Gene MTMR10-1 in Amphimedon queenslandica

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family Myotubularin
Subfamily MTMR10
Protein sequence
ID Type Fasta BLAST phosphatome Note
AqueP026_AA protein Get Run
AqueP026_AA_65-160 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_MTMR10_pd Subfamily MTMR10 37-155 1e-28 92.2 In-house 174-305 (380) alignment
Range on Protein: 37-155
Range on HMM: 174-305/380.0
FAFDYARVVHKTKDTHSSSSSSSQDVI------------PTYFNPRDWQKELDRLGVNQKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLE-YAAGLH
.|.|....|...|.......|...|..            |.|.. ...|..... .|..............  ..|..|.........|..|| ... ..
tasdavktvvekkrsvilqesegrDlscvvaSLaqlmldphyrtisGfqsliqkewvaaghpfldrlghikpseksespvfllFldcvdqlleqfpseFe

FKNRLPVWCWSHSVIGVSLTRGSLPDEDRLEA
|........|..|..|. ||. .  .| ||.|
FtetfLialwdsshsgifltflfnseeqrlka

Myotubularin-like phosphatase domain 36-148 7.1e-24 77.2 Pfam-A 2-103 (353) alignment
Myotubularin-like phosphatase domain 36-148 7.1e-24 77.2 In-house 2-103 (353) alignment
0040695 (Phosphotyrosine protein) phosphatases II 65-148 2.8e-22 73.0 In-house 6-89 (388) alignment
Range on Protein: 65-148
Range on HMM: 6-89/388.0
TYFNPRDWQKELDRLGVNQKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLP
 . . .|. .|| |||.. . ||..  |... ||.|.|...|||. |||..|...|    |.|.||....|.  | .|.| | |
egwslydilrelkrlglgldlwrisivNenyelcpsYPallvVPksisdellkrvarfrskgriPvlsyrhpnngavllRssqp

subfamily_Dicty-MTMR1-like_pd Subfamily Dicty-MTMR1-like 70-148 5e-19 60.7 In-house 19-98 (404) alignment
Range on Protein: 70-148
Range on HMM: 19-98/404.0
RDWQKELDRLGVNQK-QWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLP
 | ..|  |||.... .||....|... ||.. | ..||| .|||. |. .|    |.|.|| .| |   ....|| | |
ydaeeEykRlgikseseWriskinsdyelcetYPkllvvPesisDeelkkvasfRskgRiPvlswrhrsknstitRssqp

subfamily_MTMR1_pd Subfamily MTMR1 71-148 5.7e-17 54.1 In-house 11-89 (389) alignment
Range on Protein: 71-148
Range on HMM: 11-89/389.0
DWQKELDRLGVNQK-QWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLP
| ..||.|||. .. .||.|. |... |||. |. .||| ..||..|. .| .. |.|||| .| .   . ...| | |
dpeaelerlgllneklWritklnkkyelcdtYpavlvvpkvvsdedlkkvaafrskgRlPvlswlnkenqavilrasqp

subfamily_MTMR5_pd Subfamily MTMR5 73-147 1.1e-16 52.7 In-house 11-92 (483) alignment
Range on Protein: 73-147
Range on HMM: 11-92/483.0
QKELDRLGVN-------QKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSL
 .. .|||..       ....|..|.|... .|.| |  |||| ..|||...  |  . .||||| .| |.  .  | |.. 
vqdykRlGlgalngaskrgkfrisevNkkytvcrsYPalivvPsevsddsiarvakcfrqnRlPvvtWrhernkalLiRsgg

subfamily_MTMR3_pd Subfamily MTMR3 68-149 1.3e-16 53.4 In-house 25-107 (442) alignment
Range on Protein: 68-149
Range on HMM: 25-107/442.0
NPRDWQKELDRLGVN-QKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLPD
   . ..|..||| . ...||....|..| || | |  ..||  |.||.|. .|     .|||.  | |   |  |.| | |.
aeeklkeeverlGfdlkeawrisdvnsdfklCssyPkklivPksitdddlkkvasfrslkrlPavvwrhkkngavlarcsqPe

subfamily_MTMR9_pd Subfamily MTMR9 65-148 2.8e-15 48.3 In-house 13-96 (393) alignment
Range on Protein: 65-148
Range on HMM: 13-96/393.0
TYFNPRDWQKELDRLGVNQKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLP
. ..  | ..|. .| . ...||... |..| .| | |. ..|| .|.|..|.  |    . |.|| .. |.  .  | | | |
dgysafdrenefaklisasdewRissvNknfkvcasypesvivPkaiddeelkasaafreggrfPvLsylhketkavllrssqp

subfamily_MTMR6_pd Subfamily MTMR6 67-148 2.6e-12 38.7 In-house 19-100 (397) alignment
Range on Protein: 67-148
Range on HMM: 19-100/397.0
FNPRDWQKELDRLGVNQKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLP
..  |...|. |.|| ...| .|..|... |||. |  ..|| ... ..|  .. .  |.||||  . |     .. | | |
wklldlkaeytrmgvpnekwtltdlnkdyelcdtyprelyvPksatkevlvgsskfrskgrlPvlsylhkeneaaicrcsqp

subfamily_pats1_pd Subfamily pats1 74-138 1.1e-08 26.0 In-house 13-76 (691) alignment
Range on Protein: 74-138
Range on HMM: 13-76/691.0
KELDRLGVNQKQ-WRVTEANQHFlLCDSLPPYIVVPYNISDDTLEYAAgLHFKNRLPVWCWSHSVI
.| .||...  . |||.|  ..  |..  |. |.||  .||. |   .  . . ..|| .||.   
iegqrlkldldkdwrvveflsrd.lseiyPkrilvPklvsdellvsyv.rkrsskiPvlswsnqnn

subfamily_Ank-MTMR1_pd Subfamily Ank-MTMR1 82-148 2.3e-07 21.9 In-house 38-104 (405) alignment
Range on Protein: 82-148
Range on HMM: 38-104/405.0
NQKQWRVTEANQHFLLCDSLPPYIVVPYNISDDTLEYAAGLHFKNRLPVWCWSHSVIGVSLTRGSLP
..  |.||. |... .| | .  .||  .  |  ||    .. | |.|   |       |..| | |
sncywkvtsinkeykmcssyssslvvlskaldkdlekifsfrskgripslswkdpssnasisrcsqp