Gene DDB_G0269404 in Dictyostelium discoideum

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP19
Protein sequence
ID Type Fasta BLAST phosphatome Note
DdisP013_AA protein Get Run
DdisP013_AA_29-171 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP19_pd Subfamily DSP19 20-168 2e-61 200.8 In-house 2-151 (152) alignment 
Range on Protein: 20-168
Range on HMM: 2-151/152.0
MVEDLEEEIcfDAQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKI--KEFTTLCINIEDESQKDISSYFQQCHGFIENGRKL-GGILVHCSAG
.||||.|..  ...||.|.||.||...|.....|||.||||||...|. |..  |.||.|.|.| |....|..||......|||..|.  | .||||.||
fveDlkedl..evgeveprlylgsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAG

VSRSASVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATIL
|||||||||.|||.   . ........|..||||.||.|||.|| .|||..|
vSRsasvviaylmkkeelsleealelvrearpcikPneGFikqLkeyeaell
subfamily_LRR-DSP_pd Subfamily LRR-DSP 32-169 5e-40 131.2 In-house 120-260 (263) alignment 
Range on Protein: 32-169
Range on HMM: 120-260/263.0
AQEVIPNLYIGSISAATCTTSLKEHKITHI-LSISTNPP-KIKEFTTLCI-NIEDESQKDISSYFQQCHGFIENGRKLGGILVHCSAGVSRSASVVISYL
 .|.|..|..|.  .|.  . ||.  .||| |...   |   | |  | | .|||  . ||| .|..   |||.||| ||.|||| ||||||...|||||
PdeiidklflGgldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeGrkkGGvlvhcraGvsrsstlvisyl

MSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
|      |   .    . || ||||.||..||  ||. . .
mkkqrlkfkealdlvikkrpriqPnpGfkdqlkkyekklfc
subfamily_DSP15_pd Subfamily DSP15 33-171 5.3e-37 121.2 In-house 3-143 (151) alignment 
Range on Protein: 33-171
Range on HMM: 3-143/151.0
QEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPK-IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRK-LGGILVHCSAGVSRSASVVISYLMS
..|.|.||.| .  .  .. |||..||||||.. |. | .|... .||...| .....|..|...  || . |   ...|||| ||||||. .|. |||.
skvlpglylgnfrdskdeelLkeknithilsvhdnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmt

VFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQ
|    .  ... ... | . .||.|| .|| .|| | ||. 
vtelnwrdalevikaaRsvanPnfGfkrqlkeyektklkey
subfamily_DSP12_pd Subfamily DSP12 32-169 2.3e-36 119.5 In-house 2-145 (155) alignment 
Range on Protein: 32-169
Range on HMM: 2-145/155.0
AQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNP-----PKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGR-KLGGILVHCSAGVSRSASVVI
.... |.||.|...|.. ...||| ||||.||. ...     .|... .|. |.| || ..|| |.....  |||... . | .|||| ||||||...||
vsrilpglylggleavqeeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtivi

SYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
 |||     ..   .. .....| |.||.||..||  .|.   |
AYlmkkeklslekAlklvkekkpeiepNegFleQLklfekmgck
subfamily_DSP1_pd Subfamily DSP1 23-170 3.4e-35 115.5 In-house 8-159 (163) alignment 
Range on Protein: 23-170
Range on HMM: 8-159/163.0
DLEEEICFDAQE-VIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKI--KEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVS
||..   .|  | ... ||.|| . |. .  ||...||.|| .|.. ...  . |.  ....||....|||..|..   ||.. .| .| .|.|| ||.|
dldklklydPvekildfLylGsetvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGis

RSASVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKN
||..... |||.     .   ... .. |..|.||.||..||.||| ..|..
RsstlclaylmktkrvsleeafdfvkqrRsiisPnagFvlqLlnyekkllle
PTPc_motif_SM00404 32-165 4e-35 115.7 In-house 2-139 (140) alignment 
Range on Protein: 32-165
Range on HMM: 2-139/140.0
AQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPP---KIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISY
 ... |.||.||.|.|.    ||...|||....... .   . ..|. |.|...|. ....| |....  |||| .| || .|||| |||||||...| |
psrilphlylgskskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaY

LMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEA
||.        ....... ||.|.||..|..|||.|| 
lmryrqlslaeayefvkerRpiispnlnfvrqLieyek
0044763 (Phosphotyrosine protein) phosphatases II 19-172 4.5e-35 116.3 In-house 10-175 (178) alignment 
Range on Protein: 19-172
Range on HMM: 10-175/178.0
DMVEDLEEEICFDAQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPK--IKE---------FTTLCINIEDESQKDISSYFQQCHGFIENG--RK
...|.||   ...| |..|.||.||  .|     |||..||||...... .   .|.         .. |.|.|.| .  |....|.... |||.   .|
snleglersdyinaseilpglylgslppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdek

LGGILVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRPcIQPNTGFINQLINYEATILKNQN
 | .||||||||.||...|. ||| ..  ..  .....|. || |.|| |...||. .|  .||...
ggpvlVHCsaGvgRsgtlvaaylmkklglsleeaielvrerRp.ivpnpgqlrqLyefelrllkesd
subfamily_DSP10_pd Subfamily DSP10 31-171 4.2e-34 111.7 In-house 13-157 (159) alignment 
Range on Protein: 31-171
Range on HMM: 13-157/159.0
DAQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKIKEF---TTLCINIEDESQKDISSYFQQCHGFIENGRKLG-GILVHCSAGVSRSASVVIS
.| .|.| |..||   |. ...|....||..| . |. |.  |    .   |...| |..... ||..   |||. || |  .|||| ||.||||.|||.
pasqvlpfLflGsekdaadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvvia

YLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQ
|||  .   .    .. .. || | || .|. ||...| .. |..
YlmkhlnlslndaykfvkekrpiisPnLnfmGqLlefekelnksk
subfamily_DSP14_pd Subfamily DSP14 33-173 1.6e-33 109.9 In-house 8-150 (157) alignment 
Range on Protein: 33-173
Range on HMM: 8-150/157.0
QEVIPNLYIGsISAATCTTSLKEHKITHILSISTNP--PKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLG-GILVHCSAGVSRSASVVISYLM
 .. |.|...  .||.  . ||..|||.|. ....   .|.|.. .. . .||.........|..    ||. .| |  .|||| ||||||||... |||
sqitpsLfls.gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylm

SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQNV
    .      ......|| |.||.|| .|||.||  . ... |
kyeklsLreayklvksaRpiirPNvGFwkqlidyEkklkgkssv
DSPc Dual specificity phosphatase, catalytic domain 39-165 1.7e-31 103.9 Pfam-A 1-132 (133) alignment 
Range on Protein: 39-165
Range on HMM: 1-132/133.0
LYIGSISAATcTTSLKEHKITHILSISTNPPK-----IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISYLMSVF
||.|| |.|.  . |....||........ |.      .|.. |.| .|||....||......  |||. .. |. .|||| ||.||||...| |||. .
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

FKPFWYCMQYLRNIRPCIQPNTGFINQLINYEA
  .   ....... |..| ||.||. ||..|| 
nlslneAyefvkerrskispnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 39-165 1.7e-31 103.9 In-house 1-132 (133) alignment 
Range on Protein: 39-165
Range on HMM: 1-132/133.0
LYIGSISAATcTTSLKEHKITHILSISTNPPK-----IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISYLMSVF
||.|| |.|.  . |....||........ |.      .|.. |.| .|||....||......  |||. .. |. .|||| ||.||||...| |||. .
lylgskstas.lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktk

FKPFWYCMQYLRNIRPCIQPNTGFINQLINYEA
  .   ....... |..| ||.||. ||..|| 
nlslneAyefvkerrskispnagflrqLleyer
0048076 (Phosphotyrosine protein) phosphatases II 33-166 1.4e-29 98.0 In-house 5-141 (145) alignment 
Range on Protein: 33-166
Range on HMM: 5-141/145.0
QEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKIK--EFTTLCINIEDESQKDISSYFQQCHGFIENGRKLG-GILVHCSAGVSRSASVVISYLM
.|..|.||.||. .|     ||...||..|.......  .   .. |.....| .  |........  |||. .| |  .||||||||.|....|. |||
seilpglylgslptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylm

SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEAT
  .  ..  .....|. ||.. || |....|. .|  
lllgvsleealelvrsqrpgavpnpgqlrflyefele
subfamily_STYX_pd Subfamily STYX 30-172 7.2e-29 94.0 In-house 10-162 (166) alignment 
Range on Protein: 30-172
Range on HMM: 10-162/166.0
FDAQEVIPNLYIGSISAATCT--TSLKEHKITHILSISTNP-------PKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSR
 . ||..| |..|  |||  .    ||.| ||||. |  |.          ..|  | ... |.. ..|  |. . ..||..  . || .|||  ||.||
remqeilpglflgpysaamksklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisr

SASVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQN
||..||.|.|  .   .  ...|... | ||.|| ||..|| .|||  | . .
saalviayimetyglkyreafayvqerrfcinpnegfvsqlkeyeaiylaklt
0048179 (Phosphotyrosine protein) phosphatases II 34-165 7.5e-29 95.7 In-house 6-142 (144) alignment 
Range on Protein: 34-165
Range on HMM: 6-142/144.0
EVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKI----KEFTTLCINIEDESQKDISSYFQQCHGFIENGRKL-GGILVHCSAGVSRSASVVISYL
|..|.||.||. .|     ||...||........ ..       .. |.....| .  |........  |||. ..  | .||||||||.|....|. ||
eilpglylgslptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaayl

MSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEA
| ..  ..  .....|..||.. || |....|..|| 
mkklglsleealalvrsrrpgavpnpgqlrfLleyek
subfamily_DSP6_pd Subfamily DSP6 33-167 9.6e-29 93.9 In-house 15-154 (158) alignment 
Range on Protein: 33-167
Range on HMM: 15-154/158.0
QEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPK----IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKL-GGILVHCSAGVSRSASVVISY
 |..|.||.||  .|. . .||..|| ..| . .| |.     .|.. | | |||. .......| .   ||...|.   ..|||| ||.|||  |...|
veilpllylGsakdasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlay

LMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATI
||.     .    ..... .. | ||  |..||...| ..
lmkklalslndaydlvkkrksnisPnfnfmgqlldfersl
subfamily_Slingshot_pd Subfamily Slingshot 33-169 3.4e-28 92.1 In-house 20-159 (169) alignment 
Range on Protein: 33-169
Range on HMM: 20-159/169.0
QEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKI--KEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLG-GILVHCSAGVSRSASVVISYLM
 ..   .|.||   |.    |||.....|| .. .  .   ..|. | |.. ||...|. .|... . |||. .| |  .||||  |||||||.||.| |
skifdhvylGsewnasnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviayam

SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
  .   .  ...|... | .|.||.||..|| .||  .  
keyglsleealeyvkerrsvikPnkgflkqleeyeGilea
0041856 (Phosphotyrosine protein) phosphatases II 30-171 1.6e-27 91.6 In-house 17-176 (182) alignment 
Range on Protein: 30-171
Range on HMM: 17-176/182.0
FDAQEVIPNLYIGSISA--------------ATCTTSLKEHKITHILSISTNPPKIKEF-----TTLCINIEDESQKDissyFQQCHGFIENGRKLGG-I
 |  .. .|||.||  |              |   . |||..||.|....  .   ...     . |.....| .  |    ..... |||  .. || .
rdldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlteelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpv

LVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRP--CIQPNTGFINQLINYEATILKNQ
||||||||.|....|. ||| .   ..  .....|. ||  .|.|| .|. ||. .|   ||..
lVHCsaGvgRtgtlvaaylmkklgvsleeavklvrsrRpgmvitpnqyfflqlallellllkkt
subfamily_DSP8_pd Subfamily DSP8 32-170 3e-27 89.1 In-house 15-157 (159) alignment 
Range on Protein: 32-170
Range on HMM: 15-157/159.0
AQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPK---IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKL-GGILVHCSAGVSRSASVVISY
 .....|||.||   .   . |..  |...| .|.. ||   .||   | . ..|. . ... .|..   ||.  ..  | .|||. || ||||.|.|.|
ptrilknlylGsqkdvlseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiay

LMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKN
.|  .   .  . ..... || |.||  |..||..|| .. ..
imktlemsldeayrfvkekrptispnlnflgqLleyekelkll
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 36-165 6.6e-27 87.7 In-house 7-150 (154) alignment 
Range on Protein: 36-165
Range on HMM: 7-150/154.0
IPNLYIGSISAATCTTSLKEHKITHILSISTNPPK--IKE---------FTTLCINIEDESQKDISSYFQQCHGFIENGR---KLGGILVHCSAGVSRSA
  .|||.|  ||     |....|..|| ...  .    .|         .  | ... |. . ||   ....  ||..     . ...|||. .||||||
aiflyissfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsa

SVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEA
...|||||     ..  ... |.. |. |.||.||..||  .| 
allisylmdklkislslalellkdsryiikPnqGflkqleifek
0043147 (Phosphotyrosine protein) phosphatases II 32-169 7.4e-27 89.6 In-house 19-162 (172) alignment 
Range on Protein: 32-169
Range on HMM: 19-162/172.0
AQEVIPNLYIGSISAATCTTSLKEHKITHILSISTN-----PPKIKEFTTLCINIEDESQKdISSYFQQCHGFIEN---GRKLGGILVHCSAGVSRSASV
 ...|.... ..   |     |||..||||... .      . .   .. |.....| .   ........  ||..    .. | .||||||||.|.. .
pdrfiatqgplrntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtl

VISYLMSvFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
|. |||     ..  .....|. ||.. .| .....|  .| ..| 
vaaylml.lglsleeavalvrekRpgavqnpsqyrflyyfekllll
0049772 (Phosphotyrosine protein) phosphatases II 54-167 1.3e-26 89.5 In-house 167-273 (314) alignment 
Range on Protein: 54-167
Range on HMM: 167-273/314.0
KehkithilSISTNPPKIKE--FTTLCINIEDeSQKDISSYFQQCHGFIENGRKLGGILVHCSAGVSRSAS-VVISYLMSVFFKPFWYCMQYLRNIRPcI
|        .. ..|.. ..  .. |.|...|  . .....|...  |||. .| | .||||.||..|... ||. |||. .  ..  .....|..|| |
k........eelydpelferlgikylripvpD.gsaplledfdeflefieeadkggpvlvHCkaGkgRtgtfvvaaylmkllgvsleealedvrlkRp.i

QPNTGFINQLINYEATI
.|| |||.||..||   
npnpgfieqleqyefil
0049260 (Phosphotyrosine protein) phosphatases II 32-164 3.4e-26 87.2 In-house 8-146 (152) alignment 
Range on Protein: 32-164
Range on HMM: 8-146/152.0
AQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNPPKIKE-----FTTLCINIEDESQKDISSYFQQCHGFIEN--GRKLGGILVHCSAGVSRSASVV
 .|.|.....|. ..|     |||..||.|... .  .. |.     .. |.....| .  |.| ...... |||    .| | .||||||||.|.. .|
pfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlv

ISYLMSvFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYE
. |||  .  ..  .....|. ||.. || |.. .| ..|
aaylml.lgvsleeavalvrekRpgavpnpgqlrflyefe
subfamily_DSP3_pd Subfamily DSP3 25-170 5.7e-26 85.1 In-house 4-160 (162) alignment 
Range on Protein: 25-170
Range on HMM: 4-160/162.0
EEEICFDAQEVIPNLYIGSISAATCTTSLKEHKITHILSIST--------NPPKIK--EFTTLCINIEDESQKDISSYFQQCHGFIENG--RKLGGILVH
|.  . ...|| |.||.|  ..|.  . ||.  |||.|  .         ..   |  |.. | ....|  . |.| ||..   ||..   .| | .|||
erllskevdevypklyvgdeavakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvh

CSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRpCIQPNTGFINQLINYEATILKN
| .|||||| .|. ||| .        ..  |. | .|.||.||..||....  . ..
cvvGvsRsatlvlayLmirrkmtlveairtvrkkR.eilPneGFlkqLaeldeelkrk
subfamily_MKPLT_pd Subfamily MKPLT 38-168 1.4e-25 83.7 In-house 28-161 (164) alignment 
Range on Protein: 38-168
Range on HMM: 28-161/164.0
NLYIGSISAATCTTSLKEHKITHILSISTNPPK--IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISYLMSVFFK
.|| |  . ||  . ||. |||||. .|..  .   | .  | ...||||.. .||....   |. .  . || .||||  |.|||.|| . .|..    
tlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgw

PFWYCMQYLRNIRPCIQPNTGFINQLINYEATIL
 .    .||.. | ...|| ||. || ..|  ||
tlkeayeylkerrsivapnrGflkqlakfeelil
subfamily_MKPLV_pd Subfamily MKPLV 38-168 1.4e-25 83.7 In-house 28-161 (164) alignment 
Range on Protein: 38-168
Range on HMM: 28-161/164.0
NLYIGSISAATCTTSLKEHKITHILSISTNPPK--IKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISYLMSVFFK
.|| |  . ||  . ||. |||||. .|..  .   | .  | ...||||.. .||....   |. .  . || .||||  |.|||.|| . .|..    
tlylGnakhatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgw

PFWYCMQYLRNIRPCIQPNTGFINQLINYEATIL
 .    .||.. | ...|| ||. || ..|  ||
tlkeayeylkerrsivapnrGflkqlakfeelil
0046846 (Phosphotyrosine protein) phosphatases II 30-169 7.5e-25 83.1 In-house 10-174 (176) alignment 
Range on Protein: 30-169
Range on HMM: 10-174/176.0
FDAQEVIPNLYIGSIS----------AATCTTSLKEHKITHILSISTN--------PPKIKE-----FTTLCINIEDESQKDIsSYFQQCHGFIENGRKL
.|  ....||..||             |.    |||..||..... .         |   .|     .. |.....| .  |. ......  ||.. .| 
ldldyinanlilgsrpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealke

G-GILVHCSAGVSRSASVVISYLMSV-FFKPFWYCMQYLRNIRP-CIQPNTGFINQLINYEATILK
|  .|||||||..|.. .|. ||.   .. .   .....|..|| .. .. ... .|  .|  .||
ggpvlVHCsaGigRtgtlvaayllelekglsveealalvreqRplgavqtpeQyrflyefellllk
PTEN_1 30-170 4e-24 80.5 In-house 35-194 (196) alignment 
Range on Protein: 30-170
Range on HMM: 35-194/196.0
F------DaqEVIPNLYIGSISAATC-TTSLKEHKITHILSISTNPPK--------I---KEFTTLCINIEDESQKDISSYFQQCHGFIENGRK---LGG
.      .  |....||.||.. . .   .|||..||.... |  ..         .   . .. | . |||    ..|. |  |  |||  ..    . 
apsrpllq..eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnv

ILVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKN
.|||| ||..||. ||..|||.     .   ....|  ||.. ||... ..|..|.| .|..
VlVHCkaGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae
0045098 (Phosphotyrosine protein) phosphatases II 28-169 6.6e-24 80.2 In-house 18-273 (278) alignment 
Range on Protein: 28-169
Range on HMM: 18-273/278.0
ICFDAQEVIPNLYIGSIS-----------------------------------------AATCTTSLKEHKITHILSIST--------------------
.... .|. |.||.|...                                         .|     |.|..||.|... .                    
llgipseitpalylgnldknRykdilpydhsrVkdYINAsyidgypkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekcaqywpeggslt

-------------------------------NPPKIKEFTTLCI-NIEDESQKDIS--SYFQQCHGFIENGR---------------KLGGILVHCSAGV
                               .  .  ..| |.. ...| .  . .  ..|...  ||.. .               . | .||||||||
ygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsggpvlVHCsaGv

SRSASVVISYLMSVF---FKPFWYCMQYLRNIRPC-IQPNTGFINQLINYEATILK
.|.. .|. |||         .  . ..||. ||. ...| .....|. ... .|.
gRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllelll
0045450 (Phosphotyrosine protein) phosphatases II 52-169 2.1e-22 75.7 In-house 126-305 (307) alignment 
Range on Protein: 52-169
Range on HMM: 126-305/307.0
SLKEHKITHILSISTNPPK------------------------------IKEFTTLCINIEDE-----------------SQKDISSYFQQCHGFIENGR
 |.|...|.|.....  ..                               ...| ......|                     .....|...  |||  |
mlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevr

-------KLGGILVHCSAGVSRSASVVISYLMSVFF--------KPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
       | | .||||||||.|...... ||| . .         ..  ....||. ||.. .| ... .|.....  |.
kaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelll
0037934 (Phosphotyrosine protein) phosphatases II 28-167 5.3e-22 74.0 In-house 35-241 (243) alignment 
Range on Protein: 28-167
Range on HMM: 35-241/243.0
ICFDAQEVIPNLYIGSI--------SAATCTTSLKEHKITHILSIST-----------------------------------------------NPPKIK
|. .  .| |.|....          .|.    |.|..||.|... .                                               ....  
inanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseehlddytvrtlllenldlddltrl

EFTTLCINIED----ESQKDISSYFQQCHGFIEN-------GRKlGGILVHCSAGVSRSASVVISYLMSVF-FKPFWYCMQYLRNIRPC-IQPNTGFINQ
 .  ..... |    .| .|. ....... |||.        .. | .||||||||.|.. ... |||      ..  ....||. ||. . .. ... .
vihyhylpwpdhgvPdspedlldfldevrefieellsllaldsg.gpvlVHCsaGvgRtGtliaaylmllllgvdleeavkllreqRpgkavqtpsqyrf

LINYEATI
|. ... .
lyeallel
0040439 (Phosphotyrosine protein) phosphatases II 52-169 7.6e-22 73.6 In-house 73-247 (249) alignment 
Range on Protein: 52-169
Range on HMM: 73-247/249.0
SLKEHKITHILSISTNP---------------------------------------------PKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRK-
 |.|..||.|.....                                                . ...| |.|.. |    .....|...  |||  || 
mlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrka

------LGGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
       | .||||||||.|.. ... |||          ..  ....||. ||.. .| ... .|..... .|.
leelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll
subfamily_STYXL1_pd Subfamily STYXL1 33-169 3.1e-21 69.2 In-house 12-155 (157) alignment 
Range on Protein: 33-169
Range on HMM: 12-155/157.0
QEVIPN-LYIGSISAATCTTSLKEHKITHILSISTNPPKIK----E-FTTLCINIEDESQKDISSYFQQCHGFIENGRKLG-GILVHCSAGVSRSASVVI
 ||.|. ||.|  . |.  .  |. |.   . .|..  |.     .    | |..||| . |. . ...   |||. .| |  .||    |.||||.|.|
vevlPgklylGnykqaqnpaikkdlkvkahvnvsmdadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaavii

SYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILK
.|||      .  ...||.. .. ..|| .|..|| ..| ..|.
aylmyskkitlkkaykylkkCkenvkPnrafveqlseWekqllg
0036282 (Phosphotyrosine protein) phosphatases II 33-164 5e-21 70.6 In-house 13-166 (174) alignment 
Range on Protein: 33-164
Range on HMM: 13-166/174.0
QEVIPNLYIGSISAAtCTTSLKEHKITHILSISTNPP-----------------KIKEFTTLCINIEDESQKDISSyFQQCHGFIENGRKL---GGILVH
 .. |.|..|.  .|     |||..||....  .  .                 .   .. |.....| .  |.|  ....  |.|. ..    | .|||
syitprliagqgpla.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVH

CSAGVSRSASVVISYLMSVFFK-PFWYCMQYLRNIR---PCIQPNTGFINQLINYE
|||||.|.. .|. ||| .  . ..   ....| .|   |.. .. ... .|  .|
CsaGvgRtGtlvaaylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfe
0042113 (Phosphotyrosine protein) phosphatases II 34-168 1e-20 69.6 In-house 49-243 (245) alignment 
Range on Protein: 34-168
Range on HMM: 49-243/245.0
EVIPNLYIGSISAATCTT----SLKEHKITHILSIS------------------------------------------------TNPPKIKEFTTLCINI
.. |......  ..  .      |.|..||.|....                                                 .... . .. .....
ritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpw

EDESQKDISSYFQQCHGFIEN---GRKLGGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATIL
.| .  |......... |...     . | .||||||||.|.. ... |||     .    ..  ....||. ||.. .. ... .|. ...  |
pdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
0051082 (Phosphotyrosine protein) phosphatases II 30-163 2.8e-20 67.9 In-house 6-149 (151) alignment 
Range on Protein: 30-163
Range on HMM: 6-149/151.0
FDAQEVIPNLYIGSISAATCTTSLKEHKITHILSISTNP--------PKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRK--LGGILVHCSAGVSR
...  | ..||...   |     |||..|..|... . .         .  ... |.| |.| .  ... .|...  |.|  ..   | .|||||||..|
infsyvtgglyrsggpladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgR

SASVVISYLMSvFFKPFWYCMQYLRNIRP-CIQPNTGFINQLINY
.. .|. |||     ..  .....| .|| ..|||..|. ||. .
TGtlvalylml.lgvsleealeeyrlkrpgvvqpnqqflfqlfal
0040438 (Phosphotyrosine protein) phosphatases II 53-173 1.3e-19 66.0 In-house 106-281 (317) alignment 
Range on Protein: 53-173
Range on HMM: 106-281/317.0
LKEHKITHILSISTNPP-----------------------------KIKEFTTLCINIEDE----------------SQKDISSYFQQCHGFIENGRKL-
..|...|.|... .  .                             . ...| ... .||                    .. ......  |.|  |.  
vweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreal

----GGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQNV
    | .||||||||.|...... |||        .  .  ....||. ||.. .. ... .|. ... .||. ..
edpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrklt
0039614 (Phosphotyrosine protein) phosphatases II 52-170 2.4e-19 65.4 In-house 120-291 (297) alignment 
Range on Protein: 52-170
Range on HMM: 120-291/297.0
SLKEHKITHILSISTNPPK--------------------------------------------IKEFTTLCINIEDESQKDISSYFQQCHGFIENGR---
 ..|...|.|... .  ..                                             .    ..... | .  ........   .... .   
mvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealael

-KLGGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKN
 | | .||||||||.|...... |||     .     .  ....||. ||.. .. ... .|.....  ||.
pkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 38-165 1.2e-18 61.0 In-house 14-145 (148) alignment 
Range on Protein: 38-165
Range on HMM: 14-145/148.0
NLYIGSISAATCTTSLKEHKITHILSISTNPPKIKEFTT---LCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISYLMSVFF
 |..||   |.    ||.  .|.| . . . ... .  .   | ....|. ..|.|..|..   |... .. |. .|||.  |||||. ... .|.    
fLFlGskksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkr

KPFWYCMQYLRNIRPCIQPNTGFINQLINYEA
.     ... .. |. ..|| ||..|| ..| 
vslkealalvkskrryvdpnlgfLkqLaeleq
0036941 (Phosphotyrosine protein) phosphatases II 33-174 3.6e-18 61.3 In-house 20-283 (297) alignment 
Range on Protein: 33-174
Range on HMM: 20-283/297.0
QEVIPNLYIGSISAATCTTSLK----------------------------------------------------------EHKITHILSIST--------
.|. |.|..||.|.|     |.                                                          |...|.|.....        
eellpllllgslsvallpenleknRykdilpydhtRVklddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrek

----------NPPKIKEFTTLCINIED-------------------------------ESQKDISSYFQQCHGFIE-------NGRKLGGILVHCSAGVS
          .. . ..||  ....|                                    .. ......  |||       . .. | .||||||||.
caqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvg

