Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRB_pd | Subfamily PTPRB | 83-188 | 2.1e-46 | 153.3 | In-house | 29-135 (293) | alignment | ||
Range on Protein: 83-188
Range on HMM: 29-135/293.0
LKAEKIKAM-MDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL
. |..||. .| .|....... | .. ... .|||||||||.|.|..|||||||||||||||||.|.|||||.||||.|||.||||.|||||||||
eeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltql
VEKGKVR
||||||.
vekgkvk
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 113-187 | 9.6e-34 | 111.9 | In-house | 57-131 (564) | alignment | ||
Range on Protein: 113-187
Range on HMM: 57-131/564.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. .||||.| .. |...|||||..| ||.......| ||||. |..| |||.||...|.|||||.|.|||||
ivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkv
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 106-186 | 6.3e-32 | 106.6 | In-house | 51-131 (288) | alignment | ||
Range on Protein: 106-186
Range on HMM: 51-131/288.0
AAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.. ..|||||| | .....|||||.||.|||..|.|.|.|||||.||.| |||.||.....|||||.|||.|.
eknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgr
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 95-187 | 2.6e-31 | 104.5 | In-house | 29-117 (273) | alignment | ||
Range on Protein: 95-187
Range on HMM: 29-117/273.0
IMKCDQHEEKPAAQCTGKVILNEHSRVKLaalaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
... ...| .. ..|||||| .|...|||||.|..|||..|.|.|.|||||.||.| |||.||.....|||||.|||.|..
tysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgre
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 96-186 | 2.8e-31 | 104.4 | In-house | 31-117 (297) | alignment | ||
Range on Protein: 96-186
Range on HMM: 31-117/297.0
MKCDQHEEKPAAQCTGKVILNEHSRVKLaalaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... . .| . .. ..|.|||| ||...|||||.|..||. .|.|.|.|||||.||.| |||.|| ....|||||.|||.|.
lsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgr
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 97-186 | 3.1e-31 | 104.3 | In-house | 61-147 (308) | alignment | ||
Range on Protein: 97-186
Range on HMM: 61-147/308.0
KCDQHEEKPAAQCTGKVILNEHSRVKLaaladDSDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.. ...| .. ..|||||| |...|||||.|..|| ..||.| |.|||||.||.| |||.|| ....|||||.|||.|.
svallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengr
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 93-186 | 3.5e-31 | 103.0 | In-house | 36-130 (563) | alignment | ||
Range on Protein: 93-186
Range on HMM: 36-130/563.0
DLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDT-DYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|| .. |..| . ... ..|||||. |.. .. |||||||| ||. ..|.| ||||. |.|| ||||||....||||.|.|||.|.
dldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergr
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 113-187 | 6.2e-31 | 102.6 | In-house | 55-129 (318) | alignment | ||
Range on Protein: 113-187
Range on HMM: 55-129/318.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. .|.|||| |... ..||||||||.||.. ....|.|.||| |..|.|||.||.....||||||..|.||.
ilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergka
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 93-186 | 8.9e-31 | 102.7 | In-house | 32-125 (317) | alignment | ||
Range on Protein: 93-186
Range on HMM: 32-125/317.0
DLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... ...| . .....|||||| | | |.|||||.|..|.| .|.| |.|||||.||.| |||.|| ....|||||.|.|.|.
ldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgr
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 111-187 | 2e-30 | 101.6 | In-house | 35-117 (284) | alignment | ||
Range on Protein: 111-187
Range on HMM: 35-117/284.0
GKVILNEHSRVKLAALADD-SDTDYINANYIPGY-----NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. ..|||||| | .| .|.|||||.|..|| .....|.|.|||||.||.| |||.||.....|||||.|||.|..
kdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengre
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 85-186 | 9.1e-30 | 99.5 | In-house | 26-127 (278) | alignment | ||
Range on Protein: 85-186
Range on HMM: 26-127/278.0
AEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
|.. . ... ...| . .....|||||| | | |.|||||.|..||| ||.| |.|||||.||.| |||.|| ....|||||.|||.
feellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvel
GK
|.
gr
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 95-188 | 1.2e-29 | 98.4 | In-house | 40-132 (319) | alignment | ||
Range on Protein: 95-188
Range on HMM: 40-132/319.0
IMKCDQHEEKPAAQCtGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
. .....| |. . .. ...||.|..| . ..|||||..| ||. ..|.| |.|| |..|.|||.||...||.||||.||||.||.
