearevmhlhytdwpdhgvpq.eallellellld....ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgav

QTRNQVKFLEEFDMYL
||  |..|| |. . |
qteeqylflyeallel

0036941 (Phosphotyrosine protein) phosphatases II 91-237 2.1e-23 78.5 In-house 71-279 (297) alignment
Range on Protein: 91-237
Range on HMM: 71-279/297.0
IDAYHLPKKFA------------------EAGITMVLNLQEPFEHSHC------------------------------GAGVNRHGFSYSF-ESFQQQGV
.| |.|..||                   | ..|....| |..|                                   ... .. .  .. .. ..  |
vdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtv

TVCNC-AWVDFGSPP-MERALDIVKIMASVIQ---EGGKIAVHCHAGRGRTGLIIAAYLI--------FHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLE
|.. .  | |.| |. ..  ||... . .|..   .||.. |||.|| ||.| .|||.|.         .. ..  .|.. .|.|||  .|| .| .|| 
thfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrfly

EFDMYLHPR
|. ..|  .
eallellkk

0045098 (Phosphotyrosine protein) phosphatases II 93-236 1.4e-30 102.1 In-house 77-273 (278) alignment
Range on Protein: 93-236
Range on HMM: 77-273/278.0
AYHLPKKFAEAGITMVLNLQEPFEHS---------------------------HCGAGVNRHGFSYSF----ESFQQQGVTVCNC-AWVDFGSPPME---
. .  . . | ||| ...| | .| .                           ...  . |.   . .    |.... |||. ..  | |.|.|...   
vadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilk

RALDIVKIMASVIQ--------------EGGKIAVHCHAGRGRTGLIIAAYLIFHN---DYTAAKAIRLVRSQRPK-TIQTRNQVKFLEEFDMYLHP
  |.... . ....              .||...|||.|| |||| ..||||. ..    ... .|.. .|||||   .|. .| .||.|| ..|. 
sflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelll

0048076 (Phosphotyrosine protein) phosphatases II 96-235 1.2e-31 104.7 In-house 21-143 (145) alignment
Range on Protein: 96-235
Range on HMM: 21-143/145.0
LPKKFAEAGITMVLNLqepfehshcgagvnrhgfSYSFESFQQQGVTVCNCAWVDFGSPPM-ERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAY
  . ... |||.||||                  .. .| . ..|...... | |.| |.. |  |...... ....|||...|||.||.||||...|||
dlellkdlgittvlnl..................tselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaay

LIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYLH
|........ .|..|||||||. ... .|..||.||...|.
lmlllgvsleealelvrsqrpgavpnpgqlrflyefelell

0048179 (Phosphotyrosine protein) phosphatases II 97-232 3.7e-31 103.2 In-house 22-142 (144) alignment
Range on Protein: 97-232
Range on HMM: 22-142/144.0
PKKFAEAGITMVLNLQEPFEHSHCGAGvnrhgfsysfesfqqqGVTVCNCAWVDFGSPPM-ERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYL
 . ... |||.|.||.|..|. ...                  |...... | |.| |.. |  |...... ....|||...|||.||.||||...||||
lellkklgittvinlteeyepeflere................giqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaayl

IFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDM
........ .|..||||.||  .....|..||.|.. 
mkklglsleealalvrsrrpgavpnpgqlrfLleyek

PTPc_motif_SM00404 97-229 8.3e-18 59.6 In-house 20-136 (140) alignment
Range on Protein: 97-229
Range on HMM: 20-136/140.0
PKKFAEAGITMVLNLQEPFEHShcgagvnrhgfsysfesFQQQGVTVCNCAWVDFGSPPMERALDI-VKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYL
|.. .. |||.|.|..|  . .                  ...|......   | .. .. . ||  .... .....|||. ||| ||  |.. .|.|||
pallkklgithvinvteevslt.................kensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYl

IFHNDYTAAKAIRLVRSQRpKTIQT-RNQVKFLEE
.  . ...|.|...|...| ..|.   | |. | |
mryrqlslaeayefvkerR.piispnlnfvrqLie

0049260 (Phosphotyrosine protein) phosphatases II 98-231 2.7e-29 97.2 In-house 27-146 (152) alignment
Range on Protein: 98-231
Range on HMM: 27-146/152.0
KKFAEAGITMVLNLQEPFEHSHCGAGVNRhgfsysfesfqqqgvTVCNCAWVDFGSPPMERALDIVKIMASV--IQEGGKIAVHCHAGRGRTGLIIAAYL
. . | ||| ...| |..|  ...                    ..... | |.| |...  |... ..     ...||...|||.|| ||||...||||
rmlkelgittivmltellelgklkceqyi...............qylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaayl

IFhNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFD
.  ..... .|..|||..||. ... .| .|| ||.
ml.lgvsleeavalvrekRpgavpnpgqlrflyefe

subfamily_CDC14_pd Subfamily CDC14 98-229 1.5e-17 58.5 In-house 206-318 (328) alignment
Range on Protein: 98-229
Range on HMM: 206-318/328.0
KKFAEAGITMVLNLQEPfehshcgagvnrhgfSYSFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASViqeGGKIAVHCHAGRGRTGLIIAAYLIF
. |.. ..| |. | .                 |  ..|...|.   .  ..| . |. .     ..|. ..    |.|||||.|| |||| .||.||. 
eyfrknnvttvvrLnkk...............lYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaeka...eGaiavhCkaGLGrtGtLiacylmk

HNDYTAAKAIRLVRSQRPKTIQTRnQVKFLEE
|  .||| ||  .|  || .. .  | |||||
hyrftaaeaiawlricrPGsvigp.qqkflee

DSPc Dual specificity phosphatase, catalytic domain 98-230 1.8e-17 58.4 Pfam-A 12-130 (133) alignment
Range on Protein: 98-230
Range on HMM: 12-130/133.0
KKFAEAGITMVLNLQEPFEHShcgagvnrhgF----------SYSFESfqqqgvtvcncawvdFGSPPMERAL-DIVKIMASVIQEGGKIAVHCHAGRGR
.. .. |||.|.|...  ...          .          ..  |                . .  ... | ..|.......|.|.|..||| ||  |
alleklgitlvinvtkevpnn..........naikkseieylripved...............etetkiskeleeavefiekaeqkgkkvlVHCqaGisR

TGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEF
.. .|.|||.  . ... .|...|...|.|  .. .... | |.
SatliiaYlmktknlslneAyefvkerrskispnagflrqLley

DSPc Dual specificity phosphatase, catalytic domain 98-230 1.8e-17 58.4 In-house 12-130 (133) alignment
Range on Protein: 98-230
Range on HMM: 12-130/133.0
KKFAEAGITMVLNLQEPFEHShcgagvnrhgF----------SYSFESfqqqgvtvcncawvdFGSPPMERAL-DIVKIMASVIQEGGKIAVHCHAGRGR
.. .. |||.|.|...  ...          .          ..  |                . .  ... | ..|.......|.|.|..||| ||  |
alleklgitlvinvtkevpnn..........naikkseieylripved...............etetkiskeleeavefiekaeqkgkkvlVHCqaGisR

TGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEF
.. .|.|||.  . ... .|...|...|.|  .. .... | |.
SatliiaYlmktknlslneAyefvkerrskispnagflrqLley

subfamily_DSP3_pd Subfamily DSP3 98-215 1.7e-12 41.3 In-house 30-139 (162) alignment
Range on Protein: 98-215
Range on HMM: 30-139/162.0
KKFAEAGITMVLNLQEPfEHSHcgagVNRHGFSYSFESFQQQGVTVCNCAWVDFgSPPMERALDIvkIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIF
.|....||| |||  |  ..|.    |. .   |.  ...  |. | .   .|. |   |.| .   | ... |. ||. |||..|  |   .. |||. 
skLkklGithvlnaaeg.rfsk....vdtgaefykdleikylGlevdDvpefdl.skyFetaakf..idealsqkegkvlvhcvvGvsRsatlvlayLmi

HNDYTAAKAIRLVRSQRP
... |. .||| ||..| 
rrkmtlveairtvrkkRe

subfamily_Laforin_pd Subfamily Laforin 99-217 2.9e-08 26.8 In-house 32-154 (183) alignment
Range on Protein: 99-217
Range on HMM: 32-154/183.0
KFAEAGITMVLNLQEPFEHSHCGAGVNRHGFSYS---FESFQQQGVTVCNCAWVDFGSPP-MERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAY
.. . ||| |..||  ..  .  .|..|.  .        ....|..       |. .   .|   . | .. .....| .. ||| || ||.  |.  .
dlksegitavislqtesdivknssgiyrynenlpitlkklykeeglayiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgf

LIFHNDYTAAKAIRLVRSQRPKT
| .  ... ||    . ..|| .
lqyvlgwslakvqyfllakrpvv

DSPc_SM00195 122-228 2.5e-10 35.5 In-house 140-255 (263) alignment
Range on Protein: 122-228
Range on HMM: 140-255/263.0
AGVNRHGFSYSFES-FQQQGVTVCNC-AWVDFGSP-PMERALDIVKIMASVIQ-EGGKIAVHCHAGRGRTGLIIAAYLIFH-----NDYTAAKAIRLVRS
. .... .....|   ... ||. .. .| | | |  ..  |.... . .  . . | | |||.|| |||| .... .| .     ...   . .. .|.
deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRk

QRPKTIQTRNQVKFLE
|||. .||..| .|. 
qRpgmvqtleqYlfiy

PTPc_SM00194 122-228 2.5e-10 35.5 In-house 140-255 (263) alignment
Range on Protein: 122-228
Range on HMM: 140-255/263.0
AGVNRHGFSYSFES-FQQQGVTVCNC-AWVDFGSP-PMERALDIVKIMASVIQ-EGGKIAVHCHAGRGRTGLIIAAYLIFH-----NDYTAAKAIRLVRS
. .... .....|   ... ||. .. .| | | |  ..  |.... . .  . . | | |||.|| |||| .... .| .     ...   . .. .|.
deiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRk

QRPKTIQTRNQVKFLE
|||. .||..| .|. 
qRpgmvqtleqYlfiy

subfamily_PTPN9_pd Subfamily PTPN9 122-226 1.9e-06 22.1 In-house 169-281 (297) alignment
Range on Protein: 122-226
Range on HMM: 169-281/297.0
AGVNRHGFSYSFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASV---IQEGGKIAVHCHAGRGRTGLIIA-----AYLIFHNDYTAAKAIRLVRSQ
 . .|.   . | |.   ||     . .|. .   |.   .|| ...      .|  | ||| || ||||  |.     . |   .     ....|.|.|
teesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtq

RPKTIQTRNQVKF
|  .||| .| .|
rafsiqtpeqyef

0049772 (Phosphotyrosine protein) phosphatases II 129-238 1.5e-25 86.0 In-house 169-277 (314) alignment
Range on Protein: 129-238
Range on HMM: 169-277/314.0
FSYSFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASViQEGGKIAVHCHAGRGRTG-LIIAAYLIFHNDYTAAKAIRLVRSQRPkTIQTRNQVKFL
  |. | |...|...... . |.. |. |  ....... .. ..||...|||.||.|||| ...||||. ........|.. ||..||     ......|
elydpelferlgikylripvpDgsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.inpnpgfieql

EEFDMYLHPRR
|.. ..|. ..
eqyefileall

subfamily_PTPMT1_pd Subfamily PTPMT1 129-234 5.4e-19 63.3 In-house 62-168 (171) alignment
Range on Protein: 129-234
Range on HMM: 62-168/171.0
FSYSFESFQQQGVTVCNCAWVDFG-SPPMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFL
.. | |.....||.  . | |||  .| .|. .. |... .|...| .. |||.|||||.. ..|.||. ..  .  .|.. ....|...   ..|.| |
lansteewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkal

EEFDMYL
.|.   |
qeyeekl

subfamily_PRL_pd Subfamily PRL 129-231 3.6e-14 47.1 In-house 44-146 (151) alignment
Range on Protein: 129-231
Range on HMM: 44-146/151.0
FSYSFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASVIQEGG--KIAVHCHAGRGRTGLIIAAYLIfHNDYTAAKAIRLVRSQRPKTIQTrNQVKF
 .|. |.....|..| . |. | ..|| |   . .... .  .| .   .|||| || ||. ...|  ||  .  .  .|....|..|  .| . .|.||
ptydteklekegievldlafddGavPpeevveeWlellkekfkeepkstvavhcvaGlGraPvlvalali.eaGmkyedavefirekrrgains.kqlkf

LEEFD
||.. 
lekyk

subfamily_CDKN3_pd Subfamily CDKN3 132-231 9.2e-12 38.9 In-house 91-192 (202) alignment
Range on Protein: 132-231
Range on HMM: 91-192/202.0
SFESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAA-KAIRLVRSQR-PKTIQTRNQVKFLEE
 .. .|| |..|      | . | .   |.|.. .   .... |  |||. | ||. |.||  |.. .|.    .||  .|  .  ..|||  |  .|.|
lldlyqqaglivhhypiadglvpdiasclkileelrinlkayrktlvhcygglgrsslviaclllylddtiepkdaidklrdlkgsraiqtvkqynylse

FD
| 
fr

0051299 (Phosphotyrosine protein) phosphatases II 133-227 4.9e-20 67.6 In-house 177-278 (288) alignment
Range on Protein: 133-227
Range on HMM: 177-278/288.0
FESFQQQGVTVCNCAWVDFGSPP-MERALDIVKIMASVIQE-GGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTIQTRNQVK
.... ..    .  .| |.| |. .|  ||..... ....  || ..|||.|| |||| .||..|.     ...  .. .|.. .|.|||  .|| .| .
gdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyr

FL
|.
fv

CDKN3 Cyclin-dependent kinase inhibitor 3 (CDKN3) 133-202 1.6e-07 22.6 Pfam-A 93-162 (168) alignment
Range on Protein: 133-202
Range on HMM: 93-162/168.0
FESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYT
.. .|| |.        | |.| .  .|.|.. .|.....  |  .||. | ||. |. |. |..  |  
ldlyqqygivthhhpiadggtpdiascleimeelatclknyrktlihcygglgrsclvaaclllylsdsi

