Gene DSP19 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family DSP
Subfamily DSP19
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP014_AA protein Get Run
SpurP014_AA_355-499 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_DSP19_pd Subfamily DSP19 369-497 5.1e-57 186.5 In-house 22-151 (152) alignment 
Range on Protein: 369-497
Range on HMM: 22-151/152.0
ASCDVAYNLEILKYHNITHILNVA-NLNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISK
.|.|||.. ||||...|||||||| ...||.|..|||....|.|||| ......|.|.|||..|||. |.||||||||.|||...|..|....|......
gsqdvaadkeilkekkitHilnvatgvpnvfpkdftylsieilDlpetdllsylkealdFieearskdgavlvHCnAGvSRsasvviaylmkkeelslee

TLEEIRVHRPCVRPNEGFMRQLEEYETSIL
.||..| .|||..|||||..||.|||...|
alelvrearpcikPneGFikqLkeyeaell
subfamily_DSP1_pd Subfamily DSP1 370-499 4.4e-40 131.4 In-house 29-159 (163) alignment 
Range on Protein: 370-499
Range on HMM: 29-159/163.0
SCDVAYNLEILKYHNITHILNVAN-LNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKT
|. || |||||| ..||.||||.. |.||..|.|.||.|.. | |.  |.. |. .|.||.......|.||.||.|| |||.|... |..  .| .... 
setvasnleiLkslgitailnvskeldnvfedlfeYkklkleDspkadislvfeeviefidevkkknGkvlihCqaGisRsstlclaylmktkrvsleea

LEEIRVHRPCVRPNEGFMRQLEEYETSILAE
 . .. .|....|| ||..|| .||...|.|
fdfvkqrRsiisPnagFvlqLlnyekkllle
subfamily_DSP15_pd Subfamily DSP15 373-499 8.8e-34 110.8 In-house 16-142 (151) alignment 
Range on Protein: 373-499
Range on HMM: 16-142/151.0
VAYNLEILKYHNITHILNVANLNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEI
.. . | || .||||||.| . .. . ....|| ... | |..|..|||| ...|| ..|. .. ||||| || |||.|.|| |...       ..|| |
dskdeelLkeknithilsvhdnakkllkdieYkciaasDtpsaklskffkesvefihkcRlkeenvlvhClaGvsRsvtlvvaYlmtvtelnwrdalevi

RVHRPCVRPNEGFMRQLEEYETSILAE
. .| .  || || |||.|||.. |.|
kaaRsvanPnfGfkrqlkeyektklke
subfamily_DSP10_pd Subfamily DSP10 374-496 2.9e-33 109.0 In-house 29-153 (159) alignment 
Range on Protein: 374-496
Range on HMM: 29-153/159.0
AYNLEILKYHNITHILNVANL-NNVY-PDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEE
| .|..|. .|||..|||..   | .  ....|| .|. |  . .. . |. |..||..||..| ||||||.|| |||.|.|..|...  .  ...  . 
aadldaldrlnitavlnvttsvPnefeeealkYkripvsDtskqnlkqyfeealefieearkkgsrvLvhCqaGisrsatvviaYlmkhlnlslndaykf

IRVHRPCVRPNEGFMRQLEEYETSI
... || . || .|| || |.| ..
vkekrpiisPnLnfmGqLlefekel
0044763 (Phosphotyrosine protein) phosphatases II 370-498 7.8e-33 109.0 In-house 34-172 (178) alignment 
Range on Protein: 370-498
Range on HMM: 34-172/178.0
SCDVAYNLEILKYHNITHILNVANLNNVY-PDH---------FTYKNLPIWDLPEVKITKFFKYAIDFINQAR-STGGRVLVHCNAGRSRSTTIVVGYIL
|.  | .|| || ..||||.|...    . ...         ..|...|| | ..  ....|  ...||..|. . ||.|||||.||..||.|.|. |..
slppaddlellkelgithivnlteelelgflkcdpywpeeagiqylhipipDhgvpdllehflefvefieealdekggpvlVHCsaGvgRsgtlvaaylm

ADERARISKTLEEIRVHRPcVRPNEGFMRQLEEYETSILA
   .  . . .|..| .|| . ||.|..|||.|.|  .|.
kklglsleeaielvrerRp.ivpnpgqlrqLyefelrllk
subfamily_Slingshot_pd Subfamily Slingshot 374-498 1.3e-32 106.5 In-house 34-159 (169) alignment 
Range on Protein: 374-498
Range on HMM: 34-159/169.0
AYNLEILKYHNITHILNVA-NLNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEI
| ||| || .....||||. ...| .|..|.|.|. ..| .| .. |... . .||..|...| .|||||  | |||...|. | . . .  . ..|| .
asnleelkengveyilnvtkeidnffpekfeylnirvydeeetdllkywnetykfiekakkkgskvlvhckmGvsrsastviayamkeyglsleealeyv

RVHRPCVRPNEGFMRQLEEYETSILA
. .| ...||.||..||||||  . |
kerrsvikPnkgflkqleeyeGilea
PTPc_motif_SM00404 370-494 2.7e-32 106.6 In-house 13-139 (140) alignment 
Range on Protein: 370-494
Range on HMM: 13-139/140.0
SCDVAYNLEILKYHNITHILNVANLNNV--YPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISK
|.. | |...|| ..|||..||..  ..     .|.....|. |  . |..|... ..|||..|...||.||||| || ||| |... |..  .   ...
skskaqnpallkklgithvinvteevsltkensgfqilqiplddnekdklskyldkvldfienaekkggkvlVHCqaGvSRSatliiaYlmryrqlslae