fdsaskeenkkknry.qnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvk
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 94-186 | 2.6e-29 | 98.4 | In-house | 45-146 (307) | alignment | ||
Range on Protein: 94-186
Range on HMM: 45-146/307.0
LIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADD-SDTDYINANYI--------PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
... ...| .....|.|||| | .. .|.|||||.|. .||...|.|.|.|||||.||.| |||.||.....|||||.|||.
geysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvel
GK
|.
gr
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 96-186 | 5.5e-29 | 97.0 | In-house | 48-140 (297) | alignment | ||
Range on Protein: 96-186
Range on HMM: 48-140/297.0
MKCDQHEEKPAAQCTGKVILNEHSRVKLAALAD-DSDTDYINANYIPGYNS-PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... ...| .. ..|||||| . . | |.|||||.|..||. .|.| |.|||||.||.| |||.|| ....|||||.|||.|.
ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr
|
|||||||||
DSPc_SM00195 | 106-186 | 1e-28 | 95.8 | In-house | 28-108 (263) | alignment | |||
Range on Protein: 106-186
Range on HMM: 28-108/263.0
AAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. . ......|.|||| .....|||||||| |.|..... |.||||| ||.| |||.||.|..||||||. .|.||
sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengk
|
|||||||||
PTPc_SM00194 | 106-186 | 1e-28 | 95.8 | In-house | 28-108 (263) | alignment | |||
Range on Protein: 106-186
Range on HMM: 28-108/263.0
AAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. . ......|.|||| .....|||||||| |.|..... |.||||| ||.| |||.||.|..||||||. .|.||
sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengk
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 113-188 | 2.8e-28 | 93.8 | In-house | 50-125 (281) | alignment | ||
Range on Protein: 113-188
Range on HMM: 50-125/281.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
.. ...|||.. ....|||||||..|||....|..|.|||.| .....|.|.||.| |.|||.|. .|.||..
ivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklk
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 83-186 | 1.9e-27 | 91.0 | In-house | 41-140 (330) | alignment | ||
Range on Protein: 83-186
Range on HMM: 41-140/330.0
LKAEKIKAMMDLIMKCDQHEEkpaaQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLV
| | .|.| ..| | . .| . ... ...||| |. . ..||||| .| ||. .|.|.|||. ||.|.||||||.|.. |||||.|
lPagpiqatlelaskeenkek....nrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelk
EKGK
|. .
erke
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 112-187 | 1.9e-27 | 91.1 | In-house | 50-125 (297) | alignment | ||
Range on Protein: 112-187
Range on HMM: 50-125/297.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
|. ...||.|| . .|. .||||||.. ||. .. |.| ||||. ||.| |||.||... .||| |..||.|..
dvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrl
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 98-186 | 4.5e-27 | 90.7 | In-house | 5-93 (249) | alignment | ||
Range on Protein: 98-186
Range on HMM: 5-93/249.0
CDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. ...| . . .. ..|||||| | . ..|||||.||.||...|.| |.|||||.||.| |||.|| . ..|||||.|||.|.
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgr
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 98-187 | 6.6e-27 | 89.9 | In-house | 3-92 (245) | alignment | ||
Range on Protein: 98-187
Range on HMM: 3-92/245.0
CDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
. ...| . . .....|.|||| | |.|||||.|..||. .. | |.|||||.||.| |||.|| . ..|||||...|.|.|
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrv
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 113-186 | 1.3e-26 | 88.3 | In-house | 58-131 (315) | alignment | ||
Range on Protein: 113-186
Range on HMM: 58-131/315.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.| ..|||.| | |...||.|||.|.||| .| ..|.|||.. .|.|.||...|.. . |||||.|||. |
iiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegek
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 100-187 | 2e-26 | 87.6 | In-house | 39-126 (314) | alignment | ||
Range on Protein: 100-187
Range on HMM: 39-126/314.0
QHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
...|. . . .|... ..|||.| .. .|...|||||..| .|. |..|.. ||||. || |.||........ |||||.|||.|.|
kkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrv
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 112-186 | 2.2e-26 | 88.1 | Pfam-A | 9-81 (235) | alignment | ||
Range on Protein: 112-186
Range on HMM: 9-81/235.0
KVILNEHSRVKLaalADDSD-TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... ...|||| .... .|||||||. ||.....|.|.||||. |..| |||.|..|...|||||.|.|||.
dilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgr
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 112-186 | 2.2e-26 | 88.1 | In-house | 9-81 (235) | alignment | ||
Range on Protein: 112-186
Range on HMM: 9-81/235.0
KVILNEHSRVKLaalADDSD-TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... ...|||| .... .|||||||. ||.....|.|.||||. |..| |||.|..|...|||||.|.|||.
dilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgr
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 117-187 | 9.5e-26 | 85.5 | In-house | 60-130 (288) | alignment | ||
Range on Protein: 117-187
Range on HMM: 60-130/288.0
EHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. |||| | . ...|||||.|| |... ....| ||||. ||.| |....|.||| |||||.|||.||
DekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggkt
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 97-186 | 2.2e-25 | 84.4 | In-house | 39-128 (305) | alignment | ||
Range on Protein: 97-186
Range on HMM: 39-128/305.0
KCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. ...|.. |.. . ...| ...|..|.. .. |.|||||.|. ||.. .... ||||. ||.| ||.|.| |.| |||||.||| ||
dvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggk
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 112-185 | 3.3e-25 | 84.5 | In-house | 41-102 (278) | alignment | ||
Range on Protein: 112-185
Range on HMM: 41-102/278.0
KVILNEHSRVKlaaladdsdtDYINANYIPGYnsPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
.. ..||||| |||||.||.|| |..| |.||||| ||.| |||.|| ....|||||.|||.|
dilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelg
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 111-186 | 6.2e-25 | 82.8 | In-house | 35-112 (274) | alignment | ||
Range on Protein: 111-186
Range on HMM: 35-112/274.0
GKVILNEHSRVKL-AALADDSDTDYINANYIPGYNS-PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... ||.||| | .. ..|.|..||||||| ||. . ..| ||||| ||.|.||||.......|||||.| |. .
ktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeane
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 111-188 | 8.5e-25 | 82.2 | In-house | 47-124 (290) | alignment | ||
Range on Protein: 111-188
Range on HMM: 47-124/290.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
.. ..|||.| .. . ||||||.| | ... |..| ||||| |.|| |||||||...|.||. ..|| || .
kDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkk
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 112-187 | 1.2e-24 | 82.1 | In-house | 64-139 (298) | alignment | ||
Range on Protein: 112-187
Range on HMM: 64-139/298.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..| ..||| | . .| ..||||| .. .|. |.|.|.||. || | |||..|.. . |||||.|.|..|.
diialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldkt
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 113-187 | 1.4e-24 | 81.5 | In-house | 29-104 (270) | alignment | ||
Range on Protein: 113-187
Range on HMM: 29-104/270.0
VILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. . ..||.|. | .|| | ||||||..|.. ......| .|||| |. . ||||||.|.. |||.|.|.|||.
iLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrk
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 107-186 | 3.2e-24 | 80.6 | In-house | 51-130 (307) | alignment | ||
Range on Protein: 107-186
Range on HMM: 51-130/307.0
AQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... .. ||||. . . |.|||||..| ||. ..|.| |.|. .|..| ||||.|.. .||||..| || .
knRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknr
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 110-180 | 3.4e-24 | 80.8 | In-house | 31-101 (284) | alignment | ||
Range on Protein: 110-180
Range on HMM: 31-101/284.0
TGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
|... ....||| | .||||| .| || .. ..|.||||. |..|.|||||| ..| ||.||.
ighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivlltk
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 111-180 | 4e-24 | 80.5 | In-house | 68-137 (319) | alignment | ||
Range on Protein: 111-180
Range on HMM: 68-137/319.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
.... ....||| | .||||| .. || .. ..|.||||. |..|.|||||| ..| ||.||.
inilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivlltk
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 112-187 | 5e-23 | 76.6 | In-house | 17-92 (250) | alignment | ||
Range on Protein: 112-187
Range on HMM: 17-92/250.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..| ..||| | | ..||||| .. ||. . |.| ||||. |. |.|||..|.|.. |||||.|.|..|.
diialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 112-187 | 6.4e-22 | 73.7 | In-house | 18-88 (243) | alignment | ||
Range on Protein: 112-187
Range on HMM: 18-88/243.0
KVILNEHSRVKLaaladdSDTDYINANYIPGYnsPReFMACQGPLPGTVDD----MWRMIWEKKTSIIVMLTQLVEKGKV
.....|||||| ...||||||.|... || . |.|||||.||.| |||.|| ....|||||.|||.|..
dilpydhsrvkl......egsdyinanliyvt..pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgre
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 116-187 | 1.2e-21 | 71.9 | In-house | 56-127 (315) | alignment | ||
Range on Protein: 116-187
Range on HMM: 56-127/315.0
NEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
...|||| . |. | ||||| ||..... . ..| ||||. .|||.|||....|.. |||.|.. | |.
ldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdki
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 116-187 | 2.5e-21 | 70.4 | In-house | 55-126 (515) | alignment | ||
Range on Protein: 116-187
Range on HMM: 55-126/515.0
NEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
. .|||| . |. . ||.|| |||.... . ..| |||.. .|||.||........ |.|.|.| | |.
ydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdki
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 110-187 | 9.8e-21 | 68.8 | In-house | 44-120 (287) | alignment | ||
Range on Protein: 110-187
Range on HMM: 44-120/287.0
TGKVILNEHSRVKLAALAdDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..|. ...|| |.| . . .|||||||...|. .|.|.|||.. || |.||...|.... ....|. ||...
yadvlPiddtrvllsaeg.elGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearl
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 99-188 | 1.4e-20 | 68.8 | In-house | 32-118 (273) | alignment | ||
Range on Protein: 99-188
Range on HMM: 32-118/273.0
DQHEEKPAAQCTGKVILNEHSRVKLAALADdsdtdYINANYIPG--YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
...|. .. .|. ...|||| . . ||||..| . |..||||||| ||.|.|.|.||.|...|.|.|. .|||||.
gkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 112-186 | 1.5e-20 | 68.3 | In-house | 55-128 (418) | alignment | ||
Range on Protein: 112-186
Range on HMM: 55-128/418.0
KVILNEHSRVKLAALADDSDTDYINANYIPGyNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... .|.||.| . | .|||||||| | |..|.. ||||| |. |.|||.||.. |||||.. |. .
nilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencr
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 112-186 | 1.8e-20 | 68.1 | In-house | 62-137 (306) | alignment | ||
Range on Protein: 112-186
Range on HMM: 62-137/306.0
KVILNEHSRVKLAaLADDSDTDYINANYIP--GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.. .|.||.|. . ...|||||||| .| ....| || |. || | |||.|.... .|||.|. ||.||
nilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgk
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 112-187 | 1.8e-20 | 68.0 | In-house | 54-131 (290) | alignment | ||
Range on Protein: 112-187
Range on HMM: 54-131/290.0
KVILNEHSRVKLAALADDSD--TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
...... |. | .... | .|||| || ||. ....| |||.. |. | |..||..|..||||||. .|.|||
nivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkv
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 116-185 | 3.7e-20 | 67.2 | In-house | 63-130 (297) | alignment | ||
Range on Protein: 116-185
Range on HMM: 63-130/297.0
NEHSRVKLAALADDSDTDYINANYIPGYNSprEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
. |||||| . || | ||.|| ...|.. .... | | . ||.|.|.|......|.||||... |.
ydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerd
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 118-187 | 3.9e-20 | 66.9 | In-house | 55-124 (280) | alignment | ||
Range on Protein: 118-187
Range on HMM: 55-124/280.0
HSRVKLaalaDDSDTDYINANYI----PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
. |||| ..|.||||||||. |. . ..|.||||. |. |.|.|.||.|.|.|||||.|||.|.|
atrvkl....kesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrv
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 109-186 | 4e-20 | 67.0 | In-house | 8-84 (237) | alignment | ||
Range on Protein: 109-186
Range on HMM: 8-84/237.0
CTGKVILNEHSRVKLAALAddSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|... .|||| | |..|||||.|. |.. .|....|.|||| . ||.|.|.|..| |.||||| |.|. .
