Synonym: 4E, CG6899, CT21187, DPTP4E, Dmel\CG6899, PTP4E, PtP4E, R-PTP 4E, Dmel_CG6899, Ptp4E
Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRB_pd | Subfamily PTPRB | 1306-1589 | 1.4e-138 | 455.9 | In-house | 4-289 (293) | alignment | ||
Range on Protein: 1306-1589
Range on HMM: 4-289/293.0
NRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPL
..|.....|.||.. |.||||.|||||.||||.||.|||...|.|..|| |||.||||||||||.||....|..|||||||||.||.|||||||.|||||
skpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPl
HSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVR
..|...||||.||..|..|||||...|||..||..||| |. ...||||||.|. .....|| | |...... |.| .|..|||.|||.|||| ...|..
petvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktlld
FVRAFRDVI--GTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKE
|||..|..| ...|||.|||||||||.||||||||.||.|...||||||||| ..|.||...||||.||..||||.|..|. ||
fvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkke
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1307-1589 | 1.4e-112 | 372.2 | In-house | 3-286 (564) | alignment | ||
Range on Protein: 1307-1589
Range on HMM: 3-286/564.0
RPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVgRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLH
.|..|... ||.. . |.||..|.||...... . .. || |.|..|||. ||..||||| .|..|. |.|||||||... |.......| |||||.
kpipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPla
STREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRvAMFYGDIKVQLIIDTHYHDWSISEFMV--SRNCESRIMRHFHFTTWPDFGVPEPPQSLV
.| |.||||.|| ||. |||||.. |||..||..||| .. ||...|.| ... | .| .| . ... ||| |.|||| ||| |||| ..||.
etiedFWRmvweqnsstiVmltkleEkgkvkchkYWPekg.tetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslL
RFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE-GKE
...| |.. .| ||.|||||||||.||||..| .|. |.... |||...| |.||.| .|||||.||. ||. .| |. |..
dlirkvralnepdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnt
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1306-1584 | 2e-100 | 331.2 | In-house | 2-285 (288) | alignment | ||
Range on Protein: 1306-1584
Range on HMM: 2-285/288.0
NRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPL
.....|... .... . |.. .. |||||| .. | .|.|.||.|..|||...|||||||| ||...|...|||||||.|..|.|..|.||.|||||
dteisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPl
HSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVdRVAMFYGDIKVQLIIDTHYHDWSISEFMVS------RNCESRIMRHFHFTTWPDFGVPEP
..| |.||||.|| |.| |||||...|.|||||.|||| . . ||||.| |. ....|. . ...|. . |||. .|||.|.|||.|||.
pntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpds
PQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAV
|..|..|.|..|... . |..|||||||||.||||||| .|....| ||....| .|. | .||||..||. ....||
pellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealley
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 1296-1587 | 1.9e-98 | 324.9 | In-house | 13-301 (308) | alignment | ||
Range on Protein: 1296-1587
Range on HMM: 13-301/308.0
AALPEGYITPNRPVHVKDFSEHYriMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLqpvddDDGSDYINANYMPGH--N
. .... . . ...|.|. ... ..|.. ...|||||| .| . .|.|.||.|..|||...|||||||| || |.|||||||.|..|. .
lfrdtsilvsslklsvldllkll..ekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssk
SPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVD--RVAMFYGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFT
.||.||.|||||..| | ||||.|| |.| |||||...|.|||||.|||| . . . ||...| |. ....|. . ..... . |||...|||.|
lprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhyt
TWPDFGVPEPPQSLVRFVRAFRDVIGTdmRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEG
.|||.|||. |..|..|... |.... ||.|||||||||.||||||| .|....| ||.|..| .|. | .||||..||. ....|| |.
nWpdhgvPpspeilldflelvrkslpg..gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1309-1590 | 5.8e-96 | 316.3 | In-house | 2-285 (318) | alignment | ||
Range on Protein: 1309-1590
Range on HMM: 2-285/318.0
VHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHST
..|.|. .| | . .. . .|||.|.|... . . .. |.|. |||..|||.|||.| |||..... |||||||||..|... ...| .|.|| |
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
REEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPvDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRN--CESRIMRHFHFTTWPDFGVPEPPQSLVRF
|.|||| || ||. |||||.. |.|..|...||| .. .. ||...|.| .... |. . || |.|. |||..| .|.|.||| |||| . ||. .
ieDfWrmvWeqnsavivmltqeeergkakvhryWP.skgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldl
VRAFRDVI-GTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEH
|| . . ....||.||||||||| |.|||.| .|..|.. ||.|..| .|..| |||||.||. |.. || |. .
vrqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdt
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 1311-1585 | 2.7e-95 | 314.6 | In-house | 2-276 (317) | alignment | ||
Range on Protein: 1311-1585
Range on HMM: 2-276/317.0
VKDFSEHYRIMSADSDFRFSEEFEELKHVGRDqACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTRE
|.|. ... . . . ...||||.| .. | .|.|.||.|..|||...|||||||| ||.|.. | .||||||.|..|.| .|.||.||||| .| |
vldlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntve
EFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVdRVAMFYGDIKVQLIIDTHYHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVR
||||.|| ... |||||...|.|||||.|||| . . |||..|.|. ...... . ...|. .. |||...|||.|.|||.|||. |..|..|..
dFwrmvweqgvtvivmLteleelgrekcaqYwpl.getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfle
AFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
| |... . |..|||||||||.|||||....|....| ||.. .| .|. | .|||..||. ....|| |
avrealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleyl
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 1329-1586 | 5.2e-94 | 310.0 | In-house | 2-275 (284) | alignment | ||
Range on Protein: 1329-1586
Range on HMM: 2-275/284.0
FSEEFEELKHVGRDQ--ACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDD-DGSDYINANYMPGH-----NSPREFIVTQGPLHSTREEFWRMCWESN
. |||||| .. .. .|.|.||.|. |||...|||||||| ||...|.| ..||||||.|..|. .....||.||||| .| |.||||.|| |
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
SRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSR---NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG--
.| |||||...|.|||||.|||| . . |||..| |. ....|. . ...... . |||...|||.|.|||.|||. |..|..|.|. |...
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSD---YVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
. ||.|||||||||.||||||| .|....| . ||....| .|. | .||||..||. ....|| |
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 1319-1588 | 2.5e-92 | 304.6 | In-house | 5-280 (297) | alignment | ||
Range on Protein: 1319-1588
Range on HMM: 5-280/297.0
RIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLqpvdDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWE
....... ....||||| .. . .| |.||.|..|||...||||||.| || ||.|||||||.|..|.. .|.||.|||||..| |.||||.||
llekllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvwe
SNSRAIVMLTRCFEKGREKCDQYWPVD-RVAMFYGDIKVQLIIDTH--YHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDV
|.. |||||...|.|||||.|||| . . . |||..|.|. .. . |. . .. |. | |||...|||.|.|||.|||| |.||..|....|.|
qnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkv
IGT--DMRPIIVHCSAGVGRSGTFIALDRILQHIH---KSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGK
. . |..|||||||||||||||.| .|| .. | |||. .| .|. | ..|||..||. ....|| | |
lkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1308-1582 | 1.1e-91 | 302.4 | In-house | 1-274 (278) | alignment | ||
Range on Protein: 1308-1582
Range on HMM: 1-274/278.0
PVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRdQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHS
|..|||. .... . ... ....||||| .. .|.|.||.|..|||...|||||||| ||.... | .||||||.|..|.| ||.||.|||||..
pisvkdllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpe
TREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPvdRVAMFYGDIKVQLIIDTHYHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVPEPPQSLVR
| | ||||.|| ... |||||...|.||.||.|||| . . |||..| |. .|..|. . . |. .. |||. .|.|.. |||.||||....|..
tvedFwrmvwelgvttivmLtelvelgrvkcaqYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllld
FVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
|..|.|... .. |..|||||||||.||||||...|....| ||.. .| .|. | .|||..||. ....||
flkavrealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeall
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 1308-1586 | 1.5e-91 | 301.5 | In-house | 3-280 (288) | alignment | ||
Range on Protein: 1308-1586
Range on HMM: 3-280/288.0
PVHVKDFsEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHS
|.|... .. ..||.. ||||.. | ...... . ..|. | .|||. ||||||. | ||. ... .|.|||||.|. |... ...| ||||| .
pihispv.akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPlad
TREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFV
| ..||.. .| .. ||||| |.|..||..||| . ||...|.|. . . .|. .... .. . . . ......||| |||| . |. ..
tvndfWelvyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllell
RAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
| |. ||||||||||||.||||||| ........||.|..|.| .||.| ..|||..||. |...|| . |
rqvkvanqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllslie
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 1304-1585 | 3.7e-91 | 300.9 | In-house | 9-289 (297) | alignment | ||
Range on Protein: 1304-1585
Range on HMM: 9-289/297.0
TPNRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDqaCSFANLPCNRPKNRFTNILPYDHSRFKLQPVDD-DDGSDYINANYMPGHNS-PREFIVT
... |.... . ..... |.| .. .|||||. . | .|.|.||.|..|||...|||||||| ||.|.|. | .||||||.|..|.. .|.||.|
lesipiplsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIat
QGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGReKCDQYWPVDRVamFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQ
||||..| | ||||.|| ....|||||...|.|| ||.|||| . |||..| |. .|.... . .. |..| |||...||..| |||.|||. ..
qgPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg..tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppsle
SLVRFVRAFRDVIGT--DMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
.| .|... |... . . .|..|||||||||.|||||....|....| ||.. .| .|. | .|||..||. ....|| |
llleflelvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallell
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 1319-1583 | 6.5e-91 | 299.8 | In-house | 4-270 (273) | alignment | ||
Range on Protein: 1319-1583
Range on HMM: 4-270/273.0
RIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLqpvdDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWE
....... .. ||||.|. . . .|.|.||.|. |||...|||||||| || .|.|||||||.|..|.|..|.||.||||| .| |.||||.||
llekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvwe
SNSRAIVMLTRCFEKGREKCDQYWPVDRV--AMFYGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVI
|.| |||||...|.|||||.|||| . . ||...| |. ....|. . ...... . |||...|||.|.|||.|||. ..||..|... |...
qnvrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkal
GT--DMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
. . |..|||||||||.||||||| .|....| ||.. .| .|. | ||||..||. ....||
ealpsngpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealle
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 1306-1585 | 1.2e-89 | 296.3 | In-house | 6-304 (307) | alignment | ||
Range on Protein: 1306-1585
Range on HMM: 6-304/307.0
NRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGR--DQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDD-DGSDYINANYM--------PGHNS
.... .... ..... .|. .. .|||.|..| .|.|.||.|..|||...||||||.| ||...|.. ..||||||.|. .|...
slfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydl
PREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVS---RNCESRIMRHFHFTTW
.|.||.|||||..| |.||||.|| ....|||||...|.|||||.|||| .. . ||...| |. .|.... . . |. . |||. .|||.|.|
krkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgw
PDFGVPEPPQSLVRFVRAFRDVIGT--DMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDY---VDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
||.|||. ...|..|... |..... . |..|||||||||.|||||.. .|....| ||.. .| .|. | .||...||. ....|| |
pdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
DSPc_SM00195 | 1329-1585 | 7.6e-88 | 289.6 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 1329-1585
Range on HMM: 2-262/263.0
FSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLT
..||||.|. .. .. |. . |. |||..|||||||.| ||.. ....|||||||||. |.|.....|.||||| || |.||||.|| ... |||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
RCFEKGREKCDQYWPVD-RVAMFYGDIKVQLIIDTHYH-DWSISEFMVSRNC--ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVH
...|.|.||||.||| . . .|.|.|.|. ... .. . .. .. . |.| ........||| |||. ..|.....||.. | ||.||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
|||||||.|||...| ||..... . |||| || ..||.| ||||..|| |....|...
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 1329-1585 | 7.6e-88 | 289.6 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 1329-1585
Range on HMM: 2-262/263.0
FSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLT
..||||.|. .. .. |. . |. |||..|||||||.| ||.. ....|||||||||. |.|.....|.||||| || |.||||.|| ... |||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
RCFEKGREKCDQYWPVD-RVAMFYGDIKVQLIIDTHYH-DWSISEFMVSRNC--ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVH
...|.|.||||.||| . . .|.|.|.|. ... .. . .. .. . |.| ........||| |||. ..|.....||.. | ||.||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkkskstssgpivVh
CSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
|||||||.|||...| ||..... . |||| || ..||.| ||||..|| |....|...
CsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1309-1600 | 2e-87 | 288.7 | In-house | 1-301 (563) | alignment | ||
Range on Protein: 1309-1600
Range on HMM: 1-301/563.0
VHVKDFSEHYRIMSADSDFRFSEEFE--ELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGS-DYINANYMPGHNSPREFIVTQGPL
|.||.|..| . ||.| .|||||| . ... .| ..... |.|. ||| .||..||.|| ||.|. . ... |||||||. |.. ..||.|||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgpl
HSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVaMFYGDIKVQLIIDTHYHDWSISEFMVSR-------NC-ESRIMRHFHFTTWPDFGVP
..| . |||| || |. |||.| |.||.|||.||| | . . || ..|.|| . .. .... .| . . .|..|.|.||| |||
kdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdes.etygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvP
EPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSlE
| . . ||. ... ||.|||||||||.||.|.|| .|. |.. . |..||.. .| .| |.|||| ||. .|. || .. .|| | .. .
ehslpvLifvkkssaankaeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellae.q
LHA
...
vee
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1307-1606 | 3.7e-85 | 280.7 | In-house | 12-317 (330) | alignment | ||
Range on Protein: 1307-1606
Range on HMM: 12-317/330.0
RPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLH
|. |... | || ||| .| |||. | . .. |. |. |||. ||||||.|| |.... . |||||| .. |.. .|| .|||..
fplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPke
STREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRvAMFYGDIKVQLIIDTHYHDWSISEFMVS---RNC---ESRIMRHFHFTTWPDFGVPEPP
| |.|||| || .| .||||| |. .||| |||| . .. ||.|.|.. .| |... .|.| .. .||..| ||||.|||.||| |
etvedfwrmiweqksativmltelkerkeekcaqywPdeG.lvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfep
QSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAV-LEGKEHLLADSLELH
. ....... . . ||.|||||||||.||||.|| .|. .. ||.|..| .|. | ||||..||. |.. || | | | . ||| |
iGmlkllkkvkklnqqsagpivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekh
ANDGYEV
. |.
lqklynk
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1306-1589 | 3e-82 | 271.2 | In-house | 2-287 (319) | alignment | ||
Range on Protein: 1306-1589
Range on HMM: 2-287/319.0
NRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDqACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPL
.....|... |..... . .. . .||..||. . | . |. . |..|||..|||.||..| .|...|. .|||||||... |.. ..|| ||.||
dteievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPl
HSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVaMFYGDIKVQLIIDTHYHDWSISEFMV---SRNCESRIMRHFHFTTWPDFGVPEPPQS
. | |.|||| || .| .||||. ||.. |. .||| . . || . |.| . . .|. |..... | . |.| . ||..| ||| .||| .|
entiedfWrmvWeeessivvmltklveklkvklkkywpeenf.eeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekats
LVRFVRAFRDVIG-TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKE
|. ... | |. .||.||||||||| ||||.|| .|..... .|.| .| .| | .|||...|| |.. ||...| .
lldllkrirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 1317-1586 | 1.1e-81 | 269.0 | In-house | 5-277 (281) | alignment | ||
Range on Protein: 1317-1586
Range on HMM: 5-277/281.0
HYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMC
| . .|.... | ||.|.|...|.|.. . .. . |. |||..|| ||..| |..| ... .||||||..|| ....|.|.||||. .. ..||.|
hlkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmv
WESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMV-SRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG
|| . .||||.|| |.|. || .||| |. .. |||..|. . .. . . .|.. ...|.| ......|.||| |||. .. |. | .. . .
weqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlklte
TDM-RPIIVHCSAGVGRSGTFIALDRILQHIH-KSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
.. |...||||||||.||.|||||...... . .|. .| .|||| .|||| || ... .| .|.
kktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 1345-1583 | 3.5e-81 | 267.7 | In-house | 3-244 (249) | alignment | ||
Range on Protein: 1345-1583
Range on HMM: 3-244/249.0
CSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPV
.|.|.||.|..|||...||||||||.||..... .||||||.|..| ...|.||.|||||..| | ||||.|| ....|||||...|.|||||.||||
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
dRVAMFYGDIKVQLIIDTHYHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGT--DMRPIIVHCSAGVGRSGTFIALDR
. . |||..|.|. ....|. . ..... . ||| .|...| |||.|||. ...|..|..| |... . . |..|||||||||.|||||..
.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaayl
ILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
.|....| ||.. .| .|. | .||...||. ....||
mleqlekelgvdleeavkllrsqRpgavqnpeqyrflyealle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1353-1582 | 8.1e-81 | 266.2 | Pfam-A | 1-234 (235) | alignment | ||
Range on Protein: 1353-1582
Range on HMM: 1-234/235.0
NRPKNRFTNILPYDHSRFKLqpVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-VDRVAMFY
|. |||...|||||..| || .... ||||||||. |......||.||||| || |.||||.|. ....|||||.. |||||||.|||| .. . |
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GDIKVQLI--IDTHYHDWSISEFMVSRNCES---RIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIH
|||||.| . .. ... .... .. ..|. |.....|.|.||| |||| |.||....|... .. |..|||||||||.|||.||| .|....
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqle
KSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
. . ||.. || .||.| |||...||. .....|
aeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 1353-1582 | 8.1e-81 | 266.2 | In-house | 1-234 (235) | alignment | ||
Range on Protein: 1353-1582
Range on HMM: 1-234/235.0
NRPKNRFTNILPYDHSRFKLqpVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWP-VDRVAMFY
|. |||...|||||..| || .... ||||||||. |......||.||||| || |.||||.|. ....|||||.. |||||||.|||| .. . |
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GDIKVQLI--IDTHYHDWSISEFMVSRNCES---RIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIH
|||||.| . .. ... .... .. ..|. |.....|.|.||| |||| |.||....|... .. |..|||||||||.|||.||| .|....
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqle
KSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
. . ||.. || .||.| |||...||. .....|
aeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 1314-1586 | 3.2e-80 | 264.6 | In-house | 14-291 (298) | alignment | ||
Range on Protein: 1314-1586
Range on HMM: 14-291/298.0
FSEHYRIMSADSDFRFSEEFEELKHVGR---DQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTRE
... .. . . ....||..|..| .. . |. | |. |||...|...|.|| |. .|.|. |||||| .. ... ||.||.||..| |
lqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetve
EFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPvDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNC--ESRIMRHFHFTTWPDFGVPEPPQSLVRFVR
.|||| .| .. .||||| |... |. .||| |. . ||.|.|.| . .. | . ...||.. ..| .|..|||.||| |||| .|.. ..|
dFWrmvteedigtiVmltnleeldktkyhkywP.degketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllr
AFRDvIGTDMR--PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
| .. |.||.|||||||||||||.| .|....|. ||.| .| ..||.|. .||||.||| |.. | .|.
kvra.sqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavleald
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 1323-1586 | 4.6e-80 | 264.2 | In-house | 3-273 (278) | alignment | ||
Range on Protein: 1323-1586
Range on HMM: 3-273/278.0
ADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKlqpvddddgsDYINANYMPGHnsPREFIVTQGPLHSTREEFWRMCWESNSR
|... ... |||.| . | . ...|....|..|||...|||||||| | |||||.|..|. |..||.||||| || . ||||.|| ...
alasldlllefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgit
AIVMLTRCFEKGREKCDQYWPvDRVAMFYGDIKVQLIIDTHYHDWSISEFMVS------RNCESRIMRHFHFTTWPDFGVPEPP--QSLVRFVRAFRDVI
.|||||...|.|||||.|||| .. . |||..| |. ....|. . ..| ..||| ..|.|...|||.|||. | .|. .... |...
vivmltelvelgrekcaqywp.eggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefireal
GT-------------DMRPIIVHCSAGVGRSGTFIALDRILQHIhkSDYVDIFGIVFAMRKERVF-MVQTEQQYVCIHQCLLAVLE
. . |..|||||||||.||..|.. .|... . ||.. .| .|. | . .||...||. ....|| .|.
kllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelll
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 1345-1584 | 9.5e-80 | 262.8 | In-house | 1-242 (245) | alignment | ||
Range on Protein: 1345-1584
Range on HMM: 1-242/245.0
CSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPV
.|.|.||.|..|||...||||||.|.||.|.. | .||||||.|..|.. .. ||.|||||..| | ||||.|| ....|||||...|.||.||.||||
ysvallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl
dRVAMFYGDIKVQLIIDTHYHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG-TDMRPIIVHCSAGVGRSGTFIALDRI
. . |||..|.|. .|. |. . ...|. .. ||| .|.|.. |||.|||. ...|..|... |... .. |..|||||||||.|||||....
.gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylm
LQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAV
|....| |... .| .|. | .|||..||. ....||
leqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1308-1585 | 1.3e-77 | 255.9 | In-house | 3-286 (307) | alignment | ||
Range on Protein: 1308-1585
Range on HMM: 3-286/307.0
PVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHS
.....| .| .. |.|| . .|.|.|.. |. ..... | |||. .| ..|. | ||... .. ||||||... |.. ..||. |.|. .
aiaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPvea
TREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDrVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNC-------ESRIMRHFHFTTWPDFGVPEPP
| ..|||| .| .. ||||. || |.||..|||.. . |||| |.|. . .|. | |. ||.. .|| . .|.|.|.|. ||| .
tigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPeva
QSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
..|..... |.. .. ||.|||||||||||.|.||| .||.... | |||| .| .|..| ..|| .||| ... ||
rgllklieqvrelyklnrsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldys
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 1348-1587 | 3.3e-77 | 254.1 | In-house | 4-244 (250) | alignment | ||
Range on Protein: 1348-1587
Range on HMM: 4-244/250.0
ANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREkCDQYWPVDRv
|. | |. |||...|...|.|| |.... |. |||||| .. |.. . ||.|||||..| |.|||| .| .| .||||| |.... . |||||..
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvek.
AMFYGDIKVQLIIDTHYHDWSISEFMVSRNCES--RIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGT-DMRPIIVHCSAGVGRSGTFIALDRILQH
| |||..|.| . .. |. . ....|.. .. ||.|..||..||| |||| .. . ... . . .|.||.|||||||||.|||.| .|..
aekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavler
IHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEG
..|. ||.| .. ..||.|. .|....||| ... .| |.
lkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 1309-1588 | 4.3e-77 | 254.0 | In-house | 4-281 (314) | alignment | ||
Range on Protein: 1309-1588
Range on HMM: 4-281/314.0
VHVKDFSEHYRIMSADSDFRFSEEFEELKHvGrdqaCSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHST
..|.| .. .. . . | ||.| | | |. || |||...||.||.|| .|...|.| ||||||... ... |..||||||||..|
irvadllqsiallkraegygfkeeyeslfe.g....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqet
REEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAmfYGDIKVQLIIDTHYHDWSISEFMVSR----NCESRIMRHFHFTTWPDFGVPEPPQSLV
..|||. .. |. .||||| |.|| || .||| | ||||||.|. . . . | |.. | |..|.|.|..|||..|| ..|.
vkdfWrlvydencasivmltelvevgrvkClkyWPedtev..ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgll
RFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA-VLEGK
..|| . .|.|||||| ||.|||||.| .|. |.. . ||.| .| ..|...| ||.||.||. |.. .| .| |.
klvrrvkksqeeeaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcge
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 1328-1586 | 8.2e-76 | 249.6 | In-house | 9-278 (290) | alignment | ||
Range on Protein: 1328-1586
Range on HMM: 9-278/290.0
RFSEEFEELKHVGR----DQ--ACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNS
.|..||..||.. . .. . .. . |. |||. .|||||.|| .|. ....||||||||.. | ... |.| .|||| | ..|||| || |
efakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknv
RAIVMLTRCFEKGREKCDQYWPVD-RVAMFYGDIKVQLIIDTHYH-DWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMR
. .||. | .| |. ||..||| .. .|...|.|. . . . |. | . | .. |||... ||.| ||| |||. ..||.......|.. ..
eivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqeseda
PIIVHCSAGVGRSGTFIALDRILQHIHKSD---YVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
|..||||||||| || ||.| . . ... .|.| .| .||.|. .|||..||. ...... ...
PlvvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvq
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 1330-1583 | 1.7e-75 | 248.9 | In-house | 19-288 (297) | alignment | ||
Range on Protein: 1330-1583
Range on HMM: 19-288/297.0
SEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTR
|.|..|... ..|..| |||.|..| ||..| .|. ||.|. |||||||.. |.. .. || |||||. | ..|||| ||.. . ||| ||
skeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttr
CFEKGREKCDQYWP-VDRVAMFYGDIKVQLIIDTHYHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTD---------
. |.|| || |||| . .. .||..|. . . ...|. .. . .. .. ||| . || |..|||.|||. .||. .... |. ..
vvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewk
----MRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
||.||||||.||.||||.|| |..... . ||.. | .|. | |..||..||. ....|
ghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 1308-1587 | 4.6e-74 | 244.3 | In-house | 3-285 (305) | alignment | ||
Range on Protein: 1308-1587
Range on HMM: 3-285/305.0
PVHVKDFSEHYRIMSADSDFRFSEEFEELKHVgrDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHS
.. ..|.... . ....|| . .....| . .... . |. |||...| ..|..|..|.. ...| ||||||.|. |... ..||.||||..
iialddlaayikearvysdkgleaqykslyee..eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkn
TREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVA-MFYGDIKVQLIIDTHYHDWSISEFMVSR---NCESRIMRHFHFTTWPDFGVPEPPQSL
| ..|||. .| . |||||. | |..|| |||| . .|...|.| ... |. . .. .| . ||| . ....|.||| |||. . ||
tvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsl
VRFVRAFRDVIGTDMR-PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEG
..... . | |..|||||||||.|.|||.| |....| . ||.|... ..|..|. |||| .||| .|. | ..
lslikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitc
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 1345-1582 | 1e-73 | 243.2 | In-house | 2-239 (243) | alignment | ||
Range on Protein: 1345-1582
Range on HMM: 2-239/243.0
CSFANLPCNRPKNRFTNILPYDHSRFKLqpvdddDGSDYINANYMPGHnsPReFIVTQGPLHSTREE----FWRMCWESNSRAIVMLTRCFEKGREKCDQ
.|.|.||.|..|||...|||||||| || .||||||||.... || .|.||||| .| |. ||||.|| ....|||||...|.|||||.|
fsiallpenlsknrysdilpydhsrvkl......egsdyinanliyvt..pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaq
YWPvDRVamFYGDIKVQLIIDTHYHDWSISEFMVSR---NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGT--------DMRPIIVHCSAGV
||| . | |||..|.|. .|..|. . ...... . ..| .|.|.. |||.|||. |..|..|... |..| . .|..|||||||
ywp.gev..tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGv
GRSGTFIALDRILQHIhksDyVDIFGIVFAMRKERVF-MVQTEQQYVCIHQCLL
||.||.||.. .|... . ||.. .| .|. | . .|||..||. ....||
gRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeall
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 1327-1589 | 1.8e-73 | 242.2 | In-house | 26-301 (306) | alignment | ||
Range on Protein: 1327-1589
Range on HMM: 26-301/306.0
FRFSEEFEELKHVGRDQACS--FANLPCNRPKNRFTNILPYDHSRFKLQpVDDDDGSDYINANYMP--GHNSPREFIVTQGPLHSTREEFWRMCWESNSR
|.||||||.. . | .. | |. |||. ||||.||.| .|. .. |||||||||. ..| ...| ||| |..| ..|||| |. |||
agfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensr
AIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVS---RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG----
|||.|. |.|.||| .||| ||.|.|. . ... .|. . |..|| .. |.| ....||..||| |||. |. .. |.. .
vivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeelee
TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDY---VDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKE
....||.||||||.|| |||| .| .|. |.|. . .|| .| .|. | .||||||| ... . . .| |.
aeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyietkk
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 1307-1583 | 1.7e-72 | 239.4 | In-house | 9-289 (319) | alignment | ||
Range on Protein: 1307-1583
Range on HMM: 9-289/319.0
RPVHVKDFSEHYRIMSADSDF-----RFSEEFEELKHVGRDQA-CSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIV
| |.|| .|. .| ||| .. || . ..| . | .||||. |. |||..|||..|... ||.... ..|||||| .. |. .. .|
sdvavpdfpayyqqlsnksdfdddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyia
TQGPLHSTREEFWRMCWESNSRAIVMLTrcfekgREKCDQYWPVDRVAMfYGDIKVQLIIDTHYHDWSISEFMVSR---NCESRIMRHFHFTTWPDFGVP
.|||| | ..|||| ||.|. .||.|| ..|| |||| . | .. ||.. . ... . .. .|. . . | .. ||| ||| |||
aqGPldntladfWrmiweyncstivllt......kdkcsqywplkivik.eerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvp
EPPQSLVRFVRAFRDVIG--TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
. | |.|.|. | . . ..|.|||||||||.|..|.|| .|. ... . ||.. .| .|..| .|| || |. ||
dypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 1340-1583 | 4.3e-70 | 231.4 | In-house | 11-253 (284) | alignment | ||
Range on Protein: 1340-1583
Range on HMM: 11-253/284.0
GRDQ-ACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTrcfekgREKC
| . .||||. |. |||...||..|... ||.... ..|||||| .. |. .. .| ||||| | ..|||| ||.|. .||.|| ..||
gvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkc
DQYWPVDRVAMfYGDIKVQLIIDTHYHDWSISEFMVSR---NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG--TDMRPIIVHCSAGVGRSG
|||| . | .. ||.. . ... . .. .|. . . | .| ||| ||| |||. | |.|.|. | . . ..|.|||||||||.|
sqywplkivik.eerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtg
TFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
..|.|| .|. ... . ||.. .| .|..| .|| || |. ||
vyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 1327-1595 | 6.5e-70 | 230.1 | In-house | 6-278 (290) | alignment | ||
Range on Protein: 1327-1595
Range on HMM: 6-278/290.0
FRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDddgsDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVM
...| ...... .| .. |.|| ||..||. .. |||||| ||. | |||||. . .. |..|.||||| .| . ||.| || .|.|.||
rlykeiyldirkeasdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvm
LTRCFEKGREKCDQYWPVDRV--AMFYG--DIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRD--VIGTDM
| .. ||.. || |||| . .. . .||.|| ... . .. . . |.| . |||.|||||||||| |.....|. |. .. .|.
lnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdv
RPIIVHCSAGVGRSGTFIALDRILQHIHKSDY---VDIFGIVFAMRKERVFMVQTEQQyvcIHQCLLAVLEGKEHLLADS
| ..|||||.||||||. .| .| .|.|.| ||| . ..|| |. ..|| .| .. ||.||| . ||
GpavihcsaGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadq...lrfsylaileGakvikgds
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1328-1591 | 2e-68 | 225.5 | In-house | 20-283 (315) | alignment | ||
Range on Protein: 1328-1591
Range on HMM: 20-283/315.0
RFSEEFEELKHVGRDQACSfANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
||||| .| . . | . | .|||. ||||.|..| ||. .||. |||||| |... .. . .| .||||... ..|||| .... .|||.
lfseefhdlpdPdiyrqrv.aretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmv
TRCFEKGREKCDQYWPV-DRVAMFYGDIKVQLIIDTHYHDWSISEFmVSRNC-ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHC
| | . || |||| . .. .| |||.|. | . .. | |. ||| . |.|| ||| ||.. ||...... . |.. ...|||
tkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsllvhc
SAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHL
||||||.| .|..| ....|.... ||.| .| .|..|...||||..| |.. .| | .. |
saGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntl
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 1332-1586 | 9.8e-68 | 223.1 | In-house | 20-276 (280) | alignment | ||
Range on Protein: 1332-1586
Range on HMM: 20-276/280.0
EFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQpvddDDGSDYINANYM----PGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
.||.| .. |.| |..| | .|||. .|||||. | ||. . .|||||||. |... .|.|||||..| ..||.| || .|. ||||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvklk....esetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml
TRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNC--ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHC
| |.|| || |||| . ||...|.. . . . . . |...... |.| . .. .. ||| |||. ......||. |.. .. .|..|||
ttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgkeePvvvhC
SAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
|||.||.| .|.|. |. | ... | . || || | .|||..|| . ...|.| |
saGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkvye
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 1329-1589 | 1.4e-67 | 222.9 | In-house | 20-280 (515) | alignment | ||
Range on Protein: 1329-1589
Range on HMM: 20-280/515.0
FSEEFEELKHVGRdQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLT
||||| .| . |. | .|||. |||||| .| ||. ..|. |||.|| |.|. .. . .| .|||.... ..|||. .. | .|.|.|
fseefhdlpgpni.ypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvt
RCFEKGREKCDQYWPV-DRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSA
. | . || .||| .. .| |||.|. . . .. | .. .|| . |||| ||| |||. .||...... . | |.|.||||
klkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpliihcsa
GVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKE
|||| | .|..| .. |..... ||.| .| .|..|...|||..|| |.. .| | ..
GvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrn
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1343-1600 | 1.7e-67 | 222.6 | In-house | 39-294 (315) | alignment | ||
Range on Protein: 1343-1600
Range on HMM: 39-294/315.0
QACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYW
. |. |. |||. ||..||.|| .| .. |..|||.|||...|.| .| .| .|||. .. ..|||. .| . ||||| |. ..|...||
hpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekyw
PVDrvAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRIL
| . . || | | .. . .. .... . | . . | . .|.|.||| |||. .|. ..| . ... .|.|||||||||.||||.|| .|
pdk..kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtnsvgaivvhcsaGvGrtGtfitldavl
QHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHA
.... . .|.. .. .|. |. |||. .|| |.. || . . .|. | |.
dqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqr
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 1330-1586 | 3.3e-66 | 218.4 | In-house | 14-270 (273) | alignment | ||
Range on Protein: 1330-1586
Range on HMM: 14-270/273.0
SEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQpvddDDGSdYINANYM--PGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
.|||.||... . |. .. |. |||. |.||||..| ||. |.|. ||||... | . |.|..|||| | ..||.| || ... |.|.
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklg....degg.yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv
TRCFEKGREKCDQYWPVD--RVAMFYGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDvIGTDMRPIIV
| |||. ||..|||. . . .. ..|.|. ............|. ||| . |..|..||| ||| ...|..||. | . || ||.|
tlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrr.lqtdagPivv
HCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
|||||.|||||.|..| .|. |.. .|. || .|. | .|||..||. ... .| ||.
hcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1309-1586 | 2e-65 | 215.6 | In-house | 2-284 (290) | alignment | ||
Range on Protein: 1309-1586
Range on HMM: 2-284/290.0
VHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDD-D-GSDYINANYMPGHNSPREFIVTQGPLH
. |..|.|. | . .| ..|. |. .... .. . |...|||.||..|| | |.|. .. | .|||| |. |.. ...|.||||..
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
STREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMfYGDIKVQLIIDTHYHDWSISEFMVSRNCE---SRIMRHFHFTTWPDFG-VPEPPQS
.| .||.. |. .. .||||| |.|..|| |||| ... || ....|. ...... . .. | . . .... ....|.|.. | |..| .