TLEEIRVHRPCVRPNEGFMRQLEEYET
 .| ... ||...||..|.||| |||.
ayefvkerRpiispnlnfvrqLieyek
subfamily_LRR-DSP_pd Subfamily LRR-DSP 371-496 2.4e-31 102.8 In-house 132-258 (263) alignment 
Range on Protein: 371-496
Range on HMM: 132-258/263.0
CDVAYNLEILKYHNITHI-LNVANLNNVYPDHFTYKNL-PIWDLPEVKITKFFKYAIDFINQARSTGGrVLVHCNAGRSRSTTIVVGYILADERARISKT
 | | |  |||  ..||| | ||... ..|. | |  .  | | .| .| ..|.    ||.. |  || ||||| || |||.|.|. |..  .| .  ..
ldsannksilkdlgvthillavadfePlfPklfkylsiddiedvdeadisqhfeetnafieeGrkkGG.vlvhcraGvsrsstlvisylmkkqrlkfkea

LEEIRVHRPCVRPNEGFMRQLEEYETSI
|. .  .|| ..|| ||. ||  ||  .
ldlvikkrpriqPnpGfkdqlkkyekkl
0048076 (Phosphotyrosine protein) phosphatases II 370-495 3.4e-31 103.2 In-house 15-141 (145) alignment 
Range on Protein: 370-495
Range on HMM: 15-141/145.0
SCDVAYNLEILKYHNITHILNVA-NLNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKT
|. .|..|| || ..||..||.. .|..... ...| .||..| ..  .....  ...||..|.. ||.|||||.||..|..|.|. |..  ..  . ..
slptaldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealkeggpvlVHCsaGvgRtgtlvaaylmlllgvsleea

LEEIRVHRPCVRPNEGFMRQLEEYETS
||..| .||.. ||.|..|.|.|.|. 
lelvrsqrpgavpnpgqlrflyefele
DSPc Dual specificity phosphatase, catalytic domain 377-494 7.5e-31 101.8 Pfam-A 11-132 (133) alignment 
Range on Protein: 377-494
Range on HMM: 11-132/133.0
LEILKYHNITHILNVAN-LNN---VYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEI
|..|. ..||...||..  .|     . ...| ..|. |  | ||.|... |..||..|.. |..|||||.|| ||| |... |..  .. .... .| .
lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefv

RVHRPCVRPNEGFMRQLEEYET
.  |....||.||.||| |||.
kerrskispnagflrqLleyer
DSPc Dual specificity phosphatase, catalytic domain 377-494 7.5e-31 101.8 In-house 11-132 (133) alignment 
Range on Protein: 377-494
Range on HMM: 11-132/133.0
LEILKYHNITHILNVAN-LNN---VYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEI
|..|. ..||...||..  .|     . ...| ..|. |  | ||.|... |..||..|.. |..|||||.|| ||| |... |..  .. .... .| .
lalleklgitlvinvtkevpnnnaikkseieylripvedetetkiskeleeavefiekaeqkgkkvlVHCqaGisRSatliiaYlmktknlslneAyefv

RVHRPCVRPNEGFMRQLEEYET
.  |....||.||.||| |||.
kerrskispnagflrqLleyer
subfamily_DSP14_pd Subfamily DSP14 371-497 1.9e-30 99.9 In-house 18-145 (157) alignment 
Range on Protein: 371-497
Range on HMM: 18-145/157.0
CDVAYNLEILKYHNITHILNVA-NLNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTL
. .| . | || ..||.|.||. .|.|   ... . ..|. | ||.|..|.|  ..| |.... .||..|||| ||.||| .... |..  |.  . .. 
gvaalskellkkkkitliinvtvelpntklkdiervkvpveDnpeaklakhfdevadkieevkkkggktlvhCvaGvSRSAslclaylmkyeklsLreay

EEIRVHRPCVRPNEGFMRQLEEYETSIL
. .. .|| .||| || .|| .||. . 
klvksaRpiirPNvGFwkqlidyEkklk
subfamily_DSP6_pd Subfamily DSP6 373-496 3e-30 98.8 In-house 28-154 (158) alignment 
Range on Protein: 373-496
Range on HMM: 28-154/158.0
VAYNLEILKYHNITHILNVA-NLNNVYPD--HFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTL
 | |||.|| ..| ..|||. ||.|.. .  ...|...|| |  . ...|||  ||.||..|||.   ||||| || ||| |... |..  .   . .. 
dasnlevlkklkikyvlnvtsnlpnkfeesgelkylqipiedhlsqnlakffPeaiefidearskkskvlvhClaGisrsvtvtlaylmkklalslnday

EEIRVHRPCVRPNEGFMRQLEEYETSI
. .. ... . ||  || || ..| |.
dlvkkrksnisPnfnfmgqlldfersl
0048179 (Phosphotyrosine protein) phosphatases II 370-494 4.5e-30 99.6 In-house 15-142 (144) alignment 
Range on Protein: 370-494
Range on HMM: 15-142/144.0
SCDVAYNLEILKYHNITHILNVAN---LNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARIS
|. .|..|| || ..||...|...    . . . ...| .||. | .   .....  ...||..|.. ||.|||||.||..|..|.|. |..  ..  . 
slptaldlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieealeeggpvlVHCsaGvgRtgtlvaaylmkklglsle

KTLEEIRVHRPCVRPNEGFMRQLEEYET
..|...| .||.. ||.|..|.|.|||.
ealalvrsrrpgavpnpgqlrfLleyek
0049772 (Phosphotyrosine protein) phosphatases II 359-495 5.7e-30 100.5 In-house 155-272 (314) alignment 
Range on Protein: 359-495
Range on HMM: 155-272/314.0
QkieetgrqeaSCDVAYNLEILKyhnithilNVANLNNVYPDH-FTYKNLPIWDlPEVKITKFFKYAIDFINQArSTGGRVLVHCNAGRSRSTT-IVVGY
.          .  .| .|| ||        .. . .. .... ..|...|..| ... ....|. ...||..| ..||.|||||.||..|..| .|..|
g..........neptaadlellk........eelydpelferlgikylripvpD.gsaplledfdeflefieea.dkggpvlvHCkaGkgRtgtfvvaay