CDKN3 Cyclin-dependent kinase inhibitor 3 (CDKN3) 133-202 1.6e-07 22.6 In-house 93-162 (168) alignment
Range on Protein: 133-202
Range on HMM: 93-162/168.0
FESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYT
.. .|| |.        | |.| .  .|.|.. .|.....  |  .||. | ||. |. |. |..  |  
ldlyqqygivthhhpiadggtpdiascleimeelatclknyrktlihcygglgrsclvaaclllylsdsi

subfamily_Auxilin_pd Subfamily Auxilin 134-228 1.3e-07 24.5 In-house 61-158 (166) alignment
Range on Protein: 134-228
Range on HMM: 61-158/166.0
ESFQQQGVTVCNCAWVDFGSPPMERALDIVKIMASVIQEGGK--IAVHCHAGRGRTGLIIAAYLIFHNDYT-AAKAIRLVRSQRPKTIQTRNQVKFLE
.  ..  . | ...|     |..|  ... . . | ...  |  . |||  ||  ......|.|.| . .. . .|.||.  .|  .  .  . ..||
yrtaklssrvveagwparraPnLeslvevcrnlyswlkkdpknvvvvhckDGraasavlvsallvfcrllsepesavrlfsvkrlpiglspsekryle

subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 135-222 4.8e-08 26.6 In-house 47-134 (148) alignment
Range on Protein: 135-222
Range on HMM: 47-134/148.0
SFQQQGVTVCNCAWVDFGSPPMERAL-DIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKtIQTRN
 ..|.|.   ..|  |     .     ||.. .  . .||... ||.. |. |   .  ..|| ... .  .|. ||.|.|.  .. ..
aldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrvslkealalvkskrry.vdpnl

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 137-235 2.3e-06 21.7 In-house 171-278 (315) alignment
Range on Protein: 137-235
Range on HMM: 171-278/315.0
QQQGVTVCN-CAWVDFGSPPMERAL-DIV-KIMASVIQEGGKIAVHCHAGRGRTGLIIAAYL-IFHNDYTA----AKAIRLVRSQRPKTIQTRNQVKFLE
... ||  .   | | |..    .|  .. .. |.  ..   . ||| || ||||..|..   . .   |      . .. .|..||. .||...  |. 
esrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiy

E-FDMYLH
.    .|.
davledll

0047943 (Phosphotyrosine protein) phosphatases II 140-228 7.4e-22 73.5 In-house 168-265 (273) alignment
Range on Protein: 140-228
Range on HMM: 168-265/273.0
GVTVCNCAWVDFGSP-PMERALDIVKIMASVIQ---EGGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLE
   ..   | |.| |  .|  |...... ....   ..|...|||.|| |||| .||..|.      ..  .. .|..|.|||||  .|| .| .|| 
vthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrfly

subfamily_DSP23_pd Subfamily DSP23 140-234 3.9e-17 57.3 In-house 51-145 (148) alignment
Range on Protein: 140-234
Range on HMM: 51-145/148.0
GVTVCNCAWVDFGSPPMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
..|. .    |.  | .|.  ..|...    . .  ..|||  |||||| ..| ||. ... .||.||  || .|| ...| .| | . ... ..
nltlvrlriddyhppaleqvvefvrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgsvetveqeklvrdyetfi

0050432 (Phosphotyrosine protein) phosphatases II 144-227 6.4e-21 70.4 In-house 189-291 (308) alignment
Range on Protein: 144-227
Range on HMM: 189-291/308.0
CN--------------CAWVDFGSPP-MERALDIVKIMASVIqEGGKIAVHCHAGRGRTGLIIAAYLI-----FHNDYTAAKAIRLVRSQRPKTIQTRNQ
.|               .| |.| || .|  ||..... ... .||.|.|||.|| |||| .||..|.      ..  .. .|.. .|.|||  .|| .|
tnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl.pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeq

VKFL
 .||
ylfl

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 145-227 1.2e-06 23.0 In-house 192-282 (298) alignment
Range on Protein: 145-227
Range on HMM: 192-282/298.0
NCAWVDFGSPPMERA-LDIVKIMASVIQEGG--KIAVHCHAGRGRTGLIIAAYLIFHNDYT-----AAKAIRLVRSQRPKTIQTRNQVKFL
   | | | | .... ||... .    |. |   . |.| || ||.|  || . ..    .       .... .| .||...||..| .|.
ftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfi

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 145-228 1.9e-06 22.3 In-house 144-235 (250) alignment
Range on Protein: 145-228
Range on HMM: 144-235/250.0
NCAWVDFGSPPMERA-LDIVK-IMASVIQ-EGGKIAVHCHAGRGRTGLIIAAYLIFHNDYT-----AAKAIRLVRSQRPKTIQTRNQVKFLE
  .| | | | . .| |...| . ||  | . . . |.| || ||.|  || . ....  .       | |. .| .||.......|  |. 
fvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvy

subfamily_Cele-PTP-7_pd Subfamily Cele-PTP-7 145-227 3.4e-06 20.7 In-house 195-280 (302) alignment
Range on Protein: 145-227
Range on HMM: 195-280/302.0
NCAWVDFGSPP-MERALDIVKIMASVIQeggKIAVHCHAGRGRTGLIIAA-YLIF---HNDYT-AAKAIRLVRSQRPKTIQTRNQVKFL
 .|| | |.|   . ||||.|   |  .   .. ||| || |||| ..|  | |    ... |  .. .  ||. |  ..|. .|. .|
fsawpdhGapkeaytaldilkfcesykk...nvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliyl

subfamily_PTPN13_pd Subfamily PTPN13 146-227 3.4e-10 34.6 In-house 174-261 (273) alignment
Range on Protein: 146-227
Range on HMM: 174-261/273.0
CAWVDFGSPPME-RALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIF-----HNDYTAAKAIRLVRSQRPKTIQTRNQVKFL
 .| | | |      | .|. .... .. | |.||| || ||.| .|. . ..      ...   . .| .| ||   .||..|  | 
vkwPdhgvPssaaellqfvaevrrlqtdagPivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifv

subfamily_PTPRB_pd Subfamily PTPRB 146-229 1.8e-09 32.0 In-house 187-279 (293) alignment
Range on Protein: 146-229
Range on HMM: 187-279/293.0
CAWVDFGSPPME-RALDIVKIMASVI---QEGGKIAVHCHAGRGRTGLIIAAYLIF----HNDYTA-AKAIRLVRSQRPKTIQTRNQVKFLEE
 .|.|.| |      ||.|. . ..|   .. . | ||| || ||||  ||   ..    ..||   .  .  .|..|   .|| .|  |...
tsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihq

subfamily_PTPN12_pd Subfamily PTPN12 146-227 1.3e-08 29.1 In-house 178-269 (290) alignment
Range on Protein: 146-227
Range on HMM: 178-269/290.0
CAWVDFGSPPM-ERALDIVKIMASVIQ-EGGKIAVHCHAGRGRTGLIIAAYLIFHN--------DYTAAKAIRLVRSQRPKTIQTRNQVKFL
 || | | |   .. |.... . .. . |   ..||| || |||| |||  .. .         ..   . .. .| ||.  .||..| ...
taWPDhgvPssaksllelielvrelqesedaPlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelv

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 146-232 2.5e-08 28.3 In-house 183-276 (288) alignment
Range on Protein: 146-232
Range on HMM: 183-276/288.0
CAWVDFGSPPMERA-LDIVKIMASVIQEG-GKIAVHCHAGRGRTGLIIAAYLIFH----NDYT-AAKAIRLVRSQRPKTIQTRNQVKFLEEFDM
 ||.| | |  ..  |......    |.  |.| ||| || ||||  ||.  . .    .||   | ..  .| ||.  .|| .|  |. |  .
laWpdhgvPeskapllellrqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevll

subfamily_PTPN3_pd Subfamily PTPN3 146-229 2e-07 25.3 In-house 179-269 (280) alignment
Range on Protein: 146-229
Range on HMM: 179-269/280.0
CAWVDFGSPPME-RALDIVKIMASVI-QEGGKIAVHCHAGRGRTGLIIAAYLIFH-----NDYTAAKAIRLVRSQRPKTIQTRNQVKFLEE
 || | | |  .   |..|. . ..   .   . ||| || ||||..|.  . ..     ..    . .| .| ||   .|| .| ||. |
laWpdhgvPddsadflefvervrklrsgkeePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCe

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 146-227 3.7e-07 24.5 In-house 183-272 (318) alignment
Range on Protein: 146-227
Range on HMM: 183-272/318.0
CAWVDFGSPPME-RALDIVKIMASVI--QEGGKIAVHCHAGRGRTGLIIAAYLIFHNDY---T--AAKAIRLVRSQRPKTIQTRNQVKFL
 .| | |.|      ||.|.   ..   .. | |.||| || ||||  ||   . .      .    . .. .|.||.  .||..| .|.
tsWpdegvpesgaslldlvrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefi

subfamily_PTPRN_pd Subfamily PTPRN 146-227 5.7e-06 20.2 In-house 195-284 (297) alignment
Range on Protein: 146-227
Range on HMM: 195-284/297.0
CAWVDFGSPPMERAL-DI-VKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIR------LVRSQRPKTIQTRNQVKFL
 .| . | |.  ..| .   |.  |       | ||| .| ||||  |.  |. ..    .| |        .| |||. ..|..| .| 
lswpeegvPasaksllefrrkvnksyrGrscpivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefa

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 146-227 7.5e-06 19.8 In-house 196-281 (305) alignment
Range on Protein: 146-227
Range on HMM: 196-281/305.0
CAWVDFGSPPMEraLDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHN----DYT--AAKAIRLVRSQRPKTIQTRNQVKFL
. | | | ||    |  .......      | ||| || |||| |.|   |. .           . .. .| ||  .||.  |  |.
tewpdrgvppck..ltslellsairgskvpivvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfi

0048567 (Phosphotyrosine protein) phosphatases II 147-234 1.5e-16 55.1 In-house 44-138 (157) alignment
Range on Protein: 147-234
Range on HMM: 44-138/157.0
AWVDFGSPPMERALDIVKIMASVIQ----EGGKIAVHCHAGR---GRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
 . ||| ... .  . .... ....    .|..|||||.||.   |||...|..||| |...|...||...|  ||. .  | .  .|  ....|
fffdfGPlnlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslynltl

PTPc_DSPc_SM00012 147-227 1.4e-13 46.3 In-house 9-99 (105) alignment
Range on Protein: 147-227
Range on HMM: 9-99/105.0
AWVDFGSPP-MERALDIVKIMASVIQE---GGKIAVHCHAGRGRTGLIIAAYLIFHNDYTA------AKAIRLVRSQRPKTIQTRNQVKFL
.| |.| |  ..  |.... . .. ..   .. . |||.|| |||| ..|.... .. ..        . .. .|.|||...|| .|. ||
gwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylfl

Y_phosphatase Protein-tyrosine phosphatase 147-227 2.5e-11 38.8 Pfam-A 142-229 (235) alignment
Range on Protein: 147-227
Range on HMM: 142-229/235.0
AWVDFGSPpmERALDIVKIMASVIQEG----GKIAVHCHAGRGRTGLIIAAYLIFHNDYT-----AAKAIRLVRSQRPKTIQTRNQVKFL
.| | | |  | . ...... .| ..     |.. ||| || |||| ..|. .....  .       .... .|.|||. .|. .| .||
nWpdhgvp..espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYifl

Y_phosphatase Protein-tyrosine phosphatase 147-227 2.5e-11 38.8 In-house 142-229 (235) alignment
Range on Protein: 147-227
Range on HMM: 142-229/235.0
AWVDFGSPpmERALDIVKIMASVIQEG----GKIAVHCHAGRGRTGLIIAAYLIFHNDYT-----AAKAIRLVRSQRPKTIQTRNQVKFL
.| | | |  | . ...... .| ..     |.. ||| || |||| ..|. .....  .       .... .|.|||. .|. .| .||
nWpdhgvp..espkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYifl

subfamily_PTPRA_pd Subfamily PTPRA 147-227 1.7e-09 32.1 In-house 200-287 (330) alignment
Range on Protein: 147-227
Range on HMM: 200-287/330.0
AWVDFGSPPMERA-LDIVK-IMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYT-----AAKAIRLVRSQRPKTIQTRNQVKFL
.| |.| |   .  |...| . .   |..| | ||| || ||||  |.   ...   .       .... .| |||. .|| .| .|.
swPdvGvPfepiGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefi

subfamily_PTPRK_pd Subfamily PTPRK 147-229 1.7e-08 28.7 In-house 182-271 (314) alignment
Range on Protein: 147-229
Range on HMM: 182-271/314.0
AWVDFGSPPMERAL-DIV-KIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFH-----NDYTAAKAIRLVRSQRPKTIQTRNQVKFLEE
.| |.. |  ...| ..| .. .|  .| |.| ||| || ||||  ||   .       .     .|.. .||...  ..| .| ||. .
gWpdhdvPvsatgllklvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiyd

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 147-227 6.3e-08 27.0 In-house 185-269 (307) alignment
Range on Protein: 147-227
Range on HMM: 185-269/307.0
AWVDFGSPPMEraLDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFH------NDYTAAKAIRLVRSQRPKTIQTRNQVKFL
 | | | |...  |  . .. .|  .   . ||| || ||.| |.|  |.        |     | .. .||||. .|||  |  .|
nwpdrgvpqin..ltainlleavrydtnpvvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylyl

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 147-231 1.3e-07 25.6 In-house 195-283 (305) alignment
Range on Protein: 147-231
Range on HMM: 195-283/305.0
AWVDFGSPPMERAldIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHND------YTAAKAIRLVRSQRPKTIQTRNQVKFLEEFD
 | | | |. . |  |.....      | |.||| || |||| ..    |...         . | .. .| || ..||| .|  |. .  
dwpdrgvpaadla..ilellekarpskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvi

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 147-227 2.9e-07 24.0 In-house 181-268 (515) alignment
Range on Protein: 147-227
Range on HMM: 181-268/515.0
AWVDFGSPPMERAL-D-IVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAY-LIFHNDYTAA----KAIRLVRSQRPKTIQTRNQVKFL
 | | |.|.  ..|   | .. |.  |    . .|| || ||||..|..   . |   | .    . .. .| .||. .||..|  |.
eWPdkGvpkhtssllklikevkadhgqythpliihcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafi

subfamily_PTPRG_pd Subfamily PTPRG 147-228 4.3e-07 23.5 In-house 192-280 (563) alignment
Range on Protein: 147-228
Range on HMM: 192-280/563.0
AWVDFGSPPMER-ALD-IVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIF-----HNDYTAAKAIRLVRSQRPKTIQTRNQVKFLE
 | | |.|  .   |  ..|  |.  .| | | |||.|| ||||  |.   .      .|     . .. .|.||.  .||..|  || 
kWPdhgvPehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflh

subfamily_RNGTT_pd Subfamily RNGTT 148-224 6e-11 36.4 In-house 85-164 (189) alignment
Range on Protein: 148-224
Range on HMM: 85-164/189.0
WVDFGS-PPMERALDIVKIMASVIQE--GGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQV
    |  |  |.   . |.. . ...     |.|||. |  ||| .|..||. ..|. . .|..| .. ||. |   . .
cagkgeaPeaeqvkefiklveeffkknpeevigvhCthGfnRtGFlivsyLvekedwsveaavalFakaRppGiykedyl