rygnivaydhsrvvlkgag..sgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegne
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 112-185 | 4.1e-20 | 66.5 | In-house | 53-126 (392) | alignment | ||
Range on Protein: 112-185
Range on HMM: 53-126/392.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
... . .|||| . | .|.||.|| |||.... . ..|.||| . ..||.|||....... |.|.|.| |
nilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 90-187 | 2.4e-19 | 64.4 | In-house | 35-133 (300) | alignment | ||
Range on Protein: 90-187
Range on HMM: 35-133/300.0
AMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDsDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.| .... . .| . . .|. |..||.|.. .. .|.|||| | . |.....||||. || |.|.|.||.....|||||. |.||
kredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgke
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 112-183 | 2.4e-19 | 64.6 | In-house | 56-127 (325) | alignment | ||
Range on Protein: 112-183
Range on HMM: 56-127/325.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
|. ..||| | .. ||...|||||.|. . |.|.| ||. |..|.||.. . ..|..|.| .| .
nvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldl
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 90-185 | 2.7e-19 | 64.2 | In-house | 19-113 (283) | alignment | ||
Range on Protein: 90-185
Range on HMM: 19-113/283.0
AMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADdsdtDYINANYIP---GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
.. || ... .|.. . ... . ||.| ... ||||| .|| |. ......|.|| || |.|.|....| . |||||.| |
svpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedl
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 113-187 | 2.8e-18 | 60.6 | In-house | 41-111 (290) | alignment | ||
Range on Protein: 113-187
Range on HMM: 41-111/290.0
VILNEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
| .|||.|| ..|.|||||. . . |... ||||| ||| .|.|.||.|. .||| ..|||...
vspydhsrikle....radndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqi
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 112-185 | 3.4e-18 | 60.6 | In-house | 55-124 (287) | alignment | ||
Range on Protein: 112-185
Range on HMM: 55-124/287.0
KVILNEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
... . || | . . ||||| .| ||.. ..|.....|. |. ..|..|.... ..||||.|. |.
qilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekend
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 113-187 | 3.4e-18 | 60.5 | In-house | 52-123 (288) | alignment | ||
Range on Protein: 113-187
Range on HMM: 52-123/288.0
VILNEHSRVKLAaladDSDTDYINANYIPGYNS--PrEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. .|.|||| .| ||||| .. . . | .|.| |.||..|. | |.|..|.|.|.||||.. |.||
ilPyDhnRvklr....gskDDYinAsfvkdlspgcP.dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkp
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 119-186 | 4e-18 | 60.1 | In-house | 55-124 (301) | alignment | ||
Range on Protein: 119-186
Range on HMM: 55-124/301.0
SR--VKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
| .| | . ..||||.|| ||.. ..|.| |||. |. |.||.||..|.. |||.|.| |. |
nriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtk
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 110-183 | 4.7e-18 | 59.8 | In-house | 48-121 (296) | alignment | ||
Range on Protein: 110-183
Range on HMM: 48-121/296.0
TGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
||. .. || | | ....||||| |. .. ..|.. ..| |||. ||.......| .|.||. .
dvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfd
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 111-186 | 5.2e-18 | 60.1 | In-house | 15-91 (239) | alignment | ||
Range on Protein: 111-186
Range on HMM: 15-91/239.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... .|||| | |..| .|||||.|. |. ||. ..| || . . |.|||.|... .||||| |.| |
anivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghk
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 111-186 | 5.3e-18 | 60.0 | In-house | 14-90 (239) | alignment | ||
Range on Protein: 111-186
Range on HMM: 14-90/239.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... .|||| | |..| .|||||.|. |. ||. ..| || . . |.|||.|... .||||| |.| |
anivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghk
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 113-184 | 9.3e-18 | 58.9 | In-house | 57-128 (439) | alignment | ||
Range on Protein: 113-184
Range on HMM: 57-128/439.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
| .|.|| | . . ||||||| || .. ..|.||| |.||.||...||||. |||||.|||
vgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlves
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 113-186 | 3.4e-17 | 57.2 | In-house | 42-115 (297) | alignment | ||
Range on Protein: 113-186
Range on HMM: 42-115/297.0
VILNEHSRVKLAALAddSDTDYINANYI--PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.. . .|||| ...|||||.|. | ... .. |||| |||| |....|. .|||...| | |.
ilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGr
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 101-186 | 1.3e-16 | 55.1 | In-house | 53-139 (297) | alignment | ||
Range on Protein: 101-186
Range on HMM: 53-139/297.0
HEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYnSPRE--FMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.|. . . .|. .|||||| . |.....||||| | ||. ..|.||||. || |.|.|.||. . .||.||.| |.|
aeknvkknrskavlpydhsrvklkeeasaeksdyinasaildh.dprapayiatqgplastvadfwqmvweqGvvvivnltrleeegv
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 81-184 | 1.6e-16 | 56.4 | In-house | 23-154 (314) | alignment | ||
Range on Protein: 81-184
Range on HMM: 23-154/314.0
TVLKAEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEhSRVKLaALADDSDTDYINANYIPGYnspREFMACQGPLPGTVDDM----------WRMI--W
||. . .. .|... .... . . . ... . .||.| . |..|||||.|. |. . |.|.||||. ||.| |||. .
lvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrg
EKKTSIIVM---------------------LTQLVEK
. .. .||| |..| ..
dlnvrdivmsrdevladelsrLdaAlgKtpllildgn
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 112-186 | 1.8e-16 | 54.7 | In-house | 37-112 (319) | alignment | ||
Range on Protein: 112-186
Range on HMM: 37-112/319.0
KVILNeHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG-K
| | ..|| | .|| . |..|.|. ||. .| ..|.| .| . |.||..||... .|| ||.| |.| |
vvPlP.etrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGik
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 113-187 | 3.3e-16 | 53.8 | In-house | 65-134 (290) | alignment | ||
Range on Protein: 113-187
Range on HMM: 65-134/290.0
VILNEHSRVklaALADDSDTDYINANYIPGYNSPreFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
|. |. .|| | | | ||. |||. | ... |. ||.| || |.|||. ..|.. |||| .|.|.||
vvcndktrv...ilkdGydGdyvhanyvkGlkam..filtqGalkdtvidiwrmvlqekvaaivmlceliedGka
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 129-181 | 2.8e-15 | 51.9 | In-house | 2-54 (172) | alignment | ||
Range on Protein: 129-181
Range on HMM: 2-54/172.0
DSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL
|...|||||.|...| |..| |.||||. |..| |||..|.. ..||.||.|
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 113-179 | 3.9e-15 | 51.4 | In-house | 10-66 (182) | alignment | ||
Range on Protein: 113-179
Range on HMM: 10-66/182.0
VILNEHSRvklaaladdsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
.. ..||| | ||||||.. |. ...| |.||||..|| |..||..| . ..||.||
ilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 102-186 | 4.3e-15 | 50.5 | In-house | 48-121 (288) | alignment | ||
Range on Protein: 102-186
Range on HMM: 48-121/288.0
EEKPAAQCtgkvilnEHSRVKLAalaDDSDTdYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. | . .|||| ||.| ||.|| .. . .| .. .| || ||.. .|.|. |. ||||..|.||||
ryenlprc.......ditrvkls...ddpdf.yiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGk
|
|||||||||
subfamily_egg_pd | Subfamily egg | 112-184 | 4.4e-15 | 50.2 | In-house | 48-120 (307) | alignment | ||
Range on Protein: 112-184
Range on HMM: 48-120/307.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
.| .. ||||| |.| ||.. | ||. .| || ||||.|||..... ||||| .|
rvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 117-185 | 1.3e-14 | 48.5 | In-house | 50-119 (281) | alignment | ||
Range on Protein: 117-185
Range on HMM: 50-119/281.0
EHSRVKLAA-LADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
. |||.| . . |||| |||| | .. ||| | |.|||||...|. |||| |..|
disrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletn
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 116-185 | 1.2e-13 | 45.5 | In-house | 59-142 (350) | alignment | ||
Range on Protein: 116-185
Range on HMM: 59-142/350.0
NEHSRVKLA--------ALADDSDTDYINANYIPGY------NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
||||||| | |||||||. |. ..| |.||| ||||....| . | .|..||..|| .
YehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdveln
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 87-187 | 2.2e-13 | 44.5 | In-house | 35-134 (310) | alignment | ||
Range on Protein: 87-187
Range on HMM: 35-134/310.0
KIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAaLADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|. | | . . .... . |. . ||||| . ||| |||. |. .|||| |. |.||||..... |..| . .|.|.
kldakqdssltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegr
V
p
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 132-187 | 4.4e-13 | 45.0 | In-house | 4-61 (272) | alignment | ||
Range on Protein: 132-187
Range on HMM: 4-61/272.0
TDYINANYIPGYNS---PREFMACQGPLPGTVDDMWRMiWEKKTSIIVMLTQLVEKGKV
..||||....||.. |. . ...|||| |..| ||. .| . . ||.|....|.|..