ILADERARISKTLEEIRVHRPcVRPNEGFMRQLEEYETS
..   .  . ..||..|  || ..||.||..|||.||  
lmkllgvsleealedvrlkRp.inpnpgfieqleqyefi
subfamily_DSP12_pd Subfamily DSP12 376-495 1.5e-29 97.4 In-house 19-142 (155) alignment 
Range on Protein: 376-495
Range on HMM: 19-142/155.0
NLEILKYHNITHILNVANLN----NVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEE
. | ||  .|||.| |.. .    .  . . ..|...| | ||. | ...  |.|||..|....| |||||.|| ||| |||. |..  |.  ..| |. 
eeellkelkithvlsvikeelpehklkkgkvstkfiqilDepeediLshldeavdFieealeeegavlvHCqagvSRSvtiviAYlmkkeklslekAlkl

IRVHRPCVRPNEGFMRQLEEYETS
..  .| ..|||||..||  .| .
vkekkpeiepNegFleQLklfekm
0043147 (Phosphotyrosine protein) phosphatases II 370-495 1.8e-29 98.0 In-house 30-159 (172) alignment 
Range on Protein: 370-495
Range on HMM: 30-159/172.0
SCDVAYNLEILKYHNITHILNVAN----LNNVYPDHFTYKNLPIWDLPEVkITKFFKYAIDFINQ--ARSTGGRVLVHCNAGRSRSTTIVVGYILAdERA
....| ... || ..||||.|. .      ....  ..|  ||. | .   .....  ...||..  |.| ||.||||| || .|. |.|. |..  .. 
rntladfwrmlkelgithivnltellydpellerlgiqylylpwpDhgvp.llellleflefidellalspggpvlVHCsaGvgRtgtlvaaylml.lgl

RISKTLEEIRVHRPCVRPNEGFMRQLEEYETS
 . ......| .||.. .|....|.| ..|  
sleeavalvrekRpgavqnpsqyrflyyfekl
subfamily_DSP3_pd Subfamily DSP3 372-496 1.6e-28 93.4 In-house 24-157 (162) alignment 
Range on Protein: 372-496
Range on HMM: 24-157/162.0
DVAYNLEILKYHNITHILNVANL--NNV------YPD-HFTYKNLPIWDLPEVKITKFFKYAIDFINQARST-GGRVLVHCNAGRSRSTTIVVGYILADE
.|| . . ||   |||.|| |.   ..|      | | ...|  |.. | ||... |.|. | .||..| |.  |.|||||..| |||.|.|. |..  .
avakdkskLkklGithvlnaaegrfskvdtgaefykdleikylGlevdDvpefdlskyFetaakfidealsqkegkvlvhcvvGvsRsatlvlayLmirr

RARISKTLEEIRVHRpCVRPNEGFMRQLEEYETSI
.  . . ....| .| ...|||||..|| |.....
kmtlveairtvrkkR.eilPneGFlkqLaeldeel
subfamily_Dicty-DSP19-like_pd Subfamily Dicty-DSP19-like 370-495 6.1e-28 91.1 In-house 14-151 (154) alignment 
Range on Protein: 370-495
Range on HMM: 14-151/154.0
SCDVAYNLEILKYHNITHILNV-ANLNNVYPDH---------FTYKNLPIWDLPEVKITKFFKYAIDFINQAR--STGGRVLVHCNAGRSRSTTIVVGYI
| | |.|   |. .||..||||    ||...|.         . | || ..| .. .|.. .. | .||..|      ..||||...| |||......|.
sfdaalnkldlqlkniksilnvgiGinnlftdensdindgfiieylnlelfddvnfdiiekldkafefiddaiggvennkvlvhsdkGvsrsaallisyl

LADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYETS
.   .  .|..|| ..  |. ..||.||..||| .|  
mdklkislslalellkdsryiikPnqGflkqleifeke
0045098 (Phosphotyrosine protein) phosphatases II 373-496 1.7e-27 91.9 In-house 77-271 (278) alignment 
Range on Protein: 373-496
Range on HMM: 77-271/278.0
VAYNLEILKYHNITHILNVA-----------------------------------------------------NLNNVYPDHFTYKNLPIWDLPEVKITK
|| ... |. ..||.|....                                                     .| . .  |. |.. |  . |.  |.|
vadfwrmlwelgitvivmltelvelgrekcaqywpeggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilk

FFKYAIDFINQARS--------------TGGRVLVHCNAGRSRSTTIVVGYILADE---RARISKTLEEIRVHRPC-VRPNEGFMRQLEEYETSI
.|  ...||..|..               ||.|||||.|| .|. |.|. |.. .    .  . ....|.| .||. . .|....|.|.|..  .
sflellefirealkllaslllsslllldsggpvlVHCsaGvgRtGtlvaaylmlelleggvdlleavkelrsqRpglavqnleqyrflyefllel
0041856 (Phosphotyrosine protein) phosphatases II 372-495 2.6e-27 91.0 In-house 46-171 (182) alignment 
Range on Protein: 372-495
Range on HMM: 46-171/182.0
DVAYNLEILKYHNITHILNVAnLNNVYPDHF-----TYKNLPIWDLPEVKitkfFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARIS
.|| .|. || ..||.|.|..   . .|...     .|..||. | .       .  ..|||..... ||.|||||.||..|. |.|. |..   .  . 
tvadflrmlkelgittivnlt.eelywpellerlgiqylylpwpDhgvpd....ldelldfieevleeggpvlVHCsaGvgRtgtlvaaylmkklgvsle