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqti
LVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
|. . . . . ..|.||||..||||..|.|.. ... .. .|.| .. .| . .|||.||| |.| .| |.
llvieemyktqrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyld
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 1352-1583 | 2.6e-65 | 215.1 | In-house | 19-262 (270) | alignment | ||
Range on Protein: 1352-1583
Range on HMM: 19-262/270.0
CNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPG-HNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVD---RV
.. ||...||| ..| .|.....|. . ||||||..| .......| ..||| .| ..|||| ||....||||.| ||||.||..||| . .|
rgkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv
AMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQ------SLVRFVRAFRDVIGTDM--RPIIVHCSAGVGRSGTFIALD
.. .|.||| . ... . . . . . .. |.| . ||...|||| |||. .. .|.. .|| | . |..|||||||||.||.||||
kledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlialD
RILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
... .... ||. |. ..||.|. .||. .|| ... ..
iavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 1349-1583 | 1.4e-64 | 212.9 | In-house | 24-266 (274) | alignment | ||
Range on Protein: 1349-1583
Range on HMM: 24-266/274.0
NLPCNRPKNRFTNILPYDHSRFKLQPVD-DDDGSDYINANYMPGHNS-PREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDR
... . |||...||| ..|| |.. . .|. |.||||||. | . . .. ||||| .| ..|||| .. ... |||||. |. ..|| .|.| ..
dvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdae
V---AMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG---TDMRPIIVHCSAGVGRSGTFIALDR
. |||.... .. .|.|. ..... ..| . |. .| ||| .|. ...|...|. .. . . |..||||||.|| | ||| .
dyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisi
ILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
....... ||...|| .| .| ||||..|| ||. |
avrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 1324-1589 | 1.2e-61 | 203.4 | In-house | 24-288 (297) | alignment | ||
Range on Protein: 1324-1589
Range on HMM: 24-288/297.0
DSDFrFSEEFEELKHVgRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSprEFIVTQGPLHSTREEFWRMCWESNSRA
..|. ||||| | . |. |. | .|.|..|||||| || ||. |.|| |||.|| ...| . ..| || | ..| ..||.| .. . .
htdv.fseeflclpea.niqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvst
IVMLTRCfEKGREKCDQYWPVDRVAMfYGDIKVQLIIDTHYHDWSISEFMVSRNC--ESRIMRHFHFTTWPDFGVPE--PPQSLVRFVRAFRDVIGTDMR
||||. ... .|| .||. . |. .||. |.| .. . . |. |... |... ..|. ||| |.. .||. .. |.. ..
ivmlndd.nerdkkcaryWsdkgvtt.fGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnae
-PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKE
|..|||.||||| | ....| .. .... . |||||.| .|.||...|||..|| ... .| .| ..
gPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsed
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1310-1587 | 1.4e-61 | 203.0 | In-house | 3-280 (287) | alignment | ||
Range on Protein: 1310-1587
Range on HMM: 3-280/287.0
HVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANL-PCNRPKNRFTNILPYDHSRFKLQpvddDDGSDYINANYMPGHNSPREFIVTQGPLHST
|. |.| . | .. |.. | |..|.... |. . |..|||.|.||..| | |. . ||||| .. |... ..||....|. .|
pvekfgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfnt
REEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVaMFYGDIKVQLIIDTHYHDWSISEFMVSRNC---ESRIMRHFHFTTWPDFG-VPEPPQSLV
.||.. .. | |||||.. |. .|.| |||| .. . .|. ...|. ....... . .. | .. . . .. ...|.|.. | |.|| .|.
arnfWkliddrnvtaivmlcqekendeevcyqyWpeeks.vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtill
RFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEG
. . .. .|.||||..||||..|.| . ... .. .|.| .. .| . .||| .|| | . .|. |.
vieemyktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleylds
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 1311-1596 | 7.8e-61 | 201.0 | In-house | 7-300 (325) | alignment | ||
Range on Protein: 1311-1596
Range on HMM: 7-300/325.0
VKDFSEHYRIMSADSDFRFSEEFEELKHVGrDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTRE
| .. || |. . |. ||. | .. .| | .| |. |||| |....|.|| |. .|| ||||||.|. . |. .| || .| .
vvnlvehvekkkaqdqdgfahefgllpsdd.giakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatin
EFWRMC--WEsnsRAIVMLTRCFEKGREKCDQYWPVD-RVAMFYGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVR
..||. |. ..|... ...| ..| .||| . . .| ..|.|. .. |. . | . . |.| .. |.. .|.|.||.. | .|.
dlWrlvldWr...csvvvvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlis
F---VRAFRDVIGT---DMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL-EGKEHLLADSL
. | | . . . ||.|||||||||.|.||.| .|... . ||||| | .||.| ||.| ||. |...| .. |. . |.
ilqlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssf
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 1329-1590 | 2.8e-58 | 192.0 | In-house | 17-282 (288) | alignment | ||
Range on Protein: 1329-1590
Range on HMM: 17-282/288.0
FSEEFEEL----KHVGRDQACSFANlpCNRPKNRFTNILPYDHSRFKLQpvddDDGSDYINANYMPGHN--SPrEFIVTQGPLHSTREEFWRMCWESNSR
. ..|.|| .. |..... |. .. |||...||||||.| ||. . ||||| .. . .| .||.||.||.|| .||.| .| |.
ldkkfkeleqkqdkearkrsiaiak..lyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcP.dfiatqaPlqstlnDFWlmvyeqkss
AIVMLTRCFEKGREKCDQYWPVDR-VAMFYGDIKVQLIIDTHYHDWSISEFMVSRNC--ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRD----VIG
||||. |.|..|.|.||| |. .. .||..| | .. . .. .. .. . . . ..| ..|.||..|||. |..|..|. . .. |
viVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqr
TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDY-VDIFGIVFAMRKERVFMVQTEQQYvciHQCLLAVLEGKEH
|..|||||||||.|.| . ... ..| . .|| .| .|..| ||||...|. .... |||| ..
ksktPlvvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeql...kfsyeavleaarr
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 1353-1582 | 2.6e-56 | 185.5 | In-house | 3-236 (237) | alignment | ||
Range on Protein: 1353-1582
Range on HMM: 3-236/237.0
NRPKNRFTNILPYDHSRFKLQPVDDDdgSDYINANYMPGHN-SPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFY
|. |||. || ||||| |. . ||||||.|. | . .|...| .|||| |. ..||.| |. . ||||| |. ..|| .||| |
nkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GDIKVQLIIDTHYHDWSISEFMVSRNC---ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG--TDMRPIIVHCSAGVGRSGTFIALDRILQHIH
| . | | . .. |... ...|.. | |.. ..||.||| |||. .|.|| . . .. | |.||||||||.| |. .| .|.. .
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
KSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
. |||. |... ..| ...||..||| ||| .|
ekkvvdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 1352-1584 | 9e-56 | 183.7 | In-house | 6-236 (239) | alignment | ||
Range on Protein: 1352-1584
Range on HMM: 6-236/239.0
CNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGH-NSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPvDRvAMF
|. |||..||. ||||| |. . .| ||||||.|. . ||. .| ||| . . .|||| |. ||||| | ..|| |||| | .
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.ds.tsk
YGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKS
| ...| | . |. | |..|. . | | . ..||| ||| |||. ... . | || ..||||||||.|.|. .| .|.. .|
ycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkq
DYVDIFGIVFAMRKERVFMVQTEQQYVCIHqclLAV
|||| | |.|..| .|||| .||| || |||
ktvdifnyvkairedrphmvqtseqyvfih...lav
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 1352-1582 | 1.2e-55 | 183.3 | In-house | 7-238 (239) | alignment | ||
Range on Protein: 1352-1582
Range on HMM: 7-238/239.0
CNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGH-NSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPvDRvAMF
|. |||..||. ||||| |. . .| ||||||.|. . ||. .| ||| . . .|||| |. ||||| | ..|| |||| | .
vnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywp.ds.tsk
YGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKS
| ...| | . |. | |..|. . | | . ..||| ||| |||. ... . | || ..||||||||.|.|. .| .|.. .|
ycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpgarpwvihcsagvgrtgaflvidamlrqakkq
DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
|||| | |.|..| .|||| .||| || ..|
ktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 1311-1609 | 5.1e-55 | 181.7 | In-house | 4-304 (439) | alignment | ||
Range on Protein: 1311-1609
Range on HMM: 4-304/439.0
VKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACS--FANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHST
..| || . . . |.|.||... . | || .| ...|||. .. ..||.| || . | ||||||. |. .. .| |||| . |
rdefqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkket
REEFWRMCWESNSRAIVMLTRCFEKGRekcdqYWPVDRvAMFYGDIKVQLIIDTHYHDWSISEFMVSRN----CESRIMRHFHFTTWPDFGVPEPPQSLV
..|||. .| .. ||||| .| . ||| | ..|||| |. . .. | | | . | . .||...||| || ..
tddfwrlviekktvtivmltnlvesyk.....ywpsda.evcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvl
RFVRAFRDVIG-TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL-EGKEHLLADSLELHAND
|.|| .. |..|||||||||.|| |||| |.... . ||| ||| .||.| |||. ||| |....| . |. .. | .. . |
dflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkkefna
GYEVTKI
|. |
gfstrdi
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 1342-1582 | 9.3e-55 | 180.3 | In-house | 31-287 (296) | alignment | ||
Range on Protein: 1342-1582
Range on HMM: 31-287/296.0
DQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGReKCDQY
| . || ||| ...|||. | |. .| .. |||||| |. .. ..|.|||..| ..| .||||. .. .. |.|.||. |. . .. .|
igdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsy
WPVDRvAMFYGDIKVQLIIDTHYHDWSISEFMVSRN------------CESRIMRHFHFTTWPD-FGVPEPPQSLVRFVRAFRDVIGT-----DMRPIIV
|| . ||.| |... .| . | .| . .. | ||...|..|.|. || ..|. ..| | ... . |..|
wpnks.keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvv
HCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
..| |..||| ..|.| |. ..| . ||.|. | .|..| .|.. ..| | . ||
vssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvll
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 1332-1582 | 3.1e-54 | 178.8 | In-house | 11-263 (283) | alignment | ||
Range on Protein: 1332-1582
Range on HMM: 11-263/283.0
EFEELKHVG-RDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDddgsDYINANYMP---GHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
.| ||... |. . | |..|||. .|.|.| | .|.. ||||| ..| .. ...|..|.||. |. .||.| .. . |||||
frevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivml
TRCFEKGREKCDQYWPvDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRN---CESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVH
|. | |.|| |||| | .. ||. | | .| . ..| |... | .. .. |. . | ..| . |||.| . ||.||
tklqedlrikCsqyWP.krGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgPivvh
CSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLL
||.|.||...|||. .... . ||.| .| ||..|. .||| .|| .|. |
CstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvl
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 1328-1586 | 1e-53 | 177.2 | In-house | 21-237 (392) | alignment | ||
Range on Protein: 1328-1586
Range on HMM: 21-237/392.0
RFSEEFEELKHVGRDQAcSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
|.||| .| . . |. . | .|||. |||||| .| ||. .|| |||.|| |.|. .. . .| .||| .. ..|||| .. | .|.|.
lffeefhdlpgpdiypq.tvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamv
TRCFEKGrekcdqywpvdrvamfygdikvqliidthyhdwsisefmvsRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSA
|. | . . | . |||| ||| .||. ||..|.. . | .|.|.||||
tklkegd.........................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpliihcsa
GVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
||||.| |..| .. | .|. ||.| .| .|..| .||||..|| |. ..| |
gvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledll
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 1380-1587 | 6.9e-53 | 175.3 | In-house | 3-227 (272) | alignment | ||
Range on Protein: 1380-1587
Range on HMM: 3-227/272.0
GSDYINANYMPGHNS---PREFIVTQGPLHSTREEFWRMcWESNSRAIVMLTRCFEKGREKCDQYWP-----------VDRVAMFYGDIKVQLIIDTHYH
|.||||....| .. |. .. ..|||. | ..|||. .| . ..||.|....|.||.|||.||| . ..||.. | |. ....
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DWSISEFMVS---RNCESRIMRHFHFTTWPDFGVPEPPqsLVRFVRAFRDvigtdMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVD--------IF
|. . |.... . |.| ..|.|.| |||.|||. . |........| .|..||||||..|.||..||...|. ..... || ..
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.....ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyle
GIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEG
..| .|. | .||||.||......||..|..
eaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 1330-1585 | 1.4e-52 | 173.6 | In-house | 26-296 (300) | alignment | ||
Range on Protein: 1330-1585
Range on HMM: 26-296/300.0
SEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDdGSDYINANYMPG--HNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
|.|.... | .| |.|| | .|||| ..|||...| .|.| .. ..|||| . . |..||.||||. | ..||.| ||.. . ||||
fteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivml
TRCFEKGREKCDQYWPVD---RVAMFYGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG--TDMR-
|. |.|.||. .|.| . . . .| ||. .. . . . . | | . |. .| ||| |||| ... . ... .. | ....
teeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseve
------PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
|..|||||||||.| | | ... ... . .|| .. .|. | ..||| || ... |. |
skeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 1330-1581 | 7.6e-51 | 167.6 | In-house | 13-273 (287) | alignment | ||
Range on Protein: 1330-1581
Range on HMM: 13-273/287.0
SEEFEELKHVGRDQACSF--ANLPCNRPKNRFTNILPYDHSRFKLQpVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
.|.. ||. . . | |. . |||....||.|..| | . . |||||||||..... .||..|||. .| .|||. .| .| .....
dkevdalkedsesstatfkaaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitm
TRCFEKGREKCDQYWPVDRVAMFYGDIKVQLI-IDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVI-----GTDMR
|| |..| || .||| .| | | | |. | .... . . |.|... ... .||| ... .|.||| .. | ....
treveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevG
PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCL
|..||...|.||||...|. ... . ||. .| .|. | .||. |. . . |
PlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyeal
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 1353-1588 | 2.2e-49 | 162.9 | In-house | 1-174 (182) | alignment | ||
Range on Protein: 1353-1588
Range on HMM: 1-174/182.0
NRPKNRFTNILPYDHSRfklqpvddddGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTrcfekgrekCDQYWPvdrvamfyg
|..|||...|||||||| ..||||||.. | ...||.||||| || ..|.|| .| . ..||.|| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
dikvqliidthyhdwsisefmvsrNCESRIMRHFHFTTWPDFGVPEpPQSLVRFVRAFRDvigtDMRPIIVHCSAGVGRSGTFIALDRILQHihksdYVD
. . | ..... |||.|||. ...|..|... .. . .|..|||||||||.||..|.. .... |.