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrl
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 124-187 | 1.3e-12 | 42.0 | In-house | 72-136 (305) | alignment | ||
Range on Protein: 124-187
Range on HMM: 72-136/305.0
AALADDSDTDYINANYIPGYNSP-REFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
|.. | .||| |||. | . |...|||| |.|..| |. ..| |||| . || ||.
vkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgkl
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 116-181 | 1.5e-12 | 42.1 | In-house | 45-106 (267) | alignment | ||
Range on Protein: 116-181
Range on HMM: 45-106/267.0
NEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL
...|| | ... .|||| |. ||. . |.. |.|| |. | . .| ..| ..||.||.
yddtrvilr....tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkv
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 127-187 | 3.1e-12 | 42.1 | In-house | 7-63 (176) | alignment | ||
Range on Protein: 127-187
Range on HMM: 7-63/176.0
ADDSDTDYINANYIPGYnsprEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.| | ||||||.| |. . |.|||||.|. | ..|..| . ...|.||..||.|..
gldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrl
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 114-186 | 3.6e-12 | 40.6 | In-house | 58-127 (305) | alignment | ||
Range on Protein: 114-186
Range on HMM: 58-127/305.0
ILNEHSRVKLaalADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.. |||| .|| |||. |. |. .| || | |.| | ...| | || .|.|||
gcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekga
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 115-188 | 4.8e-12 | 40.5 | In-house | 52-123 (307) | alignment | ||
Range on Protein: 115-188
Range on HMM: 52-123/307.0
LNEHSRVKLAalADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
...|. . | .||| |||. |. |...|||| |. ..| |. ..| ..|| ...| .|..
cqdkgrivvk..fdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakik
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 134-185 | 8.1e-12 | 39.5 | In-house | 77-128 (301) | alignment | ||
Range on Protein: 134-185
Range on HMM: 77-128/301.0
YINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
| ||.|| |. |.| ||||. | .|.| |. . ||||.| |||
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekl
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 132-185 | 9.6e-12 | 40.4 | In-house | 2-50 (174) | alignment | ||
Range on Protein: 132-185
Range on HMM: 2-50/174.0
TDYINANYIPGYNSPREFMACQGPLPgtvddMWRMIWEKKTSIIVMLTQLVEKG
.|||||... .. .... |.||||. |.|..| . ...|||....|.|
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelg
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 83-185 | 1.5e-11 | 38.8 | In-house | 14-113 (285) | alignment | ||
Range on Protein: 83-185
Range on HMM: 14-113/285.0
LKAEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLaalaDDSDTDYINANYI--PGYNSpREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
|. .||| | .| .| . | | .|| | . | ||| |... || . ... ||||| |. |.|.||...| . ..||
lhqdkikgymppnctytayeanpdlnryadvrcieetrvvl....knhdrdyihaswmrmpgkdq.styittqgplpetlsdfwhmiyqekiayvlmlct
LVEKG
|.| |
lfegg
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 139-186 | 3.1e-11 | 38.7 | In-house | 1-48 (152) | alignment | ||
Range on Protein: 139-186
Range on HMM: 1-48/152.0
YIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.|.||. |.||.|.|||.| |..| |||..| . ..|||||.|.|.||
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgk
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 112-177 | 3.3e-10 | 34.0 | In-house | 53-115 (347) | alignment | ||
Range on Protein: 112-177
Range on HMM: 53-115/347.0
KVILNeHSRVKlAALADDSDTdYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVM
.|.| . | . |||..| |||| .| |. .|.. | ||| || |.|.|. | . .|
rvvls.peksk.nsraddvet.yinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 130-183 | 9.2e-10 | 32.3 | In-house | 88-143 (349) | alignment | ||
Range on Protein: 130-183
Range on HMM: 88-143/349.0
SDTDYINANYI--PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
|||||||. . .. . ..| | ||| |||| ...| .. ... |.. |
klddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddke
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 80-182 | 2.7e-09 | 30.2 | In-house | 9-78 (169) | alignment | ||
Range on Protein: 80-182
Range on HMM: 9-78/169.0
KTVLKAEKIKAMMDLiMKCDQHEEKPAAQctgkvILNEHSRVKLAALADDSDTDYINAnyipgynsprefmacqgplpgtvddmwRMIWEKKTSIIVMLT
| ..|. . . .| . |.. ...||. . | |||| . .| .||||| ||||| .|.||.|
kefmktieynnfmae.ltcnetknrpagp.....lapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlg
QLV
.