KTLEEIRVHRP--CVRPNEGFMRQLEEYETS
......| .||  ...|| .|..|| ..|  
eavklvrsrRpgmvitpnqyfflqlallell
0045450 (Phosphotyrosine protein) phosphatases II 378-494 4.5e-27 91.0 In-house 125-301 (307) alignment 
Range on Protein: 378-494
Range on HMM: 125-301/307.0
EILKYHNITHILNVANLNNV-----------------------------YPDHFTYKNLPIWDL-----------------PEVKITKFFKYAIDFINQA
. |. ...|.|... .|                                . |..|. .|...||                 |. .. ..|. ..|||...
rmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieev

RS------TGGRVLVHCNAGRSRSTTIVVGYILADER--------ARISKTLEEIRVHRPCVRPNEGFMRQLEEYET
|.       ||.|||||.|| .|. |... |.. . .          . ......| .||.. .|....|.| |.. 
rkaleelpkggpvlVHCsaGvgRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeall
0049260 (Phosphotyrosine protein) phosphatases II 371-494 5.4e-27 89.8 In-house 20-147 (152) alignment 
Range on Protein: 371-494
Range on HMM: 20-147/152.0
CDVAYNLEILKYHNITHILNVANLNNV----YPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQ-ARSTGGRVLVHCNAGRSRSTTIVVGYILAdERARI
 ..| ... || ..||.|... .|        . ...|..||. | .  ... ... ...||.. |.. ||.||||| || .|. |.|. |..   .  .
ntladfwrmlkelgittivmltellelgklkceqyiqylhlpwpDhgvpdlsqlllflllfieklaldkggpvlVHCsaGvgRtgtlvaaylml.lgvsl

SKTLEEIRVHRPCVRPNEGFMRQLEEYET
 .... .| .||.. ||.|..|.| |.|.
eeavalvrekRpgavpnpgqlrflyefek
subfamily_MKPLT_pd Subfamily MKPLT 372-497 6.4e-27 88.1 In-house 35-161 (164) alignment 
Range on Protein: 372-497
Range on HMM: 35-161/164.0
DVAYNLEILKYHNITHILNVAN-LNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLE
. | | ..||  .||||.||..  .. .|  . | .. . | .. ....|.. | .|. .|  .||||||||. |.|||... | ...  ..  . .. |
khatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeaye

EIRVHRPCVRPNEGFMRQLEEYETSIL
 ..  | .|.|| ||..|| ..|  ||
ylkerrsivapnrGflkqlakfeelil
subfamily_MKPLV_pd Subfamily MKPLV 372-497 6.4e-27 88.1 In-house 35-161 (164) alignment 
Range on Protein: 372-497
Range on HMM: 35-161/164.0
DVAYNLEILKYHNITHILNVAN-LNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLE
. | | ..||  .||||.||..  .. .|  . | .. . | .. ....|.. | .|. .|  .||||||||. |.|||... | ...  ..  . .. |
khatnekvlkdlkithivnvsqekkdafpksveYlqvkvedesdeqlssfleraakfladaidsGGrvlvhcvqGksrsssvtvafLikskgwtlkeaye

EIRVHRPCVRPNEGFMRQLEEYETSIL
 ..  | .|.|| ||..|| ..|  ||
ylkerrsivapnrGflkqlakfeelil
PTEN_1 356-499 3.9e-26 87.1 In-house 42-194 (196) alignment 
Range on Protein: 356-499
Range on HMM: 42-194/196.0
KakqKIEETGRQEASCDVAYNLEILKYHNITHILNVANLNN----------VYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARS--TGGRVLVHCN
.   .|.|.  ..   ||| .|. || ..||...|...  .           .  ...|...|| | .   . ..|. . .||....|   |. ||||| 
q...eideglyrgslkdvaadldnlkedgitlvvnlseeeelsgrsydleeffksgveylhfpieDhgapslselfdicksfiewllsdpngnvVlVHCk

AGRSRSTTIVVGYILADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYETSILAE
||..|| |.|  | .. ..    ..|| .| .||...|| .....|.||. ..|||
aGlgRsGtvvaayLmykgkltadeAlelvrekRppgapnspsqerlleyfaellae
0046846 (Phosphotyrosine protein) phosphatases II 372-494 1.1e-25 85.8 In-house 35-170 (176) alignment 
Range on Protein: 372-494
Range on HMM: 35-170/176.0
DVAYNLEILKYHNITHILNVANL--------NNVYPD----HFTYKNLPIWDLPEVKItKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILA
..| .|| || ..||...|. ..         | .|.    ...|..||. |     . . .  ...||..|.. ||.||||| ||..|. |.|. |.| 
tladflemlkelgitavvnlteevelgrlkcpnywpeleklgiqylhlpwpDhgvpdl.elllellefirealkeggpvlVHCsaGigRtgtlvaaylle

D-ERARISKTLEEIRVHRP-CVRPNEGFMRQLEEYET
      . ..|...| .|| .. ......|.|.|.| 
lekglsveealalvreqRplgavqtpeQyrflyefel
0040439 (Phosphotyrosine protein) phosphatases II 371-494 2e-25 85.3 In-house 65-243 (249) alignment 
Range on Protein: 371-494
Range on HMM: 65-243/249.0
CDVAYNLEILKYHNITHILNVANLNN--------------------------------------------VYPDHFTYKNLPIWDLPEVKITKFFKYAID
  |. ... |. ..||.|... .|                                               .....|.. ... |.|. .. ..|. ..|
etvedfwrmlwelgitvivmLtslvelgrekcaqywplggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlld

FINQARS------TGGRVLVHCNAGRSRSTTIVVGYIL-----ADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYET
||...|.      .||.|||||.|| .|. |... |..        .  .  .....| .||.. .|....|.| |.. 
fieavrkaleelpkggpvlVHCsaGvgRtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeall
subfamily_Choan-DSP_MKP-1_pd Subfamily Choan-DSP_MKP-1 372-494 1.6e-24 80.1 In-house 21-145 (148) alignment 
Range on Protein: 372-494
Range on HMM: 21-145/148.0
DVAYNLEILKYHNITHILNVA-NLNNVYPDHFT-YKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTL
  | .|| ||  ..|.| | . . .|.. ..   | .... | |.  . ..|. .|.|...|.. |.|||||.. |.|||. ... ...  .|  . . |
ksaadlealkalgvtrivnatkerdnaldqrgieYlhvaldDkpkedlsaiFediiafvrkakdeGrrvLvhlqmGvsrssalallwlidfkrvslkeal

EEIRVHRPCVRPNEGFMRQLEEYET
. ..  |. |.|| ||..|| |.| 
alvkskrryvdpnlgfLkqLaeleq
0037934 (Phosphotyrosine protein) phosphatases II 345-494 5.2e-24 80.6 In-house 13-239 (243) alignment 
Range on Protein: 345-494
Range on HMM: 13-239/243.0
KNRCHGPIPLSKAKQKIEETGRQEASC--------------------DVAYNLEILKYHNITHILNVAN-------------------------------
|||  . .|.     |.| ..   |.                     |.| ... |. ..||.|... .                               
knrysdilpydhsrvklegsdyinanliyvtprliatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywpgevtygdftvtllseeh

---------------LNNVYPDHFTYKNLPIWD----LPEVKITKFFKYAIDFINQ-----ARSTGGRVLVHCNAGRSRSTTIVVGYILADE-RARISKT
               |....  .. |  ||. |         . .|......||..     |...||.||||| ||..|. |... |.. .  .  . ..
lddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaGvgRtGtliaaylmllllgvdleea

LEEIRVHRPC-VRPNEGFMRQLEEYET
....| .||. . ......|.| |.. 
vkllreqRpgkavqtpsqyrflyeall
0040438 (Phosphotyrosine protein) phosphatases II 377-493 9.6e-24 79.6 In-house 103-272 (317) alignment 
Range on Protein: 377-493
Range on HMM: 103-272/317.0
LEILKYHNITHILNVANLNNV----------------------------YPDHFTYKNLPIWDL----------------PEVKITKFFKYAIDFINQAR
.. .. ...|.|... .|                               . ...|. .|...||                |. .. . ..  .||....|
wrmvweqgvtvivmLteleelgrekcaqYwplgetltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavr

ST----GGRVLVHCNAGRSRSTTIVVGYIL-----ADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYE
.     || |||||.|| .|. |... |..       ..  . ....|.| .||.. ......|.| ...
ealedpggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydal
subfamily_STYX_pd Subfamily STYX 375-499 3.5e-23 75.5 In-house 30-160 (166) alignment 
Range on Protein: 375-499
Range on HMM: 30-160/166.0
YNLEILKYHNITHILNVAN------LNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKT
  ||.|| | ||||. . .      .   .||.| |  | . | .  .| ...    .||... ..||.|||| ||| |||...|..||.     .  ..
sklevlkkhgithivcirqnieanlikpnfpdrfrylvldvadntveniirylptvkefiddslqkggkvlvhgnagisrsaalviayimetyglkyrea

LEEIRVHRPCVRPNEGFMRQLEEYETSILAE
   .. .| |. |||||..||.|||.  ||.
fayvqerrfcinpnegfvsqlkeyeaiylak
0036282 (Phosphotyrosine protein) phosphatases II 374-493 2e-22 75.1 In-house 27-166 (174) alignment 
Range on Protein: 374-493
Range on HMM: 27-166/174.0
AyNLEILKYHNITHILNVANLNNV----------------YPDHFTYKNLPIWDLPEVKITKfFKYAIDFINQARST--GGRVLVHCNAGRSRSTTIVVG
| ..| || ..||..... ...                  .. ...|. ||. |  .  ... .  ...|...|.|   || |||||.||..|. |.|. 
a.fwemlkelgittvvmlleekelglykcinywpelredlerlgiqylylpwpDhgvpdlsi.llefvkfveealsedpggpvlVHCsaGvgRtGtlvaa

YILADERA-RISKTLEEIRVHR---PCVRPNEGFMRQLEEYE
|..      .  . |. .|  |   |.. ......|.| ..|
ylmlrglleslvdaldlvrelRlqrpgmvqtpsQyrflyyfe
0051082 (Phosphotyrosine protein) phosphatases II 373-492 2.4e-22 74.6 In-house 22-149 (151) alignment 
Range on Protein: 373-492
Range on HMM: 22-149/151.0
VAYNLEILKYHNITHILNVANLN------NVYPD-HFTYKNLPIWDLPEVKITKFFKYAIDFINQARST-GGRVLVHCNAGRSRSTTIVVGYILAdERAR
 | .|| || ..|..|.|. ..       . .|.  ......||.| |. ..  .|. ...|....... .| |||||.||..|. |.|. |... ..  
ladflellkelgiktivnlrseeergycpeylpelgievlhipildwpdpglplsfdavleflellldkkngpvlvHCsaGkgRTGtlvalylml.lgvs

ISKTLEEIRVHRP-CVRPNEGFMRQLEEY
. ..|||.| .|| .|.||..|. || ..
leealeeyrlkrpgvvqpnqqflfqlfal
subfamily_DSP8_pd Subfamily DSP8 375-497 3.3e-22 72.8 In-house 31-155 (159) alignment 
Range on Protein: 375-497
Range on HMM: 31-155/159.0
YNLEILKYHNITHILNVANLNN--VYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEI
 . |.|.  .|...||. |         .  .  .|. |  . |.  .|. ...||..|.|. ||||||. ||.|||.|....||.   .  . .. . .
lseellsklgisyvlnasnscpkleelkeskflrvPvkDkydekllpwfdksvefidkaksengrvlvhvlaGisrsatvaiayimktlemsldeayrfv

