Gene YKR070W in Saccharomyces cerevisiae

Synonym: YKR070W, YKR070W

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold HAD
Superfamily HAD
Family NagD
Subfamily CUT
Protein sequence
ID Type Fasta BLAST phosphatome Note
ScerP044_AA protein Get Run
ScerP044_AA_0-352 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
CECR5_TIGR01456 1-352 9.1e-178 581.3 In-house 26-363 (370) alignment 
Range on Protein: 1-352
Range on HMM: 26-363/370.0
MIGKRFFQTTSKKIAFAFDIDGVLFRGKKPIAGASDALKLLNRN----KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVNKYS-R
.|.|......|||..||.||||||.||||||||||.||..|...    |||..|||||||.|||||.|..|..|.|.|||||.||||.|||.|||||. |
liskvspessskkfgfaldiDGvllrGkkpiagaskalrrLvddqGalkiPvllltngGglseraraeelsalLgvevsplqviqshsPykklvnkyekr

ILAVGTPSVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSGLSDEQVMEYSRDIPDLTTKKFDAVLVFNDPHDWAADIQIISDAINSENgmlntLRNEKSGK
|||.|...|..|||||||..||.....|||.|||.|.|||.||.....|||.|||.||...||||..||.||.||||.|||...||.     |..||.||
ilasGkgevaevaegyGFknvvtvdelvryfrdidplsglvdeerrkksrdlpdldtkrieavlvlsdPvdWeadiqlisDvlrseg.....lpgeklgk

PSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVRRLYLELNGEPLQDYTLGKPTKLTYDFAHHVLIDWEKRLSgkigqsvkqklpllGTKPSTSPFHAVFM
||.|.|.||||||||...||.||||||||||....|....|.||....||||.|||||.|..||||.||||.              |.|.|..||....|
PslpvyisnqDLlwaaeakleRfGqGaFrllletiyqkvtgkpLryellGkPskltydyaedvlidiekrla..............grkgsaapfkklym

VGDNPASDIIGAQNYGWNSCLVKTGVYNEGDDLKECKPTLIVNDVFDAVTKTLEKYA
||||||||||||.|.|..|.|||||||...|.|||.|..|.|..|..||.|.|||.|
vGDnPasDiiGarnaGlfsilvktgvydgadelkegkarlvvdsvseavikiLekea
subfamily_CUT_pd Subfamily CUT 3-352 2.2e-134 438.8 In-house 2-391 (391) alignment 
Range on Protein: 3-352
Range on HMM: 2-391/391.0
GKRFFQTTSKK------IAFAFDIDGVLFRGKKPIAGASDALKLLNRN----KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSLVNK
.|||.||..|.      .....||||||.||||.|..|..|||||...    |.|...|||||.|.|....|..|.||||.|...|...||.|.|.|..|
akrflqtrakrtrsassfgivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkllaek

YS-RILAVGTPSVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSgLSDEQVMEYSRDIPDLTTKKFDAVLVFNDPHDWAADIQIISDAINSENGMLNTLRNE
|. |.|.||..|||.||||.||..||.....|.......|.. ||...|.|.|..... ..||..|......|..|....|.|.|...||...|..|...
ydkrllvvgqesvrevaeglGfknvvtidelvklfphldpvd.lsrrlvqeksselaekelkkieaivllgePvrWetslqlilDvllsegkllrklkll

KSGKPSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVRRLYLELNGEPLQD-YTLGKPTKLTYDFAHHVLidweKRLSGKIGQSvkqklpllgtkpstSPF
..|.|.|||...|.||||....||.|.|.|||.||...|| .|.|..|.. ..||||.||||..|.||.    ||.. |.|..              .|.
tagrphipilacNvDllwmaeaklpRlghGafllllealykkltGkdLryeallGKPskltYqyaehvi....krqakklgle..............dpv