........................ellerlgiqylylpwpDhgvpd.ldelldfieevle....eggpvlVHCsaGvgRtgtlvaaylmkkl.....gvs
IFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGK
.. .| .|. | ||.|..||. ....|| .|..|
leeavklvrsrRpgmvitpnqyfflqlallellllk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 1328-1581 | 1.2e-48 | 160.4 | In-house | 30-288 (297) | alignment | ||
Range on Protein: 1328-1581
Range on HMM: 30-288/297.0
RFSEEFEELKHVGRDQAC-SFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNsPRE--FIVTQGPLHSTREEFWRMCWESNSRAI
|...|.| |.. .... . |. . | ||| ...||||||| ||. ... |||||| . |. ||. .| ||||| || .||.| ||. . |
rlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhd.prapayiatqgplastvadfwqmvweqGvvvi
VMLTRCFEKGREKCDQYWPvDRVAMFYGDIKVQLIIDTH-YHDWSISEFMVS--RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPI
|.||| |.| ..|..||| | . |. .|.|. . .|. . | . .. |.| . ||| .||. ||| ..||. | | ||
vnltrleeegvkqckrywp.deGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscpi
IVHCSAGVGRSGTFIALDRILQHIHKS-DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCL
.||||.|.||.|..|..| .|... | .|| . .| .| .|.|..|. . ...
vvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltav
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 1329-1583 | 6.8e-48 | 157.7 | In-house | 13-267 (281) | alignment | ||
Range on Protein: 1329-1583
Range on HMM: 13-267/281.0
FSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQP-VDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVML
| .|| .| . |. | | | |||..|| | || .|. . . . .||| |||. | .|.|||| . || .|||| |. |. |||||
fkqefsnlpgdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivml
TRCFEKGREKCDQYWPVDR-VAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRdvigTDMRPIIVHCS
. | |||| .|.| . ... . . |. | . . . .| . |.|.. |. . |||. ||| . ... .| | . | ..|||
cqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkir....arstppvihcs
AGVGRSGTFIALDRILQHIHKS-DYVDIFGIVFAMRK-ERVFMVQTEQQYVCIHQCLLA
||||||||..|.. || || || || .| | ||| |||. | . ||
agvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 1380-1579 | 1e-46 | 154.1 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 1380-1579
Range on HMM: 1-164/174.0
GSDYINANYMPGHNSPREFIVTQGPLHstreeFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVdrvamfygdikvqliidthyhdwsisefmvSRNCE
|||||||... .. ....|..|||| ||.|..| .....|||....|.|..|| .||| |. .
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredl
SRIMRHFHFTTWPDFGVPEPPQsLVRFVRAFRDVIGT-DMRPIIVHCSAGVGRSGTFIALDRILQHIHkSDYVDIFGIVFAMRKERVFMVQTEQQYVCIH
.| ..... |||.|||. .. | .||.. .... . .|..|||||||||.||..|....|.... ...||.. .| ..|. | ||||..|| ..
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
Q
.
y
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 1323-1586 | 4.5e-46 | 151.9 | In-house | 14-294 (301) | alignment | ||
Range on Protein: 1323-1586
Range on HMM: 14-294/301.0
ADSdfrFSEEFEELKHvGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDD--DDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESN
... |.|...|||. |.|. |. |.. ||| || .||. |. |.| . .||||.|. | .. ..||..|||...| .|||. |.
snk...feeqykelke.gedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqek
SRAIVMLTRCFEKGREKCDQYWPVDRV-AMFYGDIKVQLIIDTHYHDWSISE-----------------FMVSRNCESRIMRHFHFTTWPDFGV-PEPPQ
.|||.| |. ..|| |||| . .| ..|.|. .. | |. | . | |... .|. . .. | ||. || .||
pvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprt
SLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
| . |..||||..|.|||...... | ||.|... |.|. . .|.| .||. |.. . |.
vLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylq
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 1342-1587 | 8.8e-45 | 149.1 | In-house | 35-282 (314) | alignment | ||
Range on Protein: 1342-1587
Range on HMM: 35-282/314.0
DQACSFANLPCNRPKNRFTNILPYDhSRFKLqPVDDDDGSDYINANYMPGHnspREFIVTQGPLHSTREEF----------WRMC--WESNSRAIVM---
.. . .|.|..|| |||...|||.| .| .| | . .|||||||.|. |. . ||.||||| | . | ||| .. |.| |||
eltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrd
------------------LTRCFEKGrekcdQYWPVDRVAMFYgdikvqliidthyhdwsiSEFMVSRNCESRIMRHFHFtTWPDFGVPePPQSLVRFVR
|... ..| .... ..... .| .| ........ .||...| ... . .|..
evladelsrLdaAlgKtpllildgng.....neptaadlellk..................eelydpelferlgikylri.pvpDgsap.lledfdefle
AFRDVigTDMRPIIVHCSAGVGRSGTFIALDRILQHIHksdyVDIFGIVFAMRKERV-----FMVQTEQQYVCIHQCLLAVLEG
..... . .|..|||.||.||.|||.... .. . . |.. .. .|. | .... .||. |...|| |.
fieea..dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyefilealleylkf
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 1355-1583 | 1.1e-44 | 147.2 | In-house | 58-281 (290) | alignment | ||
Range on Protein: 1355-1583
Range on HMM: 58-281/290.0
PKNRFTNILPYDHSRFKLQpvDDDDGsDYINANYMPGHNSPreFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVD-RVAMFYGD
|||. .. | .| |. | || ||. |||. | ... ||.|||.|..| ..||| . . ||||| .|.|. ||.||.| .. .|.
kknrykdvvcndktrvilk..dGydG.dyvhanyvkGlkam..filtqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
IKVQLIIDTHYHDWSISEFMVSR---NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGtdmrPIIVHCSAGVGRSGTFIALDRILQHIHKSDY
| | ... . | . | . . ...|.. .||| |. .|.| .|. | . | |..||||||.||.|||.|.. || . .
itvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrkasG....pvvvhcsaGiGrtGtfvaievglqilldGke
VDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
.|. ..| |.|. |. || . ||. . . ||
ldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 1331-1584 | 2.3e-44 | 146.6 | In-house | 20-276 (307) | alignment | ||
Range on Protein: 1331-1584
Range on HMM: 20-276/307.0
EEFEELKHVGRDqACSFANLPCNRPKNRFTNILPYDHSRFKLQpvDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRC
.||..| . . . . . .| |||.... |..| .. | |||| |||. |. ||..||||..|. .|| |. . . ...|| ..
defrvlakktpe.gvtveafsantdknryqdvkcqdkgrivvk..fdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckv
FEKGREKCDQYWPVDRV-AMFYGDIKVQLII-----DTHYHD---WSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRdvigTDMRPI
| .. ||.||||... . .|. . . .. | .... | .|| ..|. .. ||| |||. . . .. | | | |.
ielakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavr....ydtnpv
IVHCSAGVGRSGTFIALDRILQHI-HKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAV
.|||||||||||| .|. . . . . |. .| .|..| . .||| ||. .|. ||
vvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 1373-1585 | 3.5e-43 | 142.7 | In-house | 4-173 (176) | alignment | ||
Range on Protein: 1373-1585
Range on HMM: 4-173/176.0
QPVDDDDGSDYINANYMPGHnsprEFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVdrvA---MFygdikvqliidthyhdwsi
.. .| ..||||||.. |. .|.|||||..| ..|..| .| . .|.|.|| ..|.|| ||..|||. .
rllgldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpe...leklgi...................
sefmvsrncesrimrHFHFTTWPDFGVPEPpQSLVRFVRAFRDVIGTDmRPIIVHCSAGVGRSGTFIALDrilqHIHKSDYVDIFGIVFAMRKERV-FMV
..... |||.|||. . | ..... |... . .|..||||||.||.||..|.. .... .... .. .|. | ..|
...............qylhlpwpDhgvpdl.elllellefirealkeg.gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgav
QTEQQYVCIHQCLLAVL
||..|| .....| .|
qtpeQyrflyefellll
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 1347-1586 | 4e-43 | 142.5 | In-house | 40-272 (288) | alignment | ||
Range on Protein: 1347-1586
Range on HMM: 40-272/288.0
FANLPCnrpKNRFTNILPYDHSRFKLQpvddDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVD-
| . |. ..|..|. | .| ||. || ||.|| .. .. .| .| .| ||..| ||.|.| ||. . ||||.. |||.|| ..|.|.
fianpt...rdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPskl
----RVAMFYGDIKVQLiiDTHYHDWSISEFMVSRNCESRI-MRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVigtdMRPIIVHCSAGVGRSGTFIALDR
|. . ..|.. . . ..| . .|.. | .. ... |. |.| |||| .| .|.. .... .||.||.||||||.||.|
Gekarigrlctvvkkkr..adidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlksl....qkPivvhssaGvGrtgtlilili
ILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLE
.|. . .|.. | .. .|.|| .|||.||. .|.|.| |
aleslrlddflgirsllaklreerfkaiqtemqylyvhrcvleell
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 1378-1579 | 1e-42 | 141.1 | In-house | 2-155 (172) | alignment | ||
Range on Protein: 1378-1579
Range on HMM: 2-155/172.0
DDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCfekgrekcdqywpvdrvamfygdikvqliidthyhdwsisefMVSRN
|.|||||||.|.... |..||.||||| .| ..||||..| . ..||.||.. .. .
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpe
CESRIMRHFHFTTWPDFGVPePPQSLVRFVRAFRD-VIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIhksdyvDIFGIVFAMRKERVFMVQTEQQYVC
...| ..... |||.||| ... | .|.. .. .. . |..|||||||||.||..|.. .|... ... .| .|. | .||...|| .
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylmllgl......sleeavalvrekRpgavqnpsqyrf
IHQ
...
lyy
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 1324-1583 | 1.1e-40 | 134.4 | In-house | 3-257 (267) | alignment | ||
Range on Protein: 1324-1583
Range on HMM: 3-257/267.0
DSDFRFSEEFEELKHVGRDQAC-SFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDdgsdYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSR
|.. . .|||..|.. ... | |. .||. . ||||..| |. ... |||| |. |.. . |||||.||. | .|. . . .
deeceiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvp
AIVMLTRCFEkgrEKCDQYWPVD-RVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNCES-RIMRHFHFTTWpDFGVPEPPQSLVRFVRAFRDVIGTDMRP
||.||. |. .. ..|| | | |. |. .. |. | . . . || . . ... | . . . | | .. . ||
vivlltkvft...dnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahnvtlyyykkw.nintnnkpylkplfgilaknqlengnrP
IIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
..|.||.||||||||. .| |. . . . .||| . .|. |. .|.| ..|. ||. |
lvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 1330-1538 | 2.8e-40 | 133.3 | In-house | 24-249 (418) | alignment | ||
Range on Protein: 1330-1538
Range on HMM: 24-249/418.0
SEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHnSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTR
||| |. | . | |||.||||| .|.| .|. ..| .|||||||||. | |..||.||||| | .|||| || | ||||.|
keefrlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidga.ypkqfictqgplpntiadfwrmvwenrcriivmlsr
CFEKGREKCDQYWPVDR----VAM------FYGDIKVQLI--IDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAF----RDV
|. | |||.||| . ... .| |.|. |. .. . .. . |.| . .... |||. .|. | . ..... ..
esencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqi
IGTDMR--PIIVHCSAGVGRSGTFIAL
| . | ||||||||||||.||| .
ipssdrnvpiivhcsagvgrtgtfcta
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 1388-1579 | 1.4e-38 | 127.3 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 1388-1579
Range on HMM: 1-144/152.0
YMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWpvdrvamfygdikvqliidthyhdwsisefmvsrncesrimrHFH
...|.. |.||| ||||. | ..|||| .| . ..|||||...|.|..||.||. ...
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qyl
FTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILqhihksDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQ
.. |||.|||. .| | .... . . . |..|||||||||.||..|.. .| |... .| .|. | .|....|. ...
hlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 1352-1585 | 2.8e-37 | 123.0 | In-house | 54-289 (305) | alignment | ||
Range on Protein: 1352-1585
Range on HMM: 54-289/305.0
CNRPKNRFTNILPYDHSRFKLqpvDDDDGSDYINANYMPGHNSP-REFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRV--A
. |||.... |.| || |. |||| |||. | . ||..|||| | .||| | . . |||| . | |. || ||||. .
iaitknryqdvpcqdqsavkl...dkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgekl
MFYGDIKVQLIIDTHYHD----WSISEFMVSRNCES-RIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRdviGTdMRPIIVHCSAGVGRSGTFIALDRILQ
. . | |. . .. . |. . .. . . .||...| ||| ||| . . .. | | |. ||.||||||.||.|| .|.. ||.
elksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair...gs.kvpivvhcsagigrtgtivaieyile
HIHKSDYV-DIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
.| . . . .| |.| .| | .|.. ||. ||. .| .
kiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 1353-1592 | 5.3e-37 | 122.2 | In-house | 48-294 (305) | alignment | ||
Range on Protein: 1353-1592
Range on HMM: 48-294/305.0
NRPKNRFTNILPYDHSRFKLQPVDdddGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMF-Y
.. |||. .. |. | ||.. .|| |||. |. || || ||. | .|| ||.. . || || ||| .|| .|.. . .. .
eagknrykdvgcldnnrvklegpw...pheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlef
--GDIKVQLIIDT----HYHDW---SI--SEFMVS-RNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGtdmrPIIVHCSAGVGRSGTFIALD
.. |... ... .... . ..... ...| . |.|. ||| ||| .... .. | | ||.||||||.||.|. . |.
eekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpskg....pivvhcsagigrtgsvvmle
RILQHIHKSDYVDI-FGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLL
||. . . .. |. .|..| .||..||. .|| .| .. |. |
yildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyfrkkklld
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1341-1507 | 5.4e-35 | 115.7 | In-house | 21-190 (297) | alignment | ||
Range on Protein: 1341-1507
Range on HMM: 21-190/297.0
RDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDddDGSDYINANYM--PGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKC
| .. | |. . |||...|| .| .| ||. | ..|||||.|. | ... .|..||||..| ..||.. .| . |.|||... | ||.||
rgesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkc
DQYWP-VDRVAMFYGDIKVQLIIDT--HYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFV
||| |. . ||. |. . .| ... ..|. . ||| .|| | .||| ||| . ||||
apywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfq
|
|||||||||
PTPc_DSPc_SM00012 | 1483-1582 | 1.8e-34 | 113.5 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 1483-1582
Range on HMM: 2-104/105.0
MRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDM--RPIIVHCSAGVGRSGTFIALDRILQHIHKS-DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQ
..|.|.|.|||.||||...|.....||.... |..|||||||||.|||.||| .||...|. . |||| || ..||.| |||||.||. ...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
CLL
.||
all
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 1381-1581 | 2.5e-34 | 113.4 | In-house | 3-149 (151) | alignment | ||
Range on Protein: 1381-1581
Range on HMM: 3-149/151.0
SDYINANYMPGHnspreFIVTQGPlhstREEFWRMCWESNSRAIVMLTRCFEKGreKCDQYWPVDRvamfygdikvqliidthyhdwsisefmvsrnces
|||||..|. |. .....|| ..|... .| . ..||.|. .| | .| .|.|
sdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg..................................
RIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDvigTDMRPIIVHCSAGVGRSGTFIALDRILQHihksdyVDIFGIVFAMRKERVFMVQTEQQYVCIHQC
. .|.... |||.|.|. ......|.....| .. |..||||||.||.||..||...|.. |... .. .|. | .||..||.......
ievlhipildwpdpglplsfdavleflellld...kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfa
L
|
l
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 1364-1582 | 4.1e-34 | 113.1 | In-house | 1-168 (178) | alignment | ||
Range on Protein: 1364-1582
Range on HMM: 1-168/178.0
PYDHSRFKLQPVDDDDGSDYINANYMPGHnspreFIVTQGPLhstrEEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVamfygdikvqliidth
|.|..|..|... . .||||||... .. ..... | ...... .| . ..||.|| .| |..|||.||| .
pldrtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag................
yhdwsisefmvsrncesrimRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHihksdYVDIFGIVFAMRKE
..... .||.|||. .. . .||.. .... .. .|..||||||||||||..|.. .... .... .. .|.
....................iqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvrer
RVfMVQTEQQYVCIHQCLL
| .|... |. .... |
Rp.ivpnpgqlrqLyefel
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 1342-1590 | 1.2e-33 | 111.1 | In-house | 41-295 (310) | alignment | ||
Range on Protein: 1342-1590
Range on HMM: 41-295/310.0
DQACSFANLPCNRPKNRFTNILPYDHSRFKLQpVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQY
|.. .. . |||..... | || ||. .| ||| |||. ||..|||| | .|||| .. . .|..| . |.|| || |
dssltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgy
WPVDRVAMFYGDIKVQLIIDThYHDWSISEFMVS------------RNCESRIMRHFHFTTWPDFGVPEPPQSLVRfvraFRDVIGTDMRPIIVHCSAGV
|| |. || |.| . .. ... | .. |. | . . .. ||| |||. | | . | .||||||.
wpslgvtetygcirvtnlses.seefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp....qrllaqvrhgpcvvhcsagk
GRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEH
.| .. .||. ...... ..||. .. ..|.|. .||| ||. |.. .. |...
drlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvriifargete
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 1381-1574 | 1e-31 | 104.8 | In-house | 75-270 (301) | alignment | ||
Range on Protein: 1381-1574
Range on HMM: 75-270/301.0
SDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMF---YGDIKV---QLIIDTHYHDWSISEFMV
| ||..| . |. ||.|||||..|.|.|| |. . ||||.. || |||..| ||. . .||. .||.. . . ..
rvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtleveds
SRNCESRIMRHFHFTTWPDFGVPeppQSLVRFVrAFRDVIGTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQY
... ..| . |. ...|.| ||| .| . . ... .||.||||||.||| .||. . . .... ... . .|..| |||..|
tgkfatrtvthyqysewtdrgvP...kshaelf.dlmelvkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1331-1507 | 7.7e-31 | 101.9 | In-house | 6-187 (319) | alignment | ||
Range on Protein: 1331-1507
Range on HMM: 6-187/319.0
EEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHN-SPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTR
. .||.... . | . . . ..|.|. |..| ..| || . ||| . |..|.|. |.. .| .| .| .| .. .|||. || .|| || ||
dvaeefrdlPqliaradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltd
CFEKGREKCDQYWPVDRV---AMFYGDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFtTWPDFGVPEPPQSLVRFV
.|.| ..| .|.| ||||.| | . . || ... | . ||| . |. . |.. .|| ...|. .
lselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliaml
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 1354-1589 | 3.3e-30 | 99.9 | In-house | 44-280 (312) | alignment | ||
Range on Protein: 1354-1589
Range on HMM: 44-280/312.0
RPKNRFTNILPYDHSRFKLQpvddDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPvDRVA-----
. ||. || .| || | | || ||.. | |..|||||..| ||... | .|..|. | | ||| .| | |.
kdlnrypniqcwdrgrftla....gdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyis.divgfvdle
--MFYGDIKVQLIIDTHYHDW---SISEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRdvigTDMRPIIVHCSAGVGRSGTFIALDRI--
| . .. | . .| . .| . . |. ...||| |.|. .. |.. | . | .|.| ||||||||.||.. .. .
dhrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavk....kdkkpviahcsagvgrtgtlaliesmia
-LQHIHKSDYVDIFgivFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKE
|.| | . |.| .||.| |.. ||| .|.| .| |
alrhprkqnvkdsf...vllrkdrarsvrvfpqyvyalrcvleflyskg
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 1344-1585 | 6.3e-28 | 92.5 | In-house | 26-270 (285) | alignment | ||
Range on Protein: 1344-1585
Range on HMM: 26-270/285.0
ACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDdddgSDYINANY--MPGHNSpREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQY
|... .| ||.... . .| |. | ||| |.. |||.. .| ||||| | .||.| .. . ..|| || | ||| |
nctytayeanpdlnryadvrcieetrvvlknhd....rdyihaswmrmpgkdq.styittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcaly
WPVDR--VAMF------YGDIKVQLIIDTHYHDWSISEFMvSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIgTDMRPIIVHCSAGVGRSG
.| | | . | . | | . .. . . | | | . ||| || . .. . . . | .|| |||||||||.
ypeklgevvkfgkyeitlteckeeaiagtilnaltvinte.dasseplymnhvqvpwwpdqlapedarpmielykwvkkvn.pkekpicvhcsagvgrta
TFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
||. .| .| . .... || || |. ||. |.. .. |. .
tfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_egg_pd | Subfamily egg | 1353-1583 | 7.7e-25 | 82.2 | In-house | 40-268 (307) | alignment | ||
Range on Protein: 1353-1583
Range on HMM: 40-268/307.0
NRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKgrEKCDQYWPV---DRVAM
|. | | . | || ||. |.| ||.. |. |||..| || | ..|||| .. . . ||||| | |.|. ||| | . .
nlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywpkaesdslvt
FYGDIKVQLIIDTHYHD--WSISEF-MVSRNCESRIMRHFHFtTWPDFGVPEPPqslVRFVRAFRDVigtdMRPIIVHCSAGVGRSGTFIALDRILQHIH
| .... . . | . .... .| . | | . |. . . | .| .| |.. .|..|.. || ...|..|.. | ..
vpGslrienlkvdskadplfrvtklklvGgddeerflehwqg.dvnnssdvysp...lrvlrklrnl....skpvvvqdilGvskaatlvaieiallsll
KSDY--VDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
. . | .|..| . |.. .|. ... .|
rGpitkslvlravvflrlrrrlsvesvllylfvyrlvlf
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1356-1446 | 4.2e-24 | 79.9 | In-house | 50-154 (350) | alignment | ||
Range on Protein: 1356-1446
Range on HMM: 50-154/350.0
KNRFTNILPYDHSRFKLQ----PVD----DDDGSDYINANYMPGH------NSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQY
|||..|||||.||| ||. . | ..|||||||. |. .| ||.|| || ..|.... . . . |..|| .| ..|||..|
knrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyrY
WPVDR
|.