RVHRPCVRPNEGFMRQLEEYETSIL
. .|| . ||  |. || ||| .. 
kekrptispnlnflgqLleyekelk
0042113 (Phosphotyrosine protein) phosphatases II 373-493 4.5e-22 74.1 In-house 65-239 (245) alignment 
Range on Protein: 373-493
Range on HMM: 65-239/245.0
VAYNLEILKYHNITHILNVAN-----------------------------------------------LNNVYPDHFTYKNLPIWDLPEVKITKFFKYAI
|.  .. |. ..||.|... .                                                .. .  ...|  ||. | ..  ... .  ..
vedfwrmlwelgittivmLteeeelgrvkcaqywplgesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldfl

DFINQARS--TGGRVLVHCNAGRSRSTTIVVGYIL-----ADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYE
.|...|..   .|.|||||.||..|. |... |..     .  .  . ....|.| .||.........|.| |..
efvrkalaedsngpvlVHCsaGvgRtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeal
0051429 (Phosphotyrosine protein) phosphatases II 376-496 2.2e-21 72.2 In-house 37-224 (272) alignment 
Range on Protein: 376-496
Range on HMM: 37-224/272.0
NLEILKYHNITHILNVANLN-------NVYPDHFTYKNLPIWDLPEVKITKFF-----------------------------------------------
... || ..|..|... ...         |. ...| .|||.|  .  |. ..                                               
dfwrlkelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvp

-KYAIDFINQARStGGRVLVHCNAGRSRSTTIVVGYILAdERAR--------------ISKTLEEIRVHRPCVRPNEGFMRQLEEYETSI
 .. ...... .. ||.|||||.||..|. |.|. ..|. ..                . ...||.| .||.....|.....| |..  .
qeallellellld.ggpvlvHCsaGkdRTGtvvalllll.lgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallel
0039614 (Phosphotyrosine protein) phosphatases II 377-494 9.1e-21 70.0 In-house 118-286 (297) alignment 
Range on Protein: 377-494
Range on HMM: 118-286/297.0
LEILKYHNITHILNVANLNN--------------------------VYPDHFTYKNLPI-----------------WDLPEVKITKFFKYAIDFINQARS
.. .. ...|.|... .|.                            . |..|. .|..                  |     ... .  .......|..
wrmvweqgvtvivmLtklvelgrkcaqywpeeggtygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvreala

---TGGRVLVHCNAGRSRSTTIVVGYIL-----ADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYET
    ||.|||||.|| .|. |... |..        .  . ....|.| .||.........|.| ... 
elpkggpvlVHCsaGvgRtGtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydall
0036941 (Phosphotyrosine protein) phosphatases II 382-494 6.2e-20 67.1 In-house 100-274 (297) alignment 
Range on Protein: 382-494
Range on HMM: 100-274/297.0
YHNITHILNVANLNNV--------------------------------YPDHFTYKNLPIWD----------------LPEVKITKFFKYAIDFINQARS
 .|.|.|... .|                                   . |..|. .| ..|                 |. ..   ... .|||...|.
eqnvtvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrk

------TGGRVLVHCNAGRSRSTTIVVGYIL--------ADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYET
       ||.|||||.|| .|| |... ...          ..  | ... ..| .||.. ......|.| |.. 
vlkllpsggpvlVHCsaGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeall
0043336 (Phosphotyrosine protein) phosphatases II 377-493 2.8e-18 61.8 In-house 105-273 (278) alignment 
Range on Protein: 377-493
Range on HMM: 105-273/278.0
LEILKYHNITHILNVANLN------------------------------------------------NVYPDHFTYKNLPIWDLPEvKITKFFKYAIDFI
 . .. ...|.|... .|                                                   .  |. |.. |  ..||  .. ....  ...
wrmvwelgvttivmLtelvelgrvkcaqYwpggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpe.slsllldflkavr

NQARSTGGRVLVHCNAGRSRSTTIVVGYIL-----ADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYE
.. .. .| |||||.|| .|. |... |.|        .  . ....|.| .||.  ... ..|.| |..
ealedsngpvlVHCsaGvgRTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyeal
subfamily_PTPMT1_pd Subfamily PTPMT1 405-497 3.9e-18 60.5 In-house 77-169 (171) alignment 
Range on Protein: 405-497
Range on HMM: 77-169/171.0
KNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYETSIL
 .|...|  |   ..  . ...||.. .|.| || |||.|||.||.|.|  |..  |.    . |. ..  |. .| ..  ...|.|||...|
lqlatvDfteapdleklekgvefiekvaskgkrvYvHCkaGrgRsatlvacylmkkeklspeeAlkalkkkRkiirlakkqwkalqeyeekll
0038934 (Phosphotyrosine protein) phosphatases II 382-495 3.7e-17 58.0 In-house 54-175 (194) alignment 
Range on Protein: 382-495
Range on HMM: 54-175/194.0
YHNITHILNV------ANLNNVYPDHFTYKNLPIWDL---PEVKITKFFKYAIDFINqARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEI
..........       . . ..   ..| .||. |    |  .|.. |  ..|... ....|| |.||| ||..|. |.|. |..   .    . .. .
nvklglvidltnteryYdpeefekagieylklpfpddgtvPsleillrfldlvdefl.nedpggvvaVHCkaGlgRtGtlvaaYLiyrlgmsaeeAialf