HAVFMVGDNPASDIIGAQNY--------------------------GWNSCLVKTGVYNEGD-------------------DLKECKPTLIVNDVFDAVT
..|...||||.|||.||..|                          ||.|.|||||||.| |                   |||..||.|.||||..||.
kkvyaiGDNPmsDilGAnlyerylrhdgvkkldalgseaqdpsdkegwiSiLVktGvykerdsvekvvkdseadlhghrdldlkllkpslvvndvleAvk

KTL--EKYA
|.|  ||||
kilkkEkya
Subfamily.CECR5.protein 1-352 3.7e-134 438.1 In-house 1-393 (393) alignment 
Range on Protein: 1-352
Range on HMM: 1-393/393.0
MIGKRFFQTTS-------KKIAFAFDIDGVLFRGKKPIAGASDALKLLNRN----KIPYILLTNGGGFSERARTEFISSKLDVDVSPLQIIQSHTPYKSL
.||...|.||.       ||.....||||||.||||.|..|..|||||...    |.|...|||||.|.|....|..|.||||.|...|...||.|.|.|
aigaarflttraartrsakkfgivlDiDGvLlRgkkvipaakealklledkkgelkvPvvfltnggnftekekaeklsekLdvevdadqvllshsPlkll

VNKYS-RILAVGTPSVRGVAEGYGFQDVVHQTDIVRYNRDIAPFSgLSDEQVMEYSRDIPDLTTKKFDAVLVFNDPHDWAADIQIISDAINSENGMLNTL
..||. |.|.||..|||.||||.||..||.....|.......|.. ||...|.|.|..... ..||..|......|..|....|.|.|...||...|..|
aekydkrllvvgqesvrevaeglGfknvvtidelvklfphldpvd.lsrrlvqeksselaekelkkieaivllgePvrWetslqlilDvllsegkllrkl

RNEKSGKPSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVRRLYLELNGEPLQD-YTLGKPTKLTYDFAHHVLidweKRLSGKIGQSvkqklpllgtkpst
.....|.|.|||...|.||||....||.|.|.|||.||...|| .|.|..|.. ..||||.||||..|.||.    ||.. |.|..              
klltagrphipilacNvDllwmaeaklpRlghGafllllealykkltGkdLryeallGKPskltYqyaehvi....krqakklgle..............

SPFHAVFMVGDNPASDIIGAQNY--------------------------GWNSCLVKTGVYNEGD-------------------DLKECKPTLIVNDVFD
.|...|...||||.|||.||..|                          ||.|.|||||||.| |                   |||..||.|.||||..
dpvkkvyaiGDNPmsDilGAnlyerylrhdgvkkldalgseaqdpsdkegwiSiLVktGvykerdsvekvvkdseadlhghrdldlkllkpslvvndvle

AVTKTL--EKYA
||.|.|  ||||
AvkkilkkEkya
Hydrolase_like HAD-hyrolase-like 244-343 1.4e-26 83.5 Pfam-A 2-75 (75) alignment 
Range on Protein: 244-343
Range on HMM: 2-75/75.0
LGKPTKLTYDFAHHVLidwekrlsgkigqsvkqklpllgtkpsTSPFHAVFMVGDNPASDIIGAQNYGWNSCLVKTGVYNEGD-DLKECKPTLIVNDVFD
||||.. .||.|..||                           ..|.  |.|.||..|.||..|.|.|. |.||.|||..|.| .|...||. .|.|. .
lgKPnpgmydkalevl...........................gappsevvmiGDslatDieaAnnaGirsilVltGvsreedlklakakpdyvvddlee

A
|
a
Hydrolase_6 Haloacid dehalogenase-like hydrolase 16-114 8.3e-26 81.3 Pfam-A 1-101 (101) alignment 
Range on Protein: 16-114
Range on HMM: 1-101/101.0
FAFDIDGVLFRGKKPIAGASDALKLLNRNKIPYILLTNGGGFSERARTEFIsSKLDVDVSPLQIIQSHTPYKSLVNK---YSRILAVGTPSVRGVAEGYG
|.||.|||| ||.|.| || .||| |.....|..||||... ||... . . .||.|||.. |...|.|. .....|    ...|..|.  .| ... .|
flfDvdGvLwrgdkaipgaaealkalraagkpvvllTNnsskseeeyakkl.eklgvdvteeqvvtsataaaeylkkrkadkkvlvigeeglreelkeaG