dtd
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 80-182 | 3.5e-09 | 29.7 | In-house | 8-77 (169) | alignment | ||
Range on Protein: 80-182
Range on HMM: 8-77/169.0
KTVLKAEKIKAMMDLiMKCDQHEEKPAAQctgkvILNEHSRVKLAALADDSDTDYINAnyipgynsprefmacqgplpgtvddmwRMIWEKKTSIIVMLT
| ..|. . . .| . |.. ...||. . | |||| . .| .||||| ||||| .|.||.|
kefmktieynnfmae.ltcnetknrpagp.....lapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlG
QLV
.
dtd
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 115-186 | 5.9e-09 | 29.8 | In-house | 45-115 (332) | alignment | ||
Range on Protein: 115-186
Range on HMM: 45-115/332.0
LNEHSRVKLAAlaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDD-MWRMIWEKKTSIIVMLTQLVEKGK
.||||.|| .| |. ||... ||. .. .| |. . .|||. |.| |.|... .. || |
cfdhsrvelap..qdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqk
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 132-185 | 1.9e-08 | 29.6 | In-house | 3-47 (151) | alignment | ||
Range on Protein: 132-185
Range on HMM: 3-47/151.0
TDYINANYIPGYnspreFMACQGPLPgtvdDMWRMIWEKKTSIIVMLTQLVEKG
.||||..|. |. . ...|||. | .....| . . ||.|....| |
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 112-178 | 2.1e-08 | 28.2 | In-house | 55-114 (303) | alignment | ||
Range on Protein: 112-178
Range on HMM: 55-114/303.0
KVILNEHSRVKLaaladdSDTDYINANYIPgYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVML
|| .||.||| ||. || |.|. .| . . | ||. | |.|.|| |.| ...|
dvicldhskvkl......sdssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlll
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 142-184 | 2e-07 | 24.7 | In-house | 231-273 (440) | alignment | ||
Range on Protein: 142-184
Range on HMM: 231-273/440.0
GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
|| |.| | || || |.||.. . . | |.|| || .|
gyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 117-185 | 2.2e-07 | 26.2 | In-house | 3-62 (178) | alignment | ||
Range on Protein: 117-185
Range on HMM: 3-62/178.0
EHSRVKLAALADDSDTDYINANYIPGYnsprEFMACQGPlpgtvDDMWRMIWEKKTSIIVMLTQLVEKG
...||.| | . .|||||..| .. ......| | .....| . . ||.||. .| |
drtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelg
|
|||||||||
subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 113-183 | 5.7e-07 | 23.4 | In-house | 105-173 (244) | alignment | ||
Range on Protein: 113-183
Range on HMM: 105-173/244.0
VILNEHSRVKLAAlaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
. . .|| |. |||| .. |.. | || | |.|.|. |.. ..|.| . |
glpfdfnrvplsk..gsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 122-183 | 8.8e-07 | 23.3 | In-house | 11-64 (130) | alignment | ||
Range on Protein: 122-183
Range on HMM: 11-64/130.0
KlaaladdsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
. . .||||... . .|.. | || | |.|.|. |. ..|.| . |
q........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsvee
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 126-186 | 9e-07 | 22.9 | In-house | 62-121 (312) | alignment | ||
Range on Protein: 126-186
Range on HMM: 62-121/312.0
LADDSdTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|| | || ||.. | |...|||| |. .|.. .. |..|. .|| |
lagde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgs
|
|||||||||
Tn7_Tnp_TnsA_C | TnsA endonuclease C terminal | 115-171 | 8.8e-06 | 12.2 | Pfam-A | 36-74 (79) | alignment | ||
Range on Protein: 115-171
Range on HMM: 36-74/79.0
LNEHSRVKLAALADDSDTDYinanyipgynsprefmacQGPLPGTVDDMWRMIWEKK
|.... |||| .. |.|| . . ..|. ...|..|.
lkkngntslaallakldndy..................nlepgealdlirqliAtkr
|