RSASVVISYLM--------SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQNVI
||..... .||             ..  ....||. ||.. .. ..  .|. ...  ||.....
RsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltk
0043336 (Phosphotyrosine protein) phosphatases II 53-166 2.9e-17 58.5 In-house 108-275 (278) alignment 
Range on Protein: 53-166
Range on HMM: 108-275/278.0
LKEHKITHILSIS-----------------------------------------------TNPPKIKEFTTLCINIEDESQK-DISSYFQQCHGFIENGR
..|...|.|...                                                 .... .     .... | .   ..|.... .. ..|  .
vwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale

-KLGGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEAT
 . | .||||||||.|.. ... ||.     .  . ..  ....||. ||.. ..  .. .|..... 
dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 39-166 4e-17 55.7 In-house 6-140 (145) alignment 
Range on Protein: 39-166
Range on HMM: 6-140/145.0
LYIGSISAATCTTSLKEHKITHILS------ISTNPPKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLG-GILVHCSAGVSRSASVVISYLMSV
||.||.  |  .. |.|  |. |.       ....  | .....| |  ||    |.| .|..   ||. |.. | |..||| |||||| .| ...||  
lyvgsalhandvptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmky

FFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEAT
    .    . .|  |    ||  |...|.| |  
cnmtlseaarqvrsnrllaypnvtflknllnlekq
0038934 (Phosphotyrosine protein) phosphatases II 55-170 3.4e-16 54.9 In-house 54-179 (194) alignment 
Range on Protein: 55-170
Range on HMM: 54-179/194.0
EHKITHILSI--STNPPKIKEFTTLCINIEDE---------SQKDISSYFQQCHGFIENGRKlGGILVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYL
 .|.......  ..     .||. . | . .          |.. . .... .. |...  . | ..||| ||..|.. .|..||. ..  .   .....
nvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdeflnedpg.gvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialf

RNIRPCIQPNTGFINQLINYEATILKN
| .|| . || .....|  .  .. |.
rekRpgaipnqdyleallkrykelrka
0051429 (Phosphotyrosine protein) phosphatases II 50-171 9.5e-16 53.7 In-house 38-228 (272) alignment 
Range on Protein: 50-171
Range on HMM: 38-228/272.0
TTSLKEHKITHILSISTN--------PPKIKEFTTLCINIEDESQKDISSYF------------------------------------------------
   |||..|..|... .         .. .  .. |...|.|.|  .|. ..                                                
fwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpq

QQCHGFIENGRKLGGILVHCSAGVSRSASVVISYLMSvFFKP--------------FWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQ
.... ..|  .. | .|||||||..|.. ||  .|.     .                 ....|| .||.. .. ... .| .... .|.. 
eallellellldggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellrsl
subfamily_MSG5_pd Subfamily MSG5 85-171 3.7e-13 42.9 In-house 81-164 (165) alignment 
Range on Protein: 85-171
Range on HMM: 81-164/165.0
SQKDISSYFQQCHGFIENGRKlggILVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATILKNQ
  ||.|.  .  |    ...|   |||||  |.|||||....|.|  .   .  . . |..    |.|. |.| ||...|... |. 
ivkdlsrltriihaatskrkk...ilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewevalskks
0047943 (Phosphotyrosine protein) phosphatases II 51-162 2.8e-12 42.1 In-house 144-266 (273) alignment 
Range on Protein: 51-162
Range on HMM: 144-266/273.0
TSLKEHKITHILSIST--NPPKIKEFTTLCINIEDE----SQKDISSYFQQCHGFIENGRKLGGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYC
.  |.. ... | ..   .. . .    .. .. |     | ... ....... ..|. .. | ..|||||||.|...... .|.           .  .
eetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvlea

MQYLRNIRPCIQPNTGFINQLIN
...||. ||.. ..  .. .|..
vkllrsqRpgmvqtpeqyrflye
0046845 (Phosphotyrosine protein) phosphatases II 40-152 2.4e-11 39.0 In-house 131-258 (284) alignment 
Range on Protein: 40-152
Range on HMM: 131-258/284.0
YIGSISAATCTTSLKEHKITHILSIST---NPPKIKEFTTLCINIED----ESQKDISSYFQQCHGFIENGRKLGGILVHCSAGVSRSASVVISYLMSVF
..| ..  .  .  |.. ... |...    . . ..     .... |    .| .|. ....... ..||  . | |.|||||||.|.. ... .|.   
tygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleq

--------FKPFWYCMQYLRNIRPCIQP
          ..  ....||. ||.   
lekeglllgvdvleavkrlreqRpgmvq
0051299 (Phosphotyrosine protein) phosphatases II 42-153 3.7e-10 35.2 In-house 147-271 (288) alignment 
Range on Protein: 42-153
Range on HMM: 147-271/288.0
GSISAATCTTSLKEHKITHILSIS------TNPPKIKEFTTLCINIEDESQKD-ISSYFQQCHGFIENG-RKLGGILVHCSAGVSRSASVVISYLM----
| |.  .  .  ... ... | ..       .  ...     ..|. | .  | ...... .. ...    . | ..|||||||.|.. ... .|.    
gditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleql

-SVFFKPFWYCMQYLRNIRPCIQPN
       .   ...||. ||.. ..
ekeggvdvleavkrlreqRpgmvqt
0050432 (Phosphotyrosine protein) phosphatases II 56-152 8.8e-10 33.9 In-house 180-283 (308) alignment 
Range on Protein: 56-152
Range on HMM: 180-283/308.0
HKITHILSISTNPPKiKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKL---GGILVHCSAGVSRSASVVISYLM-----SVFFKPFWYCMQYLRNIR
. ..  | .. .  . ...|   .   .    .. ......  |.|  ||    | |.|||||||.|.. ... .|.           .  ....||  |
dytvrtleltnlgdg.esrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqR

PCIQP
|.  .
pgmvq
subfamily_PTPMT1_pd Subfamily PTPMT1 54-168 1.9e-09 32.2 In-house 55-169 (171) alignment 
Range on Protein: 54-168
Range on HMM: 55-169/171.0
KEHKITHILsISTNPPKIKEFTTLCINIEDESQKDISSYFQQCHGFIENGRKLGG-ILVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRPCIQP
.|......   ||.  |    . | ... |  ..      ..   |||. ...|  . ||| || .|||..|..|||          ...|...|. |. 
eeyelkala.nsteewkklgveqlqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirl

NTGFINQLINYEATIL
..   ..| .|| ..|
akkqwkalqeyeekll
PTPc_DSPc_SM00012 86-136 2.1e-08 29.7 In-house 19-69 (105) alignment 
Range on Protein: 86-136
Range on HMM: 19-69/105.0
QKDISSYFQQCHGFIENGRKLGGILVHCSAGVSRSASVVISYLMSVFFKPF
...| ....... . ..  . . ..|||||||.|.. .|  ...   ..  
sdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleke
0048567 (Phosphotyrosine protein) phosphatases II 87-168 2.4e-07 25.3 In-house 54-139 (157) alignment 
Range on Protein: 87-168
Range on HMM: 54-139/157.0
KDISSYFQQCHGFIENGR-KLGGILVHCSAGV---SRSASVVISYLMSVFFKPFWYCMQYLRNIRPCIQPNTGFINQLINYEATIL
  . ..... . |..  . . . | |||.||    .|.| .. .||. .. .. . ....|| .|| ..|     . | .|. |.|
ailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsvpfrdasyllslynltll
subfamily_CDC14_pd Subfamily CDC14 51-149 3.1e-07 24.5 In-house 206-306 (328) alignment 
Range on Protein: 51-149
Range on HMM: 206-306/328.0
TSLKEHKITHILSISTNPPKIKEFTTLCINIEDESQKDISSYFQQC-HGFIENGRK-LGGILVHCSAGVSRSASVVISYLMSVFFKPFWYCMQYLRNIRP
.  .....|... .  .  . |.||   .. .|    | |   ..  . |.|   |  |.| ||| ||. |  ... .|||  .      .. .|| .||
eyfrknnvttvvrLnkklYdakkftdaGfdhkDlffiDGstPsdaivkkfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrP

C
 
G
subfamily_Laforin_pd Subfamily Laforin 96-136 2.6e-06 20.4 In-house 103-140 (183) alignment 
Range on Protein: 96-136
Range on HMM: 103-140/183.0
CHGFIENGRKlggILVHCSAGVSRSASVVISYLMSVFFKPF
 |...|.| .   . ||| ||| ||...|  .|. |.   .
lhallekghi...vyvhcnagvgrstaivcgflqyvlgwsl
DSPc_SM00195 88-129 8.4e-06 20.7 In-house 194-218 (263) alignment 
Range on Protein: 88-129
Range on HMM: 194-218/263.0
DissyfqqchgfiengrkLGGILVHCSAGVSRSASVVISYLM
                   | |.|||||||.|....|   ..
s.................sgpivVhCsaGvgRtgtfvtidii
PTPc_SM00194 88-129 8.4e-06 20.7 In-house 194-218 (263) alignment 
Range on Protein: 88-129
Range on HMM: 194-218/263.0
DissyfqqchgfiengrkLGGILVHCSAGVSRSASVVISYLM
                   | |.|||||||.|....|   ..
s.................sgpivVhCsaGvgRtgtfvtidii