RVHRPCVRPNEGFMRQLEEYETS
|  || . || .....| ..   
rekRpgaipnqdyleallkryke
subfamily_STYXL1_pd Subfamily STYXL1 371-498 4.1e-17 55.8 In-house 30-155 (157) alignment 
Range on Protein: 371-498
Range on HMM: 30-155/157.0
CDVAYNLEILKYHNITHilNVANLNNVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLE
  . ..| .  . |...  .  .| .  .|     .... | .| .. ...| |..||.. . .|  |||  | | |||......|..  ..    |...
paikkdlkvkahvnvsm..dadkliagvadvakllhiavedeneadllerlkeavqfiekhkkegevvlvfsnkGisrsaaviiaylmyskkitlkkayk

EIRVHRPCVRPNEGFMRQLEEYETSILA
 ..  .. |.|| .|. ||.|.| ..| 
ylkkCkenvkPnrafveqlseWekqllg
0047943 (Phosphotyrosine protein) phosphatases II 389-489 5.7e-15 51.0 In-house 137-264 (273) alignment 
Range on Protein: 389-489
Range on HMM: 137-264/273.0
LNVANLNNVYPDHFTYKNLPIWD----------------LPEVKITKFFKYAIDFINQARS------TGGRVLVHCNAGRSRSTTIVVGYIL-----ADE
. | .|.  . |..|  .| ...                 |. ..   ... ..||...|.       .| |.|||.|| .|. |... ..|     .  
ftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsaGvgRtgtfialdllldqlekeg

RARISKTLEEIRVHRPCVRPNEGFMRQL
.  . ...  .| .||.. ... ..|.|
gvdvleavkllrsqRpgmvqtpeqyrfl
0051299 (Phosphotyrosine protein) phosphatases II 388-485 1.6e-13 46.2 In-house 148-274 (288) alignment 
Range on Protein: 388-485
Range on HMM: 148-274/288.0
ILNVANLNNVYPDHFTYKNLPIWDL--------------------PEVKITKFFKYAIDFINQARST----GGRVLVHCNAGRSRSTTIVVGYIL-----
 . | .|. .  |..|. .| . .|                    |.  .   ..  .||....|.     || |.|||.|| .|. |... ..|     
ditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkalasgggpvvVHCsaGvgRtgtfialdllleqle

ADERARISKTLEEIRVHRPCVRPNEGF
. ..  . .... .| .||.. ...  
keggvdvleavkrlreqRpgmvqtpeq
subfamily_Sponge-DSP-Subfam1_pd Subfamily Sponge-DSP-Subfam1 377-493 1.1e-12 41.3 In-house 17-138 (145) alignment 
Range on Protein: 377-493
Range on HMM: 17-138/145.0
LEILKYHNITHILNVANLN-----NVYPDHFTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEE
. .|.   |. |.|.|  .     ... ....   .   ||    ... |    |||.. .  |  |.||| || ||| |. | ...      .|..  .
vptlqelgisrivnmaagslvasqelksesieillitaedlesydlsqhfdevtdfidkgkeegagvfvhcmagvsrsvtvsvaflmkycnmtlseaarq

IRVHRPCVRPNEGFMRQLEEYE
.| .|    ||  |...| . |
vrsnrllaypnvtflknllnle
0050432 (Phosphotyrosine protein) phosphatases II 393-483 3.7e-12 41.7 In-house 172-285 (308) alignment 
Range on Protein: 393-483
Range on HMM: 172-285/308.0
NLNNVYPDHFTYKNLPIWD----------------LPEVKITKFFKYAIDFINQARST--GGRVLVHCNAGRSRSTTIVVGYIL-----ADERARISKTL
.|.    |..|. .| ...                 |. ..   ..  .||....|..  || ..|||.|| .|. |... ..|     .. .  . ...
llseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrkslpggpivVHCsaGvGRtGtfialdllleqlekeggvdvfeav

EEIRVHRPCVRPNE
  .| .||.. ...
kklReqRpgmvqtp
0046845 (Phosphotyrosine protein) phosphatases II 395-483 7.3e-12 40.7 In-house 163-260 (284) alignment 
Range on Protein: 395-483
Range on HMM: 163-260/284.0
NNVYPDHFTYKNLPIWDLPE-VKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADE--------RARISKTLEEIRVHRPCVRPNE
. ..  || |.. |  . |. ...   |  ... .......|| ..||| || .|. |... ..| .         .  . ...  .| .||.   ..
esrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGvgRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtl
subfamily_MSG5_pd Subfamily MSG5 414-497 2.7e-10 33.6 In-house 78-161 (165) alignment 
Range on Protein: 414-497
Range on HMM: 78-161/165.0
EVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYETSIL
. ||.| .      |  |.| . ..||||. | |||....| ||.      . .. . ..     . |. |.. || |.|. . 
dskivkdlsrltriihaatskrkkilvhcqcglsrsaslivayimkyynlslrdaydklksvaddispsiglifqlmewevals
PTPc_DSPc_SM00012 401-477 1.7e-08 29.9 In-house 4-87 (105) alignment 
Range on Protein: 401-477
Range on HMM: 4-87/105.0
HFTYKNLPIWDLPE--VKITKFFKYAIDFINQARStGGRVLVHCNAGRSRSTTIVVGYILADE------RARISKTLEEIRVHRP
|. |.. |   .||   .|......  .. |.. | .. |.||| || .|. |.|. .|| .       .  |.....|.| .||
hyhytgwpdhgvPeesdsilellravkknknkses.skpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRp
Y_phosphatase Protein-tyrosine phosphatase 372-477 1.6e-07 26.3 Pfam-A 113-217 (235) alignment 
Range on Protein: 372-477
Range on HMM: 113-217/235.0
DVAYNLEILKYHNITHILnvanLNNVYpDHFTYKNLPIWDLPEVkitkfFKYAIDFINQARSTG----GRVLVHCNAGRSRSTTIVVGYILADERAR---
. .|.|. |.... ..       ..    .. |.| | ...||       |  .|.|.. ...     | |.||| || .|. |.|.  || ..  .   
ekeytlrklelkkkkees....ekrev.kqlhytnWpdhgvpes.....pkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee

--ISKTLEEIRVHRP
  . ....|.| .||
vdvlqivkelRkqRp
Y_phosphatase Protein-tyrosine phosphatase 372-477 1.6e-07 26.3 In-house 113-217 (235) alignment 
Range on Protein: 372-477
Range on HMM: 113-217/235.0
DVAYNLEILKYHNITHILnvanLNNVYpDHFTYKNLPIWDLPEVkitkfFKYAIDFINQARSTG----GRVLVHCNAGRSRSTTIVVGYILADERAR---
. .|.|. |.... ..       ..    .. |.| | ...||       |  .|.|.. ...     | |.||| || .|. |.|.  || ..  .   
ekeytlrklelkkkkees....ekrev.kqlhytnWpdhgvpes.....pkslldlirkvekskeaksgpvvVhCsaGvgRtgtfvaldilleqleaeee

--ISKTLEEIRVHRP
  . ....|.| .||
vdvlqivkelRkqRp
subfamily_Laforin_pd Subfamily Laforin 402-479 1.8e-07 24.2 In-house 77-154 (183) alignment 
Range on Protein: 402-479
Range on HMM: 77-154/183.0
FTYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEIRVHRPCV
..|  ||. ||      . .  |. ..      | .| ||||||  |||.||.|..       ..|    .  .||.|
layiwlptedlstesrvenlpqavyllhallekghivyvhcnagvgrstaivcgflqyvlgwslakvqyfllakrpvv
subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 341-478 2.8e-07 24.8 In-house 117-258 (307) alignment 
Range on Protein: 341-478
Range on HMM: 117-258/307.0
VRLVKNRCHGPIPLSKAKQKIeeTGRQEASCDVAyNLEILKYHNITHILNVANLNNVYPDHF-TYKNLPIWDLPEVKITKFFKYAIDFINQARSTGGRVL
. | | .|.   || . ....   | .  .  || || . |     ...||..|. .. ..  | . |   . |.  . .    ||....  |     |.
ielakikceqywpleegqklv..fgeapntisva.nlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavrydtnpvv

VHCNAGRSRSTTIVVGYILADE------RARISKTLEEIRVHRPC
||| ||  || |||   .. |          . | .||.| .|. 
vhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhy
0048567 (Phosphotyrosine protein) phosphatases II 413-480 8.7e-07 23.4 In-house 52-122 (157) alignment 
Range on Protein: 413-480
Range on HMM: 52-122/157.0
PEVKITKFFKYAIDFINQARSTGGRVLVHCNAGR---SRSTTIVVGYILADERARISKTLEEIRVHRPCVR
.   ...|.... .|... . .|... ||| ||.   .|. |..  |..   .   ..... .|. ||   
nlailyrFilklnkflkilelagkaiavhckaglkkrgrtatLigcYlilhlgftpeeaiaplrivrpgsv
subfamily_PTPDC1_pd Subfamily PTPDC1 404-495 1.8e-06 22.5 In-house 85-174 (182) alignment 
Range on Protein: 404-495
Range on HMM: 85-174/182.0
YKNLPIWDLPEVKITKFFKyAIDFINQARSTGgRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEIRVHRPCVRPNEGFMRQLEEYETS
. |... |     ... .   .  ...| . | .| ||| ||. |   ..  |..  .|   .|... .| .||      . .. ..|... 
vynfgwkDygvasleriLd.ivkvvafalqeg.kvavhChaGlGrtGvliacylvyakrltaekaiklvrskrpksiqtreqvelvkefalf
subfamily_CDC14_pd Subfamily CDC14 426-478 3.6e-06 21.1 In-house 254-306 (328) alignment 
Range on Protein: 426-478
Range on HMM: 254-306/328.0
DFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEIRVHRPC
 |.. | .. | . ||| ||  |  |..  |.. . |   . ..  .|. || 
kfleiaekaeGaiavhCkaGLGrtGtLiacylmkhyrftaaeaiawlricrPG
subfamily_DSP23_pd Subfamily DSP23 425-479 4.2e-06 21.5 In-house 74-128 (148) alignment 
Range on Protein: 425-479
Range on HMM: 74-128/148.0
IDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADERARISKTLEEIRVHRPCV
.  ...| . .  | |||  || |. |..  |..  ..   .... |.|  ||  
vrvveeaeekneavsvhcllgrgrtgtmlacylvkerklaaaeaiaevrrlrpgs
DSPc_SM00195 397-479 6.3e-06 21.1 In-house 158-244 (263) alignment 
Range on Protein: 397-479
Range on HMM: 158-244/263.0
VYPDHFTYKNLPIWDLPEvKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADE-----RARISKTLEEIRVHRPCV
    .. ||| |  ..|. . ......   . .. ... | ..||| || .|. |.|.  |. ..     .  |.....|.| .|| .
rkvtqyqyknWpdhgvpd.stksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm
PTPc_SM00194 397-479 6.3e-06 21.1 In-house 158-244 (263) alignment 
Range on Protein: 397-479
Range on HMM: 158-244/263.0
VYPDHFTYKNLPIWDLPEvKITKFFKYAIDFINQARSTGGRVLVHCNAGRSRSTTIVVGYILADE-----RARISKTLEEIRVHRPCV
    .. ||| |  ..|. . ......   . .. ... | ..||| || .|. |.|.  |. ..     .  |.....|.| .|| .
rkvtqyqyknWpdhgvpd.stksvlellravkkskstssgpivVhCsaGvgRtgtfvtidiilskleeekkvdifeivkelRkqRpgm