Wqegs
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 1462-1582 | 6.6e-24 | 79.6 | In-house | 36-140 (145) | alignment | ||
Range on Protein: 1462-1582
Range on HMM: 36-140/145.0
ThyhdwsisefMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDmRPIIVHCSAGVGRSGTFIALDRILQhihksDYVDIFGIVFAMR
. .. ..| ..... |||.|||. .. | .|... .... . .|..|||||||||.||..|.. .|. |... .. .|
l..........tselellerlgiqylylpwpDhgvpdllellleflefieealkeg.gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleealelvr
KERVFMVQTEQQYVCIHQCLL
. | ..|....|. .....|
sqrpgavpnpgqlrflyefel
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1477-1594 | 1.4e-22 | 74.7 | In-house | 85-204 (440) | alignment | ||
Range on Protein: 1477-1594
Range on HMM: 85-204/440.0
NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVI-GTDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYV
||| ....|. ||| |||. ...... . . |..||||||.||.| ||.| ||.. ..|| .||| .. .||..| |||| .||.
giesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqya
CIHQCLLAVLE-GKEHLLAD
.|...| | | .| |
fvheavlegllcgdtliled
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 1478-1579 | 1.4e-22 | 75.4 | In-house | 44-139 (144) | alignment | ||
Range on Protein: 1478-1579
Range on HMM: 44-139/144.0
CESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTDmRPIIVHCSAGVGRSGTFIALDRILqhihKSDyVDIFGIVFAMRKERVFMVQTEQQYVCI
.. | ..... |||.|||. .. | .|........ . .|..|||||||||.||..|..... | . .... .. .|. | ..|....|. .
fleregiqylhlpwpDhgvpdllellleflefieealeeg.gpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpgqlrfL
HQ
..
le
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 1392-1579 | 2.2e-21 | 71.0 | In-house | 1-198 (199) | alignment | ||
Range on Protein: 1392-1579
Range on HMM: 1-198/199.0
HNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCfEKGRE-KCDQYWPVDRV-AMFYGDIKVQLIIDTHYHDWSISEFMVSRNC----ESRIMRH
|.. | .|.|| ||. | .||.| ||. | |||. .| .| |||. . || . | | |..|. .... |. .| . |
hkgqrryiatqhplretmadfwqmvwetgsghivmvndd.qknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreish
FHFTTWPDFGVPEPpQSLVRFVRAFRDVIGT----DMRPIIVHCSAGVGRSGTFIALDRILQH--IHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQ
. ||.| . |. .| || | |.| |.||||| | | .| |.||| .. |. ||.| . .|. |. .. . |.| |.|
yqftswkekttpnv.alfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 1396-1579 | 3.9e-21 | 70.1 | In-house | 4-197 (198) | alignment | ||
Range on Protein: 1396-1579
Range on HMM: 4-197/198.0
REFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCfEKGRE-KCDQYWPVDRV-AMFYGDIKVQLIIDTHYHDWSISEFMVSRNC----ESRIMRHFHFT
| .|.|| ||. | .||.| ||. | |||. .| .| |||. . || . | | |..|. .... |. .| . |. ||
rryiatqhplretladfwqmvwetgsghivmvndd.qknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
TWPDFGVPEPpQSLVRFVRAFRDVIGT----DMRPIIVHCSAGVGRSGTFIALDRILQH--IHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQ
.| . |. .| || | |.| |.||||| | | .| |.||| .. |. ||.| . .|. |. .. . |.| |.|
swkekttpnv.alfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 1352-1584 | 1.9e-18 | 60.9 | In-house | 50-284 (302) | alignment | ||
Range on Protein: 1352-1584
Range on HMM: 50-284/302.0
CNRPKNRFTNILPYDHSRFKLQPVDDddgsDYINANYMPGHNSPREFIVTQGPLHSTR---EEFWRMCWESNSRAIVMLTRCFEKGReKCDQYWP-----
| ||. ... .|. . ||. | .|.|| . . |. |..| | .. |||||| .. . .|.| . | . ....|
knlkknqsedvpildsnlvkleaepd....syvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpkksgd
-VDRVAMFYGDIKVQLIIDTHyHDWSIsEFMVSRNCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAF-RDVIGTDMRpIIVHCSAGVGRSGTFIALDRI
.. .|| ||. ... . ..| | . .| .. ..| |.. ||. .|.. . | .| . ... |.|| |.|..|
ykeygkmfvNnrkVekaeeek.tryvi.EvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikaden.tvivSknGaGRagafltlava
LQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAV
.....|.. . | || ..|..| .|.. .||| .. .||
veklqkgkepnikeivksiRsqRpravdslkQyvslyiallly
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 1477-1583 | 2.8e-18 | 60.8 | In-house | 211-342 (350) | alignment | ||
Range on Protein: 1477-1583
Range on HMM: 211-342/350.0
NCESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGT----------DMRPIIVHCSAGVGRSGTFIALDRILQ----------HIHKSDYVD----
.. .. .... |.| .. |.|... . |.| . ||.||||||||| ||...|| .|. . .|.|.
asdPyvvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrD
-IFGIVFAMRKERVFMVQTEQQYVCIHQCLLA
|. || .|| |. |||. .|.. |...||
lisiivnelrkqrismvqnldqfifiYeallf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 1402-1585 | 1.3e-17 | 58.2 | In-house | 97-288 (302) | alignment | ||
Range on Protein: 1402-1585
Range on HMM: 97-288/302.0
QGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVD-RVAMFYGDIKVQLI-IDTHYHDW------SIS--EFMVSRNC--ESRIMRHFHFT
| .||.| .| . . | .| |. |.. .|| .|. . . . .| |. . ..|. ... . |. .. . . ..|.
ivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafs
TWPDFGVPEPPQSLVRFVRaFRDVIGtdmRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
.||| | |. ... . .. | . . ..|||||||||.||..|. .| | . |. || .|. | ||.||| . . |. |
awpdhGapkeaytaldilk.fcesyk...knvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvtkgl
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 1381-1581 | 6.5e-16 | 53.3 | In-house | 46-255 (290) | alignment | ||
Range on Protein: 1381-1581
Range on HMM: 46-255/290.0
SDYINANYMPGHNSpREFIVTQGPLH-------STREEFWRMCWESNSRAIVMLTRCFEKGRE----KCDQYWPVDRV-AMFYGDIKVQLIIDTHYHDWS
.||| ||.. | ..|.|| |.. || |.|| | . ... .||| || .. | .| | . .....|. . |
ddyiHAnrvtcpng.lrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpesvgeelkfkgltvkCkskekeddve
ISEFMVSRNCE-SRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRdvigTDMRPIIVHCSAGVGRSGTFIALDRILQHIH-KSDYVDIFGIVFAMRKERVF
. | .| . | . | . | . |.| ...|. .. . . |.|||| |. || .. |.. | | .|. | . .. |.||.|
tRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk....asktpvivHcvdGiSrsAalaaiilgyQkiaetsgsvkledvlkalrkqral
MVQTEQQYVCIHQCL
........ . .
aitsalelafvdagi
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 1352-1581 | 1.6e-15 | 51.6 | In-house | 46-275 (303) | alignment | ||
Range on Protein: 1352-1581
Range on HMM: 46-275/303.0
CNRPKNRFTNILPYDHSRFKLQpvdDddgSDYINANYMPgHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFY
| ||||.... |||. || | | || |.|. .| . |.|| || | .||.| | . . ...| | . | .| .. . .
knmdknrfvdvicldhskvkls...d...ssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkf
GD--IKVQLIIDTH-YHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEP-PQSLVRFVRAFRDVIG--TDMRPIIVHCSAGVGRSGTFIALDRILQHI
. |.| . . |.. || .. |. .|| .| .|. . . |. .| .| . .|.||.||| .. .
eersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlsl
HKS-DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCL
|. .|. . .|. |. || |. .. |
hseqasldlvkclenvrngrlhavqnlsqfsvvytll
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 1408-1548 | 2.1e-15 | 51.5 | In-house | 40-182 (255) | alignment | ||
Range on Protein: 1408-1548
Range on HMM: 40-182/255.0
TREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVA-MFYGDIKVQL---IIDTHYHDWSISEFMvSRNCESRIMRHFHFTTWPDFGVPEPPQSL
| ..|... ... .|||. |.|.|||..|.|... . . |..| . | . | . .. . . ..|.... |.. || .. .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstl.gekkkthtvkhysykGWieknaPelarei
VRFVRAFRDvigtdMRPIIVHCSAGVGRSGTFIALDRILQHI----HKS
... || ....||||.|.||| .|. . . |.. ...
lnilkvvrd.....sksvvvhCstGiGrsaafvlaelvyqkmirsldtt
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 1522-1585 | 2.8e-15 | 50.5 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 1522-1585
Range on HMM: 2-65/69.0
IVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
.||||.| ||.|||||. . | |||| | ||| | || |..|. || | |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
fn3 | Fibronectin type III domain | 902-975 | 3.3e-15 | 49.2 | Pfam-A | 2-79 (85) | alignment | ||
Range on Protein: 902-975
Range on HMM: 2-79/85.0
PISDLKAIQVAAREITLHWTAP---AGEYTDFELQYLSADEEAPQLLQNVTKNT-EITLQGLRPYHNYTFTVVVRSGS
....|....| ....||.|..| |..| .|..| ..... . ..|...| . ||.||.|. .|.|.| ..|
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavnga
|
|||||||||
subfamily_eak_pd | Subfamily eak | 1357-1512 | 8.4e-15 | 49.0 | In-house | 56-209 (332) | alignment | ||
Range on Protein: 1357-1512
Range on HMM: 56-209/332.0
NrFTNILPYDHSRFKLQPVDDDdGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDR-VAMFYGDIK
| .|.|||. .| . . |||| . . |..|.| . .. ||.| | .| |||.| |.. || |.|.| . . .| ..
n.vvkivpydrylvrltssqln.rlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGild
VQLIIDTHYHDWSISEFMVSRNCESRIMRHFHFTTWPDFGVPEPpQSLVRFVRAFRD
|. . ...|. |. . |... | .. .| . .. . .. ..
verkefvkrniletrllelskGnethrvlhykvfGwtettlpky.edflalrkvmke
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 1522-1585 | 1.6e-14 | 48.0 | In-house | 1-64 (69) | alignment | ||
Range on Protein: 1522-1585
Range on HMM: 1-64/69.0
IVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVL
.||||.| ||.|||||. . | |||| | ||| | || | .|. ||. | |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 1405-1547 | 8e-14 | 46.2 | In-house | 43-187 (263) | alignment | ||
Range on Protein: 1405-1547
Range on HMM: 43-187/263.0
LHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVA-MFYGDIKVQLII---DTHYHDWSISEFMVSrNCESRIMRHFHFTTWPDFGVPEPP
| | ..|... ... .|||. |.|.|||..|.|... . . ...| |. . . . . . . ..|. .. |.. || .
lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlge.KkkthtvkhysykgWiekndpela
QSLVRFVRAFRDvigtdMRPIIVHCSAGVGRSGTFIALDRILQHI----HK
.. .. ... |. ....||||.|.||| | . . |.. ..
reilnilkvarn.....skslvvhcstGiGrsaafsvaElvyqkmirsldt
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1356-1443 | 8.4e-14 | 45.6 | In-house | 51-154 (349) | alignment | ||
Range on Protein: 1356-1443
Range on HMM: 51-154/349.0
KNRFTNILPYDHSRFKLQPVD-----------DDD---GSDYINANYM--PGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCD
|||. .||||.||| ||. . | |||||||. . . . .| || || || ..|... . . .. |. .|.. ||||
knrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcd
QYWP
.||
iywq
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 1344-1502 | 5.1e-13 | 42.3 | In-house | 18-160 (169) | alignment | ||
Range on Protein: 1344-1502
Range on HMM: 18-160/169.0
ACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINAnympghnsprefivtqgplhstreefwRMCWESNSRAIVMLTRCFEKGR---EKCD-
.|.| || ||| . | | | ||| | .| ||||||| || ||.|. ||.| . .| || |
nnfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddknnfwpekedy
QYWPVDRVAMFYGDIKVQL----IIDTHYHDWSISEFMVSRNCESRIM---RHFHFTTWPDFGVPEPPQS
| | . .| | |. . . || . .. . . .|..|||. |||. |
qlhpavilgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpqspvh
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 1345-1502 | 7.5e-13 | 41.6 | In-house | 18-159 (169) | alignment | ||
Range on Protein: 1345-1502
Range on HMM: 18-159/169.0
CSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINAnympghnsprefivtqgplhstreefwRMCWESNSRAIVMLTRCFEKGR---EKCD-Q
.|.| || ||| . | | | ||| | .| ||||||| || ||.|. ||.| . .| || | |
nfmaeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddknnfwpekedyq
YWPVDRVAMFYGDIK---VQLII-DTHYHDWSISEFMVSRNCESRIMR---HFHFTTWPDFGVPEPPQS
| . .| | . . .| . . .| . .. . . .|..|||. |||. |
lhpavilGewytdslyvrtdkvhpntsgveglfevslvihsydddvteqlsllhystwpqngvpqspvh
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 1518-1581 | 7.9e-13 | 42.7 | In-house | 247-311 (319) | alignment | ||
Range on Protein: 1518-1581
Range on HMM: 247-311/319.0
MRPIIVHCSAGVGRSGTFIALDRILQHIHKS-DYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCL
|..|||| ||||.|. || | .... .| ||| .|. .|..| |.| .|| |.. |
qGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
|||||||||
fn3 | Fibronectin type III domain | 1013-1092 | 1.6e-12 | 40.5 | Pfam-A | 6-84 (85) | alignment | ||
Range on Protein: 1013-1092
Range on HMM: 6-84/85.0
FQPSDVQPGEVTFEWSLEPaEQHGPIDYFRITCQNADDAADVSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALGYGAE
.. |.|.. ..|..|| . ...|||............ . .. | ..|. .. || || .| ||.|| .. |.| |
lsvsevtstsltlsWsppk.dgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngagegpe
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 1307-1403 | 1.6e-12 | 41.4 | In-house | 3-95 (95) | alignment | ||
Range on Protein: 1307-1403
Range on HMM: 3-95/95.0
RPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGrDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDddgSDYINANYMPGHNSPREFIVTQG
.|.|| | | | ..|| | .|| . . . .| ||||| ||.||| .| | | |||||| .. |. .| .||
kpihvsvfhshvlemhsnsdqefdnefksismts.gapytvgsseanipknrflnifpydatrvvlttkrd...sdyinacfvdgyarkncyiaaqg
|
|||||||||
fn3 | Fibronectin type III domain | 247-326 | 2e-12 | 40.3 | Pfam-A | 3-80 (85) | alignment | ||
Range on Protein: 247-326
Range on HMM: 3-80/85.0
PGKFIVWFRNETTLLVLWQPPF-PAGIYTHYRVSITPDDAIQsvlyVEREGEPPGPA-QAAFKGLVPGREYNISVQTVSEDE
|. . | ...|.| . |.||. . | .|.|.| ... . ...| |... .. ..|| ||.||...||.|...
PenlsvsevtstsltlsWsppkdgggpitgYeveyrekggge....ewkeftvprtttsvtltgLkpgteYefrVqavngag
|
|||||||||
fn3 | Fibronectin type III domain | 719-790 | 2.6e-12 | 39.9 | Pfam-A | 11-79 (85) | alignment | ||
Range on Protein: 719-790
Range on HMM: 11-79/85.0
VDSRNLTLEWPRP---DGHVDFYTLKWWPTDEEDrvefknVTQLEDLSSPSVRIPIEDLSPGRQYRFEVQASSNG
| |..|||.| | .|... |........... ... ...... . ...| ||..|.|.||| ...
vtstsltlsWsppkdgggpitgYeveyrekggge......ewkeftvprtttsvtltgLkpgteYefrVqavnga
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 1487-1584 | 3.8e-11 | 36.9 | In-house | 224-343 (349) | alignment | ||
Range on Protein: 1487-1584
Range on HMM: 224-343/349.0
HFTTWPDFGVPEPPQSLVRFVRAFRDVIGT----------DMRPIIVHCSAGVGRSGTFIALDRILQ-------HIHKSDYV-----DIFGIVFAMRKER
. |.| .. |.|... . |.| . .. ...|||||| ||.|... || .|. . | .. |. || .|| |
qvknwldlslllnPisilqalevkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqr
VFMVQTEQQYVCIHQCLLAV
. ||| .|.. |...||
ismvqnlaqfiaiyealLky
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1306-1394 | 3.9e-11 | 36.9 | In-house | 3-88 (440) | alignment | ||
Range on Protein: 1306-1394
Range on HMM: 3-88/440.0
NRPVHVKDFSEHYRimSADSDFRFSEEFEeLKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNS
.||. | ||... . . | .|. | | | . |.|| |. |||. ||| ||||| |. | |||||| |. | .|
qrpiivadfadyvq..nnrrsrafedews.llpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingies
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 1520-1584 | 5.9e-11 | 36.8 | In-house | 230-294 (297) | alignment | ||
Range on Protein: 1520-1584
Range on HMM: 230-294/297.0
PIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAV
...||||||||||| . | ||. . | |. |. .|..| .||| .|. ... |.
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
fn3 | Fibronectin type III domain | 445-519 | 8.2e-11 | 35.1 | Pfam-A | 10-79 (85) | alignment | ||
Range on Protein: 445-519
Range on HMM: 10-79/85.0
DDRSNALHISWEPAE--TGRQDSYRISYHEQTNASevpapfpVAAESQITTNLTEYTLDSLLAGRRYLIAVQALSKG
. .|. |..||.| . | ..|.. | |... . . | ... . |..|| | .|..| . |||....
evtstsltlsWsppkdgggpitgYeveyrekggge.......ewkeftvprtttsvtltgLkpgteYefrVqavnga
|
|||||||||
fn3 | Fibronectin type III domain | 622-694 | 1.1e-10 | 34.6 | Pfam-A | 2-79 (85) | alignment | ||
Range on Protein: 622-694
Range on HMM: 2-79/85.0
PPQNLTLQTVHTNLVVLHWQAPE--GSDFSEYVVRYRTDASP--WQRISgLHEN--EARIKDMHYGERYLVQVNTVSFG
.|.||.. | .. ..|.|..|. |.... | |.||.. .. |.... . .. .. .... | .| ..| .|. .
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeft.vprtttsvtltgLkpgteYefrVqavnga
|
|||||||||
fn3 | Fibronectin type III domain | 547-607 | 1e-09 | 31.6 | Pfam-A | 15-80 (85) | alignment | ||
Range on Protein: 547-607
Range on HMM: 15-80/85.0
GLMLSWRSD--VNSRQDRYEVHYQRNGTRE---ERTMATNETSLTIHYLHPGSGYEVKVHAISHGV
|.||| .. ..|||.|. |. | |.| ..||.|.. | ||. ||..|.|.. .
sltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltgLkpgteYefrVqavngag
|
|||||||||
fn3 | Fibronectin type III domain | 152-230 | 1.1e-09 | 31.5 | Pfam-A | 1-80 (85) | alignment | ||
Range on Protein: 152-230
Range on HMM: 1-80/85.0
DPPANLSVQLRSSKSAFITWRPP--GSGRYSGFRIRVLGLTDLPFERSYSLEGNETlQLSAKELTPGGSYQVQAYSVYQGK
..| |||| ..| |. ..| || |.| ..|..... .. ..........| .. ..|.|| .|... ..| ..
saPenlsvsevtstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprttt.svtltgLkpgteYefrVqavngag
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 1363-1495 | 1.8e-08 | 28.7 | In-house | 3-125 (130) | alignment | ||
Range on Protein: 1363-1495
Range on HMM: 3-125/130.0
LPYDHSRFKlqpvddddGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCfekgrEKCDQYWPVDRVAM-FYGDIKVQLIID
|... || . | .||||... . .|.. || || | .||.| | .|.| |. |.||| . || | |
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsv.....eeedeywpdsePlewyeediivtltdr
THYHDWSISEFMVSRNCES--RIMRHFHFTTWPDFG
.. |.. .... . . |. . || |
defknikasnleiesdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1329-1392 | 3e-08 | 27.6 | In-house | 15-77 (244) | alignment | ||
Range on Protein: 1329-1392
Range on HMM: 15-77/244.0
FSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPvDDDDGSDYINANYMPGH
||| | |. . | | .| |||. ||||.|..| | .|||||||||. |
akeefvglsdhtreflqtnavlsanatknryinilpfdetrvilss.skkegsdyinanyiqgs
|
|||||||||
PTEN_1 | 1490-1537 | 4.9e-08 | 28.0 | In-house | 101-149 (196) | alignment | |||
Range on Protein: 1490-1537
Range on HMM: 101-149/196.0
TWPDFGVPePPQSLVRFVRAFRDVIGTDM--RPIIVHCSAGVGRSGTFIA
..|.|.| . ..| .... | . . | . ..||| ||.||||| .|
pieDhgap.slselfdicksfiewllsdpngnvVlVHCkaGlgRsGtvva
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 1485-1538 | 7e-08 | 27.8 | In-house | 81-135 (194) | alignment | ||
Range on Protein: 1485-1538
Range on HMM: 81-135/194.0
HFHFTTWPDFGVPEPPQSLVRFVRAFRDVIGTD-MRPIIVHCSAGVGRSGTFIAL
... .||.|.. . . | ||... ... | . ||| ||.||.||..|
eylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 1351-1425 | 9.3e-08 | 26.0 | In-house | 35-114 (347) | alignment | ||
Range on Protein: 1351-1425
Range on HMM: 35-114/347.0
PCNRPKNRFTNILPYDHSRFKLQPVD-----DDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIV
. ||| . | .| | | . || |||| .. |. .|.|.|| || .| .||.| . .|
ekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvv
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 1353-1438 | 1.1e-07 | 25.7 | In-house | 34-118 (332) | alignment | ||
Range on Protein: 1353-1438
Range on HMM: 34-118/332.0
NRPKNRFTNILPYDHSRFKLQPVDDDDgsDYINANYMPGHNSPREFIVTQGPLHSTR-EEFWRMCWESNSRAIVMLTRCFEKGREKC
| || . .|||| .| | | | |. ||... |.. .|..| |. |||| | . |... || . |.
nmdmnriphlycfdhsrvelapqdgkd..dfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 1486-1581 | 1.4e-07 | 26.1 | In-house | 85-172 (182) | alignment | ||
Range on Protein: 1486-1581
Range on HMM: 85-172/182.0
FHFTTWPDFGVPePPQSLVRFVRAFRDVIGTDmrPIIVHCSAGVGRSGTFIALDRILQHIHKSDyvdifGIVFAMRKERVFMVQTEQQYVCIHQCL
.. .|.|.||. . .... |. .. . . ||| || || | || . .. ... . .|..| .|| .| ....
vynfgwkDygva.sleriLdivkvvafalqeg..kvavhChaGlGrtGvliacylvyakrltae.....kaiklvrskrpksiqtreqvelvkefa
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 1396-1456 | 6.3e-07 | 23.1 | In-house | 236-293 (440) | alignment | ||
Range on Protein: 1396-1456
Range on HMM: 236-293/440.0
REFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKgreKCDQYWPVDRVAMFYGDIKV
|| || || || .|||. . . .|.|| . .| | ||||. .. .| . |
nafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftv
|
|||||||||
fn3 | Fibronectin type III domain | 821-886 | 7.9e-07 | 22.3 | Pfam-A | 12-79 (85) | alignment | ||
Range on Protein: 821-886
Range on HMM: 12-79/85.0
QDETITLSYTPT---PADSTRFDIYRFSMGDPTiKDKEKLANDTERKLSFSGLTPGKLYNVTVWTVSGG
.. ..||| .| .. |.... ..|.. ..||. . |.. . ..||.||. |...| .|.|.
tstsltlsWsppkdgggpitgYeveyrekggge.ewkeftvprtttsvtltgLkpgteYefrVqavnga
|
|||||||||
fn3 | Fibronectin type III domain | 343-419 | 1.9e-06 | 21.1 | Pfam-A | 3-78 (85) | alignment | ||
Range on Protein: 343-419
Range on HMM: 3-78/85.0
VLNVTFDEAytTSSSFRVRWEPPR-TYSEFDAYQVMLSTSRRIF-NVPRAANGDSVYFDYPDiLEPGRTYEVVVKTIAD
. |....| ||.|....|.||. .... |.| ..... . . . ... . .. |.||..||. |... .
Penlsvsev..tstsltlsWsppkdgggpitgYeveyrekgggeewkeftvprtttsvtltg.LkpgteYefrVqavng
|
|||||||||
DUF1049 | Protein of unknown function (DUF1049) | 1253-1298 | 2.4e-06 | 14.5 | Pfam-A | 22-67 (68) | alignment | ||
Range on Protein: 1253-1298
Range on HMM: 22-67/68.0
TVIVAATVSAVLLVAMVLVVVYCQHRCQLIRRASKLARMQDELAAL
.....| . .||.....|... ..| || | ..|.... ||..|
lllliafllGallglLlsvlfllklrrqlrrlqkqlkklekeldql
|
|||||||||
Big_5 | Bacterial Ig-like domain | 328-422 | 6.4e-06 | 14.8 | Pfam-A | 9-92 (107) | alignment | ||
Range on Protein: 328-422
Range on HMM: 9-92/107.0
SSVPTTARYLTVPERVLNVTFDEAYTTSSS-FRVRW-EpprtyseFDAYQVMLSTSrrifnvprAANGDSVYFDYPDILEPGRTYEVVV-KTIADNV-N
|..|.. .. . .||.|. ...| . |. .| ...| ..|..|... . |....||.|.| ... |. |
stsPadgatnvavnaeititFsepvdaasvtaaivial.......sdsatvavtgs........svagktvtitptaaLaanttYtvtvtagvkDlagn
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 1397-1495 | 7.2e-06 | 19.8 | In-house | 138-234 (244) | alignment | ||
Range on Protein: 1397-1495
Range on HMM: 138-234/244.0
EFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCfekgrEKCDQYWPVDRVAMFY-GDIKVQLIIDTHYHDWSISEFMVSR--NCESRIMRHFHFTTWPD
|.|.|| || | .||.| | .|.| |. |.||| .| || | | ... |.. . | . . | . ||
eyiltqhpladtsmdfwkmmlerhvnvlvvlgsv.....eeedeywpdseplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwps
FG
|
dg
|