FQ
|.
fk
subfamily_LHPP_pd Subfamily LHPP 290-327 1.7e-08 25.7 In-house 189-226 (227) alignment 
Range on Protein: 290-327
Range on HMM: 189-226/227.0
FHAVFMVGDNPASDIIGAQNYGWNSCLVKTGVYNEGDD
 . . |.||.  .|. ||.. | .. |||||.. ..|.
peeavmiGDdvedDveGAlkaGlrgvlVktGkfrpede
Chronophin_1 17-64 2.1e-08 24.9 In-house 5-49 (261) alignment 
Range on Protein: 17-64
Range on HMM: 5-49/261.0
AFDIDGVLFRGKKPIAGASDALKLLNRNKIPYILLTNGggfSERARTE
 .|.||||..|.. ..||..... |... . .. .||    | |.|.|
LlDldGVlikgeeavpgAaeliealkqagkevlfvtNn...srrtree
subfamily_PGP_pd Subfamily PGP 16-83 3.6e-07 20.8 In-house 2-69 (279) alignment 
Range on Protein: 16-83
Range on HMM: 2-69/279.0
FAFDIDGVLFRGKKPIAGASDALKLLNRNKIPYILLTNGGGFSERARTEFIsSKLDVD-VSPLQIIQSH
. ||.|||| .|...| || .||. |..     ...|| .  |..  .. .  || .. |.  .|..| 
vlfDcDGVlWlgetaipgaaealnaLkklgKkvlfvtNnstksreellkkf.kklgfekvkeeeilssa
Chronophin_1 292-345 2.7e-06 18.0 In-house 201-257 (261) alignment 
Range on Protein: 292-345
Range on HMM: 201-257/261.0
AVFMVGDNPASDIIGAQNYGWNSCLVKTGVYN--EGDDL-KECKPTLIVNDVFDAVT
.. ||||    ||  ... | .. || ||| .  |  .  |...|. .|... | . 
etvmvGDRldTDilagaraglstllvltGvseleeaqaykkdlrPdavvesiadlle
subfamily_LHPP_pd Subfamily LHPP 18-91 3.4e-06 18.1 In-house 3-75 (227) alignment 
Range on Protein: 18-91
Range on HMM: 3-75/227.0
FDIDGVLFRGKKPIAGASDALKLLNRNKIPYILLTNGGGFSERARTEFIsSKLDVDVSPLQIIQSHTPYKSLVN
 |. |||. ....|.|| .||| | ....   ..||    |.|| .| . ..|. ||.  .|. | .   .|..
lDlsGvlhnedaaipgavealkrLrqagvkvrfvtNttkeskralverL.irlgfdveeeeiftsleaarqllr
Chronophin_2 17-67 7.2e-06 16.5 In-house 4-51 (282) alignment 
Range on Protein: 17-67
Range on HMM: 4-51/282.0
AFDIDGVLFRGKKPIAGASDALKLLNRNKIPYILLTNGggfSERARTEFIS
 || |||.. |.| .|||.. ...| |     ...||    | ||| ... 
lfdcdgviwngekavagapevvsrlaragknvlfvtnn...strarenyvl
subfamily_PGP_pd Subfamily PGP 290-329 8.5e-06 16.3 In-house 217-256 (279) alignment 
Range on Protein: 290-329
Range on HMM: 217-256/279.0
FHAVFMVGDNPASDIIGAQNYGWNSCLVKTGVYNEGDDLK
.. . |.||  ..||  ..| | .. || .||... |  .
pertlmiGDrlktDilfgkncGlqtLlvlsGvtkledvee