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 148-228 3.2e-07 24.6 In-house 162-257 (270) alignment
Range on Protein: 148-228
Range on HMM: 162-257/270.0
WVDFGSPPMER----ALDIVKIMASV------IQEGGKIAVHCHAGRGRTGLIIAAYLIF-----HNDYTAAKAIRLVRSQRPKTIQTRNQVKFLE
| | | |..|     . ...|... |       .... . ||| || ||||..||   ..     ..    .. |. .| .|.. .|. .|..|| 
WpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyefly

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 148-229 9e-07 23.2 In-house 188-277 (319) alignment
Range on Protein: 148-229
Range on HMM: 188-277/319.0
WVDFGSPPMER-ALDIVKIMASVIQ--EGGKIAVHCHAGRGRTGLIIAAYLIFHN-----DYTAAKAIRLVRSQRPKTIQTRNQVKFLEE
| | . |   .  ||..| ..   .  . | | ||| || ||||  |.   .. .          . .. .| ||.  .|. .| ||. |
WpdhdvPekatslldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiye

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 148-227 1.3e-06 22.9 In-house 195-283 (319) alignment
Range on Protein: 148-227
Range on HMM: 195-283/319.0
WVDFGSP----PMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHN-----DYTAAKAIRLVRSQRPKTIQTRNQVKFL
| | | |    .. | .. |. . |  ..  .| ||| || ||||  |.   ...           . .| .| ||.. .|   | ||.
wpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfi

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 148-228 1.4e-06 23.0 In-house 159-248 (284) alignment
Range on Protein: 148-228
Range on HMM: 159-248/284.0
WVDFGSP----PMERALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHN-----DYTAAKAIRLVRSQRPKTIQTRNQVKFLE
| | | |    .. | .. |. . |  ..  .| ||| || ||||  |.   ...           . .| .| ||.. .|   | ||. 
wpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiy

subfamily_PTPRD_pd Subfamily PTPRD 148-227 3e-06 21.2 In-house 187-273 (564) alignment
Range on Protein: 148-227
Range on HMM: 187-273/564.0
WVDFGSPPME-RALDIV-KIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHN-----DYTAAKAIRLVRSQRPKTIQTRNQVKFL
| | | |      ||.. |. |.  .. | | ||| || ||||  |.   .        .    . ....|.||.  .||..|  |.
WPdhgvpesatslLdlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFi

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 159-224 2.8e-06 21.2 In-house 202-272 (290) alignment
Range on Protein: 159-224
Range on HMM: 202-272/290.0
ALDIVKIMASVIQEGGKIAVHCHAGRGRTGLIIAA-----YLIFHNDYTAAKAIRLVRSQRPKTIQTRNQV
.| ..... .. .  | ..||| || |||| ..|       |.   ..  .. .| .|  | ...|   | 
tlallrtlrilrkasGpvvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqy

subfamily_DSP12_pd Subfamily DSP12 162-226 2.6e-09 31.6 In-house 71-135 (155) alignment
Range on Protein: 162-226
Range on HMM: 71-135/155.0
IVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKF
.|. . . ..|.|.. |||.||  |   |..|||. ...    ||..||....|..    . .. 
avdFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlklvkekkpeiepNegFleQ

subfamily_DSP1_pd Subfamily DSP1 162-216 6e-09 30.2 In-house 84-138 (163) alignment
Range on Protein: 162-216
Range on HMM: 84-138/163.0
IVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPK
... . .|....||. .||.||  |   .. |||. .. ..  .|  .|...|. 
viefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleeafdfvkqrRsi

subfamily_DSP14_pd Subfamily DSP14 162-216 1.2e-08 29.1 In-house 72-126 (157) alignment
Range on Protein: 162-216
Range on HMM: 72-126/157.0
IVKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPK
... . .| ..|||. ||| ||. |   .  |||. ..  . ..| .||.|.|| 
vadkieevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreayklvksaRpi

subfamily_MKPLT_pd Subfamily MKPLT 163-231 2.2e-08 27.8 In-house 89-157 (164) alignment
Range on Protein: 163-231
Range on HMM: 89-157/164.0
VKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFD
 | .|. |. ||.. |||  |. |.  .  |.||  . .|  .|   .. .|  .   |  .| | .|.
akfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfe

subfamily_MKPLV_pd Subfamily MKPLV 163-231 2.2e-08 27.8 In-house 89-157 (164) alignment
Range on Protein: 163-231
Range on HMM: 89-157/164.0
VKIMASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFD
 | .|. |. ||.. |||  |. |.  .  |.||  . .|  .|   .. .|  .   |  .| | .|.
akfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeayeylkerrsivapnrGflkqlakfe

subfamily_PTPN6_pd Subfamily PTPN6 164-228 2.1e-08 28.5 In-house 217-290 (306) alignment
Range on Protein: 164-228
Range on HMM: 217-290/306.0
KIMA----SviqEGGKIAVHCHAGRGRTGLIIAAYLI--------FHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLE
. .     .   | | | ||| || |||| .|   ..        .. |.   |....||.||   .|| .| ||. 
rkqeeleea...eagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvy

subfamily_DSP19_pd Subfamily DSP19 166-217 2.1e-09 31.9 In-house 82-133 (152) alignment
Range on Protein: 166-217
Range on HMM: 82-133/152.0
MASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKT
. .. .. | . |||.||. |.  .. |||. ... .  .|..|||..||  
ieearskdgavlvHCnAGvSRsasvviaylmkkeelsleealelvrearpci

subfamily_DSP8_pd Subfamily DSP8 166-220 1.8e-07 24.8 In-house 86-139 (159) alignment
Range on Protein: 166-220
Range on HMM: 86-139/159.0
MASVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRpKTIQT
.  . .| |.. ||..||. |   .. ||.. . . .  .| | |...| .||. 
idkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfvkekr.ptisp

subfamily_DSP10_pd Subfamily DSP10 168-234 8.1e-08 26.3 In-house 87-153 (159) alignment
Range on Protein: 168-234
Range on HMM: 87-153/159.0
SVIQEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
 . ..| .. |||.||  |   .. |||. | . .  .| ..|...||      | .  | ||.  |
earkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekel

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 168-228 7.9e-06 20.2 In-house 206-276 (305) alignment
Range on Protein: 168-228
Range on HMM: 206-276/305.0
SVI----QE-GGKIAVHCHAGRGRTGLIIAAYLIFHN-----DYTAAKAIRLVRSQRPKTIQTRNQVKFLE
 |     .. |  . ||| || ||||  ||  . .           .. .. .||.|.| .|| .|  || 
rvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflh

subfamily_DSP11_pd Subfamily DSP11 171-229 4.1e-08 27.3 In-house 114-172 (178) alignment
Range on Protein: 171-229
Range on HMM: 114-172/178.0
QEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEE
...  |.|||  |  ||| .|  ||| ...| . .||.   . |  ...  | .| |..
dndkligvhCthGvnrtGyliCrylidvegyepedaieafeearGhslerenylkdLkk

subfamily_LRR-DSP_pd Subfamily LRR-DSP 171-229 3.7e-06 20.2 In-house 192-253 (263) alignment
Range on Protein: 171-229
Range on HMM: 192-253/263.0
Q---EGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEE
.   . | . ||| ||  |.  .. .||. ..  .  .|. || ..||.    .  .. |  
eeGrkkGGvlvhcraGvsrsstlvisylmkkqrlkfkealdlvikkrpriqPnpGfkdqlkk

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 171-229 8.4e-06 19.4 In-house 125-188 (440) alignment
Range on Protein: 171-229
Range on HMM: 125-188/440.0
QEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAA-----KAIRLVRSQRPKTIQTRNQVKFLEE
   | . ||| || ||||.|||   |...   .        |  .|..||. .|| .|  |. |
agngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqyafvhe

subfamily_DSP6_pd Subfamily DSP6 171-234 9.7e-06 19.2 In-house 91-154 (158) alignment
Range on Protein: 171-234
Range on HMM: 91-154/158.0
QEGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTAAKAIRLVRSQRPKTIQTRNQVKFLEEFDMYL
..  |. |||.||  |.  .. |||. .. ..  .|  ||......     | .. | .|.  |
skkskvlvhClaGisrsvtvtlaylmkklalslndaydlvkkrksnisPnfnfmgqlldfersl

subfamily_CG42327_pd Subfamily CG42327 172-227 1.1e-06 22.6 In-house 246-307 (319) alignment
Range on Protein: 172-227
Range on HMM: 246-307/319.0
EGGKIAVHCHAGRGRTGLIIAAYLIFHNDYTA------AKAIRLVRSQRPKTIQTRNQVKFL
. | ..|||  | |||||.||. . ...  ..       . .  || .| ....|..| .|.
sqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefi

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 174-230 6.1e-08 26.9 In-house 229-290 (297) alignment
Range on Protein: 174-230
Range on HMM: 229-290/297.0
GKIAVHCHAGRGRTGLIIAAYLIFHN---DY--TAAKAIRLVRSQRPKTIQTRNQVKFLEEF
  . ||| || ||.|... .  |      ..   .|  .. .|.||....|| .| ..| ..
ayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda

subfamily_PTPN14_pd Subfamily PTPN14 174-227 1.6e-06 22.4 In-house 230-288 (300) alignment
Range on Protein: 174-227
Range on HMM: 230-288/300.0
GKIAVHCHAGRGRTGLIIAAYLIF----HND-YTAAKAIRLVRSQRPKTIQTRNQVKFL
  . ||| || |||| .| . |.     ||.     |... .| ||   .||  | ||.
PPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfv