Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 1-316 | 7.5e-165 | 542.6 | In-house | 2-318 (318) | alignment | ||
Range on Protein: 1-316
Range on HMM: 2-318/318.0
IPVDEFEEHVRRLHANGELLFSQEYGAF-RSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPET
|.|...|.|||||...||||.|.|| .. ||..||||..||...|..||||.||.|.||.||.||..||...||||||||.||||....|||||.|||||
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
CHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV
..|||||||||||.||||.|..||||..|.|.||||.||..|| ..|.....||||||..|.| |.|... |.|.| |||||.|||.|||.|..|.|..|
ieDfWrmvWeqnsavivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlv
RKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMR
|..|........||.||||||||||||.....|..|.||.|||.|||...|..|| |||||||.||||..|.||||||.|.||||..|.|||.||.||..
rqvskaqqksgagpivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtevdasdlrsrirelre
PSTDTGQTEMDAEFQRL
.....|.||||||||||
qdpesgttemdaefqrl
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 1-328 | 5.2e-157 | 518.9 | In-house | 5-332 (564) | alignment | ||
Range on Protein: 1-328
Range on HMM: 5-332/564.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
|||.|..|||..|.||..| |..|| .......| ... ..||. ||||.||.|.||.|| |...|||. ||||||...|||||...|||.||||.||.
ipvaelkehvaklkansdlkfeeeykkieegqqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaeti
HDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVR
.|||||||||||..|||.|..||.|. |||.|||..|...|| ..|......||.||.||.| .|.. | | |.| |.|.|.|||||||.| ||.|...|
edFWRmvweqnsstiVmltkleEkgkvkchkYWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlir
KSSAVNlTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRP
|..|.| ..| ||.|||||||||||||..|||| |.||..|.|||.|.||..|| ||| ||| |.||. ||...|||.|||.||.....|.|....|..
kvraln.epdagPivVhCSaGVGRTGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgntevesenlkqhlqkLaev
STDTGQTEMDAEFQRLS-RNKAPPSKFQS
..||..|....|||||. .. ....|..
eedtemtgleleFqrLatakeieleefav
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 304-575 | 4.4e-147 | 484.2 | In-house | 17-287 (318) | alignment | ||
Range on Protein: 304-575
Range on HMM: 17-287/318.0
TGQTEMDAEFQRLSRNKAPPSKFQSaNLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCC
.|......|..||||... .....| . ||||.||||||.|.||.|||.|.|....||||||||||||||..|||.||.|||.|.||.|||||.|||...
sGelllseeyerlsrseetvtslks.lepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsa
TIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQL
.||||.||.|.||.|||||||.|...|.|.||||. ......||..||||||.|.|..||.||||..|.||| |.|.||..|.||..||...|||.|...
vivmltqeeergkakvhryWPskgsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvskaqqksgagp
TAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPYN
..|||||||||||||.||.||.||.||||.||||||||||||||..||||..||||.|..| |.|.|.|..
ivvhCsaGvGrtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 322-572 | 2.2e-122 | 404.6 | In-house | 36-285 (564) | alignment | ||
Range on Protein: 322-572
Range on HMM: 36-285/564.0
PPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHR
. .....|| |.||.||||||...|| .||.|.. .||||||||..||||...||.||||.|...|| |||||.|||...|||||.. |.||||.|.
qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkvkchk
YWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQqKCGVQLTAVHCSAGVGRTGVFCAV
||| |.....|.|.|.. . ... ||..|.||....|.| || |||..||.||| | |.|. .|.||| .|.... ... . . |||||||||||.|...
YWPekgtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvraln.epdagPivVhCSaGVGRTGtfivi
SILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFD
....||.|.|..||..|.||.||.||.|||||.||| |..... |.|....
damlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgn
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 1-314 | 4.1e-118 | 389.1 | In-house | 5-319 (319) | alignment | ||
Range on Protein: 1-314
Range on HMM: 5-319/319.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
|.|.|..|....|...|| |. .|. .. ....| ... .. |. ||||.|| |.|..|| |....| . ||||||...|||......||.|.|| .|
ievqeLkerlkalastgetllekefkllkeavndtfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlenti
HDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKR-SGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV
.||||||||..| ..||.|. |....|...|||. ..|| . |.. . ||.|| || . ... |. | |.| ...||.||||.||.. ||.|...
edfWrmvWeeessivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldll
RKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMR
.. .. ||.|||||||||||||..|.|| | |.. |...||...| .|| |||.||| ..|| .|...||||. .|||||. .|||.|.|.|
krirksrektqsgPivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdteievqdlrdrlkqlae
PSTDTGQTEMDAEFQ
.|||.| .. |||
kvadtgetglerefq
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 1-292 | 2.1e-113 | 374.5 | In-house | 1-301 (563) | alignment | ||
Range on Protein: 1-292
Range on HMM: 1-301/563.0
IPVDEFEEHVRRLHANGELLFSQEYGA---FRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTS-DYINANYLDGYRKQREYIAAQGPL
.||.||..|| |||.|. ||.|. | ..... .|| .. |. |||| ||.|.|. || |.|. | . |||||||.|||.|....||.||||
vpvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgpl
PETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKR-----SG-SPEERMVLQYHYTAWPDHGVPN
..|..|||||.||||. .|||.|| .|||| ||..|||. .|..||...|..... |. ||.|.. .| .|..| ||||| |||||||.
kdtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPe
SVTSVLNFVRKSSAVNLtEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDL
. . ||.||.|||| | .. ||.||||||||||||||.|.|. ||.||.| .|.|.. . ..| ||| .|| |.||. .||.|||||| ..||..| ..
hslpvLifvkkssaank.aeaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellaeqv
RQ
..
ee
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 2-279 | 3.8e-105 | 346.1 | In-house | 8-286 (293) | alignment | ||
Range on Protein: 2-279
Range on HMM: 8-286/293.0
PVDEFEEHVRRLHANGELLFSQEYGAFRSPDT-VTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
...|||||....|. .| ||.|| ... .. . . . ...|| ||||.|| ..|| || |........||||||||..||. .||.||.|||||||
klekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetv
HDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSS-GSQNYGVIHVNMMSTVELSDYTIRSFGVKRsgSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV
.||||||||..|..|||.|.. |.|..||..|||. ...|| |.|..... ||.|..||.. ... . ||| | |||.|.|||||||.. ...|.||
ddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektktlldfv
RKSS-AVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIA
|. |.. |.. .|.|||||||||||||.. .| |..|. | .||.. |. || .|||.|| |.||. ||...|. .
rtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 276-574 | 2.2e-103 | 341.1 | In-house | 10-305 (308) | alignment | ||
Range on Protein: 276-574
Range on HMM: 10-305/308.0
EAIACGDTEIQARDLRQRIKELMR-PSTDTGQTEMDAEFQRLSRNKApPSKFQSANLPVNKHKNRYANVLPYDDTRVRLtmqavTEGSDYINANYIDGY-
|.....||.|.. .|......|.. .. . ...||..| ..| . .. .|.|| ||.|||| ..|||| .||.| ||||||||.|.|||
elllfrdtsilvsslklsvldllkllekaldlglleeefeellsvkp.lleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgys
-MSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGK---QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQ
....|||||.| |.|. |||||.|||.. .|||| ...| |..| ..||| . ... .|...|..|. ...|||..|....||.... ||.|....
sklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfh
FTAWPDIGSPDSGGGLIDLIGQVQRWQQKcgvQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
.|.||| | |.| |.|.. .|...... ..|||||||||||.|.|. .|.|.|..| .||||..||.|||||| ||||.|||.|.|..| |||.
ytnWpdhgvPpspeilldflelvrkslpg...gpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylk
SFDPY
.. .
lkltk
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 1-278 | 4.6e-103 | 339.9 | In-house | 5-286 (288) | alignment | ||
Range on Protein: 1-278
Range on HMM: 5-286/288.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRSPD-TVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPET
|.|.|....|..|.||| .. .|. ...| ..| ...| ..|. |||| .| ..||.|| |....|...||||||.|.|||...|..||.|||||.|
isveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpnt
CHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRS----GSPEERMVLQYHYTAWPDHGVPNSVTSV
..||||||||||.|||||.|...|.||.||.||||..||..|| |.|...|...|.|||.| . |.. |. |.|.| ..|||.|||||||.|....
vedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspell
LNFVRKSSAVNLtEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
|.|.|. .. . ||.|||||||||||||....| | ....| .|||...| .|| ||. ||| ..||......|||..
ldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 281-568 | 7.4e-102 | 335.9 | In-house | 1-286 (288) | alignment | ||
Range on Protein: 281-568
Range on HMM: 1-286/288.0
GDTEIQARDLRQRIKELMrpstDTGQTEMDAEFQRLSRNKAPpSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFI
|||||....|......|. .|.| . .||..| ..... .. .|.|| |..|||| ..||||..||.|.. ||||||||.||||| .|..||
gdteisveellklvlkll....angltglleefeellsllpd.ltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfI
ATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNT----KESASRVVRQYQFTAWPDI
|||.| |.|. |||||.|||.. .|||| ...| |..| ..||| .... .|...|..|. ...|||..|...|||. ... || |.....|.|||
atqgPlpntvedFWrmvweqnvrvIvmltklvelgrekcaqYwplggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdh
GSPDSGGGLIDLIGQVQRWQQkCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
| ||| |.|.. .|..... | ..|||||||||||.|.|. .|.|.|..| .|||...||.|||||| |||| |||.|.|..| |||
gvpdspellldflrlvrkala.sgggpvvVHCsaGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 1-313 | 1.3e-100 | 331.5 | In-house | 14-330 (330) | alignment | ||
Range on Protein: 1-313
Range on HMM: 14-330/330.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRS-PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPET
.||...|| .|. |. || .|. |. . | | . .. |. |||. || .|. || |...|| ..|||||| ..|||... ..||||||. ||
lpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeet
CHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGS----PEERMVLQYHYTAWPDHGVPNSVTSV
.|||||.|||.| |||.|. .|| . ||.||||. |. || |.|.. ...| |||.| | |.. . ..|.| |.|.|.||| ||| .
vedfwrmiweqksativmltelkerkeekcaqywPdeGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGm
LNFVRKSSAVNLTEDYgPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIK
|....| ..| . |.|||||||||||||..|.|| |.|..|| |||.. | || || ||| . ||..|. |||| ||||... | ....
lkllkkvkklnqqsag.pivvhcsaGvGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdteldvsslekhlq
ELMRPSTDTGQTEMDAEF
.| |.| .. .. ||
klynkitgtdkigleeef
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 281-574 | 1.3e-100 | 331.5 | In-house | 1-296 (298) | alignment | ||
Range on Protein: 281-574
Range on HMM: 1-296/298.0
GDTEIQARDLRQRIKELMRPSTDTGQTEMDAEFQRLSRNKA--PPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKA
|.|||.|.||.. ...| . ... | ...|||||.. . . . . |. | ||.|||||.....| .||.|. . | |||||| ....| ..|
gnteieaedlkaalqklaavkkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrna
FIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGS
|||||||.. |. |||||..|.| ||||| . |..|.|.|.||| .. . |.. |..|....| |.|.|..||...||. .| ||| .|| ||| |
fiatqaPltetvedFWrmvteedigtiVmltnleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgv
PDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPY
| ..||. .|...||..| . |.|||||||.| |.|.. ..||.|.| .|||||.|| ||..||..|||.||| |.|. |.|.||. .
penatsvldllrkvrasqqqagnkpvivqCsaGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnde
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 5-316 | 2e-100 | 331.4 | In-house | 4-314 (317) | alignment | ||
Range on Protein: 5-316
Range on HMM: 4-314/317.0
EFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFW
...... .|.... ....|. ..| . | ... ..|. |||| .| .||.|| |.|..||. ||||||.| ||....|..||.|||||.|..|||
dlllalldllksdftalleefedllslkldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFw
RMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSA
||||||...||||.|..||.||.||.||||. ....|| ..|...|..||...|.| . |. .|..|.|.| ..|||.||||||| | ...|.|... .
rmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavre
VNLtEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRPSTDT
.. .. ||..||||||||||||..... | ... | .|||.. | .|| ||. .|| ..||. ..|.||| . ...| . | .| ....| .| . .
ale.dpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltlepaselklkllklliplald
GQTEMDAEFQRL
. .... |...|
dvklkekelkll
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 3-281 | 1.8e-99 | 328.2 | In-house | 28-302 (308) | alignment | ||
Range on Protein: 3-281
Range on HMM: 28-302/308.0
VDEFEEHVRRlhANGELLFSQEYGAFRSPD-TVTSHHSLNQANRFKNRYNNITAFDHCRVLLqpiegDPTSDYINANYLDGY--RKQREYIAAQGPLPET
|... ... . |.. |...|. ...| . ..| ..|. |||| .| ..||.|| | |..||||||.| ||| ...|..||.|||||.|
vldllkllek..aldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpnt
CHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSS---GSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVL
..||||||||||.|||||.|...|.||.||.||||.. ||..|| ..|...|. .|.|||.| . .. .|..|.|.| ..|||.|||||||.|....|
vedFwrmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeill
NFVRKSSAVNlteDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACG
.|... .. . ||.|||||||||||||....| | ....| .|||...| .|| ||. ||| ..||......||| . .
dflelvrksl...pggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylklk
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 304-572 | 2.6e-99 | 327.3 | In-house | 20-287 (319) | alignment | ||
Range on Protein: 304-572
Range on HMM: 20-287/319.0
TGQTEMDAEFQRLSRNKAPpsKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCC
||.| .. ||. |. .. .|.||. . ||.|||| |.|.|| ||| |. .||||||||..|||| ...|||||||. .|| |||||.||...
tgetllekefkllkeavnd..tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeess
TIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESA-SRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQ
..|||.. | .|||...||| ..... |.|.|....... .|||.|..|. . .. .| | ..|.|.||| . |... .|.||...... ..| .
ivvmltklveklkvklkkywpeenfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrektqsg
LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFD
||||||||||| |..... .||.| |...|||.||..|| ||. |||..|||.|.|..| |.....|
PivvhCsaGvGRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagd
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 5-314 | 3.5e-99 | 326.6 | In-house | 8-313 (314) | alignment | ||
Range on Protein: 5-314
Range on HMM: 8-313/314.0
EFEEHVRRLHANGELLFSQEYGAFRSPdtvtSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFW
. ... |... | .|| .. . .. || |||...| |.|..|| |..|.||| ||||||...|.|.. ...|..||||.|| .|||
dllqsiallkraegygfkeeyeslfeg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfW
RMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQnYGVIHVNMMSTVELSDYTIRSFGVKR--SGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKS
|.|...|. |||.|. | ||.|| .||| ... || |.|....| |... .| | |.. | | |.| |.....||||.||.| |..|..||.
rlvydencasivmltelvevgrvkClkyWPedtev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrv
SAVNLTeDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRPST
. . . |..||||||| |||||...|| | |. | .|||.| | || .. ||..|.||..|.||.||| ||.| | . ... .| .| .
kksqee.eaGrivvhCsaGaGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvileaclcgetaipvsefkalylesirldp
DTGQTEMDAEFQ
.| ... |||
qtnssqlkeefq
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 24-286 | 9.2e-98 | 322.2 | In-house | 32-298 (298) | alignment | ||
Range on Protein: 24-286
Range on HMM: 32-298/298.0
EYGAFRSPDT----VTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVT
|. ..| ... . ...|. |||| .| |.|..||.|. ...| |||||| .|..|... .||.|.||.|| .||||||.|... .|||.|
efqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmlt
NCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCS
| || ...|.|.|||..|...|| |.|...|. | .|...| . |... . .||.| | |.| |||.|||. ||||...|| | . |..|.||
nleeldktkyhkywPdegketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvrasqqqagnkpvivqCs
AGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQ
|||||.||...||. | |...| .|||...| .|| .| .|| |.||| |... |||......||.
aGvgRsGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfndeie
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 309-573 | 1.7e-97 | 321.5 | In-house | 2-279 (284) | alignment | ||
Range on Protein: 309-573
Range on HMM: 2-279/284.0
MDAEFQRLSRNKAPPS-KFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVT-EGSDYINANYIDGY-----MSKKAFIATQAPIPDTIPDFWRMIWEQD
...||..| ... ... .. |.|| |..|||| ..||||..||.|.. . |.||||||.|.||| ..||.|||||.| |.|. |||||.|||.
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
CCTIVMLSQEMESGKVKVHRYWPGKQ-PTSIGNLVVEMLHDKQFDDYIMREFKVTNTK-ESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQK-
. .|||| ...| |..| ..||| .. . .|.. |..|. ...|||..|....||.. .. || |.....|.||| | |.| |.... .|......
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
CGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEA---MVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDP
| ..|||||||||||.|.|. .|.|.|..| .|||...||.|||||| |||| |||.|.|..| ||| ..
pgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 31-283 | 6.1e-96 | 316.4 | In-house | 15-279 (284) | alignment | ||
Range on Protein: 31-283
Range on HMM: 15-279/284.0
PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGD-PTSDYINANYLDGY-----RKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEER
. ... ...| ..|. |||| .| ..||.|| |....|| ..||||||.|.||| ......||.|||||.|..||||||||||.|||||.|...|.
klllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelven
GRIKCHQYWPSSG-SQNYGVIHVNMMSTVELSDYTIRSFGVKRSG-SPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLT-EDYGPMVVHCSAG
||.||.||||..| ...|| ..|...|. . .|||.| . ... | . |.|.| ..|||.||||||| |....|.|.|. .. .. ||.|||||||
grekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaG
VGRTGTYVVIDAQLKRIQAEA---TVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDT
||||||....| |.....| .|||...| .|| ||. ||| ..||......|||.. .. |
vgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylklklt
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 304-568 | 3.7e-95 | 313.8 | In-house | 9-272 (273) | alignment | ||
Range on Protein: 304-568
Range on HMM: 9-272/273.0
TGQTEMDAEFQRLsRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLtmqaVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCC
.| | . .||..| .. |. ... |.|| ||.|||| ..||||..||.| .|||||||.|.||| .|..|||||.| |.|. |||||.|||..
lgltllleefell.lslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvr
TIVMLSQEMESGKVKVHRYWPGKQ---PTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKC-
.|||| ...| |..| ..||| .. .. |.. |..| ...|||..|....||.. . ||.|.....| ||| | |.| |...| .|.......
viVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealp
-GvQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
. ..|||||||||||.|.|. .|...|..| .|||...||.||.||| |||| |||.|.|..| |||
sn.gpvvVHCsaGvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 1-276 | 4.3e-95 | 313.6 | In-house | 2-275 (278) | alignment | ||
Range on Protein: 1-276
Range on HMM: 2-275/278.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
|.| ........|..|. |...|. ..| .. | ..| ..|. |||| .| ..||.|| |....||. ||||||.|.|||...|..||.|||||||.
isvkdllkallelllnlktllllefeellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetv
HDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPsSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVR
.||||||||.....|||.|...|.||.||.|||| .||..|| ..|..... .|.|||.| . |.. |..|.|.|..|||..||||||| |....|.|..
edFwrmvwelgvttivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflk
KSSAVNLtEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
. .. . ||..||||||||||||..... | ... | .||... | .|| || .|| ..||. ....|||
avreale.dsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealle
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 308-571 | 3e-94 | 311.1 | In-house | 19-279 (317) | alignment | ||
Range on Protein: 308-571
Range on HMM: 19-279/317.0
EMDAEFQRLSRNKAPpsKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVM
. ||..| ..| . .. |.||.||.|||| ..||||..||.|. ..||||||.|.||. |..|||||.| |.|. |||||.|||....|||
alleefedllslkld..tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivm
LSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQkCGVQLTAVH
| ...| |..| ..||| .... .|...|..| .. .....|...|.....| || |.....|.||| | |.| |.|.. .|..... . ..||
LteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale.dpggpvlVH
CSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSF
|||||||||.|.|. ...|.|. | |||...||.|||||| .||| |||.|.|. | ||| .
CsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrk
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 305-573 | 1.3e-93 | 308.8 | In-house | 11-282 (297) | alignment | ||
Range on Protein: 305-573
Range on HMM: 11-282/297.0
GQTEMDAEFQRLSRNKApPSKFQSANLPVNKHKNRYANVLPYDDTRVRLtmqaVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCT
. . . ||..| .... . .. |.|| |..|||| ..||||.|||.| ||||||||.|.||| |..|||||.| |.|. |||||.|||.. .
flalllkefeellplll.lgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtv
IVMLSQEMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQ--FDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKC-
||||....| |..| ..||| . .. |...|..|. .. .|||..|...||.|... ||.|.....| ||| | |.| |.|.| .|......
Ivmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllp
GVQLTAVHCSAGVGRTGVFCAVSILIERLK---AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDP
. . |||||||||.|.|.|. .....|. | ||....||.|||||| .||| |||.|.|..| |.| ....
sggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkklt
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 33-289 | 3.3e-93 | 307.5 | In-house | 28-288 (297) | alignment | ||
Range on Protein: 33-289
Range on HMM: 28-288/297.0
TVTSHHSLNQANRFKNRYNNITAFDHCRVLLqpieGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQY
. ..|...|. |||| .| ..||.|| | .|. ||||||.|.|||. .|..||.|||||.|..||||||||||..||||.|...|.||.||.||
lgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgrekcaqy
WPSS--GSQNYGVIHVNMMSTVE--LSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTE-DYGPMVVHCSAGVGRTGT
||. .|..|| ..|...|. . |.|||.| . |. |..|.|.| ..||| |||||||.|..|.|.|... |. . ||..|||||||||.||
wpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCsaGvgRsgt
YVVIDAQLKRIQ---AEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARD
....| | ... | .||....| .|| ||. .|| ..||. ....||| . ...| .....
fiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkkltkepllk
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 28-278 | 1.5e-92 | 305.2 | In-house | 21-272 (273) | alignment | ||
Range on Protein: 28-278
Range on HMM: 21-272/273.0
FRS-PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLqpieGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGR
..| .. .| ..| ..|. |||| .| ..||.|| | ||..||||||.|.|||...|..||.|||||.|..||||||||||.|||||.|...|.||
llslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgr
IKCHQYWPSSG---SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTE-DYGPMVVHCSAGV
.||.||||..| |..|| ..|...|. . .|||.| . ....|..|.|.| ..||| ||||||| |..|.|.|... .. . . ||.||||||||
ekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGv
GRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
|||||....| | ....| .|||...| .|| || ||| ..||......||| .
gRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealleyl
|
|||||||||
DSPc_SM00195 | 309-568 | 2.1e-92 | 304.6 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 309-568
Range on HMM: 2-262/263.0
MDAEFQRLSRNKAPPsKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVML
...||..| ... | ....|. . ||.|||| |.||||.|||.|. . .|||||||||||.|. .||..||||.| |.|. |||||.||... .||||
lkeefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
SQEMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQFD-DYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgVQLTA
..|.|.|| |..|||| . ... .|.. |.. . .. . ..|.|....|..... .| |.|||...||| | ||| ...|. .|. .... . .
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
|||||||||||.|....|....|..| .||.|..||.||.||| ||||.||| |.|... ||.
VhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 309-568 | 2.1e-92 | 304.6 | In-house | 2-262 (263) | alignment | |||
Range on Protein: 309-568
Range on HMM: 2-262/263.0
MDAEFQRLSRNKAPPsKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVML
...||..| ... | ....|. . ||.|||| |.||||.|||.|. . .|||||||||||.|. .||..||||.| |.|. |||||.||... .||||
lkeefekleestspk.etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivml
SQEMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQFD-DYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgVQLTA
..|.|.|| |..|||| . ... .|.. |.. . .. . ..|.|....|..... .| |.|||...||| | ||| ...|. .|. .... . .
teeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpiv
VHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
|||||||||||.|....|....|..| .||.|..||.||.||| ||||.||| |.|... ||.
VhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 304-568 | 2.5e-92 | 304.6 | In-house | 17-277 (278) | alignment | ||
Range on Protein: 304-568
Range on HMM: 17-277/278.0
TGQTEMDAEFQRLSRNKAppSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCC
...| . .||..| ..| . |.|| ||.|||| ..|||| .||.|.. ..||||||.|.||| ...|||||.| |.|. |||||.||...
nlktllllefeellsfkl..dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvt
TIVMLSQEMESGKVKVHRYWPgKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQkCGVQL
||||| ...| |.|| ..||| .... .|...|..| ...|||..| ..|||.... || |..|....||| | |.| |.|.. .|.....
tivmLtelvelgrvkcaqYwp.ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale.dsngp
TAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
..|||||||||||.|.|. .|.|.|. | ||....||.|||||| .||| .||.|.|. | |||
vlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 325-568 | 7.1e-92 | 302.8 | In-house | 49-295 (330) | alignment | ||
Range on Protein: 325-568
Range on HMM: 49-295/330.0
KFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWP
.. |. ||.|||. |.|||| .|| |... .| |||||| .|||| |. |||.| | .|. |||||||||. .|||||.. | . | ..|||
tlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelkerkeekcaqywP
GKQPTSIGNLVVEMLHDKQFDDYIMREFKVT----NTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVqLTAVHCSAGVGRTGVFCA
. . ||. ||. ... || .|.| |. .|.| .||.|||. ||.|||.| | . |...|. .|.. .|. . ||||||||||| |..
deGlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag.pivvhcsaGvGrtGtfiv
VSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
.. ..||.||| .||||..||.|| ||| ||||.|||||.|..| ||
ldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyy
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 285-569 | 1.2e-91 | 301.8 | In-house | 7-286 (293) | alignment | ||
Range on Protein: 285-569
Range on HMM: 7-286/293.0
IQARDLRQRIKELMRPStdtgQTEMDAEFQRLSRNKAPpSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQA
|..... . .|.. . | .... |...|. . . ..|.|.||. |||| |.|||| .||.|. . ..||||||||||.|| |.. |||||
iklekfeehvkkmkads....dlrfseeyeelkavgkd.qavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqG
PIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGK-QPTSIGNLVVEMLHDKQFDDYIMREFKVTNtkESASRVVRQYQFTAWPDIGSPDSGG
|.|.|. |||||.||. . .|||| | .| |||| ..||| . .|. |.. |....... .|...||.|... |...| ||||.||.||| | |..
PlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiek..ekeerkvrqyhftsWpdhgvPektk
GLIDLIGQVQRWQ-QKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
|.|.. .|.... ... . . |||||||||||.| |. |..... | .||.| .| .|||.| .|||..|| | .|.. ..|.
tlldfvrtvreaiektaskrPivvhCsaGvGRtGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllr
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 1-297 | 2e-91 | 301.3 | In-house | 4-305 (307) | alignment | ||
Range on Protein: 1-297
Range on HMM: 4-305/307.0
IPVDEFEEHVRRLHANGELLFSQEYGAFR-SPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPET
|..|. || .. . . . .. .|| . ... | .. | .||||..|.|||. || |..|.|. .||||||... ||......||||.|. .|
iaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveat
CHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG-----SPEERMVLQYHYTAWPDHGVPNSVTS
.|||||..||.. .|||..| .| | ||..||| ..|| | |...|. . |||.||.. | . . ...| |.|||||.|.| ||.. ..
igDfWRmiaeqevtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevarg
VLNFVRKSSAVNLTEdYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRI
.|..... .. .. .|.||||||||||.|..| .| |....|| .||... | || ||||.|| .||| .. ||. . |||... .|| ..|
llklieqvrelykln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdtdedvddledai
KEL
..|
erl
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 2-297 | 2.8e-91 | 300.9 | In-house | 5-302 (305) | alignment | ||
Range on Protein: 2-297
Range on HMM: 5-302/305.0
PVDEFEEHVRRLHANGELLFSQEYGAFRSPDTvTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCH
.|....... ... . . ..| .. . .. . . ..||. |||...|| .|. |. |.. | .. ||||||.|.|||... .||.|||||..| .
alddlaayikearvysdkgleaqykslyeeee.sidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntva
DFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQ--NYGVIHVNMMSTVELSDYTIRSFGVKR-SGSPEERMVLQYHYTAWPDHGVPNSVTSVLNF
||||...| ..|||.|. | |. ||.|||| | .. ..| ..|.. |. . |||..| . . ... |.| ||||. | |||||||.. ||.|..
dfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllsl
VRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKEL
... . |..|||||||||||.....| .| |...| .|||.... || .| ||| |||| .||.| | | ||||.| .|| |.. |
ikrvqkdqkkdkgvpllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiigsnlrarvnkl
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 41-280 | 3.7e-91 | 299.8 | In-house | 6-244 (250) | alignment | ||
Range on Protein: 41-280
Range on HMM: 6-244/250.0
NQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIkCHQYWPSSGSQN
. .|. |||| .| |.|..||.|.. .|| |||||| .|.||.... .||.||||..| ||||||.|..| .|||.|| .| .. .||||| ....
kpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPvekaek
YGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQA
|| ..|...|. | .|||.| . . . .||.| |.|...||| |||. |.||....| | . . .|..|.|||||||.|....||| |.|..
yGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerlkk
EATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIAC
| .|||.... .|| .| .|. ..||| .. ..|.|. .
ekvvdvfkvikvlrkdrphavesleqyvfvyeiilkalds
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 2-282 | 1.1e-90 | 299.4 | In-house | 15-293 (297) | alignment | ||
Range on Protein: 2-282
Range on HMM: 15-293/297.0
PVDEFEEHVRRLHANGELLFSQEYGAFRSPDTvTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEG-DPTSDYINANYLDGYRK-QREYIAAQGPLPET
|.. .. ......||. |. .|. | ..| ..|. |||| .| ..||.|| |.|..| |. ||||||.|.|||.. .|..||.|||||||
plsvldlllllekansktllllefeellslkp.dysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpet
CHDFWRMVWEQNSRVIVMVTNCEERGRiKCHQYWPSSGSqNYGVIHVNMMSTVELSDYTIRSFGVKRsgSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV
..|||||||||...||||.|...|.|| ||.||||..|. .|| ..|..... .|..||.| . |.. . |.|.| ...|| |||||||.|....|.|.
vedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtn..ngesrtvthfqytgwpdhgvppslelllefl
RKSSAVNLTE-DYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGD
.. .. . . ||..||||||||||||..... | ... | .|||.. | .|| ||. .|| ..||. ..|.||| . ...
elvrealaelpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrkl
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 305-571 | 1.8e-90 | 298.7 | In-house | 30-292 (297) | alignment | ||
Range on Protein: 305-571
Range on HMM: 30-292/297.0
GQTEMDAEFQRLSRNKAPpskFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVT-EGSDYINANYIDGYMS-KKAFIATQAPIPDTIPDFWRMIWEQDC
. | ...||..| ..| . . |.||.||.|||| ..||||..||.|.. . ..||||||.|.||| ...|||||.| |.|. |||||.|||..
sktllllefeellslkpd...ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgv
CTIVMLSQEMESGKvKVHRYWPGKQPtSIGNLVVEMLHDKQFDDYIMREFKVTNTKESasRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKC-GV
.|||| ...| |. | ..||| .. |...|..| .. |.|..|...|||..|| | |...|.| ||| | |.| |.... .|....... .
tvivmLtklvelgr.kcaqywpeegg.tygdftvtllkvehldgytvrtlevtnnges..rtvthfqytgwpdhgvppslellleflelvrealaelpkg
QLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSF
..|||||||||||.|.| ...|.|. | |||...||.|||||| .||| .||.|.|. | |.| .
gpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkrk
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 3-278 | 2.5e-90 | 298.6 | In-house | 11-304 (307) | alignment | ||
Range on Protein: 3-278
Range on HMM: 11-304/307.0
VDEFEEHVRRLHANGELLFSQEYGAFRSPDTV---TSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGD-PTSDYINANYL--------DGYRKQREYI
. .. .|..|.... .. .|. ..| . . ..| ..|. |||| .| ..||.|| |....|. ..||||||.| |||...|..|
alkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfI
AAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQ-NYGVIHVNMMSTVELSDYTIRSFGVKRS-GSPEERMVLQYHYTAWPDHGV
|.|||||||..|||||.|||...||||.|...|.||.||.||||..|.. .|| ..|...|. .|..||.| . |... |. |.|.| ..|||.||||||
atqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgv
PNSVTSVLNFVRKSSAVNLTE-DYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEAT---VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
| |. ..|.|... ... . . ||..||||||||||||..... |.....| | ||... | .|| || .|| ..||. ....||| .
ppsfeelldfieevrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 303-568 | 5.4e-90 | 297.5 | In-house | 23-304 (307) | alignment | ||
Range on Protein: 303-568
Range on HMM: 23-304/307.0
DTGQTEMDAEFQRLSRNKAP-PSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVT-EGSDYINANYI--------DGYMSKKAFIATQAPIPDTIPD
.. | . .||..| . . . . .. .|.||.||.|||| ..||||.|||.|. . |.||||||.|. ||| .|..|||||.| |.|. |
ldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetved
FWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGK-QPTSIGNLVVEMLHDKQFDDYIMREFKVTNT-KESASRVVRQYQFTAWPDIGSPDSGGGLIDLIG
||||.|||.. .||||....| |..| ..||| . .. .||..|..| .. |.|..| ..||.. ... || |.....|.||| | |.| |.|.|
FwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfie
QVQRWQQKC-GVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAM---VDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
.|....... . ..|||||||||||.|.| .....|..| . ||....||.|||||| .||. |||.|.|. | |.|
evrkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallell
|
|||||||||
DSPc_SM00195 | 35-278 | 7.5e-90 | 296.2 | In-house | 17-262 (263) | alignment | |||
Range on Protein: 35-278
Range on HMM: 17-262/263.0
TSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWP
..... ..|. ||||.|| .|| || |...|....||||||||..|..|...|||.|||||.|..||||||||.....|||.|..||.|..||..|||
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
SS--GSQNYGVIHVNMMSTVELS-DYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEdYGPMVVHCSAGVGRTGTYVVI
.. |....| |.|..... . . ....| . .. | |.| | ||.|..|||||||.| .|||...|. . |. ||.|||||||||||||.|.|
eesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvti
DAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
| |.....| .||. . | .|| || ||| ..|| |....||.|
diilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 35-278 | 7.5e-90 | 296.2 | In-house | 17-262 (263) | alignment | |||
Range on Protein: 35-278
Range on HMM: 17-262/263.0
TSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWP
..... ..|. ||||.|| .|| || |...|....||||||||..|..|...|||.|||||.|..||||||||.....|||.|..||.|..||..|||
etteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengkekcdrywp
SS--GSQNYGVIHVNMMSTVELS-DYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEdYGPMVVHCSAGVGRTGTYVVI
.. |....| |.|..... . . ....| . .. | |.| | ||.|..|||||||.| .|||...|. . |. ||.|||||||||||||.|.|
eesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts.sgpivVhCsaGvgRtgtfvti
DAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
| |.....| .||. . | .|| || ||| ..|| |....||.|
diilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 7-278 | 1.4e-89 | 295.0 | In-house | 3-276 (281) | alignment | ||
Range on Protein: 7-278
Range on HMM: 3-276/281.0
EEHVRRLHANGELLFSQEYGAFRS-PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWR
..|...|..| . | .|| .... |.. | ...|. ||||.||.|.|. || ..| | . ..||||||...||....||||.|||.|.....||.
rkhlkqlsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWq
MVWEQNSRVIVMVTNCEERGRIKCHQYWPSSG-SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSpEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSA
|||||. ..|||||. | |..|||.||| . .|| ..|..... | . | | | ..|... |.| | | .||||||||||.. . .|.| ..
mvweqkvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresg.etreveqlaytaWPdhGvPattkellefrkevlk
VNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAE-ATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
.. .. |.|.||||||||||||. .| .|...|| ...|| . |. || .|||||| || .. ..|.|.
ltekktkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldal
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 329-576 | 2.3e-89 | 293.9 | In-house | 4-250 (250) | alignment | ||
Range on Protein: 329-576
Range on HMM: 4-250/250.0
ANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVkVHRYWPGKQP
|. | ||.|||||.....| .|| | . . |||||| ...||. .|||||||.|...|| |||||..|.. |||||.. ||.|. .|.||| ...
akkpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPveka
TSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERL
. |.. |..| ...| ||..|..|....|.. .|.|||..|..||| | |. ..|. .||. ||..| . |.|||||||.| |.|.. ..|||
ekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvqasqqqagnaPvivqCsaGvgrsGafiaidavlerl
KAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPYNN
| | .||||. .|.||..|| .|...||| |.|. . ..| |.. |..
kkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkaldsvedyar
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 306-572 | 1.6e-88 | 291.8 | In-house | 21-287 (305) | alignment | ||
Range on Protein: 306-572
Range on HMM: 21-287/305.0
QTEMDAEFQRLSRNkapPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTI
.....|... | .. ..... . .||.|||.... ..|| |..|| . .. ||||||.|.||| .||..|..|.|...|. ||||.|.| ||
dkgleaqykslyee...eesidvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvsti
VMLSQEMESGKVKVHRYWPGKQPT--SIGNLVVEMLHDKQFDDYIMREFKVTN-TKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQ
|||.. .| || | ..|||... .|...||. |.. |||.|..|... ... ||.| |||.| ||| | |.. . |..|| .||. |.| .
vmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkdqkkdkgv
LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFD
|||||||||||||.||.| .||||.| .||||. .||||..|. ||||..|| |... | |.....|
pllVhCsagvgRtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgd
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 304-564 | 1.7e-88 | 291.4 | In-house | 18-275 (288) | alignment | ||
Range on Protein: 304-564
Range on HMM: 18-275/288.0
TGQTEMDAEFQRLSRNKAPpSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCC
...|.. |.. |. . .. . ..|.||..|||| |.|||| .||.|. ..|.|||||.||||. .||..||||.|..||. |||....|..
rnrtgfseeynsLaalekt.ksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenkts
TIVMLSQEMESGKVKVHRYWPGKQ-PTSIGNLVVEMLHDKQFDDYIMREFKVTntKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgVQ
|||||.. .| || | ..||| .. |. |.. |.....|. .|...|.. . |. . . |||..|||| | |.| |..|. ||. .|. ..
tivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrkllle..kkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad.tg
LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
|||||||||||.| |. ||.....| ..||. ||..||.||. .|||..||||.|..|
piivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevl
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 8-278 | 4.6e-88 | 290.0 | In-house | 10-279 (288) | alignment | ||
Range on Protein: 8-278
Range on HMM: 10-279/288.0
EHVRRLHANGELLFSQEYGAFRSPDTVT-SHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRM
..| . .|... ||.|| . . . .. . . | ||||.|| ..|. || |. | ...|||||.|.||..|...|||.||||..| .|||..
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWel
VWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS-QNYGVIHVNMMSTVELSDYTIRSFGVKRSGspEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSaV
|.|... |||.|. |.|. ||..|||... .||| . | .... || |.. |.. ..... .|. . ||.|.||||||||.| . .|...|. |
vyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkk..teleitqyqylaWpdhgvPeskapllellrqvk.v
NLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
. ..| ||..||||||||||||....|| ......| ..|| . | || ||.|.||.. ||. |..|||. |
anqadtgpiivhCsaGvGrtgtFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 1-313 | 6.1e-88 | 289.8 | In-house | 6-314 (315) | alignment | ||
Range on Protein: 1-313
Range on HMM: 6-314/315.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
||.|.. .| . .|. . | |.| . . . . . |. |||| || |.|. || | .| || |||.|||..||| |.| |||||||....
ipldqlityvaqkkastkngfkqdyesipggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasv
HDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSgSQNYGVIHVNMMSTVELSDYTIRSFGVKRsGSpEERMVLQYHYTAWPDHGVPNSVTSVLNFVR
.||||.|.|.. |||.|| |. . |. .||| || | | ..| ..||.|.. | |. . | |.|.|||.||| |||.. ....|..|
kdfwrlvfeedigkivmltnlvegekrkaekywpdk.kviyGkitvtrkseevnteytvrtlsvvf.gd.nirevvqlhytswpdmgvpkytiplmnlir
KSSAVNlTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRP
. . |.. |..|||||||||||||.. .|| |....|| .||||.. .| .| |||| .|| .|.|.|||.. |||| | . || . |. |
tvkqhh.tnsvgaivvhcsaGvGrtGtfitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgdtsiaqdlylqrydsllap
STDTGQTEMDAEF
| ||| | .. .|
spdtgstllqeqf
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 293-568 | 3.2e-87 | 287.3 | In-house | 2-290 (297) | alignment | ||
Range on Protein: 293-568
Range on HMM: 2-290/297.0
RIKELMRPSTDTGQTEMDAEFQRLsRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPD
.|.||. ..|. . |.. . ||... .|. ..|..| .||||..|| ||.||| |. . .| |||||||..||| |||||||| |.. |. |
eieelvayvkekgkrGlskeyaei.rnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsd
FWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQP--TSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIG
||||.|||.. .||| . .| |..| .||| .. .. |.| |. ..... .|| .| ....|.|.. || | .||..||| | |.|. |.|..
fWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvle
QVQRWQQKCGVQLT------------AVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
.|.. | . .|. ||||||.|||| |... | ..||. ...|||..|||.||.|| ..|| |||||||... ||
kvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavleya
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 302-569 | 7.8e-87 | 286.3 | In-house | 20-287 (307) | alignment | ||
Range on Protein: 302-569
Range on HMM: 20-287/307.0
TDTGQTEmdaEFQRLSRNkAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQD
|| | .. |...| .. . . . .. |. |||| .. ..|.|||.|. .| ||||||..| || || ||| |.|. || ||||||.||.
tdfglak...eyekLear.eidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqe
CCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKE-----SASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQ
.|||||.. | . |...||| . . |...|.. . .. .|||.||..|...|| .|| | ||..|.|.| |.. ||..|| ||. .
vtlivmlsnlteknrkkcakYWpiedevqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrely
QKCgVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
.. |||||||||.|.| |...|...|||| ||.|.|||.||.||. .|| |||.|.|. | .| .
kln.rsPivvhCsaGvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyss
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 38-278 | 3e-86 | 284.3 | In-house | 5-246 (249) | alignment | ||
Range on Protein: 38-278
Range on HMM: 5-246/249.0
HSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSG
..| ..|. |||| .| ..||.|| |....| . ||||||.|.|||. .|..||.|||||||..|||||.||....||||.|...|.||.||.||||..|
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywplgg
SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTE-DYGPMVVHCSAGVGRTGTYVVIDAQLK
|..|| ..|...|. ...|||.| . ..... .|.|.||...|| ||||||| |. ..|.|... .. . . ||..||||||||||||..... |
sleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmle
RIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
... | .||....| .|| ||. .|| ..||. ....||| .
qlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 3-276 | 9.6e-86 | 282.5 | In-house | 3-288 (297) | alignment | ||
Range on Protein: 3-276
Range on HMM: 3-288/297.0
VDEFEEHVRRLHANGellFSQEYGAFRS-PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCH
..|....|. . .| |.|| . |. | . | ..| .|| ||||... .|. || |. ...|..|||||||..|||.... .||.||||..|..
ieelvayvkekgkrG...lskeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvs
DFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWP--SSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV
|||||||||. .||||.| ..||||.|| |||| . |...| ..|. ....| .||..|.. .|.. |.| | . ...|||.|||.| .|.|...
dfWrmvWeqevlvivmttrvvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvl
R---KS--SAV-NLTED------YGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
. . .|| .|... |.|||||||.|||||.. .| |.|.. ..|||| . | .|| || ..|...||.. . .||
ekvrekqalavkelgdewkghpsgPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavle
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 44-276 | 1.6e-85 | 281.6 | Pfam-A | 1-235 (235) | alignment | ||
Range on Protein: 44-276
Range on HMM: 1-235/235.0
NRFKNRYNNITAFDHCRVLLqpiEGDPT-SDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWP--SSGSQN
|. ||||..|...|. || | .|... ||||||||..||......||.||||..|..|||||||.....||||.|..||.|| ||.|||| ...|..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGVIHVNMM-STV-ELSDYTIRSFGVKRSGSP-EERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNlTEDYGPMVVHCSAGVGRTGTYVVIDAQLKR
|| |.|... .. . ..||.| . .| .... |.|.| |.|||.|||||||.|..|.|...|| . ... ||.|||||||||||||.|..|. |..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleq
IQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
..|| .|||...| .|| ||. ||| ..||. .....||
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 44-276 | 1.6e-85 | 281.6 | In-house | 1-235 (235) | alignment | ||
Range on Protein: 44-276
Range on HMM: 1-235/235.0
NRFKNRYNNITAFDHCRVLLqpiEGDPT-SDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWP--SSGSQN
|. ||||..|...|. || | .|... ||||||||..||......||.||||..|..|||||||.....||||.|..||.|| ||.|||| ...|..
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGVIHVNMM-STV-ELSDYTIRSFGVKRSGSP-EERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNlTEDYGPMVVHCSAGVGRTGTYVVIDAQLKR
|| |.|... .. . ..||.| . .| .... |.|.| |.|||.|||||||.|..|.|...|| . ... ||.|||||||||||||.|..|. |..
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleq
IQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
..|| .|||...| .|| ||. ||| ..||. .....||
leaeeevdvlqivkelRkqRpgmvqsleqYiflykaile
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 285-567 | 4.1e-85 | 280.9 | In-house | 11-291 (319) | alignment | ||
Range on Protein: 285-567
Range on HMM: 11-291/319.0
IQARDLRQRIKEL-MRPSTDTGQTEMDAEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQ
. .|.. ..| . | .|.. .||.|... .. .. . |||. || |||. |.|..| ..|.| |.|||||| ...|| .|. .||.|
vavpdfpayyqqlsnksdfdddltklevefrracklgvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaq
APIPDTIPDFWRMIWEQDCCTIVMLSqemesgKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTN-TKESASRVVRQYQFTAWPDIGSPDSG
| ..|. ||||||||..|.|||.|. | | .||| | .. |.. .. ..|..|...... .|| | ..|. | ||| | ||..
GPldntladfWrmiweyncstivllt......kdkcsqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdyp
GGLIDLIGQVQRWQQKCG-VQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGE-Y
|. |. .|. ..| . ||||||||||||. .. .|..|.| | .|||...|..||.||. .|| || |.| .| | .
sdlmrlvkkvrhltskenhranivvhcsaGvGrtGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 320-570 | 7.7e-85 | 279.9 | In-house | 19-274 (278) | alignment | ||
Range on Protein: 320-570
Range on HMM: 19-274/278.0
KAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRltmqavtegsDYINANYIDGYmsKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKV
.||.. |... |..|||| ..|||| .||. |||||.||||| .|.|||||.| |.|. |||||.||... .|||| ...| |..|
lgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekc
HRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNT----KESASRVVRQYQFTAWPDIGSPDSG--GGLIDLIGQVQRWQQ--------------KC
..||| ... .|...|..| ...|||..| ..|||. .. || |...... ||| |.|.. ...|. ....... .
aqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsg
gvQLTAVHCSAGVGRTGVFCAVSILIERLkaEAMVDVFQTVKQLREQRPA-MVQTKEQYEFCYQTLGEYLHS
..|||||||||||...|. ...|.| | ||....||.||.||| .||..|||.|.|. | |.|.
..gpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllr
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 39-277 | 1.2e-84 | 278.9 | In-house | 4-242 (245) | alignment | ||
Range on Protein: 39-277
Range on HMM: 4-242/245.0
SLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS
.| ..|. |||| .| ..||.|| |.|..||. ||||||.| |||| . .||.|||||||..|||||.||.....|||.|..||.||.||.||||...|
allpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplges
QNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRI
..|| ..|...|. |.|||.| . |.. |..|.|.|..|||. |||||||... ..|.|.. . . ||..||||||||||||..... | ..
ltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleql
QAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEA
..| .|.... | .|| || .|| ..||. ....|||
ekelgvsleeavkelrsqRpgavqtpsqyrflyeallel
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 327-568 | 1.2e-84 | 278.9 | In-house | 2-243 (245) | alignment | ||
Range on Protein: 327-568
Range on HMM: 2-243/245.0
QSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGK
..|.||.||.|||| ..||||.|||.|. ..||||||.|.||| .. |||||.| |.|..|||||.||... |||||..|.| |.|| ..||| .
svallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywplg
QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIE
... .|...|..| ...|||..|...|||.... || |..|... ||| | ||. |.|.. |........ ..|||||||||||.|.|. ...|
esltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalaedsngpvlVHCsaGvgRtGtfiaaylmle
RLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
.|..| |.....||.||.||| .||| .||.|.|. | |.|
qlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 326-568 | 2.4e-84 | 278.1 | In-house | 3-246 (249) | alignment | ||
Range on Protein: 326-568
Range on HMM: 3-246/249.0
FQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPG
. |.||.||.|||| ..|||| .||.|. ..||||||.||||| .|..|||||.| |.|..|||||.||... .||||....| |..| ..|||
ysvallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl
KQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKC-GVQLTAVHCSAGVGRTGVFCAVSIL
.... .|...|..|. ...|||..|....||.... || |...|.| ||| | |.| |.|.| .|. ..... ..|||||||||||.|.| ..
ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylm
IERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
.|.|. | ||....||.||.||| .||. |||.|.|. | |.|
leqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallell
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 334-564 | 2.9e-84 | 277.5 | Pfam-A | 1-233 (235) | alignment | ||
Range on Protein: 334-564
Range on HMM: 1-233/235.0
NKHKNRYANVLPYDDTRVRLtmQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWP--GKQPTSI
||.|||| ..||||.|||.| . .. ||||||||..|| .||.|||||.|...|| |||||.|.... .|||| ...|.|..|...||| .....
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GNLVVEML-HDK-QFDDYIMREFKVTNTKES-ASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQqKCGVQLTAVHCSAGVGRTGVFCAVSILIERL
|.. ||. . | . ..|..|.......||. ..| |.|...|.||| | |.| .|.||| .|.... . . . |||||||||||.|.|..||.|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleql
KAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
.|| |||.|.||.||.||| |||. |||.|.|...
eaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 334-564 | 2.9e-84 | 277.5 | In-house | 1-233 (235) | alignment | ||
Range on Protein: 334-564
Range on HMM: 1-233/235.0
NKHKNRYANVLPYDDTRVRLtmQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWP--GKQPTSI
||.|||| ..||||.|||.| . .. ||||||||..|| .||.|||||.|...|| |||||.|.... .|||| ...|.|..|...||| .....
nkkknRykdilpydktrvkl..kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslty
GNLVVEML-HDK-QFDDYIMREFKVTNTKES-ASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQqKCGVQLTAVHCSAGVGRTGVFCAVSILIERL
|.. ||. . | . ..|..|.......||. ..| |.|...|.||| | |.| .|.||| .|.... . . . |||||||||||.|.|..||.|.|
gdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk.eaksgpvvVhCsaGvgRtgtfvaldilleql
KAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
.|| |||.|.||.||.||| |||. |||.|.|...
eaeeevdvlqivkelRkqRpgmvqsleqYiflykai
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 32-275 | 5.8e-84 | 276.7 | In-house | 42-294 (306) | alignment | ||
Range on Protein: 32-275
Range on HMM: 42-294/306.0
DTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQpIEGDPTSDYINANYLDGY--RKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKC
.... ... . |. ||||.|| ||| || |. .. | ||||||||... ....|||.|| |..| |||||||..|||||||.|. |||. ||
kllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgkekC
HQYWPSSGS-QNYGVIHVNMMSTVELSDYTIRSFGVK-RSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNL---TEDYGPMVVHCSAGVGR
.|||.. . ..||.|.|...| .|.||..|.. |. .. . ||| | |||...|||||||.. ||.|... .. . ... ||.|||||||.||
arYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGR
TGTYVVIDAQLKRIQ---AEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLL
|||..|||. || |. .| .|... |...| ||. .||.|.|| ... ..
tGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaik
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 283-570 | 8.9e-84 | 276.1 | In-house | 2-299 (306) | alignment | ||
Range on Protein: 283-570
Range on HMM: 2-299/306.0
TEIQARDLRQRIKELMRPSTDTGQTEMDAEFQRLSRNKAPP-SKFQSANLPVNKHKNRYANVLPYDDTRVRLTmQAVTEGSDYINANYIDGYM--SKKAF
|.. |....||..|| . ....... . ||..|....| . . .. | ||.|||| |.||.|.||| |. . . ||||||||||.. . |.|..
tsllakeieqrvselekeeeslekagfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksy
IATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQ-PTSIGNLVVEMLHDKQFDDYIMREFKVT-NTKESASRVVRQYQFTAWPDIG
|||| ...|..|||||.|.... |||. .|.| || | |||| .. .. |.. |.....|. .|||.||..|. ..|.. .| |.||.|..||| |
iatqgclettvsdFWrmvwqensrvivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhg
SPDSGGGLIDLIGQVQRWQQKCG---VQLTAVHCSAGVGRTGVFCAVSILIERLK---AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHS
| . | ..|.. .|.| |... . ||||||.|||| | . ||.. .. .| .|. ..||..|||| .|||..|| | |... .|...
vpkdpgavLdfledvnrkqeeleeaeagpivvhCsaGiGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyiet
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 302-569 | 2.9e-83 | 274.2 | In-house | 10-277 (281) | alignment | ||
Range on Protein: 302-569
Range on HMM: 10-277/281.0
TDTGQTEMDAEFQRLSR-NKAPPSkfQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQ
.. .. . |.. |. . .. .... . |..|||| |. || |||..| . .. .||||||...|| ..|..||||.|.|... .||.|.|||
sqndnaGfieeyeklaaigvdnta..taskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweq
DCCTIVMLSQEMESGKVKVHRYWPGKQ-PTSIGNLVVEMLHDKQFDDYIMREFKVtNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKC
. ..|||. .|.|.||.| ||||| .. ...|...|.... .. || |.||. ..... .| |.| ..||||| | |.. |.. .|.. ..|
kvsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkl.eresgetreveqlaytaWPdhGvPattkellefrkevlkltekk
GVQLTAVHCSAGVGRTGVFCAVSILIERLKAE-AMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
. .||||||||||.. |. |.....|| ...|| ..|..||..| |||| |||| |... ..|.
tkaplvihCsaGvGrtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldald
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 31-282 | 7.8e-83 | 273.3 | In-house | 20-276 (278) | alignment | ||
Range on Protein: 31-282
Range on HMM: 20-276/278.0
PDTVTSHHSLNQANRFKNRYNNITAFDHCRVLlqpiegdptsDYINANYLDGYrkQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCH
.. . ..| |. |||| .| ..||.|| |||||.|.||| ....||.|||||.|..|||||.||....||||.|...|.||.||.
gipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelgrekca
QYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRS----GSPEERMVLQYHYTAWPDHGVPNSV--TSVLNFVRKSSAVNL------------TEDYG
||||..||..|| ..|...|. .|.|||.| . | . |.| | ..||. |||||||.. .|.|.... ... .. |
qywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllsslllldsgg
PMVVHCSAGVGRTGTYVVIDAQLKRIqaEATVDVYNYVMMLRGQRNL-MVQVEDQYVLIHDVLLEAIACGD
|..||||||||||||.|... |... | .||....| .|| ||. .|| ..||. ....||| . .|.
pvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrgk
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 308-568 | 2.5e-82 | 271.0 | In-house | 9-277 (290) | alignment | ||
Range on Protein: 308-568
Range on HMM: 9-277/290.0
EMDAEFQRLSRNKAP--P---SKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDC
|. .|||.| . .. . .... ..|..|||| ..|||| .|| |. . .|||||||||.| | .|...||.|.|.|.|. ||||||||..
efakefqklkklsekykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknv
CTIVMLSQEMESGKVKVHRYWPGKQPTSI--GNLVVEMLHDKQFD-DYIMREFKVTNTKEsaSRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKC
.||. .|.| || | .|||| .. ... |.. |.. ..|..| |...| .||.. || ||.|.|...||||| | | | |..|| .|.. |..
eivvmaCrevelgkkkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqke..srkvyqfhYtaWPDhgvPssaksllelielvrelqese
GVQLtAVHCSAGVGRTGVFCAVSILIERLKAEAM---VDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
. | .|||||||||||. .|. . | |||| . .|||. | .||.||.|.||||||||. |... |..
daPl.vvhCsaGvGrtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 4-292 | 3.1e-82 | 271.4 | In-house | 5-293 (439) | alignment | ||
Range on Protein: 4-292
Range on HMM: 5-293/439.0
DEFEEHVRRLHANGELLFSQEYGAFR--SPD-TVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
|||.||| .|. | . .|.... ||| .. . .. .. ||||....|||| || || | | | | ||||||..|| ... |||.||| ||.
defqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkett
HDFWRMVWEQNSRVIVMVTNCEERGRikchqYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGV--KRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNF
.||||.|.|... |||.|| | . ||||.. || | | . .|| .|.|| | | .| . || |||.||.||||. || . ||.|
ddfwrlviekktvtivmltnlvesyk.....ywpsdaevcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldf
VRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQ
.| . | .|.|||.||||||||||||| . .| |.....| ||. | .|| ||. ||| |||.|.. .|| | ||. .. ....
lrainsandkeeygpvvvhcsagvGrtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyGdiavtidefkk
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 311-567 | 5.4e-82 | 270.5 | In-house | 2-255 (284) | alignment | ||
Range on Protein: 311-567
Range on HMM: 2-255/284.0
AEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSq
.||.|... .. .. . |||. || |||. ..|..| ..|.| |.|||||| .| || .|. .|||| | ..|. ||||||||..|.|||.|.
vefrracklgvngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt.
emesgKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTN-TKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCG-VQLTAVHC
| | .||| | .. |.. .. ..|..|...... .|| | .||. | ||| | ||.. |. |. .|. ..| . |||
.....kdkcsqywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhc
SAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGE-Y
|||||||||. .. .|..|.| | .|||...|..||.||. .|| || |.| .| | .
sagvgrtgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleeh
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 30-296 | 1.3e-80 | 266.1 | In-house | 47-309 (319) | alignment | ||
Range on Protein: 30-296
Range on HMM: 47-309/319.0
SPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTnceergRIKC
... . .. . |. |||. || |||. .| |....| |||||| ...||... ||||||||..| |||||.||.|. ||..| . ||
gvnladqtfanldqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkc
HQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG-SPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSS-AVNLTEDYGPMVVHCSAGVGRTGT
|||| . .... .|.. | | ..|..|.. . . | . | . |.|. |||.|||.. . .. .|.| . . .. ..||||||||||||.
sqywplkivikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGrtGv
YVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKE
|.|.|. |.|.. | |||||.| || ||| .|| || .|. ||| | ... |. ..|
yivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvampdfpaylee
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 1-316 | 2.6e-80 | 264.6 | In-house | 3-315 (315) | alignment | ||
Range on Protein: 1-316
Range on HMM: 3-315/315.0
IPVDEFEEHVRRLHanGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETC
||| .| | . . |||.|. . ||. . . .. | ||||.|| .|. || |. |. .| |||||| |. .. ... |||.||||. .
ipvaqfpafvnknr..htalfseefhdlpdPdiyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasv
HDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPS--SGSQNYGVIHVNMMSTVELSDYTIRSFgVKRSGSpEERMVLQYHYTAWPDHGVPNSVTSVLNF
||||||.... |||||. .| .||| |||| . | ..| |.|...|. .| ..| . | | . | | | |...| |||.||.. ..|.|..
ddfwrmvlqekvttivmvtkkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarkl.vtrkse.esrtvtqfqftewPdkGvdkqtssllkl
VRKSSAVNLTEDYgPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELM
... | | .... ...||||||||||| . || ...|. . .|||.|.| .|| .| .|| |..| .|.|..|| . .| | . .....|
ikevkadngkkef.sllvhcsaGvGrtGvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledllwrntlilvihftdhlqdlh
RPSTDTGQTEMDAEFQRL
. .|...| ||..|
tsvdgsgrskmtkefetl
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 27-278 | 5.1e-80 | 263.5 | In-house | 23-277 (290) | alignment | ||
Range on Protein: 27-278
Range on HMM: 23-277/290.0
AFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGR
.... ........ .. |. |||| .| .|. || |. ||... |||||||.. | .. ||||||||||.| .|||||.||.| ...||. . | |.
kykaekvysteagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgk
IKCHQYWPSSGSQN--YGVIHVNMMSTVELS-DYTIRSFGVKRSgsPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLtEDYGPMVVHCSAGVG
.||..|||..| .. .| ..|.... .. |..||.. |... |.|.| |.|||||||||||.|..|.|..... .. .. |.|||||||||
kkCerYWpeegeeelefgefevtleeekavdddflirtLkveaq..kesrkvyqfhYtaWPDhgvPssaksllelielvrelqe.sedaPlvvhCsaGvG
RTGTYVVIDAQLKRIQAEAT---VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
|||| ..|| . ..|| . .||.. |. || ||. .|| ..||.|.. ..| .
rtGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelv
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 328-565 | 8.6e-80 | 262.9 | In-house | 37-274 (314) | alignment | ||
Range on Protein: 328-565
Range on HMM: 37-274/314.0
SANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQ
.|. |..|||. ..|.|| .||.|. ||||||..||.| .|||.|| |...|. ||||......|..||||.. .| |.|| .||| .
aakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrvkClkyWPedt
PTsIGNLVVEMLHDKQFDDYIMREFKVTN--TKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKcGVQLTAVHCSAGVGRTGVFCAVSILI
. |.. ||... . ....| |.|.. . .. |.|||.||..||| . | | ||..|. .|. .|.. . . |||||| ||||.|.|..|..
ev.ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee.eaGrivvhCsaGaGrtGtfiaidivl
ERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLG
. .. | .||||..||.||.... ||.|.||| |.|. .
dmieregvvdvfnavktlrsrkvnmveteeqykfiydvil
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 32-297 | 1.3e-79 | 262.6 | In-house | 13-274 (284) | alignment | ||
Range on Protein: 32-297
Range on HMM: 13-274/284.0
DTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTnceergRIKCHQ
.. . .. . |. |||. .| |||. .| |... | |||||| .. ||... |||.||||..| |||||.||.|. ||..| . || |
ngtdqtfanldqnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsq
YWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG-SPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSS-AVNLTEDYGPMVVHCSAGVGRTGTYV
||| . .... .|.. | | ..|..|.. . . | . | . |.|. |||.|||.. . .. .|.| . . .. ..||||||||||||.|.
ywplkivikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgrtgvyi
VIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKEL
|.|. |.|.. | |||||.| || ||| .|| || .|. ||| | ... |. ..||
vldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalleehlfghsdvalpdfpayleel
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 304-570 | 9.6e-79 | 260.1 | In-house | 16-289 (563) | alignment | ||
Range on Protein: 304-570
Range on HMM: 16-289/563.0
TGQTEMDAEFQRLSRNKAPP-SKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGS-DYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQD
|.. ...||. | .. .. . .... | ||.|||| |...|| .||.|. . .... ||||||||||| .||||||| |..||. |||||||||
dgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqn
CCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTN-----TKE-SASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRW
.|||... |.|. | ..||| .. .|.| | . . ... | .|.... | .|. ..||||..| ||| |.|.. . . . ..
vaiivmitnlvergrrkcdvYWPkdesetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaa
QQKcGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHS
... . . |||||||||||...... |......| .|.||...|..| ||. .|||.||| | ...| | . |
nka.eaGPivvHcsaGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaias
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 327-567 | 5.3e-78 | 257.2 | In-house | 3-241 (243) | alignment | ||
Range on Protein: 327-567
Range on HMM: 3-241/243.0
QSANLPVNKHKNRYANVLPYDDTRVRLtmqavtEGSDYINANYIDGYmsKKaFIATQAPIPDTIPD----FWRMIWEQDCCTIVMLSQEMESGKVKVHRY
|.||.|..|||| ..||||..||.| |||||||||.|... .. .||||.| |.|. | ||||.||... .|||| ...| |..|...|
siallpenlsknrysdilpydhsrvkl......egsdyinanliyvt..pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqy
WPGKQptSIGNLVVEMLHDKQFDDYIMREFKVTNTK-ESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQK-------CGVQLTAVHCSAGVGR
|||.. .|...|..|. ...|||..|.....|.. . .| |..|....||| | ||| |.|.. .|. .... . ..|||||||||
wpgev..tygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgR
TGVFCAVSILIERLkaeaMVDVFQTVKQLREQRPA-MVQTKEQYEFCYQTLGEY
||...| .....| ||....||.|||||| .||| .||.|.|. | |.
tGtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 1-280 | 1.3e-77 | 255.6 | In-house | 2-285 (290) | alignment | ||
Range on Protein: 1-280
Range on HMM: 2-285/290.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRSPD-TVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGD--PTSDYINANYLDGYRKQREYIAAQGPLP
||||.| |.| ||.|. | ...... | . | .. | . |. .||..|| | |. |.|| |. | .|||| |..||.....|||.|||..
ipvdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvs
ETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGS-PEERMVLQYHYTAWPDHG-VPNSVTSV
.| |||...|.... .|||.|| | |. ||.||||.|....|| ....... .|..|..| . || . | ....| ||. |.|...| |.| |..
ntlvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtil
LNFVRKSSAvNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIAC
| . . . . ...|||||..|||........ ... . | .||.. . .| |. .|| ..|| .|....|... .
lvieemykt.qrkrgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 301-574 | 1.3e-77 | 255.6 | In-house | 14-289 (290) | alignment | ||
Range on Protein: 301-574
Range on HMM: 14-289/290.0
STDTGQTEMDAEFQRLSRNKApPSKFQSANLPVNKHKNRYANVLPYDDTRVRLT-MQAVTE-GSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIW
. .|.. . ..|..| . . . . .. . ||..||.||...||| |. | .. . .|||| ||.|| ||..||||.|...|. |||..||
ghakgnegfrnqfkmldsges.ehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliw
EQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKE-SASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQ
..... |||| ...|.|||| . ||| .. ...|. ...|.......|| |...|.|... |.. | |||.|.|.. |. . . .| .... |
qekvtiivmltniieegkvkCqqYWpdsdtkaygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyktqr
KCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPY
| | . ||||..|||..||||. . |.. | | .|||| .|..| |.| .|||..||.. .| . .||.||. |
krgntsivvHCSdtvgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltyldsfety
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 38-276 | 2e-77 | 255.3 | In-house | 4-240 (243) | alignment | ||
Range on Protein: 38-276
Range on HMM: 4-240/243.0
HSLNQANRFKNRYNNITAFDHCRVLLqpiegDPtSDYINANYLDGYRKqreYIAAQGPLPETCHD----FWRMVWEQNSRVIVMVTNCEERGRIKCHQYW
..| ..|. |||| .| ..|| || | .. |||||||. ..... .|| |||||||..| ||||.||....||||.|...|.||.||.|||
iallpenlsknrysdilpydhsrvkl.....eg.sdyinanliyvtpr...liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqyw
PssGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG-SPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLT-------EDYGPMVVHCSAGVGRT
| |...|| ..|...|. .|.|||.| . ... . ....|.| .|||..|||||||.|....|.|... .. . ||..||||||||||
p..gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRt
GTYVVIDAQLKRIqaeaTVDVYNYVMMLRGQRNL-MVQVEDQYVLIHDVLLE
||..... |... .||....| .|| ||. .|| ..||. ....|||
Gtliaaylmllll....gvdleeavkllreqRpgkavqtpsqyrflyealle
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 294-577 | 5.7e-77 | 253.5 | In-house | 7-287 (287) | alignment | ||
Range on Protein: 294-577
Range on HMM: 7-287/287.0
IKELMRPSTDTGQTEMDAEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTmqavTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDF
. |... ...|... |. | . . . . . . ||.|||....|..|. || | | ||||| .|||| .|||||....|. .|. .|
fgefvakghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnf
WRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTK-ESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQV
|..|... .||||.||.|. . . ..||| .. ...|. .|.|.... ..||.|...|.|.. ... . |.|||.|.|.. | . . .| .
WkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieem
QRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPYNNF
. |.| | ||||..|||...|||. . |.. | | .|||| .|. | |.| .||| |||.| .. . |||.||. | .|
yktqrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetysdf
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 19-324 | 8.5e-77 | 253.4 | In-house | 18-323 (515) | alignment | ||
Range on Protein: 19-324
Range on HMM: 18-323/515.0
LLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMV
|||.|. . |. . .. | ||||.|| .| || |. |. .| |||.|| |. .. .. |||.|||.. . ||||.|...| |.||
tlfseefhdlpgpniypqtvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamv
TNCEERGRIKCHQYWPS--SGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSpeERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDyGPMVV
|. .| .||| .||| . | ..| |.|...|. .. ..| . | .. | | |.|.| |||.|||. .|.| .... | . |...
tklkegdkikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgdd..srtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt.hplii
HCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRPSTDTGQTEMDAEFQRL
|||||||||| .. || . ... .|||.|.| .| .| .|| ..|| .|....|| . .| | . . ...| |.. | ||| |
hcsaGvGrtGvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledllwrntlipvihftdhlqdlhssgdgrgrskmtkefqtl
-SRNKAPPS
| ||.
kslcpdppa
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 4-313 | 4.4e-75 | 247.8 | In-house | 8-323 (325) | alignment | ||
Range on Protein: 4-313
Range on HMM: 8-323/325.0
DEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDF
.. ||| . .|. . |..|.| | |... . . .|. |||..|. |.|. || |. . || ||||||.|| ..|. ..||| ||..| .|.
vnlvehvekkkaqdqdgfahefgllpsddgiakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindl
WRMV--WEqnSRVIvMVTNCEERGRIKCHQYWPSS--GSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV
||.| |. . |. .|.| . | .| .||| |...| ..|.... |.||| | . ||. | | | |... .|.| ||.. .......
WrlvldWr..csvv.vvlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisil
RKSSAV----NL-TEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRI
. || . |. .|..|||||||||||... . . |... |. ||....| || .| ||. |||.||.. | ||. .|.|.. . ..
qlvkavservtantkastpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeakl
KELMRPSTDTGQTEMDAEF
| | . ... ||
sslqernpltqklniekef
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 322-569 | 1e-74 | 246.3 | In-house | 32-278 (315) | alignment | ||
Range on Protein: 322-569
Range on HMM: 32-278/315.0
PPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHR
.... ..| ..| .|||| |.||.| .||.| . . |||||| || .. . ||.||.|.| . .. |||||..... ||||... |. |.| .
diyrqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdkikcrq
YWPG--KQPTSIGNLVVEMLHDKQFDDYIMREFkVTnTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLtAVHCSAGVGRTGVFC
||| . . |.. ||.| .. | ..|.. || | .|| | |.||| ||| |.. . |. || .|. ..| | ||||||||||||..
ywPdrkadsvefGsikvellsleadtdgvarkl.vt.rkseesrtvtqfqftewPdkGvdkqtssllklikevkadngkkefsl.lvhcsaGvGrtGvvi
AVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
.. ....| . .||||..||.||..|| .|||.|.| | |... |.|.
sidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 43-276 | 2.5e-74 | 244.5 | In-house | 2-237 (237) | alignment | ||
Range on Protein: 43-276
Range on HMM: 2-237/237.0
ANRFKNRYNNITAFDHCRVLLQPIEGDptSDYINANYLDGYRK-QREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSG-SQN
|. |||| ||.|.||.||.|. .. ||||||.||.|. ..|||||||| .|.|||.|||... ||||.| |. ..|||.||||. .
enkiknrygnivaydhsrvvlkgagsg..sdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaa
YGVIHVNMMSTVELSDYTIRSFGVKRSG-SPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVN-LTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRI
|||. | . |.||||.||. . . . | |.. ||..|.|||.|||. ...| | .. . . || ..|||||||||| ..|||| |..
ygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqa
QAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
. . ||.|||| . .| ..|..||||.||...||
kekkvvdiynyvysieedrpyiiqtkdqyvfihqtile
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 1-285 | 2.7e-74 | 244.7 | In-house | 2-285 (287) | alignment | ||
Range on Protein: 1-285
Range on HMM: 2-285/287.0
IPVDEFEEHVRRLHANGELLFSQEYGAFRS----PDTVTshHSLNQANRFKNRYNNITAFDHCRVLLQpiegDPTSDYINANYLDGYRKQREYIAAQGPL
|||..| | |.. ||.|. |.. . . . .| || |.. . |. |||...| | ||||. . ||||| ..|||......|.|..|.
ipvekfgefvakghakgnegfknqftvleqvtqredevt..hniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPm
PETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG-SPEERMVLQYHYTAWPDHG-VPNSVTS
.| .||......| .|||... .| . .|.||||.. | .| ...... ..|..| . ||... . ....| ||..|.|...| |.. |.
fntarnfWkliddrnvtaivmlcqekendeevcyqyWpeeksvvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqti
VLNFVRKSSAvNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEI
.| . .. . . . ...|||||..|||..... .. ... . | ..||.. . | |. .|| .|| | |..|| . ...|
llvieemykt.qrkrgntsivvhCsdtvGrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleyldsfetys
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 306-572 | 1.5e-73 | 242.5 | In-house | 20-288 (297) | alignment | ||
Range on Protein: 306-572
Range on HMM: 20-288/297.0
QTEMDAEFQRLSRNKAPPSKFQSANLPVNK---HKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSkkAFIATQAPIPDTIPDFWRMIWEQDC
|....... . .. | .. |.. .| .|.||.|.|||| ||.| . |||.|| .. |. .|.|| | ..|. |||.|.....
qknrhtdvfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqv
CTIVMLSQEMESGKvKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPD--SGGGLIDLIGQVQRWQQKCG
|||||... |. | | |||. | |. |...|..| .. .| ||..||. | | |||.||||. ||| . | |..|| .|. ..
stivmlnddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqna
VQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFD
|||.||||||||.... . . | | ||.|..||.||..|| .|||||||.| |... |.| | |
egPllvhclaGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsed
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 17-277 | 2.7e-73 | 241.3 | In-house | 15-274 (280) | alignment | ||
Range on Protein: 17-277
Range on HMM: 15-274/280.0
GELLFSQEYgAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQpieGDPTsDYINANYLD----GYRKQREYIAAQGPLPETCHDFWRMVWEQNS
|..| . | .| .. ... .| |||| .|...|. || |. .| |||||||.. . |||.||||..|..|||.|||||.|
Gavlaqfeq.lyrkkpglaisaarkpenlsknryrdilpydatrvklk...eset.dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqks
RVIVMVTNCEERGRIKCHQYWPSSG-SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDy
..|||.|. ||||.|||||||... ...|| ..|.. .. | . | .| . .|.. . |||..|| |.||||||||.. ...|.||.. .. ...
slivmlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrsgke.
GPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEA
|.|||||||.|||| ..... | |.|. | . . | ..| || .|| ..|| .. . .|..
ePvvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 332-569 | 3.8e-73 | 241.3 | In-house | 41-277 (515) | alignment | ||
Range on Protein: 332-569
Range on HMM: 41-277/515.0
PVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTS-
.| .|||| |.|||| .||.| . |||.|| || .. . ||.||.|.| . .. ||||...... ||.|... |. |.| .||| | |
einfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdkpgdsv
-IGNLVVEMLHDKQFDDYIMREFKVTntKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLtAVHCSAGVGRTGVFCAVSILIERLK
|.. ||.. . . | |...|. |.. || | |..|| ||| |.| |. || .|. ... | .|||||||||||.... . . |
kfGsikvelvsleactggikrkltvl..kgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqythpl.iihcsaGvGrtGvvisidsvvahak
AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
|||||..|...|..|| .|||.||| | |... |.|.
ttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledll
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 42-277 | 4.6e-73 | 240.3 | In-house | 5-239 (239) | alignment | ||
Range on Protein: 42-277
Range on HMM: 5-239/239.0
QANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRK-QREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQn
. |. |||| || ..|| ||.|. . || ||||||.|| | . |||.|| . .. |||||.|.. ||||.| | . ||||||| | |.
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.
YGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEdYGPMVVHCSAGVGRTGTYVVIDAQLKRIQA
| ..| . | ..|| ||.| . . | ||| | |||.| |||.|||. |.|| . || . .| | |.||||||||||...|||| |.. .
ycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpg.arpwvihcsagvgrtgaflvidamlrqakk
EATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEA
. |||..||| .| .| ||| .|||.|| .|||
qktvdifnyvkairedrphmvqtseqyvfihlavlea
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 309-569 | 5.6e-73 | 240.4 | In-house | 7-269 (274) | alignment | ||
Range on Protein: 309-569
Range on HMM: 7-269/274.0
MDAEFQRLSRNKaPPskfQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEG-SDYINANYIDGYMS-KKAFIATQAPIPDTIPDFWRMIWEQDCCTIV
...|| | | .. . ... ...|||| ..|| . .|| |. . ... |.||||||| || .||..||| |.| |. ||||||..... ||
lekeflelPlnf.dq...eeldvfgsqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqviv
MLSQEMESGKVKVHRYWPGKQPT----SIGNLVVEMLHDKQFDDYIMREFKVTNTKEsaSRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQ
|| . |. . | ..|.| .. . |.. ... . .. .|| .|.. . .... .| | | .|.||| |||. |.||. .|.. ... .
mltklkeaneqkCavyfPdaedyeiserygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenak
LT--AVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
|. ||||||.||||.| |.|| . .|..| .|||...| .|| .| ||||.||||. ...| .||.
lapvvvhCsaGiGrtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 329-566 | 7.3e-73 | 240.2 | In-house | 44-277 (315) | alignment | ||
Range on Protein: 329-566
Range on HMM: 44-277/315.0
ANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKqP
|. ||.|||| |...|| .||.| . . ..|||.|||.|||| |. .||.|.| . .. ||||...|.|. .||||.. .| | |. .||| |
akkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegekrkaekywpdk.k
TSIGNLVVEMLHDKQFDDYIMREFKVTNtkESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgVQLTAVHCSAGVGRTGVFCAVSILIERL
|.. | . ......| .| . |. .. | | |...|.|||.| | . |..|| .|...... | ||||||||||| |.... .....
viyGkitvtrkseevnteytvrtlsvvf..gdnirevvqlhytswpdmgvpkytiplmnlirtvkqhhtns.vgaivvhcsaGvGrtGtfitldavldqa
KAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGE
.|| ..||.. ....|..| |||. |||.| |..| |
eaenaidvynfitgvrqnrikmvqvaeqyqfiydalle
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 44-276 | 1e-72 | 239.6 | In-house | 28-266 (274) | alignment | ||
Range on Protein: 44-276
Range on HMM: 28-266/274.0
NRFKNRYNNITAFDHCRVLLQPIEG-DPTSDYINANYLDGYRKQ-REYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS---
. ||||..| .. ||||.. .. |. |.||||||. ||... . |.|.|||||.| .|||||.......||||.|. .|. . ||..|.| . .
sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyei
-QNYGVIHVNMMSTVELSDYTIRSFGVKRSGSpeERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAV--NLTEDYGPMVVHCSAGVGRTGTYVVIDAQL
..|| ..... ..|| ||..|.. .| . . || | | ||.|||| .|......|..|.. . . .. .|.|||||||.|||| .. |. .
serygdveikvekiverndysvrklvlkyler..ersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiGrtGcfiaisiav
KRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
.....| .||| . | || .| ||| ..|| ||| .| .
rqlreeivvdvlkivcnlrldrGGmvqtseqyelihralcl
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 42-276 | 1.6e-72 | 238.6 | In-house | 6-239 (239) | alignment | ||
Range on Protein: 42-276
Range on HMM: 6-239/239.0
QANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRK-QREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQn
. |. |||| || ..|| ||.|. . || ||||||.|| | . |||.|| . .. |||||.|.. ||||.| | . ||||||| | |.
rvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdstsk.
YGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEdYGPMVVHCSAGVGRTGTYVVIDAQLKRIQA
| ..| . | ..|| ||.| . . | ||| | |||.| |||.|||. |.|| . || . .| | |.||||||||||...|||| |.. .
ycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkdslpg.arpwvihcsagvgrtgaflvidamlrqakk
EATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
. |||..||| .| .| ||| .|||.|| .||
qktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 20-288 | 4.1e-72 | 237.8 | In-house | 27-294 (297) | alignment | ||
Range on Protein: 20-288
Range on HMM: 27-294/297.0
LFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKqrEYIAAQGPLPETCHDFWRMVWEQNSRVIVMVT
.||.|. . . .. . .. | |.||.|| .| || |. .. || |||.|| .. |... ..|. | | ..| |||.||.... .|||..
vfseeflclpeaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmln
NCEERGRiKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPN--SVTSVLNFVRKSSAVNLTEDYGPMVVH
. .|| . || .||. .|....| . | ..|. | . . |.. |... . .|.| ||... |||. |.. |..|.|... . .. ||..||
ddnerdk.kcaryWsdkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaegPllvh
CSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQAR
|.||||||| .. || . ... | .||....| .|| .| .|| ..|| ... ..|||. . ||.|||
claGvGrtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavleallsedtriqas
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 35-278 | 4.9e-72 | 237.5 | In-house | 28-269 (273) | alignment | ||
Range on Protein: 35-278
Range on HMM: 28-269/273.0
TSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGdptsdYINANYLDGY--RKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQY
|.. . ...|. |||| |. .|. || |. | ||||... .. ||||.|||||||..|||.|||||...||.|||. |.|..|||.|
tcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvkchry
WPSSGSQNYGV---IHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAvnLTEDYGPMVVHCSAGVGRTGTYV
||.| ... | ..|... ...|.....|.. || | | | | | . ....|||||||.| ...|.||.. | .| ||.|||||||.||.||..
wPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrr..lqtdagPivvhcsaGiGrsGtli
VIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
.||. | |. . .|| . | || ||. .|| .|||.... ..||..
tidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 308-569 | 1e-71 | 236.4 | In-house | 12-270 (273) | alignment | ||
Range on Protein: 308-569
Range on HMM: 12-270/273.0
EMDAEFQRLSRNKaPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVtegsdYINANYIDGYMSKKAF--IATQAPIPDTIPDFWRMIWEQDCCTI
. . ||. | | | . .... ||.|||| ||||||.|||.| .. ||||..| . |. . ||.| |.|.|. |||.|.|||.. |
qPaeefkelrelk.pldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaevi
VMLSQEMESGKVKVHRYWPGK--QPTSIGN-LVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGvq
.|...| |.|||| ||||| . ... . | | ||.|. .. |.. .|...|.... ..|| | . .|..||| | | | |. .. .|.| |.. |
amvtlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrrlqtdag..
LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
.||||||.||.|.. .. .... .. . .|| ..|..||||| ..||||.|| |.|... | |.
PivvhcsaGiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 309-563 | 2.1e-70 | 231.9 | In-house | 17-270 (280) | alignment | ||
Range on Protein: 309-563
Range on HMM: 17-270/280.0
MDAEFQRLSRnKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVtegsDYINANYIDGYM----SKKAFIATQAPIPDTIPDFWRMIWEQDCCT
. |.|..| | | | . . |..| | .|||| ..||||.|||.|. . . |||||||.. . . .|||| |...| |||.|.|||.. .
vlaqfeqlyr.kkpglaisaarkpenlsknryrdilpydatrvklkeset....dyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqkssl
IVMLSQEMESGKVKVHRYWPGKQ-PTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQkCGVQL
|||| . .|.|.|| |.||| .. .. |.. |.. .... |..||. ....... .| . | |..|||| | ||. ..... .|.. .. .
ivmlttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrklrs.gkeeP
TAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQT
. ||||||.|||||. .. . . . |. | . . |...|.|| ..|||..||.| ..
vvvhCsaGigrtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCea
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 310-570 | 2.1e-69 | 229.2 | In-house | 26-290 (325) | alignment | ||
Range on Protein: 310-570
Range on HMM: 26-290/325.0
DAEFQRLSRNKapPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMI--WEqdcCTIVM
||. | . . .. | .| || |||. ||...| .|| | . ||||||.|. .. |. |.|.||| ..|| |.||.. |. |..|.
ahefgllpsdd..giakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWr...csvvv
LSQEMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGV----
. |.. || . ||| . . | | |.. ... ||..| ..| ..|. .| |.|.|. .|.|.| . || .. |. ...
vlneldlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantka
-QLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHS
||||||||||||| .. ..... |. ||.|. ||.||..||.||.| .|| ..|..| |.. |
stpilvhcsaGvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveayms
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 302-567 | 1.8e-68 | 225.5 | In-house | 10-279 (288) | alignment | ||
Range on Protein: 302-567
Range on HMM: 10-279/288.0
TDTGQTEMDAEFQRLSRNKAPPSKFQS-ANLPVNKHKNRYANVLPYDDTRVRLTmqavTEGSDYINANYIDGYMSK-KAFIATQAPIPDTIPDFWRMIWE
. |.|..|..|. | .... .. .| | .. .|||. ..|||| .|| | . ||||| .. . . |||||||.. |. |||.|..|
mldgktaldkkfkeleqkqdkearkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvye
QDCCTIVMLSQEMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQR---
| .|||| .. | || ||.|||| . .... |.| | . . .. . .. |..|.. ...| . |. |.|.||..| |.| . |......|.
qkssviVmllskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesaye
-WQQKCGVQLtAVHCSAGVGRTGVFCAVSILIERLK-AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
|.|. . | |||||||||||||. | .. |. . ..|. | |..||||| |||.|||..|.|. |.
avqrksktPl.vvhCsaGvgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 37-286 | 9e-68 | 223.1 | In-house | 25-281 (290) | alignment | ||
Range on Protein: 37-286
Range on HMM: 25-281/290.0
HHSLNQANRFKNRYNNITAFDHCRVLLQPIEGdptsDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSS
... ...|| .||| ... .||.|. |. . |||||. .. . .|.|| .|||||.|. ||.|||||.|. .||. .. |...|||.||||.
reaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqikcaqywPqg
GSQNYG-----VIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKS-SAVNLTEDYGPMVVHCSAGVGRTGTYVV
... ..|...|. . | ||.| . .. . | | .|..|||.||| |||.| .. |.|. | .. |..|.|| |.|||||.||.||...
eeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGiGrsGtfcl
IDAQLKRIQAEAT---VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIA--CGDTEIQ
.|. | .|... ||. . .. || .| ..| || . . .|| . ||. .|
vdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaileGakvikgdssvq
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 307-569 | 2.6e-67 | 221.6 | In-house | 10-278 (287) | alignment | ||
Range on Protein: 307-569
Range on HMM: 10-278/287.0
TEMDAEFQRLSRN-KAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMqAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTI
..|.|...| .. .. . |..|. . .|||||.|||.||||| |. |||||||||. .| ..||||.|.||. |. ||||...|. ...
ddvdkevdalkedsesstatfkaaeelaavkknryadvlPiddtrvllsa.egelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasv
VMLSQEMESGKVKVHRYWPGK-QPTSIGNLVVEMLH-DKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQV----QRWQQKC
.....|.| .. |...||| . .| .| | .| |.. .| .| ... . . .|||.|... .||| . . . ||| .. .| . ..
itmtreveearlkcykywPerevPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardas
GVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
.| ||...|.||.|.. |. .|..||. ||| ..| .|||.| |.||. |. . |..| | .
evGPlvvhddvGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealvtyyk
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 21-282 | 2.6e-66 | 218.3 | In-house | 19-294 (296) | alignment | ||
Range on Protein: 21-282
Range on HMM: 19-294/296.0
FSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTN
. .|. .. . . |.. || |||. .. .|. ||.|. ..|. .|||||| | |.. |..||| ..| || ..|||.|..... .|..|.
yklelkltprleigdCagglrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtk
CEERGRiKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRS----------GSPEERMVLQYHYTAWPD-HGVPNSVTSVLNFVRKSSAVNLT-
. . ....||| . ..|| | |..... .... .|| | ... . |.|.|.....| |. . || | .......|. .
tfdfak.mypsywpnkskeqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekv
---EDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGD
...||.||..| |..|.| |. ||| | .. | |||...| .|| .|. .|. ..| | ||||||. |.
dedpeegPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleavlcnk
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 43-276 | 4.4e-66 | 217.6 | In-house | 19-262 (270) | alignment | ||
Range on Protein: 43-276
Range on HMM: 19-262/270.0
ANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRK-QREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQ--
.. |||..| . || |...| |... ||||||. |. . ...||||.|||| | ..||||.||.... |||.|. ||.|| || .|||.. .
rgkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv
--NYGVIHVNMMSTVELSDYTIRSFGVKRSGSpEERMVlQYHYTAWPDHGVPNSVT------SVLNFVRKSSAVNLTEDY-GPMVVHCSAGVGRTGTYVV
..| |.| .|.. . | .. ....|. |.|.| ..|..|||||||.. ..|. .|. ... | .|..|||||||||||| ..
kledgkikvlalseekeegyiltrlrleekge.errlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaGvgRtGtlia
IDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
.| .. .. . ||| . . || .| .|| .|| ... ...|
lDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavve
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 333-568 | 2.9e-65 | 214.9 | In-house | 41-290 (296) | alignment | ||
Range on Protein: 333-568
Range on HMM: 41-290/296.0
VNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKvKVHRYWPGKQPTSIG
|. |||. .|.||| .|| |. | |||||| |.|... ||..| |.|| .|. .|||....... ..|.|..... | ... ||| |. . |
enreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnkskeqyg
NLVVEMLHDKQFDDYIMREFKVTNT----------KESASRVVRQYQFTAWPD-IGSPDSGGGLIDLIGQVQRWQQKC----GVQLTAVHCSAGVGRTGV
...||... ||. . .|.||.| . . |.|...|.| |. | | .||.|. .|. |..| . . |..| |..|.||
eifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGasRsGv
FCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
..|. . .| .. | ||||. ||.||..|| .|...|.| ..|..| |..
ylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlleav
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 313-569 | 3.7e-65 | 214.6 | In-house | 1-265 (270) | alignment | ||
Range on Protein: 313-569
Range on HMM: 1-265/270.0
FQRLSRNKAPPSKFQsaNLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMS-KKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQE
|..|..... .|.. . .|. ||||..|| ||||| .. . ||||||. |. . ||..||...| | |. .|||||||. .|||...
fkeldkeetsesdlp..eaargkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgl
MESGKVKVHRYWPGKQPT----SIGNLVVEMLHDKQFDDYIMREFKVTnTKESASRVVrQYQFTAWPDIGSPDSGG------GLIDLIGQVQRWQQKCGV
.| |. | |||| .. . . |.. | |.... . ||... ... .| . |.| .....||| | | . . |. .. .|.|....
eEkgrkkCerYWpaepkekvkledgkikvlalseekeegyiltrlrle.ekgeerrlv.HfwyntWpdhgvpreedsslstdqllkmlravrrsekeldk
Q-LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
. . |||||||||||.. |. | .. |. . ||| . ...||..|.|.||. ||||| |... || .
aePllvHcsaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavveyae
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 16-292 | 2.6e-63 | 208.6 | In-house | 6-280 (283) | alignment | ||
Range on Protein: 16-292
Range on HMM: 6-280/283.0
NGELLFSQEYGAFRSPDTVTSHHSLNQaNRFKNRYNNITAFDHCRVLLQPIEGdptsDYINANYLD---GYRKQREYIAAQGPLPETCHDFWRMVWEQNS
|. || . . . || . .| .. |. |||...| . | || |.. ||||| .. |.....||.||.|| .| |||.||....
nnnklfrevlkrlsvpdldadiasade.nkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdeki
RVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVL-QYHYTAWPDHGVPNSVTSVLNFVRKSSaVNLTEDY
|||.|. | |||| ||||. ||..|| | . . ..|. . .. ..| .. ..| | . | . | . |...| . | .
taivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvis.lqteskk
GPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQ
||.|||||.|.|||.... . | .| ...|. |||.. | ..| || .|| ||| |.|.. || ||||.| | || .
gPivvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalcgdtqiaavdlqs
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 306-567 | 1.1e-61 | 203.2 | In-house | 28-291 (297) | alignment | ||
Range on Protein: 306-567
Range on HMM: 28-291/297.0
QTEMDAEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYI-DGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCT
.. ...|.. | . .| || . |. . | .|||...|||||..||.|. .| .| |||||| | | . |.||||.|...|. |||.|.||| ..
kdrlekewealcayeaepstkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvv
IVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQ-FDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQl
||.|.. |.| ...|||| . . |... .. |||..| | . | . | .| | |. | .||. | | | |... .|.. .
ivnltrleeegvkqckrywpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrscp.
TAVHCSAGVGRTGVFCAVSILIERLKA-EAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
||||.|.|||||.... ....||. .|. |.. ||.||| .|.||.|.||..... |
ivvhcsdGaGrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavaee
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 305-574 | 2.9e-61 | 201.8 | In-house | 13-299 (301) | alignment | ||
Range on Protein: 305-574
Range on HMM: 13-299/301.0
GQTEMDAEFQRLSRNKAPPSKFQSANlpVNKHKNRYANVLPYDDTRVRLTMQAV--TEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDC
..........|.... ... . . ||. ||. |. .||| |. |. . . .||||.||||| .||.|||.|.|. |. ||||.||..
hsnkfeeqykelkegedksctvglse..enkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekp
CTIVMLSQEMESGKVKVHRYWPG--KQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTK---------------ESASRVVRQYQFTAWPDIGSPDSGGGL
.|||. .. |. | | ..||| .. .. |.. |.. ... . |...|...|. .. . .|. | |.| | ||. |
vsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtv
IDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPY
. | .| ||| | ||||..|.|.||.|.||| .| ||| ||||| .| .| ..| .|.| ||| . |. . .||. . |
LqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 307-569 | 1.3e-60 | 199.9 | In-house | 23-297 (300) | alignment | ||
Range on Protein: 307-569
Range on HMM: 23-297/300.0
TEMDAEFQRLSRNKApPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTeGSDYINANYIDGYMS--KKAFIATQAPIPDTIPDFWRMIWEQDCCT
... .|..|...... .....|.||.|..|||. .||||.|.||.|. . . ..|||| | .. .. .|..|.|.. |. |||.|.|||.
gkvfteyeripkkre.dallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvql
IVMLSQEMESGKVKVHRYWPGK----QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCG
|||| .| |.|| | ..|.| . . |. | .. | .| . .|. . | | |.| ||| | |. | .. . .|| ..|
ivmlteeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktn
VQL--------TAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLH
. |||||||||||| . .||. |. . .|. .....||||| .||| ||.| |..| .||.
seveskeskPPvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylk
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 32-278 | 2.1e-60 | 199.3 | In-house | 38-296 (300) | alignment | ||
Range on Protein: 32-278
Range on HMM: 38-296/300.0
DTVTShHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDpTSDYINANYLDG--YRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKC
|...| . .. | |||.... ....|| |.| . . ...|||| . |.|.||.|||||. |..|||.|||||. ..|||.|. || |. |.
dalls.taklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgkeks
HQYWPSSGSQ----NYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNL--------TEDYGPMVVH
..|.|...|. ..| .| . . . .. ... .| | ||| |. || |||||||. |.. |..... .| .| |..||
fkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskPPvlvh
CSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
||||||||| .. | .. .. . ..|. . . .|| || |.|| || ...||.. .
CsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikyl
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 34-275 | 9.6e-60 | 196.8 | In-house | 46-289 (297) | alignment | ||
Range on Protein: 34-275
Range on HMM: 46-289/297.0
VTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANY-LDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQY
|.. . .. | |||.... ..|| || |. . .|||||| || .. |||.||||..| |||.||||| . |||..|. || | .|..|
stkevakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildhdprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckry
WPSSGSQNYGVIHVNMMST-VELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTeDYGPMVVHCSAGVGRTGTYVVI
|| ||. |.. |...| . || .||| .| . | | | |.|. .||..||| | |.|.| || |.|||||.|.||||.|..|
wpdeGsevyhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrG.rscpivvhcsdGaGrtGvyili
DAQLKRIQAE-ATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLL
| |.|.. .|. . || ||. .|. .||. .. ..
dlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltava
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 2-316 | 3.7e-59 | 195.1 | In-house | 5-274 (392) | alignment | ||
Range on Protein: 2-316
Range on HMM: 5-274/392.0
PVDEFEEHVRRLHanGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCH
|| .| | . . ||..|. . .|| . .. | ||||.|| .| || |. |. | |||.|| |.... .. |||.||| . . .
pvaqfpafveknr..hsalffeefhdlpgpdiypqtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaasld
DFWRMVWEQNSRVIVMVTNCEERGrikchqywpssgsqnygvihvnmmstvelsdytirsfgvkrsGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRK
||||||...| |.|||. .| . | | |.|.| |||..||. ..|.|.|...
dfwrmvfqenvttiamvtklkegd..........................................kgddartvaqfhftewPdkdvpkhtssllkfike
SSAVnLtEDYG-PMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRP
.| .| |...|||||||||| . ||. . . . |||.|.| .| .| |||...|| .|. .|| . .| | . .....|
vkad.f.Gqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavledllwrntlipvvhftdhlqdlsts
STDTGQTEMDAEFQRL
| ... . ||. |
sdGdvrskqlkefrsl
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 7-284 | 5.8e-59 | 194.2 | In-house | 6-299 (301) | alignment | ||
Range on Protein: 7-284
Range on HMM: 6-299/301.0
EEHVRRLHANGellFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEG--DPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFW
..|| |.|. |...| . .. . ... .|...|. ||..||| .|. |..|.| . . .||||.|.|||......||||||. .| |||
gthvaakhsnk...feeqykelkegedksctvglseenkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfW
RMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS--QNYGVIHVNMMSTVELSDYTIRSFGVKRS-GSP--------------EERMVLQYHYTAWPDHG
|..|.. |||||| .|. . ||.||||.| ...| ..| .... . |..||.. || || . . |||.. | ||..|
rliwqekpvsivmvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdG
VPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTE
| ||. . . . . ||.|||||..|.|.|.|. .. | .|| |||.. . .| .. .|. .||. |.||. . ... .|.
vvreprtvLqviddvihrqqkigggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmylqlnsty
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 329-561 | 6.1e-59 | 194.1 | In-house | 3-234 (239) | alignment | ||
Range on Protein: 329-561
Range on HMM: 3-234/239.0
ANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYM-SKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQ
|. ||| ||||||.. || .|| | . ||||||.|. | | ||.|||| . . |||||.|.. | ||||. .| | |.|.|||
akkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst
pTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRwQQKCGVQLTAVHCSAGVGRTGVFCAVSILIER
. || | . . . | |||.| | ... .. | | ||.|| ||| | |. .. | .. . . | . .|||||||||| | . .. .
.skycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrq
LKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCY
| . ||.|. || .||.|| |||| ||| | .
akkqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 331-561 | 7.5e-59 | 193.8 | In-house | 4-233 (239) | alignment | ||
Range on Protein: 331-561
Range on HMM: 4-233/239.0
LPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYM-SKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQpT
||| ||||||.. || .|| | . ||||||.|. | | ||.|||| . . |||||.|.. | ||||. .| | |.|.||| .
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst.s
SIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRwQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLK
|| | . . . | |||.| | ... .. | | ||.|| ||| | |. .. | .. . . | . .|||||||||| | . .. . |
kycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitk.dslpgarpwvihcsagvgrtgaflvidamlrqak
AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCY
. ||.|. || .||.|| |||| ||| | .
kqktvdifnyvkairedrphmvqtseqyvfih
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 319-564 | 7.6e-58 | 190.5 | In-house | 17-267 (290) | alignment | ||
Range on Protein: 319-564
Range on HMM: 17-267/290.0
NKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVtegsDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVK
..| . ..|.|| |. .||| .| ||| .|..| . . |||||. .. |. .| || |.|.|. ||.|.|||.. ..||| . .| ...|
keasdfptreaklpenrnlnryrdvspydhsrikleradn....dyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqik
VHRYWPGKQP---TSIG--NLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQ-KCGVQLTAVHCSAGV
..||| .. . .| |.... .. . |..| ....| | .|.. .. .|.||| | |.| . ..... .|.. . | . .|||||.
caqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcsaGi
GRTGVFCAVS---ILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
||.| || | .|||. . . ||. ... .||..| ..||..| .| |...
GrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylai
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 334-564 | 8e-58 | 190.5 | In-house | 3-235 (237) | alignment | ||
Range on Protein: 334-564
Range on HMM: 3-235/237.0
NKHKNRYANVLPYDDTRVRLtmQAVTEGSDYINANYIDGYM-SKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPG-KQPTSI
|| ||||.|. || .|| | . |||||||.|..|. . | .||.| |. . |||.|.|.. | ||||. .|. ..| |.||| .||..
nkiknrygnivaydhsrvvl..kgagsgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GNLVVEMLHDKQFDDYIMREFKVTNTK-ESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQ-RWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLK
| | | . ....| || .| . ... |.. |||||.||| | |. |. . .. | . .||||||||||.| . .. . |
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvgrtgiflvidamlrqak
AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
. .||... |. . |.|| ..|||.|| | .||.
ekkvvdiynyvysieedrpyiiqtkdqyvfihqti
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 307-562 | 2.7e-57 | 188.8 | In-house | 6-260 (283) | alignment | ||
Range on Protein: 307-562
Range on HMM: 6-260/283.0
TEMDAEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVtegsDYINANYID---GYMSKKAFIATQAPIPDTIPDFWRMIWEQDCC
..... ...| | |. . . | ||.|||. ...|.| ||.| .. ||||| .| | .| .|..|.|. .|. |||.|..... .
nnnklfrevlkrlsvpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekit
TIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKE-SASRVVRQYQFTAWPDIGSPDSGGGL--IDLIGQVQRWQQKCG
.||||.. .| ..| .||| . |.. | . .. . .|..|. . . .. .. ||. | ..| | .... |. ..|
aivmltklqedlrikCsqyWPkrGsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvislqteskkgP
VqltAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQ
. ||||.|.|||.||.|.| .. ...|..||||..|| .||||. .|||..|| . ..
i...vvhCstgiGrtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhe
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 333-566 | 5.2e-57 | 188.2 | In-house | 47-277 (439) | alignment | ||
Range on Protein: 333-566
Range on HMM: 47-277/439.0
VNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKvkvhrYWPGKQPTSIG
.. |||| .| ..| ||| | | |||||||.|| .| .||||.| .| ||||...|. . |||||.. .|| | ||| .. . |
ydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlvesyk.....ywpsdaevcyg
NLVVEMLHDKQFDDYIMREFKVTNTKESA--SRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKA
...| . .. .. .|..| ||| | .... | | |....|||| | ..|.. .. ..| . ||||||||||| |. | .|.||.
diavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeeygpvvvhcsagvGrtGtiialdialeqlkl
EAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGE
| ||. || ||.|| |||. || | |... |
enkvdikgivkvlrkqrkqmvqalcqyvfiynavle
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 35-277 | 8.9e-57 | 187.1 | In-house | 32-279 (288) | alignment | ||
Range on Protein: 35-277
Range on HMM: 32-279/288.0
TSHHSLNQA--NRFKNRYNNITAFDHCRVLLQpiegDPTSDYINANYLDGYRK-QREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQ
. ..|. | . |||...| .|| || |. . . ||||| .. . ..||.|.||..| |||.||.|| |.||||... ||.|. |...
arkrsiaiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcPdfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkpkvdr
YWPSSG--SQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSA---VNLTEDYGPMVVHCSAGVGRTG
|||.. ....| ..| . |. |.. . | . .. .. . ..| ..|.||..|||.| ..|.|. . . . . |.||||||||||||
YwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaGvgRtg
TYVVIDAQLKRIQAEAT-VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEA
.. .. | .. .... .|. . | || || ||| ..|. .. |||
vfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavlea
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 70-293 | 1.3e-55 | 184.2 | In-house | 2-239 (272) | alignment | ||
Range on Protein: 70-293
Range on HMM: 2-239/272.0
PTSDYINANYLDGYRK---QREYIAAQGPLPETCHDFWRMvWEQNSRVIVMVTNCEERGRIKCHQYWP------------SSGSQNYGVIHVNMMSTVEL
|.|.||||....|| . . .....|||| |..||||. .|.. ..||.....||||| ||..||| | . .|| ..| ..|.. |
plsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseell
SDYTIRSFGVKRS-GSPEERMVLQYHYTAWPDHGVP-NSVTSVLNFVRKssavnltedYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVD-------
.||..| . ... . | |.|...|||.||||||| ... ..|..... ||..||||||..||||.|... | .. .|. ||
ldyilrellltlllsagearevmhlhytdwpdhgvpqeallellellld.........ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnl
-VYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAiACGDTEIQARDLRQR
....| .|| || .|| |.||. ....|||. ... ....|. |..
yleeaveelraqrpgavqteeqylflyeallel.lrsllsvraeyllaa
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 38-274 | 1.8e-54 | 179.5 | In-house | 32-273 (287) | alignment | ||
Range on Protein: 38-274
Range on HMM: 32-273/287.0
HSLNQANRFKNRYNNITAFDHCRVLLQpIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSG
. . |. |||| .. .|. |||| ||. ||||||||. .|... ..||||||.. | ||||.|.|..| .....| | .| ||..|||
aaeelaavkknryadvlPiddtrvlls.aegelGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPere
S-QNYGVIHVNMMS-TVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKS----SAVNLTEDYGPMVVHCSAGVGRTGTYVVI
| | ... .. .|..|.. . . | |.| |... .|||.... . ... || . . ... ||.|||...|.||.|... .
vPmrvGGysvvlldydikePeygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGiGrsGillat
DAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVL
. ..| . ||| . |. || .|. .|| |. |. . |
lvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyeal
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 44-283 | 1.8e-53 | 176.2 | In-house | 1-176 (182) | alignment | ||
Range on Protein: 44-283
Range on HMM: 1-176/182.0
NRFKNRYNNITAFDHCRvllqpiegdpTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTnceergrikCHQYWPssgsqnygv
|. |||| .| .|| | .||||||...|.......||.||||..|. ||.||..|.. ..||..| ...|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
ihvnmmstvelsdytirsfgvkrsgSPEERMVLQYHYTAWPDHGVPNsVTSVLNFVRKSSAvnlteDYGPMVVHCSAGVGRTGTYVVIDAQLKRiqaeaT
. .||...||.|. |||||||. . ..|.|... . . || .||||||||||||.|... .|.
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl.....g
VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDT
|.... | ..| .|. ||. ..||......||| . ...|
vsleeavklvrsrRpgmvitpnqyfflqlallellllkkt
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 361-570 | 2.5e-53 | 176.8 | In-house | 3-227 (272) | alignment | ||
Range on Protein: 361-570
Range on HMM: 3-227/272.0
GSDYINANYIDGYMS---KKAFIATQAPIPDTIPDFWRMiWEQDCCTIVMLSQEMESGKVKVHRYWP------------GKQPTSIGNLVVEMLHDKQFD
|.||||....|| . .........| | |. ||||. .|... |||.| .|.| |..|..|||| . .. ..|.|.| .|. ....
lsgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseelll
DYIMREFKVTNT-KESASRVVRQYQFTAWPDIGSPDSGggLIDLIGQVQRwqqkcgVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVD--------V
|||.||. .|.. . ...| |.....|.||| | |.. |..|. .... . ||||||..|||...|. .|.... .|..|| .
dyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld......ggpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyl
FQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHS
...|..||.|||..||| |||.|.|. | |.| |
eeaveelraqrpgavqteeqylflyeallellrs
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 326-566 | 3.2e-52 | 172.2 | In-house | 37-234 (392) | alignment | ||
Range on Protein: 326-566
Range on HMM: 37-234/392.0
FQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGkvkvhrywpg
..|. ..|..|||| |.|||| .||.| . . |||.|| ||... ..||.||.|.| . .. |||||..... .||.|... |
qtvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd..........
kqptsignlvvemlhdkqfddyimrefkvtntKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLtAVHCSAGVGRTGVFCAVSILI
| | | |..|| ||| . | |. .| .|. . | .||||||||||| .. ..
................................kgddartvaqfhftewPdkdvpkhtssllkfikevkadfGqythpl.iihcsagvgrtgvvisidsvv
ERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGE
. | |||||. | ..|..|| |||||||| | | .. |
ahakktrmvdvfnfvtnirrkrpymvqtkeqyafiygavle
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 306-567 | 2.3e-51 | 169.4 | In-house | 5-258 (267) | alignment | ||
Range on Protein: 306-567
Range on HMM: 5-258/267.0
QTEMDAEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTmqavTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTI
..|.. ||. . . |. |. .||. ..|||||||| | |. .|||| |..|| |.|||.|| |. || ||. .| .|.. .|
eceiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilr....tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvi
VMLsqeMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVrQYQFTAWpDIGSpDSGGGLIDLIGQVQRWQQKCGVQL
|.| . ... .....|| | | .|.|| .|. .|| . ... .||| |. | . | .| . . | |.| . . | . | .
vll...tkvftdnirlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahnvt.lyyykkw.nint.nnkpylkplfgilaknqlengnrP
TAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
|.||.||||.| | . .||.| | ..|.|. ....|.||...|.|||.| .....| ||
lvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 361-562 | 3e-51 | 168.8 | In-house | 1-164 (174) | alignment | ||
Range on Protein: 361-562
Range on HMM: 1-164/174.0
GSDYINANYIDGYMSKKAFIATQAPIPdtipdFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGkqptsignlvvemlhdkqfddyimrefkvtnTKES
|||||||...|... . .||.|.| . ||.|..|... |.||| .|.| |..|...||| ..|.
gsdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lred
ASRVVRQYQFTAWPDIGSPDSGGgLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKaEAMVDVFQTVKQLREQRPAMVQTKEQYEFC
.| . ||... ||| | ||. |.... .|........ ..|||||||||||...| ... .|. | .||....|..|| ||| |||| .||.|.
lerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfl
YQ
|.
yy
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 29-276 | 4e-51 | 168.9 | In-house | 28-275 (307) | alignment | ||
Range on Protein: 29-276
Range on HMM: 28-275/307.0
RSPDTVTSHHslNQANRFKNRYNNITAFDHCRVLLQpIEGDpTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIK
..|..|| . .|| ||||... . |..|.... ..| .|||| |||| | . .|.||||| .| ..|| |. ... ..|. .. | ..||
ktpegvtvea..fsantdknryqdvkcqdkgrivvk.fdgl.asdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakik
CHQYWPSSGSQNYG------VIHVNMMSTVELS--DYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVrksSAVNltEDYGPMVVHCSA
|.|||| |. | |. . . .|. . | .| . . | . .. .. |||.|||. . .|.. .||. | |.||||||
ceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainll...eavr..ydtnpvvvhcsa
GVGRTGTYVVIDA-QLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
||||.|| | | | | |. . |. . | || ||. .| | ||. .| ||||
GvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlle
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 311-571 | 5.6e-51 | 169.5 | In-house | 23-283 (314) | alignment | ||
Range on Protein: 311-571
Range on HMM: 23-283/314.0
AEFQRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDdTRVRLTMQAVTeGSDYINANYIDGYmskKAFIATQAPIPDTIPDF----------WRMI--W
... |.| . |. . |.|..|..|||| ..||.| .||.| . | |||||||.|.||. ..|||||.| . |. || |||. .
lvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvilpglpvs.gsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrg
EQDCCTIVM---------------------LSQEMESGkvkvhrywPGKQPTSIGNLVvemlhdkqfddyimrefKVTNTKESASRVVRQYQFTAWPDiG
.... .||| | . .. | . . . .| .... .| .| . .| . .|| |
dlnvrdivmsrdevladelsrLdaAlgKtpllildgng........neptaadlellk.................eelydpelferlgikylripvpD.g
SPDSGGGLIDLIGQVQRWqqkCGVQLTAVHCSAGVGRTGVFCAVSILIERLKaeamVDVFQTVKQLREQRP-----AMVQTKEQYEFCYQTLGEYLHSF
|... . ... .... ..|||.||.||||.|... .|. .|. |.. ......|..|| .... |||||... | ||| .
saplledfdeflefieea...dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleqyefilealleylkfl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 72-272 | 1.4e-50 | 166.7 | In-house | 2-164 (174) | alignment | ||
Range on Protein: 72-272
Range on HMM: 2-164/174.0
SDYINANYLDGYRKQREYIAAQGPLPetchdFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSsgsqnygvihvnmmstvelsdytirsfgvkrSGSPE
||||||..||... ...|| ||||. ||.|..|......||.....|.|. ||..|||. . .
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe...............................lredl
ERMVLQYHYTAWPDHGVPNSVTsVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQaEATVDVYNYVMMLRGQRNLMVQVEDQYVLIH
||...||.|. |||||||.. . .|.||. . . . ||..|||||||||||| |... |... | .||....| .|| || ||| ..|| ..
erlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrfly
D
.
y
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 334-568 | 4.8e-50 | 165.0 | In-house | 1-171 (182) | alignment | ||
Range on Protein: 334-568
Range on HMM: 1-171/182.0
NKHKNRYANVLPYDDTRvrltmqavteGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSqemesgkvkVHRYWPgkqptsign
|..|||| ..|||| .| ..||||||...|.. . |||||.| ..|..||.||..|... |||.|. ..|||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
lvvemlhdkqfddyimrefkvtntkESASRVVRQYQFTAWPDIGSPDsGGGLIDLIGQVQRwqqkcGVQLTAVHCSAGVGRTGVFCAVSILIERlkaeaM
| | . ||... ||| | || |.|.| .|.. ..|||||||||||...| .....
.........................ellerlgiqylylpwpDhgvpd.ldelldfieevle.....eggpvlVHCsaGvgRtgtlvaaylmkkl.....g
VDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
|.....||..|..|| ||.| .|| |... | |.|
vsleeavklvrsrRpgmvitpnqyfflqlallell
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 312-529 | 6.3e-47 | 155.2 | In-house | 26-257 (418) | alignment | ||
Range on Protein: 312-529
Range on HMM: 26-257/418.0
EFqRLSRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSkKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQE
|| || . ||. . | ||||.|.|| . |||.| ||||||||||||| | ||.|| |.|.|| |||||.||. | |||||.|
ef.rlleesvgpsetsegdkkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgayp.kqfictqgplpntiadfwrmvwenrcriivmlsre
MESGKVKVHRYWP----GKQPTSIG-------NLVVEMLHDKQF--DDYIMREFKVtnTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQK
| ..|. |||| |.| . | ||.. | . | |. .. | | .| . |||. ||| || . .|. . |..
sencrikcdrywpeqiggeqfsiygngnevfgtysvelveviqdpereiitrnirl..tfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnq
CGV-----QLTAVHCSAGVGRTGVFCAVSILIERLK
||||||||||| ||. |....|
iipssdrnvpiivhcsagvgrtgtfctavimmkkld
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 352-568 | 4.4e-46 | 152.1 | In-house | 2-173 (176) | alignment | ||
Range on Protein: 352-568
Range on HMM: 2-173/176.0
RLTMQAVTEGSDYINANYIDGYMskkaFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIgnlvvemlhdkqfddyimre
||.. ...||||||.|.|.. .||||.|.|.|..||..|..|... ..|.| .|.| |..|...||| . .|
rlrllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi....................
fkvtntkesasrvvrQYQFTAWPDIGSPDSgGGLIDLIGQVQRWQQKCgvQLTAVHCSAGVGRTGVFCAVSilieRLKAEAMVDVFQTVKQLREQRP-AM
||... ||| | ||. |..|. ........ . ..||||||.||||...| |. | ..|.......||||| .
...............qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplga
VQTKEQYEFCYQTLGEYL
||| |||.|.|. . ..|
vqtpeQyrflyefellll
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 69-271 | 8.4e-46 | 151.2 | In-house | 2-154 (172) | alignment | ||
Range on Protein: 69-271
Range on HMM: 2-154/172.0
DPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCeergrikchqywpssgsqnygvihvnmmstvelsdytirsfgvKRSG
|. ||||||.|||.|.. ...|| ||||..|..|||||..|.. ..||..|.. .
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydp
SPEERMVLQYHYTAWPDHGVPnSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLkriqaeATVDVYNYVMMLRGQRNLMVQVEDQYV
...||...||.|. ||||||| . .|.|.. . . .. ||..|||||||||||| |... | ..... | ..| .|. .|| ..||
ellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyr
LIH
...
fly
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 360-562 | 2e-45 | 149.9 | In-house | 3-155 (172) | alignment | ||
Range on Protein: 360-562
Range on HMM: 3-155/172.0
EGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEmesgkvkvhrywpgkqptsignlvvemlhdkqfddyimrefkvTNTKE
||||||||.|.|.| . |||||.| . |..|||||..|... .||.| .. ....|
egsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel...........................................lydpe
SASRVVRQYQFTAWPDIGSPdSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIerlkaeAMVDVFQTVKQLREQRPAMVQTKEQYEF
.| . ||... ||| | | . |.... ......... ..|||||||||||...| ... ......|...||.|| .||...|| |
llerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqyrf
CYQ
.|.
lyy
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 42-279 | 3.9e-45 | 150.3 | In-house | 44-281 (314) | alignment | ||
Range on Protein: 42-279
Range on HMM: 44-281/314.0
QANRFKNRYNNITAFDhCRVLLqPIEGDPTSDYINANYLDGYrkqREYIAAQGPLPETCHDF----------WRMV--WEQNSRVIVM------------
.|| |||| .| .| .|| | | .. .||||||.|.||. . .||.||||..|..|| |||| ...|.|.|||
flnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrdevladelsr
---------VTNCEERGrikchqywP---SSGSQNYGvihvnmmstvelsdytirsfGVKRSGSPEERMVLQYHYTAWPDHGVPnSVTSVLNFVRKSSAV
... ..| . . ... .. ... ||....|... .||...| . .. |.. ..
LdaAlgKtpllildgng........neptaadlellk....................eelydpelferlgikylripvpDgsap.lledfdeflefieea
nltEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAeATVDVYNYVMMLRGqRN---LMVQVEDQYVLIHDVLLEAIA
.. || .|||.||.|||||.||.. .|. . .....|.. | | ... .||. |...|||..
...dkggpvlvHCkaGkgRtgtfvvaaylmkllgv.sleealedvrlkRp.inpnpgfieqleqyefilealleylk
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 63-276 | 4.8e-45 | 148.7 | In-house | 3-171 (176) | alignment | ||
Range on Protein: 63-276
Range on HMM: 3-171/176.0
LQPIEGDPTSDYINANYLDGYRkqreYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYgvihvnmmstvelsdytirsf
|... |. .||||||...|.| .|| |||||.|. ||..|..|.. ...|..|.. | ||.||..||| . ..
lrllgldldldyinanlilgsr....piatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.....................
gvkrsgspeermvlQYHYTAWPDHGVPNSvTSVLNFVRKSSAVNLTEdyGPMVVHCSAGVGRTGTYVVIDaqlkRIQAEATVDVYNYVMMLRGQRN-LMV
||... |||||||.. . .|.... . || .||||||.|||||.|... .. | ..|.. . ..| || .|
..............qylhlpwpDhgvpdl.elllellefirealkeg..gpvlVHCsaGigRtgtlvaay....llelekglsveealalvreqRplgav
QVEDQYVLIHDVLLE
| ..|| .....|.
qtpeQyrflyefell
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 30-277 | 5.2e-45 | 148.5 | In-house | 19-258 (267) | alignment | ||
Range on Protein: 30-277
Range on HMM: 19-258/267.0
SPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDptsdYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEErGRIkc
|... | |. . |. .||... .|. || |. | . |||| |..||.... .|. |.|| | ||. .. .|. |||..|. . . |
sdtsstisqsiaeknqernrlddnlpyddtrvilrtkeee....yinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkvft.dni..
HQYWPSS--GSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERmVLQYHYTAWPDHGVPNSVTSvlNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGT
...|| ...| . |. | || | .. .| | |.| | . .. . .| . |.||.||.||||.||
rlfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahn.vtlyyykkwnintnnkpylk..plfgilaknqlengnrPlvvacsdGvGrsGt
YVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEA
..|||.||.|.. | ..|...... .| || .|.. ..|. ||..| |
flvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellaey
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 43-276 | 1.3e-44 | 147.0 | In-house | 53-281 (290) | alignment | ||
Range on Protein: 43-276
Range on HMM: 53-281/290.0
ANR--FKNRYNNITAFDHCRVLLQpiEGDPtSDYINANYLDGYRKqrEYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQN
.| |||| ... | ||.|. .| . ||. |||..| . .| .||.| .| |.|||| ... .|||. . | |. ||.||.| .
kntefkknrykdvvcndktrvilk..dGyd.GdyvhanyvkGlka..mfiltqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGev
--YGVIHVNMM-STVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKssavnLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKR
.| | | .. . .. . . |. | | .. .. .|||. |..| ..| .| | . ||.|||||||.|||||.| |.. |.
ltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlri.....lrkasGpvvvhcsaGiGrtGtfvaievglqi
IQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
. .|. . | || | |||. ||... ..||.
lldGkeldlldlvralrnsrlnsvqvdiqylalveilld
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 41-237 | 3.7e-43 | 142.8 | In-house | 44-255 (418) | alignment | ||
Range on Protein: 41-237
Range on HMM: 44-255/418.0
NQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRkQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSS----
.. | |||| || .| || |. |. ||||||||.|| ...|..|||||.| ||||||||. |.|||.. | |||| .|||
kkhntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidgay.pkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqigge
-------GSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFV-----RKSSAVNLTEDYGPMVVHCSAGVGR
| . .| |... .. . | . .. . | | . ||.| |||| .|. . ... |. . .. |..|||||||||
qfsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgr
TGTYVVIDAQLKR
|||.. .|.
tgtfctavimmkk
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 300-568 | 4.6e-43 | 142.4 | In-house | 9-277 (307) | alignment | ||
Range on Protein: 300-568
Range on HMM: 9-277/307.0
PSTDTGQTEMDAEFQRLSRNKapPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTegSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWE
. | | ... ||. |.. . | . . | .|||| .| | .|. .... .. |||| |||. . | ||..| | .|. .|| |. .
rtldkgvqalvdefrvlakkt..pegvtveafsantdknryqdvkcqdkgrivvkfdgla..sdyihanylgiaikpkkficaqgplentqysfwamaiq
QDCCTIVMLSQEMESGKVKVHRYWPGKQPT-----------SIGNLVVEMLHdkqFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDL
.. ...|| . .| .|.|...||| .. |. || .. | |. .. .. . || ....|.. ||| | |. . |.|
ekvesvimlckvielakikceqywpleegqklvfgeapntisvanlgakkla...pdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainl
IGQVQRWQQKcgvqlTAVHCSAGVGRTGVFCAVSILIERL-KAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
. |. . |||||||||.| |.|.. ... . . |. . |..||.||. .||. || . .. | ||.
leavrydtnp.....vvvhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlleyf
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 79-272 | 2.3e-42 | 139.6 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 79-272
Range on HMM: 1-144/152.0
YLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWpssgsqnygvihvnmmstvelsdytirsfgvkrsgspeermvlQY
..|||....|.||.|||.|.|. |||||..|.. ..|||.|...|.|..||.||. ||
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qy
HYTAWPDHGVPNSVTSVLNFVRKSSAVnLTEDYGPMVVHCSAGVGRTGTYVVIDAQLkriqaeATVDVYNYVMMLRGQRNLMVQVEDQYVLIHD
... |||||||.. .| ... . .. || .||||||||||||.|... | |.....| ..| .|. .|. ..|. ....
lhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 34-276 | 3.1e-42 | 139.4 | In-house | 37-285 (305) | alignment | ||
Range on Protein: 34-276
Range on HMM: 37-285/305.0
VTSHHSLNQA-NRFKNRYNNITAFDHCRVLLqpiEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQY
. ... .| .. |||| .. .|. || | || .|| |||. . . .| .| || .|| ||| | .... | |. | |.| ||..|
fekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcley
WPSSGSQNY------GVIHVNMMSTVELS-----DYTIRSFGVKRSGSP-EERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNltedyGPMVVHCSA
..| . | | . |.|.|. . ... . |. . | | .||. ||| ||| . ...|... |. . ||.||||||
faskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekarpsk.....gpivvhcsa
GVGRTGTYVVIDAQLKRIQAEATVDVYNYV-MMLRGQRNLMVQVEDQYVLIHDVLLE
|.||||. |... |... | .. . . . .| ||| .| ..||...|.|.|.
gigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqviln
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 41-276 | 7.4e-42 | 137.9 | In-house | 33-267 (281) | alignment | ||
Range on Protein: 41-276
Range on HMM: 33-267/281.0
N-QANRFKNRYNNITAFDHCRVLLQP-IEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS
| | |||| || ..| || |. . ..||| |||. .| || .||| || |||||.|..|. |||. . | | || .|.|
nqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnah
--QNYGVIHVNM-MSTVELSDYTIRsfgVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNltedyGPMVVHCSAGVGRTGTYVVIDAQL
.. . |. |||. | | | .. | | |.. .. . ||| ||.| .|. .|| | | |.||||||||.|| . .. |
cclqfdklsvsyedstvnkslvttr...lnlsyegetrlithwlwkewpdwqvpessevmlkilrkirars.....tppvihcsagvgrsgtlmaveial
KRIQAEATV-DVYNYVMMLRG-QRNLMVQVEDQYVLIHDVLLE
. |.. |. |. . | || | || .||.|| |||.
qsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 369-562 | 2.7e-40 | 132.9 | In-house | 1-144 (152) | alignment | ||
Range on Protein: 369-562
Range on HMM: 1-144/152.0
YIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWpgkqptsignlvvemlhdkqfddyimrefkvtntkesasrvvrQY
.||||. ...|||||.| | |..|||||..|... ||||| ...| ||.|...|. ||
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi...........................................qy
QFTAWPDIGSPDSGGGLIDLIGQVQRWqQKCGVQLTAVHCSAGVGRTGVFCAVSILIerlkaeAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQ
... ||| | ||. |..|. .... .. ..|||||||||||...| ... |.....|...||.|| .|....|..|.|.
lhlpwpDhgvpdlsqlllflllfiekl.aldkggpvlVHCsaGvgRtgtlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 308-567 | 9e-40 | 131.1 | In-house | 28-282 (290) | alignment | ||
Range on Protein: 308-567
Range on HMM: 28-282/290.0
EMDAEFQRLSRNKAPPSKFQSANLPVNK--HKNRYANVLPYDDTRVRLTMqaVTEGsDYINANYIDGYmsKKAFIATQAPIPDTIPDFWRMIWEQDCCTI
|. |. . | .. . | .|||| .| | ||| | .| ||. |||..| | || || .. ||. |.|||. ... .|
elakeyleklkpylpvqylerkifdkntefkknrykdvvcndktrvilkd..GydG.dyvhanyvkGl..kamfiltqGalkdtvidiwrmvlqekvaai
VMLSQEMESGKVKVHRYWPGKQPT--SIGNLVVEMLHDKQFDDY-IMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRwqqKCGVq
||| . .| || | ..|.| |. ..|.. | ... |. |.. . | . .. . ... .. .||| . | |. .. ... |
vmlceliedGkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrk...asGp.
lTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
.||||||.|||| | |. . .. | .|. ..|. ||. | . || || . | ..
.vvvhcsaGiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 35-276 | 3.9e-39 | 129.1 | In-house | 43-287 (305) | alignment | ||
Range on Protein: 35-276
Range on HMM: 43-287/305.0
TSHHSLNQ---ANRFKNRYNNITAFDHCRVLLQpieGDPTSDYINANYLDGY-RKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCH
|| . ||||... . |. |.|. . |||| |||. .. .|.||||| .| .|| || ... |||. . | |..||
qvafnanqsadiaitknryqdvpcqdqsavkld...kpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkca
QYWPSSGSQN----YGVIHVNMMSTVEL-SDYTIRSFGVKRSGSPEERM-VLQYHYTAWPDHGVPNSVTSVLNFVrksSAVNltEDYGPMVVHCSAGVGR
|||| . .. |.. |. . . | |. .. . | ...| | . ..| ||| ||| . |... ||. |.|||||||.||
qywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslell...sair..gskvpivvhcsagigr
TGTYVVIDAQLKRIQAEAT-VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLE
||| | |. |..| . . . | || || .| . ||. || |.|.
tgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmln
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 311-566 | 5.2e-38 | 125.3 | In-house | 15-267 (281) | alignment | ||
Range on Protein: 311-566
Range on HMM: 15-267/281.0
AEFQRLSrnKAPPSKFQ-SANLPVNKHKNRYANVLPYDDTRVRLTM-QAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVML
|| | ||| . | |||..||||.|. | .||.| . . .||| |||| . |. .| || | .| |||||||... .||||
qefsnlp..gdppsdlctvfnqpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivml
SQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQqkcgvQLTAVHC
| .|. . |. |.| . . . . .. . . .. . | .|.. .. . ||| |.| .. .. ... .||
cqfletnrekcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkirars.....tppvihc
SAGVGRTGVFCAVSILIERLKAE-AMVDVFQTVKQLRE-QRPAMVQTKEQYEFCYQTLGE
||||||.| . || | .. ... .. |. | | .|| | | ||| .|| . .. | .
sagvgrsgtlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlld
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 345-564 | 2.5e-37 | 123.6 | In-house | 1-167 (178) | alignment | ||
Range on Protein: 345-564
Range on HMM: 1-167/178.0
PYDDTRVRLTMQAVTEGSDYINANYIDGYmskkaFIATQAPIpdtiPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPtsignlvvemlhdkqf
|.|.||| |.. .|.||||||..|... ......| .|......|... .||.|..|.| |..| ..||| .
pldrtrvllsnleglersdyinaseilpg.....lylgslpp....addlellkelgithivnlteelelgflkcdpywpeeag................
ddyimrefkvtntkesasrvvRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGvQLTAVHCSAGVGRTGVFCAVSILIERlkaeaMVDVFQTVKQLR
||... .|| | ||. . ... ........| ..|||||||||.|...| ..... ..... ....|
.....................iqylhipipDhgvpdllehflefvefieealdekg.gpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvr
EQRPaMVQTKEQYEFCYQTL
|.|| .|.. .|....|.
erRp.ivpnpgqlrqLyefe
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 56-276 | 1.3e-36 | 121.3 | In-house | 2-169 (178) | alignment | ||
Range on Protein: 56-276
Range on HMM: 2-169/178.0
FDHCRVLLQPIEGDPTSDYINANYLDGYrkqrEYIAAQGPlpetcHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSqnygvihvnmmstvels
.|..||||...|| ..||||||.. ... |.....| |......|.. ..||..|. |.|..||..|||.. .
ldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag.................
dytirsfgvkrsgspeermvLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDyGPMVVHCSAGVGRTGTYVVIDAQLKRiqaeaTVDVYNYVMMLRG
.||... .||||||.. .|.||. .. ... || .|||||||||.|| |... .|. ..... . ..|
....................iqylhipipDhgvpdllehflefvefieealdekg.gpvlVHCsaGvgRsgtlvaaylmkkl.....glsleeaielvre
QRNlMVQVEDQYVLIHDVLLE
.|. .|. ..|. .... |.
rRp.ivpnpgqlrqLyefelr
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 301-568 | 1.9e-36 | 120.3 | In-house | 18-289 (305) | alignment | ||
Range on Protein: 301-568
Range on HMM: 18-289/305.0
STDTGQTEMDAEFQRLSRNKAPPS---KFQSAN-LPVNKHKNRYANVLPYDDTRVRLTMQAvteGSDYINANYIDGYM-SKKAFIATQAPIPDTIPDFWR
. | | . ||..|.. | |.. . ... ||||..| | . |.| . |||| |||. | .| ||..| |. .|| .||
aldvgvdklreefrglakytrpdmtqvafnanqsadiaitknryqdvpcqdqsavkldkps...psdyihanyvgcpmipekrficaqgpldqtidefww
MIWEQDCCTIVMLSQEMESGKVKVHRYWP---GKQPTSIGNLVVEMLHDK-QFDDYimREFKVTNTKE----SASRVVRQYQFTAWPDIGSPDSGGGLID
|. .. |||| . .| ||.|. .||| |.. . . .||| . .. | ..| . . . ||. |.| ||| | | ..
mviqnkveqivmlcktvelgklkcaqywpaaqgeklelksgivvenvsgskpmerd..aeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltsle
LIGQVQRWQqkcgVQLtAVHCSAGVGRTGVFCAVSILIERLKAEA-MVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
|. .. . | . ||||||.|||| |. ..|.. . . . || ||.|| .|. || | .. . .|.
llsairgsk....vpi.vvhcsagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmlnyf
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 333-558 | 4.8e-36 | 119.0 | In-house | 49-271 (301) | alignment | ||
Range on Protein: 333-558
Range on HMM: 49-271/301.0
VNKHKNRYANVlP-YDDTRVRLtmqaVTEGSD-YINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQP--
..|.|.|| .| | .| |.. ...| | ||.|. . |||||.|...| ||| |. | .||||.|..| . | . | | | .
lpkdkhryptv.PckPstavev....ivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisek
TSIGNLVVEMLHDKQF--DDYIMREFKVTN-TKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKcgvqlTAVHCSAGVGRTGVFCAVSILI
|| ... . .. .. . |...|.. |.. |.| | ||.. |.| | | | | ||. |.. .. ||||||.||. | . .|
ldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkksekP.....ivvhcsaGiGrsvafigteyla
ERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYE
...|. ... ...|.|||.| |||..|
reveadptieltealkhlrehrwngvqtnsqly
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 71-275 | 8.3e-36 | 118.2 | In-house | 2-150 (151) | alignment | ||
Range on Protein: 71-275
Range on HMM: 2-150/151.0
TSDYINANYLDGYrkqreYIAAQGPLPetchDFWRMVWEQNSRVIVMVTNCEERGriKCHQYWPSSGsqnygvihvnmmstvelsdytirsfgvkrsgsp
|||||..|..|. ... .|||. ||.....|.. ..||.... |||| .|..|.|. |
lsdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg.................................
eeRMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAvnltEDYGPMVVHCSAGVGRTGTYVVIDAQLKRiqaeatVDVYNYVMMLRGQRNLMVQVEDQYVLI
. ||..... |||.|.| | .||.|... . . ||..||||||.||||| |... | . |... . ..| .| .|| ..|....
..ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
HDVLL
. .||
lfall
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 308-481 | 1e-35 | 118.0 | In-house | 8-182 (297) | alignment | ||
Range on Protein: 308-481
Range on HMM: 8-182/297.0
EMDAEFQRLSRNKaPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTmqAVTEGSDYINANYIDGY--MSKKAFIATQAPIPDTIPDFWRMIWEQDCCTI
|..|| . | ... . .| ||. . .|||| ..| .|||||.| | ..|||||.|. .. .| .| |. .|. |||....||| .|
eleaekdllldea.rgesfssakrnsslrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvi
VMLSQEMESGKVKVHRYWPGKQ--PTSIGNLVVEMLHD--KQFDDYIMREFKVTNTkeSASRVVRQYQFTAWPDIGSPDS
||... | |. | ||| . |..||| | . .|| |. |... | ||||| || .||| | |
vmvaklqedGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyr..sesrvvrhvqflswpdhGvpsd
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 361-563 | 2.1e-35 | 116.9 | In-house | 2-148 (151) | alignment | ||
Range on Protein: 361-563
Range on HMM: 2-148/151.0
GSDYINANYIDGYmskkaFIATQAPipdtIPDFWRMIWEQDCCTIVMLSQEMESGkvKVHRYWPGKQptsignlvvemlhdkqfddyimrefkvtntkes
|||||..|..|. ......| .||.....|... |||.| .|.| | . ..|.| .
lsdyinfsyvtgg.....lyrsggp....ladflellkelgiktivnlrseeerg..ycpeylpelg.................................
asRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRwqqkCGVQLTAVHCSAGVGRTGVFCAVSILIERlkaeamVDVFQTVKQLREQRPAMVQTKEQYEFC
. |...... ||| | |.| ..... .... .. . ..||||||.||||...|. ..... |.........|..|| .||...|. |.
..ievlhipildwpdpglplsfdavleflellld....kkngpvlvHCsaGkgRTGtlvalylmllg......vsleealeeyrlkrpgvvqpnqqflfq
YQT
..
lfa
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 291-568 | 2.9e-35 | 116.5 | In-house | 6-287 (305) | alignment | ||
Range on Protein: 291-568
Range on HMM: 6-287/305.0
RQRIKELMRPSTDTGQTEMDAEFQRLSRNKApPSKFQSANLPVNKHKNRYANVLPYDDTRVRLtmqAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTI
...| .... . . | . . |||. . | . |... ...|||| .| |. ||.| . .|| |||. | || ||||. .|
kkqilkfvkrtlekgpaglraefvamkrfnd.fekmkafkeaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektc
PDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIG------NLVVEMLHDKQFDDYIMREFKVTNT------KESASRVVRQYQFTAWPDIGS
||| | ... .| || . .| | | . |.. |. . ..| . .... . |||.| . .| | .| . ||| |
adfwymclqdkveaifmlcnllekgakkcleyfaskdkdvlefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgv
PDSGGGLIDLIGQVQRwqQKCGvqlTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVF-QTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
| . ...|. . . | ..||||||.|||| . ....| | ... . ....|||| .|| .|| | .| . .|.
paadlailellekarp..skgp...ivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtdaqylfvhqvilnyf
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 43-287 | 3.7e-35 | 116.0 | In-house | 51-298 (310) | alignment | ||
Range on Protein: 43-287
Range on HMM: 51-298/310.0
ANRFKNRYNNITAFDHCRVLLQpIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS-QNY
. |||| .. | .|| |. |. ||| |||. . .| .|||| | |||||.... . |... . | || || |||| | . |
kymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtety
GVIHVNMMST----VELSDYTIR--SFGVKRSGSP---EERMVLQYHYTAWPDHGVPNSVTSVLNfVRKSSAVnlteDYGPMVVHCSAGVGRTGTYVVID
|.| | .| |. . .. | | .| | .. ||| |||. . | . | .|| |||||||..|... | ..
gcirvtnlsesseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtvp.qrllaqv....rhgpcvvhcsagkdrlyvvvalk
AQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLeAIACGDTEIQA
...... ||. . . |. .| .| | ||..|. | . ..| |.||.
lkidkldrglkvdaeevktellksraiciqtelqyliidrvri.ifargetevae
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 43-200 | 4.4e-35 | 116.0 | In-house | 32-191 (297) | alignment | ||
Range on Protein: 43-200
Range on HMM: 32-191/297.0
ANRFKNRYNNITAFDHCRVLLQpiEGDPTSDYINANYLDG--YRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSS--GS
. ||||..| |.| || |. . . .|||||.|. .. || ||||| .| .|||..|.||. ||||||.. .| || || ||||. .
sslrknryrdilatddtrvkll..rviterdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkcapywpsvvqer
QNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVR
.. | . |. .|.. .. .. |.|.| . .|||||||. . . |
lkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledlvrfqa
|
|||||||||
PTPc_DSPc_SM00012 | 465-564 | 6.8e-35 | 114.8 | In-house | 2-103 (105) | alignment | |||
Range on Protein: 465-564
Range on HMM: 2-103/105.0
VRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGV-QLTAVHCSAGVGRTGVFCAVSILIERLKAE-AMVDVFQTVKQLREQRPAMVQTKEQYEFCYQ
|..|..|.||| | |... ...|. .|.....|.. . . |||||||||||.|.|..||...|..| ||.||.||.||.||| ||||.||| |.|.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
TL
|
al
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 43-294 | 1.3e-34 | 114.5 | In-house | 42-286 (288) | alignment | ||
Range on Protein: 43-294
Range on HMM: 42-286/288.0
ANRFKNRYNNITAFDHCRVLLQpiegDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYG
|| ..||.|. | .|| |. | . ||.|| . . .| | || || | .|.|. |.. . |||... |.|. | .|.|| ..
anptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
VIHVNMMSTVELS--DYTIRSFGVKRSGSPEERM-VLQYHYTAWPDHGVPNSVTSVLNFVRKSsavnlTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQ
. .. . .. . | ... .. | ||.. | . |. |.|.|||.. | |... . |.|||.||||||||| ..| |. ..
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl.....kslqkPivvhssaGvGrtgtlililialeslr
AEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEiQARDLRQRI
. . . . . || .| .|.| ||. .| ..|| .. . . |... ..
lddflgirsllaklreerfkaiqtemqylyvhrcvleelllkkyk.vlredfvkl
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 34-198 | 4.5e-33 | 109.2 | In-house | 18-186 (319) | alignment | ||
Range on Protein: 34-198
Range on HMM: 18-186/319.0
VTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQ-REYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQY
... . . . |.|. |. . . || || | |. . |..|.|. ||.. ||||| .| .. ||||.||||.||||| .|. | | .| .|
iaradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaey
WPSS----GSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYtAWPDHGVPNSVTSVLNF
.|.. . . || | | . | | .. .|| | | . | | |.. .|| . ....
lPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliam
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 333-559 | 8.6e-33 | 108.2 | In-house | 51-281 (310) | alignment | ||
Range on Protein: 333-559
Range on HMM: 51-281/310.0
VNKHKNRYANVLPYDDTRVRLTMQAVTEgSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTS-I
. |||||..|. |..||.|... ||| |||. ...|| .| |. || ||||||... . .|..| . .| |. |. ||| |
kymhknrysdvvcldtsrvklkidksry.edyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtety
GNLVVEMLHDkQFDDYIMREFKVTNTKES------A----SRVVRQYQFTAWPDIGSPDSGGGLIdliGQVQRWQQKCGvqLTAVHCSAGVGRTGVFCAV
| . | | . ... . .. || . | .. ||| | || . | | . | ||||||..|..| .|.
gcirvtnlse.sseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdekchtv...pqrllaqvrhg..pcvvhcsagkdrlyvvval
SILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEF
. |..|. ||. . . .|. .| .||. || .
klkidkldrglkvdaeevktellksraiciqtelqyli
|
|||||||||
PTPc_DSPc_SM00012 | 175-276 | 2.6e-32 | 106.5 | In-house | 2-105 (105) | alignment | |||
Range on Protein: 175-276
Range on HMM: 2-105/105.0
VLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTED-YGPMVVHCSAGVGRTGTYVVIDAQLKRIQAE-ATVDVYNYVMMLRGQRNLMVQVEDQYVLIHD
| .||||.|||||||....|.|...|. .. .. .|.|||||||||||||.|..| |.....| .||....| .|| ||. ||| |.||. ...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
VLLE
.|||
alle
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 307-568 | 3.9e-32 | 106.4 | In-house | 19-271 (288) | alignment | ||
Range on Protein: 307-568
Range on HMM: 19-271/288.0
TEMDAEFQRlSRNKAPPSKFQsaNLPVNKHKNRYANVLPYDDTRVRLTmqavTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIV
.. |.. | |.|. . . | ..|| |. | |||.|. . ||.|| . |. .| .|||. || .|.|. |.| ||
eglkkeyrd.spneasidiid..sfianptrdryenlprcditrvkls....ddpdfyiaanvvssakykrrlicaqaPlngtieelWkmllesdveyiv
MLSQEMESGKVKVHRYWPGK--QPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRV-VRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQkCgvql
||.. .| || | |.| | . . || | . .... | ... . ..|| .| |.. . |.| | |.. . |. .. |.
mlcellekGkeksaeyfPsklGekarigrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevlkslqk.P....
TAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
||.|||||||| . . | .| |. . . . . ...|||.| .||. || . .. . |.|
ivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqylyvhrcvleel
|
|||||||||
subfamily_egg_pd | Subfamily egg | 32-275 | 1.6e-31 | 104.1 | In-house | 28-267 (307) | alignment | ||
Range on Protein: 32-275
Range on HMM: 28-267/307.0
DTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERgrIKCHQ
| .. ...... |. | | . . | .|| |. .| . |.| ||...| |.| || || .| .||||||.... . |||.| | .|.
deislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..ercey
YWPSSGSQNY----GVIHVNMMSTVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGvpnSVTSVLNFVRKSSAVNltEdygPMVVHCSAGVGRTGT
||| . |.. | .... . . .| | .| |. .| . |.. . . | | |. .|| . . |.||.. || ...|
ywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerflehwqgdvnnss...dvysplrvlrklrnls..k...pvvvqdilGvskaat
YVVIDAQLKRIQAEAT--VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLL
| |. | . . | . |..|| .|.| |. .|.... ..|
lvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvl
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 152-321 | 1.9e-31 | 103.9 | In-house | 72-237 (440) | alignment | ||
Range on Protein: 152-321
Range on HMM: 72-237/440.0
VELSDYTIRSFgvkRSGsPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVM
| ||| |. .| | | . |||| .|||.|||. . ||.... . . ||..||||||.|||| ...|. |. . .|.....
vpdsdyinasy...ing.iesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfin
MLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEIQARDLRQRIKELMRPSTDTGQTEMDAEFQRLSRNKA
.| .| |||. .||...|...||.. |||| | |. .|.... |. | .. .. ||. |...|
smrnnrpqmvqtpeqyafvheavlegllcgdtliledditerveqiqwpnphtdksplqqefegyskkna
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 73-267 | 1.6e-30 | 100.9 | In-house | 76-270 (301) | alignment | ||
Range on Protein: 73-267
Range on HMM: 76-270/301.0
DYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIH--V--NMMSTVELSDYTIRSFGVKRS-
| ||... . . .||.||||..|..||| |. . |||... |. ||..| |.. |.. . . . . .. . . |.. |. |
vPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekceeylpvkisekldigrfkikiknkelilnkkiskrtlevedst
GSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRkssAvnLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQY
| . | |. | |. |.|.|||.| . . ... . . |.|||||||.||. ... . ....|. |... . . || .| || . |
gkfatrtvthyqysewtdrgvPkshaelfdlme...l..vkksekPivvhcsaGiGrsvafigteylareveadptieltealkhlrehrwngvqtnsql
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 47-279 | 3.3e-30 | 99.9 | In-house | 46-277 (312) | alignment | ||
Range on Protein: 47-279
Range on HMM: 46-277/312.0
KNRYNNITAFDHCRVLLQpieGDPtSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPS-SGSQNYGVI-
||| || .| | | || || ||.. | ....|||| .|| ||... | |.... | | || .| | .
lnrypniqcwdrgrftla...gde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdledhr
-HVNMMSTVELS-----DYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLnfvRKSSAVNltEDYGPMVVHCSAGVGRTGTYVVIDAQLKRI
. .. . .|. | | . | . .| . .| ...|||||.|.|. . | | |||. | |.. ||||||||||| ..|.. . .
vyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtal...rllsavk..kdkkpviahcsagvgrtgtlaliesmiaal
QAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIA
. .| . ..|| .| |.| ||| ..|| .
rhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 332-493 | 4.2e-30 | 99.5 | In-house | 25-191 (319) | alignment | ||
Range on Protein: 332-493
Range on HMM: 25-191/319.0
PV-NKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMS-KKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQP-
|| | |.|..||.| .||| | .. . . |..|.|. || . . .||.|.. |. ||||..||| .|| |.. | | . .|.| |.
PvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcaeylPtketl
---TSIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFtAWPDIGSPDSGGGLIDLIGQVQ
. |.. | . . . | |.. . . . ... || . | . |.. . | . || .. .|.
dntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevr
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 331-568 | 6.3e-30 | 99.1 | In-house | 32-270 (285) | alignment | ||
Range on Protein: 331-568
Range on HMM: 32-270/285.0
LPVNKHKNRYANVLPYDDTRVRLTmqavTEGSDYINANYIDGY-MSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPT
| ||||.| ..||| | ||| |... . ..|.|| |.|.|. |||.||... . ..|| .| | |. |.| |
yeanpdlnryadvrcieetrvvlk....nhdrdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
S--IGNLVVEM--LHDKQFDDYIMREFKVTNTKESASRV--VRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgvQLTAVHCSAGVGRTGVFCAVSI
.|. . . ... |. . |.||....| . . | ||| .|. .|.| |.. . | . .|||||||||| | .
vvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpke..kpicvhcsagvgrtatfvgidy
LIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
|. . ..... |...| | ||.. |. | | | ||.
atirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 41-278 | 1.9e-29 | 97.5 | In-house | 32-270 (285) | alignment | ||
Range on Protein: 41-278
Range on HMM: 32-270/285.0
NQANRFKNRYNNITAFDHCRVLLQPIEgdptSDYINANYLDGY-RKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGS-
.|| ||| .. . . ||.|. . ||| |... . | ||..||||||| |||.|..... ..|. | | || |.|
yeanpdlnryadvrcieetrvvlknhd....rdyihaswmrmpgkdqstyittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklge
-QNYGVIHVNMMSTVE--LSDYTIRSFGVKRSGS--PEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDygPMVVHCSAGVGRTGTYVVIDA
..| . . | .. . .. | . | . . . |||. |. .... . || | |..|||||||||| |.| ||
vvkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpkek..picvhcsagvgrtatfvgidy
QLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
|| . ... . | .| | || |..... ||.| .
atirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 84-272 | 5.1e-27 | 89.3 | In-house | 2-198 (199) | alignment | ||
Range on Protein: 84-272
Range on HMM: 2-198/199.0
RKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPS--SGSQNYGVIHVNMMSTVELSDYTIRSFGVK--RSGSPEERMVLQYH
. || |||.| || || |||.|||| | |||| . . |||. ||. .|| . | . . .|||| .. . . | | . .|
kgqrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyq
YTAWPDHGVPNsVTSVLNFVRKSSAV---NLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAE--ATVDVYNYVMMLRGQRNLMVQVEDQYVLIHD
.|.| .. || |. . || | | | |..|||| | | || .| .| .. . . ||... || | .. ..| .|..
ftswkekttpn.valfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 85-272 | 6.7e-27 | 88.9 | In-house | 2-197 (198) | alignment | ||
Range on Protein: 85-272
Range on HMM: 2-197/198.0
KQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPS--SGSQNYGVIHVNMMSTVELSDYTIRSFGVK--RSGSPEERMVLQYHY
|| |||.| || || |||.|||| | |||| . . |||. ||. .|| . | . . .|||| .. . . | | . .| .
gqrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqf
TAWPDHGVPNsVTSVLNFVRKSSAV---NLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAE--ATVDVYNYVMMLRGQRNLMVQVEDQYVLIHD
|.| .. || |. . || | | | |..|||| | | || .| .| .. . . ||... || | .. ..| .|..
tswkekttpn.valfvgfvvasrevskkyeqekdapvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 46-168 | 1.5e-26 | 88.0 | In-house | 49-186 (350) | alignment | ||
Range on Protein: 46-168
Range on HMM: 49-186/350.0
FKNRYNNITAFDHCRVLLQ----PIE----GDPTSDYINANYLDGY----RKQR--EYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQ
||||.|| ..| || |. . . |.|||||||| . . |||.|.|||.| .||.... . . .||...|. | .. ||..
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPSSGSQNYGVIHVNM-MSTVELSDYTIRSFGVKRSG
||. . ... | .. .... | ...|..||.
YWqegsydditvklaskwenimgindsslysadvkkea
|
|||||||||
subfamily_egg_pd | Subfamily egg | 317-564 | 6.1e-25 | 82.5 | In-house | 23-266 (307) | alignment | ||
Range on Protein: 317-564
Range on HMM: 23-266/307.0
SRNKAPPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESgk
. . . .. | |..| | | | .||.| .. |.| ||...| || .|||. .| |||||...... ||||. ||
leesvdeislttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..
VKVHRYWPGKQ--PTSI--GNLVVEMLHDKQFDDYIMR--EFKVTNTkESASRVVRQYQFtAWPDIGSPDSGgglIdligQVQRWQQKCgVQLTAVHCSA
. . ||| . . . |.| .| |. .. | ..| ..|. . . | . .| . . | . .| | .. . . |..
erceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGg.ddeerflehwqg.dvnnssdvysp...l....rvlrklrnl.skpvvvqdil
GVGRTGVFCAVSILIERLKAEA--MVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
|| ..... |. | . | | ..|. || .|. |.. .| | |. .
GvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlv
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 436-566 | 2.3e-24 | 81.1 | In-house | 18-141 (145) | alignment | ||
Range on Protein: 436-566
Range on HMM: 18-141/145.0
VEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgvQLTAVHCSAGVGRTGVFCAVSILIErlkaeAMVD
. . . | | . . .|...| .| . ||... ||| | ||. |.... ........ ..|||||||||||...| .... |.
taldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlvaaylmll.....lgvs
VFQTVKQLREQRPAMVQTKEQYEFCYQTLGE
........|.||| .|.. .|..|.|. . |
leealelvrsqrpgavpnpgqlrflyefele
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 305-567 | 2.4e-24 | 80.3 | In-house | 24-284 (302) | alignment | ||
Range on Protein: 305-567
Range on HMM: 24-284/302.0
GQTEMDAEFQRLSRNKAPPSKfqSANLPVNKHKNRYANVLPYDDTRVRLTMQAvtegSDYINANYIDGYMSKKAFIATQAPIPDTI---PDFWRMIWEQD
..|. .||.... |.. | | .||. .| .|...|.|.... .|.|| .. .. | .| |. |. .||||....
dtaevkkefkkidtmkvdlek..Ckafkknlkknqsedvpildsnlvkleaep....dsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqek
CCTIVMLSQEMESGKvKVHRYWP--GKQPTSIGNLVVEMLHDKQFDDYI-MREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQK
. ..|.| .| | | .. ..| . . |.. | .. .. . | | | .. | .| |.. |.. . || . .| ..|
ivsvvilvgeeelkk.tlselfpkksgdykeygkmfvNnrkVekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkik
CgVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
. . |.. |.|| |.| .. . .|.|.... . . ..||..|.|||..|.. .|| . | .| |
a.dentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyiallly
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 376-562 | 3.3e-24 | 80.1 | In-house | 4-198 (199) | alignment | ||
Range on Protein: 376-562
Range on HMM: 4-198/199.0
KKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPT--SIGNLVVEMLHDKQFDDYIMREFKVTN--TKESASRVVRQYQFT
.. .|||| |. .|. |||.|.|| |||. .. .. ||| . . |.| | || . . .|| | ..| . .||||
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
AWPDIGSPDSG--GGLIDLIGQVQ-RWQQKCGvQLTAVHCSAGVGRTGVFCAVSILIERLK--AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQ
.| . .|. |.. .| ...|. |||| | | |||| |. | . . ..||.|. |.||. | .. . ..|.| ||
swkekttpnvalfvgfvvasrevskkyeqekd.apvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 376-562 | 3.7e-24 | 80.0 | In-house | 3-197 (198) | alignment | ||
Range on Protein: 376-562
Range on HMM: 3-197/198.0
KKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPT--SIGNLVVEMLHDKQFDDYIMREFKVTN--TKESASRVVRQYQFT
.. .|||| |. .|. |||.|.|| |||. .. .. ||| . . |.| | || . . .|| | ..| . .||||
qrryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
AWPDIGSPDSG--GGLIDLIGQVQ-RWQQKCGvQLTAVHCSAGVGRTGVFCAVSILIERLK--AEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQ
.| . .|. |.. .| ...|. |||| | | |||| |. | . . ..||.|. |.||. | .. . ..|.| ||
swkekttpnvalfvgfvvasrevskkyeqekd.apvivhcsdgqgftgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiyq
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 152-275 | 1.2e-23 | 78.8 | In-house | 23-140 (145) | alignment | ||
Range on Protein: 152-275
Range on HMM: 23-140/145.0
VELSDYTIRS-FGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEdyGPMVVHCSAGVGRTGTYVVIDAQLKriqaeATVDVYNYV
.| |. |. . . . . .||...||.|. |||||||.. .|.|.. .. . ||..||||||||||||.|... |. |.... .
ellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeg..gpvlVHCsaGvgRtgtlvaaylmll.....lgvsleeal
MMLRGQRNLMVQVEDQYVLIHDVLL
..| || .|. ..|. .....|
elvrsqrpgavpnpgqlrflyefel
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 335-574 | 2e-23 | 77.5 | In-house | 44-282 (312) | alignment | ||
Range on Protein: 335-574
Range on HMM: 44-282/312.0
KHKNRYANVLPYDDTRVRLtmqAvTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQ-------
| ||| |. .| | | | . || ||.. . |..||.|. .|. ||.. ...|..|. .| | |. .|
kdlnrypniqcwdrgrftl...a.gdenfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgsekcakyisdivgfvdled
PTSIGNLVVEM-LHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQqKCgVqltAVHCSAGVGRTGVFCAVSILIE
. . |. . | | | .|| . .||...||| | ||| |. |.. . | | |||||||||| .. . .|
hrvyteycteieiggkskdkithrvlkvvvkatgqesklnhyqwaswpdhgmpdscdtalrllsavkkdk.kp.v...iahcsagvgrtgtlaliesmia
RLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYLHSFDPY
|. .| .. || .| |.. || .. ... |.|.| |
alrhprkqnvkdsfvllrkdrarsvrvfpqyvyalrcvleflyskgly
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 150-272 | 3.4e-23 | 77.4 | In-house | 24-139 (144) | alignment | ||
Range on Protein: 150-272
Range on HMM: 24-139/144.0
STVELSDYTIRSFGVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLteDYGPMVVHCSAGVGRTGTYVVIDAQLkriqaEATVDVYNY
.| .|. .. .. .||...||... |||||||.. . .|.|.. .. . ||..||||||||||||.|... . . .....
llkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale..eggpvlVHCsaGvgRtgtlvaaylmk.....klglsleea
VMMLRGQRNLMVQVEDQYVLIHD
. ..| .| .|. ..|. ...
lalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 459-568 | 3.6e-23 | 76.6 | In-house | 85-194 (440) | alignment | ||
Range on Protein: 459-568
Range on HMM: 85-194/440.0
ESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYE
||...||.. .||| | | | .. .| .|. |.|.| ||||||.||||| || .. | .|.| .. .|..|| |||| |||
giesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnesqekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqtpeqya
FCYQTLGEYL
| .... | |
fvheavlegl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 336-425 | 4.9e-23 | 76.4 | In-house | 49-152 (350) | alignment | ||
Range on Protein: 336-425
Range on HMM: 49-152/350.0
HKNRYANVLPYDDTRVRLT--------MQAVTEGSDYINANYIDGY----MSKKAF--IATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHR
|||| |.|||. .||.| .. ....|||||||. . | ||||||.| |. ||...| . . |..|....| . |..|
aknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdvelnlekcyr
YWPG
||.
YWqe
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 456-562 | 2.6e-22 | 74.5 | In-house | 40-139 (144) | alignment | ||
Range on Protein: 456-562
Range on HMM: 40-139/144.0
NTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgvQLTAVHCSAGVGRTGVFCAVSILIerlkAEAmVDVFQTVKQLREQRPAMVQTKE
.|. | . ||... ||| | ||. |.... ....... ..|||||||||||...| ... . ..........|..|| .|.. .
yepefleregiqylhlpwpDhgvpdllellleflefieealeeg..gpvlVHCsaGvgRtgtlvaaylmk....klg.lsleealalvrsrrpgavpnpg
QYEFCYQ
|..|...
qlrfLle
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 312-568 | 1.2e-21 | 71.6 | In-house | 27-279 (303) | alignment | ||
Range on Protein: 312-568
Range on HMM: 27-279/303.0
EFQRLSRnKAPPSkFQSANLPVNKHKNRYANVLPYDDTRVRLTmqavteGSDYINANYIDGYMSKKAfIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQE
||.... ||| .. | .|||...|. | ..|.|. | || |.|.. |||| | || |.. | |||.|| || ...| .
efekvvs.ylpps.vsknqfvknmdknrfvdvicldhskvkls......dssyihasyleldsskka.iltqlplshtaadfwqmiieqkvkcvlllltd
MESGKVKVHRYWPGKQPT-SIGNLVVEMLHDK---QFDDYIMREFKVTNTKESAsrVVRQYQFTAWPDIGSPDSG-GGLIDLIGQVQRWQQKCGVQLTAV
| |. . .| .| . . .. . | | . .. |.| . . . ... ||| | | .. | |.| .| .|
seydklggdsvfprnqdflkfeersirvgefkrvelgdgwvlkvlsvsngdyks..flhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptv
HCS-AGVGRTGVFCAVSILIERLKAE-AMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
. | .|.||.| |. |..| | .|. . ....|. | || |. . | | |..
ymslsgcgragtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 31-278 | 4.7e-21 | 69.7 | In-house | 36-279 (303) | alignment | ||
Range on Protein: 31-278
Range on HMM: 36-279/303.0
PDTVTSHHSLNqaNRFKNRYNNITAFDHCRVLLQpiegdpTSDYINANYLDgYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCH
| .|. .. .. | |||. .. .|| .| | | || |.||. .. | .| ||. |. |||.|. ||. ...... | .. .
ppsvsknqfvk..nmdknrfvdvicldhskvkls......dssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggd
QYWPSSGS---QNYGVIHVNMMSTVELSD-YTIRSFGVkrSGSPEERMVLQYHYTAWPDHGVPNS--VTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGR
.| . .| | . |||.| .... | | .. .|| ||| .|. | . . | . | | | .|.||
svfprnqdflkfeersirvgefkrvelgdgwvlkvlsv..sngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgr
TGTYVVID-AQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAI
.||. ... |.| . .|..|. . . ..| | || |. ... .| | .
agtfalfetahlslhseqasldlvkclenvrngrlhavqnlsqfsvvytllaehv
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 214-281 | 1.2e-20 | 67.7 | In-house | 1-68 (69) | alignment | ||
Range on Protein: 214-281
Range on HMM: 1-68/69.0
MVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACG
||||||.| |||||.. | .. ||..| ||..| | .| | .|| | .|..||| | ||. |
mvvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 39-275 | 3.2e-20 | 66.7 | In-house | 46-282 (302) | alignment | ||
Range on Protein: 39-275
Range on HMM: 46-282/302.0
SLNQANRFKNRYNNITAFDHCRVLLQpiegDPTSDYINANYLDGYRKQREYIAAQGPLPETC---HDFWRMVWEQNSRVIVMVTNCEERGRiKCHQYWP-
.. ..| ||. ... . |. .| |. .|.|| .. .|. | || | .. .|||||.... .|.. || . ....|
kafkknlkknqsedvpildsnlvkle....aepdsyvnaskvevPeltrsiilaQlpkvdsedsveeFWrmvfqekivsvvilvgeeelkk.tlselfpk
-SSGSQNYGVIHVNMMStVELSDYTIRSF--GVKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDyGPMVVHCSAGVGRTGTYVVI
| ..|| . || || .. . . | | . .. |. | |... || ..... . . | | . | ..|. |.|| |. ..
ksgdykeygkmfvNnrk.VekaeeektryviEvlPegcsnsvlanvyvltnWkqkkvpvkyaeliktaakvfakkikad.entvivSknGaGRagafltl
DAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLL
. ....|... . . . |. .| || .|. .||| .. .||
avaveklqkgkepnikeivksiRsqRpravdslkQyvslyiall
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 215-281 | 1.3e-19 | 64.3 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 215-281
Range on HMM: 1-67/69.0
VVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACG
|||||.| |||||.. | .. ||..| ||..| | .| | .|| |..|..||| | ||. |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 90-257 | 4.2e-19 | 63.6 | In-house | 39-197 (255) | alignment | ||
Range on Protein: 90-257
Range on HMM: 39-197/255.0
IaaqgplpeTCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSGS--PEERMVLQYHYTAWPDHG
. | |.... ... |.||... .| |. ||..|.| . . .||. .| .| .| . . . . | |.|. |...
l........tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWiekn
VPNSVTSVLNFVRkssavnLTEDYGPMVVHCSAGVGRTGTYVVIDAQLK----RIQAEATVDVyNYVMMLRGQR
|. .|| .. . | ..|||||.|.||. ..|... . .. ||.. .|. .|. |
aPelareilnilk......vvrdsksvvvhCstGiGrsaafvlaelvyqkmirsldttetvel.dylslleelr
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 81-270 | 2.6e-18 | 60.5 | In-house | 84-280 (302) | alignment | ||
Range on Protein: 81-270
Range on HMM: 84-280/302.0
DGYRKQREYI-AAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSS--GSQNYGVIHVNMMST-VELSD---------YTIRSFGvKRS
|| |... | .|. .| .. . | ..| ... | . || .|. | ..| |. .| .|.. ||. ..
dGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveikn.ekk
GSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRkssavnLTEDYG-PMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQ
. .. | ...|||||| |. . |. .. | | ..|||||||||||| | | .. . . . |. . |. .| | || |.|
kkkvkktvdilafsawpdhGapkeaytaldilk......fcesykknvlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqq
YVLI
. .
liyl
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 333-560 | 1.2e-17 | 59.0 | In-house | 18-251 (290) | alignment | ||
Range on Protein: 333-560
Range on HMM: 18-251/290.0
VNKHKNRYANVLpYDDTRVRLTMQAVTEGSDYINANYIDgYMSKKAFIATQAPIPDT-------IPDFWRMIWEQDCCTIVMLSQEMESGKVK----VHR
.. ..|... | .||| | .||| ||.. . . ..|.||.| .. | .|| |. . .||| . .| . . .
khemdqRlevpL.veatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCak
YWPGKQPT--SIGNLVVEMLHDKQFDDYIMREFKVTNTKESASRvVRQYQFTAWPDIGSPDSGGGLIDLIGQVQrwQQKCGVqltAVHCSAGVGRTGVFC
| | . . ...| |. . . || ..|| |. .| | ... | .. ... |..|| .|. ..| | ||| |. | ..
YvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeft.vtHsllkgWnklnvqedtktllsliqkvk..asktpv...ivHcvdGiSrsAala
AVSILIERLK-AEAMVDVFQTVKQLREQRPAMVQTKEQYEFC
|. . . . | . . .|.||.|| ........ |
aiilgyQkiaetsgsvkledvlkalrkqralaitsalelafv
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 91-258 | 9.9e-17 | 55.7 | In-house | 42-204 (263) | alignment | ||
Range on Protein: 91-258
Range on HMM: 42-204/263.0
AaqgpLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSGSQNYGVIHVNMMSTVELSDYTIRSFGVKRSG--SPEERMVLQYHYTAWPDHGV
| .| . |.... ... |.||... .| |. || .|.| . . .||. .| || ... . . . | .| |. |...
l....lvqtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWieknd
PNSVTSVLNFVRkssavnLTEDYGPMVVHCSAGVGRTGTYVVIDAQLK----RIQAEATVDVyNYVMMLRGQRN
|. ..|| .. .. . ..|||||.|.||. ..|.. . .. ||.. .|. .|. |.
pelareilnilk......varnskslvvhcstGiGrsaafsvaElvyqkmirsldttstvel.dylsLleelrs
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 505-567 | 1.3e-16 | 55.2 | In-house | 251-314 (319) | alignment | ||
Range on Protein: 505-567
Range on HMM: 251-314/319.0
AVHCSAGVGRTGVFCAVSILIERLKAE-AMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
.|||| ||||||. | | |..|. ||. |.| ..|..| |.||||||| |..| ||
vvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvlsey
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 47-153 | 1.4e-16 | 54.7 | In-house | 51-170 (349) | alignment | ||
Range on Protein: 47-153
Range on HMM: 51-170/349.0
KNRYNNITAFDHCRVLLQP----IEG----------DPTSDYINANYLDGYR--KQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCH
||||..| ..| || |. .. |||||||| | .. ||| | ||| | .||.... .. .... ... .| . ||.
knrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekcd
QYWPSsgsQNYGVIHVNMMSTVE
.|| .| |.| . . .
iywqe...lsysnitvklqnssl
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 371-558 | 1.9e-16 | 54.4 | In-house | 84-278 (302) | alignment | ||
Range on Protein: 371-558
Range on HMM: 84-278/302.0
DGYMSKKAFI-ATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPT--SIGNLVVEML---------HDKQFDDYIMREFKVTNTK
|| |. | .|. .| .| . . . .| |.. .|... |. |. | |. |. . ||. |.| ...|
dGtekkekvskkpivpkkstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkk
ESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCgvqltAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYE
. . | .|.|||| |.|. .|.. . .... ||||||||||| . |. |. . . . |. . |. .|. | ||...|
kkvkktvdilafsawpdhGapkeaytaldilkfcesykknv.....lvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqli
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 506-568 | 3e-16 | 53.5 | In-house | 2-64 (69) | alignment | ||
Range on Protein: 506-568
Range on HMM: 2-64/69.0
VHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
||||.| |||| | |. . . |.|.| .||.| |. .| || || ...| | ...| | |
vhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalveal
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 505-568 | 3.7e-16 | 53.3 | In-house | 2-65 (69) | alignment | ||
Range on Protein: 505-568
Range on HMM: 2-65/69.0
AVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
||||.| |||| | |. . . |.|.| .||.| |. .| || || . .| | . .| | |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalveal
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 503-563 | 3.9e-16 | 53.8 | In-house | 230-290 (297) | alignment | ||
Range on Protein: 503-563
Range on HMM: 230-290/297.0
LTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQYEFCYQT
. |||||||||.|| .....|. . . || ...|||||. .||| ||.|..|.
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellyda
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 202-275 | 8e-16 | 52.6 | In-house | 238-312 (319) | alignment | ||
Range on Protein: 202-275
Range on HMM: 238-312/319.0
SSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAE-ATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLL
|| |..||.||||| ||||||. . | ...... .||. . | .| .| |. .|| .|. ||
ssrsgtresqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvls
|
|||||||||
subfamily_eak_pd | Subfamily eak | 334-479 | 8.6e-16 | 52.2 | In-house | 52-195 (332) | alignment | ||
Range on Protein: 334-479
Range on HMM: 52-195/332.0
NKHKNrYANVLPYDDTRVRLTMQAvTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQ--PTSI
. ..| ...||| |||| . |||| .. . .| | .. | .. ||.|. || .||.| ...| . | .|.| | .
avnrn.vvkivpydrylvrltssq.lnrlGyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkf
GNLVVEMLHDKQFDDYIMREFKVTNTKESasRVVRQYQFTAWPDIGSP
| | || . . . . .| .... |. | |.. | .. |
GildverkefvkrniletrllelskGnet..hrvlhykvfGwtettlp
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 44-282 | 9.9e-16 | 52.7 | In-house | 19-264 (290) | alignment | ||
Range on Protein: 44-282
Range on HMM: 19-264/290.0
NRFKNRYNnITAFDHCRVLLQPIEGDPTSDYINANYLDgYRKQREYIAAQGPLPET-------CHDFWRMVWEQNSRVIVMVTNCEERGRI----KCHQY
. ..|.. .. . . || |. ..||| ||.. . . . |. | |. .. .|| |. . ... .||. . ||. . | .|
hemdqRle.vpLveatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakY
WPSSGS--QNYGVIHVNMMSTVELSDYTIRSFGVKRSGSpEERMVLQYHYTAWPDHGVPNSVTSVLNFVRKssaVNltEDYGPMVVHCSAGVGRTGTYVV
| | ... . |. | .. | .| || . || | . . | . |... ..|. ..| |. |..||| |. | .
vpesvgeelkfkgltvkCkskekeddvetRelvvkfdde.eeftvtHsllkgWnklnvqedtktllsliqk...vk..asktpvivHcvdGiSrsAalaa
IDAQLKRIQ-AEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHD-VLLEAIACGD
|. | . | . . . .|| ||.|... . .. . ..| || .|
iilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivllaievld
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 336-424 | 1.2e-15 | 51.7 | In-house | 50-154 (349) | alignment | ||
Range on Protein: 336-424
Range on HMM: 50-154/349.0
HKNRYANVLPYDDTRVRLTMQ----AVTEG----------SDYINANYID--GYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESGKVKV
|||| ..|||. .||.| .|.. |||||||. . .| .||||||.| |. ||...| . .. |... | . |.
aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddkelslekc
HRYWP
..||
diywq
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 30-139 | 4.5e-15 | 49.9 | In-house | 82-184 (244) | alignment | ||
Range on Protein: 30-139
Range on HMM: 82-184/244.0
SPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQpiEGDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERgrikc
|| . ..| | .||| || || | .| |||| .. . ||| .| || .| |||.|. |. |.|.. ||
rpdpsvmkdafnpnnswknregaglpfdfnrvpls..kgsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....
HQYWPSSGSQ
.||| |
deywpdsepl
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 464-567 | 8.7e-15 | 49.3 | In-house | 216-343 (350) | alignment | ||
Range on Protein: 464-567
Range on HMM: 216-343/350.0
VVRQYQFTAWPDI---GSPDSGGGLID----LIGQ--VQRWQQKCGVQLTAVHCSAGVGRTGVFCAVSILIE-------------RLKAEAMV--DVFQT
|| | |. |.|. | | .. || . . . .. . |||||||||||..... |.. .|. |.. ....
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii
VKQLREQRPAMVQTKEQYEFCYQTLGEY
|..||.|| |||...|. |.|..| |
vnelrkqrismvqnldqfifiYeallfy
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 389-567 | 1.3e-14 | 48.9 | In-house | 40-220 (255) | alignment | ||
Range on Protein: 389-567
Range on HMM: 40-220/255.0
TIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKE--SASRVVRQYQFTAWPDIGSPDSGGGLI
|. |...| .. ..|||. | |..| ..|.| .. |.. | | ..| ..| | . |. |... |.. .|. .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdeklkladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareil
DLIGQVQrwqqKCgvQLTAVHCSAGVGRTGVFCAVSILIE----RLKAE--AMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
.. |. . . ||||.|.||. | . .. |. . .| . ...||..|.. ..| | |. .. ..
nilkvvr....ds..ksvvvhCstGiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldl
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 306-383 | 1.7e-14 | 47.8 | In-house | 22-94 (95) | alignment | ||
Range on Protein: 306-383
Range on HMM: 22-94/95.0
QTEMDAEFQRLSRNKAPPSKFQSANlpVNKHKNRYANVLPYDDTRVRLTMQavtEGSDYINANYIDGYMSKKAFIATQ
. |.| ||. .| | |.. | |||. |..||| ||| || . |||||| ..||| |...||.|
dqefdnefksismtsgapytvgsse..anipknrflnifpydatrvvlttk...rdsdyinacfvdgyarkncyiaaq
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 174-275 | 3.5e-14 | 47.3 | In-house | 216-341 (350) | alignment | ||
Range on Protein: 174-275
Range on HMM: 216-341/350.0
MVLQYHYTAWPDHGV---PNSVTSVLN----FVR--KSSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLK------RIQAE--------ATVDV-YNY
.|.| .. |.| .. |.|. ..|. .. . .. |..||||||||||||.| .| |. .. | | |.
vvyqlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisii
VMMLRGQRNLMVQVEDQYVLIHDVLL
| || || ||| ||.. |.. ||
vnelrkqrismvqnldqfifiYeall
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 3-94 | 1.9e-13 | 44.4 | In-house | 7-95 (95) | alignment | ||
Range on Protein: 3-94
Range on HMM: 7-95/95.0
VDEFEEHVRRLHANGELLFSQEYGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQpieGDPTSDYINANYLDGYRKQREYIAAQG
| | || .|.| . | .|. . . .|| |||. || .| || | |||||| ..||| .. ||||||
vsvfhshvlemhsnsdqefdnefksismtsgapytvgsseanipknrflnifpydatrvvlt...tkrdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 39-125 | 2e-13 | 44.6 | In-house | 31-114 (332) | alignment | ||
Range on Protein: 39-125
Range on HMM: 31-114/332.0
SLNqaNRFKNRYNNITAFDHCRVLLQPIEGDptSDYINANYLDGYRKQREYIAAQGPLPE-TCHDFWRMVWEQNSRVIVMVTNCEERG
|| | || . .||| || | | .| |. ||...||| |. || || |. . | . ||||| |.. .|... . .|.
fln..nmdmnriphlycfdhsrvelapqdgk..ddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekq
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 388-564 | 2.2e-13 | 44.7 | In-house | 45-223 (263) | alignment | ||
Range on Protein: 388-564
Range on HMM: 45-223/263.0
DTIPDFWRMIWEQDCCTIVMLSQEMESGKVKVHRYWPGKQPTSIGNLVVEMLHDKQFDDYIMREFKVTNTKE--SASRVVRQYQFTAWPDIGSPDSGGGL
.||. |...| . ..|||. | |..| .|.| .. |.. | .| ... ....| . . |..|... |.. |
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqsdvllktlellstlgeKkkthtvkhysykgWiekndpelarei
IDLIgQVQRWQqkcgvQLTAVHCSAGVGRTGVFCAVSILIE----RLKAEA--MVDVFQTVKQLREQRPAMVQTKEQYEFCYQTL
. .. .| | . ||||.|.||. | . .. |. .| . ...||..|.. ..| | | ..
lnil.kvarns.....kslvvhcstGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmv
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 322-408 | 1.1e-12 | 42.2 | In-house | 25-116 (347) | alignment | ||
Range on Protein: 322-408
Range on HMM: 25-116/347.0
PPSKFQSANLPVNKHKNRYANVLPYDDTRVRLTMQA-----VTEGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVML
|||| |.. . ||| .| |.||| |. . . |||| .| ..| .| || |.|||. |||.|. .| .
spskftsvewekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
subfamily_eak_pd | Subfamily eak | 51-190 | 1.7e-12 | 41.4 | In-house | 58-196 (332) | alignment | ||
Range on Protein: 51-190
Range on HMM: 58-196/332.0
NNITAFDHCRVLLQPIEGDPTsDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERGRIKCHQYWPSSG--SQNYGVIHVNM
.| .|. | | . .. |||| .. |.|| . . . ||.|| ||.| ||.. . | . | .|.| . ..|...|.
vkivpydrylvrltssqlnrl.GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdktreelkfGildver
MSTVELSDYTIRSFGVKRsGsPEERMVLQYHYTAWPDHGVPN
. |. . . | . ... | | || |.. | . .|
kefvkrniletrllelsk.G.nethrvlhykvfGwtettlpk
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 213-277 | 7.6e-12 | 39.7 | In-house | 230-294 (297) | alignment | ||
Range on Protein: 213-277
Range on HMM: 230-294/297.0
PMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEA
...|||||||||.| | |. |.... . || . .|| || .|| .|. |..|. |.
yllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlkk
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 29-118 | 1.1e-11 | 38.9 | In-house | 24-116 (347) | alignment | ||
Range on Protein: 29-118
Range on HMM: 24-116/347.0
RSPDTVTSHHSlnQANRFKNRYNNITAFDHCRVLLQPIE-----GDPTSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMV
|| .|| . . ||| .. | ||.| | . |.. |||| .. ..||| .| |||.| |||.|| . .| .
yspskftsvew..ekslsknrskdvklidatrvvlspeksknsraddvetyinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvti
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 468-562 | 1.1e-11 | 39.6 | In-house | 86-170 (182) | alignment | ||
Range on Protein: 468-562
Range on HMM: 86-170/182.0
YQFtAWPDIGSPdSGGGLIDLIGQVqrwQQKCGVQLTAVHCSAGVGRTGVFCAVSI-LIERLKAEamvdvfQTVKQLREQRPAMVQTKEQYEFCYQ
|.| .|.| |.. | ..|.. | .. . . .|||| || ||||| |. . .||.|| ...| .|..|| .||.|| |.. .
ynf.gwkDygva.sleriLdivkvv...afalqegkvavhChaGlGrtGvliacylvyakrltae......kaiklvrskrpksiqtreqvelvke
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 466-568 | 4.3e-11 | 38.3 | In-house | 80-177 (194) | alignment | ||
Range on Protein: 466-568
Range on HMM: 80-177/194.0
RQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCAVsILIERLKAeamvDVFQTVKQLREQRPAMVQTKEQYEFCYQTLG
.| .|| |.. | | . . |... ... .. |||| ||.||||...| ||.||. .. . .. .|| || .... ...| .. .
ieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlvaa.YLiyrlgm....saeeAialfrekRpgaipnqdyleallkryk
EYL
|.
elr
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 328-373 | 1.2e-10 | 35.4 | In-house | 33-77 (244) | alignment | ||
Range on Protein: 328-373
Range on HMM: 33-77/244.0
SANLPVNKHKNRYANVLPYDDTRVRLTMqAVTEGSDYINANYIDGY
.| | .| |||| |.||.|.||| |. . |||||||||||.|
navlsanatknryinilpfdetrvilss.skkegsdyinanyiqgs
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 25-82 | 1.4e-10 | 35.1 | In-house | 28-85 (440) | alignment | ||
Range on Protein: 25-82
Range on HMM: 28-85/440.0
YGAFRSPDTVTSHHSLNQANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINANYLDG
. . | . |. . |. |||| || |.||.||.|. ..| | |||||| |..|
wsllpsglsqpsdiaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasying
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 500-568 | 2e-10 | 34.5 | In-house | 264-344 (349) | alignment | ||
Range on Protein: 500-568
Range on HMM: 264-344/349.0
GVQLTAVHCSAGVGRTGVFCAVSILIE----------RLKAEAMV--DVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEYL
. |||||| |||||.. . .|.. ..| .|. .. .| .|| || .||| |. ..|..| .|.
qlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLkyf
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 334-417 | 2.9e-10 | 34.2 | In-house | 34-116 (332) | alignment | ||
Range on Protein: 334-417
Range on HMM: 34-116/332.0
NKHKNRYANVLPYDDTRVRLTMQAVTegSDYINANYIDGYMSKKAFIATQAPIPDTI-PDFWRMIWEQDCCTIVMLSQEMESGKV
| || . .| .|| |. | |. ||...||| | |.| .|||. | ||||. |. |... . | |
nmdmnriphlycfdhsrvelapqdgk..ddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkr
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 370-424 | 3.9e-10 | 33.6 | In-house | 229-280 (440) | alignment | ||
Range on Protein: 370-424
Range on HMM: 229-280/440.0
IDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESgkvKVHRYWP
..|| |.|||||| |. |. ||||.. . ||.|| | . . |||
fegyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywp
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 344-477 | 8.4e-10 | 33.1 | In-house | 3-125 (130) | alignment | ||
Range on Protein: 344-477
Range on HMM: 3-125/130.0
LPYDDTRVRltmqavteGSDYINANYIDGYMSKKAFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESgkvkvHRYWPGKQPTS-IGNLVVEMLHDK
|... .|.. | .||||... . .. ||.|. || |||.|. |. .|.| | ||| .| . .. | |.
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeediivtltdr
QFDDYIMR-EFKVTNTKESASRVVRQYQFTAWPDIG
. ..| .... . . . . .| . || |
defknikasnleiesdlneshqaltmfqisnwpsdg
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 174-276 | 1.9e-09 | 31.3 | In-house | 219-342 (349) | alignment | ||
Range on Protein: 174-276
Range on HMM: 219-342/349.0
MVLQYHYTAWPDHGV---PNSVTSVLNfVRK-------SSAVNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLK----------RIQAEA-TVDVYN-YVM
..|| . |.| .. | |. |. |.. . |.. ...|||||| ||||..| .| | .|. .| . |. |
ellqlqvknwldlslllnPisilqale.vkndliddlfarlyldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivn
MLRGQRNLMVQVEDQYVLIHDVLLE
|| || ||| |.. |.. ||.
elrkqrismvqnlaqfiaiyealLk
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 71-146 | 2.6e-09 | 31.5 | In-house | 12-82 (130) | alignment | ||
Range on Protein: 71-146
Range on HMM: 12-82/130.0
TSDYINANYLDGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERgrikcHQYWPSSGSQNYGVIHV
.||||... . .||. .| || .|. |||.|. |. |.|.. || .||| | .. ..
gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywpdsePlewyeedi
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 329-431 | 6.7e-09 | 28.9 | In-house | 22-92 (169) | alignment | ||
Range on Protein: 329-431
Range on HMM: 22-92/169.0
ANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINAnyidgymskkafiatqapipdtipdfwRMIWEQDCCTIVMLSQEMEsgKvkvHRYWPGKQP
|.| .|. ||| | | |||.| ||||||| ||||| . ||.| . . | .|| |.
aeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtdd..k...nnfwpeked
TSI
.
yql
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 329-435 | 6.7e-09 | 28.8 | In-house | 21-95 (169) | alignment | ||
Range on Protein: 329-435
Range on HMM: 21-95/169.0
ANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINAnyidgymskkafiatqapipdtipdfwRMIWEQDCCTIVMLSQEMEsgKvkvHRYWPGKQP
|.| .|. ||| | | |||.| ||||||| ||||| . ||.| . . | .|| |.
aeltcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtdd..k...nnfwpeked
TSIGNLV
. |
yqlhpav
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 327-373 | 9.3e-09 | 29.1 | In-house | 40-86 (440) | alignment | ||
Range on Protein: 327-373
Range on HMM: 40-86/440.0
QSANLPVNKHKNRYANVLPYDDTRVRLTMQAVTEGSDYINANYIDGY
. |.|| || |||| |.| || .|| | |||||| ||.|
diaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingi
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 43-125 | 9.6e-09 | 28.4 | In-house | 26-81 (169) | alignment | ||
Range on Protein: 43-125
Range on HMM: 26-81/169.0
ANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINAnyldgyrkqreyiaaqgplpetchdfwRMVWEQNSRVIVMVTNCEERG
.| ||| | | || || . | |||||| ||.|| |. |||.. .....
cnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddkn
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 43-125 | 1.2e-08 | 28.0 | In-house | 25-80 (169) | alignment | ||
Range on Protein: 43-125
Range on HMM: 25-80/169.0
ANRFKNRYNNITAFDHCRVLLQPIEGDPTSDYINAnyldgyrkqreyiaaqgplpetchdfwRMVWEQNSRVIVMVTNCEERG
.| ||| | | || || . | |||||| ||.|| |. |||.. .....
cnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddkn
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 171-230 | 2.2e-08 | 29.4 | In-house | 75-134 (194) | alignment | ||
Range on Protein: 171-230
Range on HMM: 75-134/194.0
EERMVLQYHYTAWPDHGVPNSVTSVLNFVRKSSAVNLTEDYGPMVVHCSAGVGRTGTYVV
|.. ..|. .||.|.. | .|.|.. .. | .||| ||.||||| |.
fekagieylklpfpddgtvPsleillrfldlvdeflnedpggvvaVHCkaGlgRtGtlva
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 81-147 | 3.2e-08 | 27.3 | In-house | 230-294 (440) | alignment | ||
Range on Protein: 81-147
Range on HMM: 230-294/440.0
DGYRKQREYIAAQGPLPETCHDFWRMVWEQNSRVIVMVTNCEERgriKCHQYWPSS-GSQNYGVIHVN
.|| |. .||.| || | ||||.| . . |.|. . ... | ||| | .| . |
egyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvg
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 176-272 | 8.4e-08 | 26.8 | In-house | 83-170 (182) | alignment | ||
Range on Protein: 176-272
Range on HMM: 83-170/182.0
LQYHYTAWPDHGVPnSVTSVLNFVRKsSAVNLTEDygPMVVHCSAGVGRTGtyVVIDAQLkrIQAeATVDVYNYVMMLRGQRNLMVQVEDQYVLIHD
. .. .|.|.||. |....|. |. | |.|. . ||| || |||| |.| . | . | .. . . ..| .| .| .| |...
iyvynfgwkDygva.sleriLdivkv.vafalqeg..kvavhChaGlGrtG..vliacyl..vya.krltaekaiklvrskrpksiqtreqvelvke
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 534-565 | 1.6e-07 | 25.4 | In-house | 364-395 (418) | alignment | ||
Range on Protein: 534-565
Range on HMM: 364-395/418.0
VDVFQTVKQLREQRPAMVQTKEQYEFCYQTLG
...| | .|||||| ||| ||| |||.|.
fnlfsivlklreqrpgmvqqleqylfcyktil
|
|||||||||
PTEN_1 | 166-227 | 2e-07 | 26.0 | In-house | 85-146 (196) | alignment | |||
Range on Protein: 166-227
Range on HMM: 85-146/196.0
RSGSPEERMVLQYHYTAWPDHGVPNsVTSVLNFVRKSSAVNLTED-YGPMVVHCSAGVGRTGT
.. . .... ..|. ..|||.|. ... .... | . . .||| ||.||.||
ydleeffksgveylhfpieDhgaps.lselfdicksfiewllsdpngnvVlVHCkaGlgRsGt
|
|||||||||
subfamily_PTEN_pd | Subfamily PTEN | 484-556 | 2.1e-07 | 26.1 | In-house | 97-168 (184) | alignment | ||
Range on Protein: 484-556
Range on HMM: 97-168/184.0
GLIDLIGQVQRWQQKCGVQLTAVHCSAGVGRTGVFCaVSILIERLKAEAMVDVFQTVKQLREQRPAMVQTKEQ
| ... ....| .. .. .||| || ||||| |. |...|. | . .. . .. | . |. |
lleeivediekwleedkknvvvvHCkaGkGRtGvli.vayllkslllekaeealelfaeaRtknkkgvtiPsq
|
|||||||||
PTEN_1 | 490-561 | 1.6e-06 | 23.0 | In-house | 118-186 (196) | alignment | |||
Range on Protein: 490-561
Range on HMM: 118-186/196.0
GQVQRWQQKCG-VQLTAVHCSAGVGRTGVFCAvSILIERLKaeamVDVFQTVKQLREQR-PAMVQTKEQYEFCY
.. | ... .||| ||.||.|. .| . |... | .. .... .||.| |..... .| .. .
ksfiewllsdpngnvVlVHCkaGlgRsGtvva.ayLmykgk....ltadeAlelvrekRppgapnspsqerlle
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 164-259 | 2.5e-06 | 21.2 | In-house | 218-319 (347) | alignment | ||
Range on Protein: 164-259
Range on HMM: 218-319/347.0
VKRSGSPEERMVLQYHYTAWPDHGVPNSVTSVLNFVRK----SSA--VNLTEDYGPMVVHCSAGVGRTGTYVVIDAQLKRIQAEATVDVYNYVMMLRGQR
| | | . | |.|| . |. . || .|| ||. . | |.|| | |. |. | |. .... . | |. . .| ||
vvaegcseatfakvyncttwpwkkypddekkvlalvrapvkesstslianleklapvvvmcdlgldrsatvvltsiiieqvldgktpdcddlfkkmrdqr
NL
ag
|
|||||||||
subfamily_DSP23_pd | Subfamily DSP23 | 504-562 | 3.7e-06 | 21.6 | In-house | 87-140 (148) | alignment | ||
Range on Protein: 504-562
Range on HMM: 87-140/148.0
TAVHCSAGVGRTGVFCAVSILIERLKAEAmvdvfQTVKQLREQRPAMVQTKEQYEFCYQ
.||| | |||| . | .. || | | ... ..|..|| |.| || . ..
vsvhcllgrgrtgtmlacylvkerklaaa.....eaiaevrrlrpgsvetveqeklvrd
|
|||||||||
subfamily_Cele-PTP-5_pd | Subfamily Cele-PTP-5 | 432-567 | 4.6e-06 | 19.5 | In-house | 174-308 (346) | alignment | ||
Range on Protein: 432-567
Range on HMM: 174-308/346.0
GNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPDIGSPDSGGGLIDLIGQVQRWQQKCGVQLTAVhCSAGVGRTGVFCAVSILIERLKAE
|..... . | .| .| | ... .. . | . | .| .| | .| . . | | ||. | |..|
gkmfinnrradvsgdpkeytievlpegnsdsvicqvhhhapwkhlqqppktlpiikmihqflsekqvqnagvcvv.slfgcgracsfigalyainqlnng
AMVDVFQTVKQLREQRPAMVQTKEQYEFCYQTLGEY
.... .|....||| |.. || | . .|
iepniceimknikqqrpggvesfaqyasiyaivfdy
|
|||||||||
subfamily_PRL_pd | Subfamily PRL | 495-551 | 6.2e-06 | 20.3 | In-house | 85-134 (151) | alignment | ||
Range on Protein: 495-551
Range on HMM: 85-134/151.0
WQQKCGvQLTAVHCSAGVGRTGVFCAVSILIERLKAEAMVDVfqtvkqLREQRPAMV
.... . . |||| ||.||. |. |.... . .| | |.. .||.| . .
fkeepk.stvavhcvaGlGraPvlvalalieaGmkyedavef......irekrrgai
|
|||||||||
subfamily_eak_pd | Subfamily eak | 215-285 | 6.6e-06 | 19.7 | In-house | 240-312 (332) | alignment | ||
Range on Protein: 215-285
Range on HMM: 240-312/332.0
VVHCSAGVGRTGTYVVIDAQLKRIQAEAT--VDVYNYVMMLRGQRNLMVQVEDQYVLIHDVLLEAIACGDTEI
.. .. | |.|..|||| .. |.. . | .... . .|. | |. |. .|....|. . . ..
iiqsarGsaraGvfvvidllirlidnkkknlysvedlilkvkskrihsvlvalqhsfiyeivldyllrrnnrl
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 378-477 | 7.1e-06 | 19.8 | In-house | 138-234 (244) | alignment | ||
Range on Protein: 378-477
Range on HMM: 138-234/244.0
AFIATQAPIPDTIPDFWRMIWEQDCCTIVMLSQEMESgkvkvHRYWPGKQPTSI--GNLVVEMLHDKQFDDYIMREFKVTNTKESASRVVRQYQFTAWPD
.| || |. || |||.|. |. .|.| | ||| .| .. | . .| . .... . . . . .| . ||
eyiltqhpladtsmdfwkmmlerhvnvlvvlgsveee.....deywpdseplewyeeditvtltdrdefknikasnleiesdmneshqaltmfqisnwps
IG
|
dg
|