Gene PTPRB-4 in Strongylocentrotus purpuratus

Gene expression:

Classification

Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.

Level Class Gene list Wiki page
Fold CC1
Superfamily CC1
Family PTP
Subfamily PTPRB
Protein sequence
ID Type Fasta BLAST phosphatome Note
SpurP070_AA protein Get Run
SpurP070_AA_80-187 phosphatase_domain Get Run
Domains
Summary
Details
Domain Domain Description Range Significance Score Source Profile Range (length) Alignment
subfamily_PTPRB_pd Subfamily PTPRB 83-188 2.1e-46 153.3 In-house 29-135 (293) alignment
Range on Protein: 83-188
Range on HMM: 29-135/293.0
LKAEKIKAM-MDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL
 . |..||. .|  .|....... | ..  ...  .|||||||||.|.|..|||||||||||||||||.|.|||||.||||.|||.||||.|||||||||
eeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqGPlpetvddfWrmvwekkssiivmltql

VEKGKVR
||||||.
vekgkvk

subfamily_PTPRD_pd Subfamily PTPRD 113-187 9.6e-34 111.9 In-house 57-131 (564) alignment
Range on Protein: 113-187
Range on HMM: 57-131/564.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..  .||||.| ..  |...|||||..| ||.......| ||||. |..| |||.||...|.|||||.|.|||||
ivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPlaetiedFWRmvweqnsstiVmltkleEkgkv

0051299 (Phosphotyrosine protein) phosphatases II 106-186 6.3e-32 106.6 In-house 51-131 (288) alignment
Range on Protein: 106-186
Range on HMM: 51-131/288.0
AAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
       .. ..||||||  | .....|||||.||.|||..|.|.|.|||||.||.| |||.||.....|||||.|||.|.
eknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlpntvedFWrmvweqnvrvIvmltklvelgr

0047943 (Phosphotyrosine protein) phosphatases II 95-187 2.6e-31 104.5 In-house 29-117 (273) alignment
Range on Protein: 95-187
Range on HMM: 29-117/273.0
IMKCDQHEEKPAAQCTGKVILNEHSRVKLaalaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
 ... ...|         .. ..||||||    .|...|||||.|..|||..|.|.|.|||||.||.| |||.||.....|||||.|||.|..
tysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqnvrviVmLtelvelgre

0036941 (Phosphotyrosine protein) phosphatases II 96-186 2.8e-31 104.4 In-house 31-117 (297) alignment
Range on Protein: 96-186
Range on HMM: 31-117/297.0
MKCDQHEEKPAAQCTGKVILNEHSRVKLaalaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... . .|    .    .. ..|.||||    ||...|||||.|..||. .|.|.|.|||||.||.| |||.|| ....|||||.|||.|.
lsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnvtvIvmltelvelgr

0050432 (Phosphotyrosine protein) phosphatases II 97-186 3.1e-31 104.3 In-house 61-147 (308) alignment
Range on Protein: 97-186
Range on HMM: 61-147/308.0
KCDQHEEKPAAQCTGKVILNEHSRVKLaaladDSDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.. ...|         .. ..||||||     |...|||||.|..||  ..||.| |.|||||.||.| |||.|| ....|||||.|||.|.
svallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFwrmvweqnvrvIvmLtklvengr

subfamily_PTPRG_pd Subfamily PTPRG 93-186 3.5e-31 103.0 In-house 36-130 (563) alignment
Range on Protein: 93-186
Range on HMM: 36-130/563.0
DLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDT-DYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|| ..  |..|      . ...  ..|||||. |..  .. |||||||| ||.  ..|.| ||||. |.|| ||||||....||||.|.|||.|.
dldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplkdtfddFWrmiWeqnvaiivmitnlvergr

subfamily_Anemone-PTP-6_pd Subfamily Anemone-PTP-6 113-187 6.2e-31 102.6 In-house 55-129 (318) alignment
Range on Protein: 113-187
Range on HMM: 55-129/318.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..  .|.||||  |... ..||||||||.||.. ....|.|.||| |..|.|||.||.....||||||..|.||.
ilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpetieDfWrmvWeqnsavivmltqeeergka

0040438 (Phosphotyrosine protein) phosphatases II 93-186 8.9e-31 102.7 In-house 32-125 (317) alignment
Range on Protein: 93-186
Range on HMM: 32-125/317.0
DLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
   ... ...| .       .....||||||  |  | |.|||||.|..|.| .|.| |.|||||.||.| |||.|| ....|||||.|.|.|.
ldtysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedFwrmvweqgvtvivmLteleelgr

0046845 (Phosphotyrosine protein) phosphatases II 111-187 2e-30 101.6 In-house 35-117 (284) alignment
Range on Protein: 111-187
Range on HMM: 35-117/284.0
GKVILNEHSRVKLAALADD-SDTDYINANYIPGY-----NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
  .. ..||||||  | .| .|.|||||.|..||     .....|.|.|||||.||.| |||.||.....|||||.|||.|..
kdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqnvrvIVmltelvengre

0043336 (Phosphotyrosine protein) phosphatases II 85-186 9.1e-30 99.5 In-house 26-127 (278) alignment
Range on Protein: 85-186
Range on HMM: 26-127/278.0
AEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
 |..  .    ... ...|      .  .....||||||  |  | |.|||||.|..||| ||.| |.|||||.||.| |||.|| ....|||||.|||.
feellsfkldtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedFwrmvwelgvttivmLtelvel

GK
|.
gr

subfamily_Anemone-PTP-5_pd Subfamily Anemone-PTP-5 95-188 1.2e-29 98.4 In-house 40-132 (319) alignment
Range on Protein: 95-188
Range on HMM: 40-132/319.0
IMKCDQHEEKPAAQCtGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
. .....| |.  .    ..  ...||.|..| .  ..|||||..| ||.  ..|.| |.||  |..|.|||.||...||.||||.||||.||.
fdsaskeenkkknry.qnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPlentiedfWrmvWeeessivvmltklveklkvk

0045450 (Phosphotyrosine protein) phosphatases II 94-186 2.6e-29 98.4 In-house 45-146 (307) alignment
Range on Protein: 94-186
Range on HMM: 45-146/307.0
LIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADD-SDTDYINANYI--------PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
  ... ...|         .....|.||||  | .. .|.|||||.|.        .||...|.|.|.|||||.||.| |||.||.....|||||.|||.
geysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgydlkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvel

GK
|.
gr

0039614 (Phosphotyrosine protein) phosphatases II 96-186 5.5e-29 97.0 In-house 48-140 (297) alignment
Range on Protein: 96-186
Range on HMM: 48-140/297.0
MKCDQHEEKPAAQCTGKVILNEHSRVKLAALAD-DSDTDYINANYIPGYNS-PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
... ...|         .. ..||||||  . . | |.|||||.|..||.  .|.| |.|||||.||.| |||.|| ....|||||.|||.|.
ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatqgPlpetvedFwrmvweqgvtvivmLtklvelgr

DSPc_SM00195 106-186 1e-28 95.8 In-house 28-108 (263) alignment
Range on Protein: 106-186
Range on HMM: 28-108/263.0
AAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. .   ......|.||||    .....|||||||| |.|..... |.||||| ||.| |||.||.|..||||||. .|.||
sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengk

PTPc_SM00194 106-186 1e-28 95.8 In-house 28-108 (263) alignment
Range on Protein: 106-186
Range on HMM: 28-108/263.0
AAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. .   ......|.||||    .....|||||||| |.|..... |.||||| ||.| |||.||.|..||||||. .|.||
sknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlteeeengk

subfamily_Choan-PTP-1_pd Subfamily Choan-PTP-1 113-188 2.8e-28 93.8 In-house 50-125 (281) alignment
Range on Protein: 113-188
Range on HMM: 50-125/281.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
..  ...|||..   ....|||||||..|||....|..|.|||.| .....|.|.||.| |.|||.|. .|.||..
ivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqkvsaivmvtreieagklk

subfamily_PTPRA_pd Subfamily PTPRA 83-186 1.9e-27 91.0 In-house 41-140 (330) alignment
Range on Protein: 83-186
Range on HMM: 41-140/330.0
LKAEKIKAMMDLIMKCDQHEEkpaaQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLV
| | .|.| ..|  | . .|     .   ... ...||| |. .    ..||||| .| ||.   .|.|.|||.  ||.|.||||||.|.. |||||.| 
lPagpiqatlelaskeenkek....nrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPkeetvedfwrmiweqksativmltelk

EKGK
|. .
erke

subfamily_PTPN9_pd Subfamily PTPN9 112-187 1.9e-27 91.1 In-house 50-125 (297) alignment
Range on Protein: 112-187
Range on HMM: 50-125/297.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
 |.  ...||.|| . .|. .||||||.. ||. .. |.| ||||. ||.| |||.||... .||| |..||.|..
dvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttrvvergrl

0040439 (Phosphotyrosine protein) phosphatases II 98-186 4.5e-27 90.7 In-house 5-93 (249) alignment
Range on Protein: 98-186
Range on HMM: 5-93/249.0
CDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. ...| .   .   .. ..||||||  | .  ..|||||.||.||...|.| |.|||||.||.| |||.|| . ..|||||.|||.|.
vallpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgr

0042113 (Phosphotyrosine protein) phosphatases II 98-187 6.6e-27 89.9 In-house 3-92 (245) alignment
Range on Protein: 98-187
Range on HMM: 3-92/245.0
CDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
. ...| .   .   .....|.||||     | |.|||||.|..||. .. | |.|||||.||.| |||.|| . ..|||||...|.|.|
vallpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrv

subfamily_Urchin-PTP-7_pd Subfamily Urchin-PTP-7 113-186 1.3e-26 88.3 In-house 58-131 (315) alignment
Range on Protein: 113-186
Range on HMM: 58-131/315.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.|  ..|||.|  |  |...||.|||.|.||| .| ..|.|||.. .|.|.||...|.. . |||||.|||. |
iiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnvasvkdfwrlvfeedigkivmltnlvegek

subfamily_PTPRK_pd Subfamily PTPRK 100-187 2e-26 87.6 In-house 39-126 (314) alignment
Range on Protein: 100-187
Range on HMM: 39-126/314.0
QHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
...|. . . .|...  ..|||.| .. .|...|||||..| .|. |..|.. ||||. || |.||........ |||||.|||.|.|
kkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlvydencasivmltelvevgrv

Y_phosphatase Protein-tyrosine phosphatase 112-186 2.2e-26 88.1 Pfam-A 9-81 (235) alignment
Range on Protein: 112-186
Range on HMM: 9-81/235.0
KVILNEHSRVKLaalADDSD-TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
...  ...||||    .... .|||||||. ||.....|.|.||||. |..| |||.|..|...|||||.|.|||.
dilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgr

Y_phosphatase Protein-tyrosine phosphatase 112-186 2.2e-26 88.1 In-house 9-81 (235) alignment
Range on Protein: 112-186
Range on HMM: 9-81/235.0
KVILNEHSRVKLaalADDSD-TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
...  ...||||    .... .|||||||. ||.....|.|.||||. |..| |||.|..|...|||||.|.|||.
dilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgr

subfamily_Urchin-PTPRB-like_pd Subfamily Urchin-PTPRB-like 117-187 9.5e-26 85.5 In-house 60-130 (288) alignment
Range on Protein: 117-187
Range on HMM: 60-130/288.0
EHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. ||||  | . ...|||||.|| |... ....| ||||. ||.| |....|.||| |||||.|||.|| 
DekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWelvyenktstivmltelveggkt

subfamily_Sponge-PTP8_pd Subfamily Sponge-PTP8 97-186 2.2e-25 84.4 In-house 39-128 (305) alignment
Range on Protein: 97-186
Range on HMM: 39-128/305.0
KCDQHEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
. ...|.. |.. . ...| ...|..|..  .. |.|||||.|. ||..  .... ||||. ||.| ||.|.| |.| |||||.||| ||
dvgkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlkntvadfWrliveekvstivmltklveggk

0045098 (Phosphotyrosine protein) phosphatases II 112-185 3.3e-25 84.5 In-house 41-102 (278) alignment
Range on Protein: 112-185
Range on HMM: 41-102/278.0
KVILNEHSRVKlaaladdsdtDYINANYIPGYnsPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
 .. ..|||||          |||||.||.||  |..| |.||||| ||.| |||.|| ....|||||.|||.|
dilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgitvivmltelvelg

subfamily_PTPN5_RR_pd Subfamily PTPN5_RR 111-186 6.2e-25 82.8 In-house 35-112 (274) alignment
Range on Protein: 111-186
Range on HMM: 35-112/274.0
GKVILNEHSRVKL-AALADDSDTDYINANYIPGYNS-PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
 ... ||.||| | .. ..|.|..||||||| ||.   . ..| ||||| ||.|.||||.......|||||.| |. .
ktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeane

subfamily_PTPN12_pd Subfamily PTPN12 111-188 8.5e-25 82.2 In-house 47-124 (290) alignment
Range on Protein: 111-188
Range on HMM: 47-124/290.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
  ..  ..|||.|    .. . ||||||.| | ... |..| ||||| |.|| |||||||...|.||. ..|| || .
kDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkk

subfamily_Anemone-PTP-2_pd Subfamily Anemone-PTP-2 112-187 1.2e-24 82.1 In-house 64-139 (298) alignment
Range on Protein: 112-187
Range on HMM: 64-139/298.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..|  ..||| | .  .| ..||||| .. .|.    |.|.|.||. || | |||..|.. . |||||.|.|..|.
diialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvteedigtiVmltnleeldkt

subfamily_Choan-PTP-2_pd Subfamily Choan-PTP-2 113-187 1.4e-24 81.5 In-house 29-104 (270) alignment
Range on Protein: 113-187
Range on HMM: 29-104/270.0
VILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
.. . ..||.|. | .|| | ||||||..|.. ......| .|||| |. . ||||||.|.. |||.|.|.|||. 
iLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrk

subfamily_Ptp69D_pd Subfamily Ptp69D 107-186 3.2e-24 80.6 In-house 51-130 (307) alignment
Range on Protein: 107-186
Range on HMM: 51-130/307.0
AQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
     ...  .. ||||. .  . |.|||||..| ||.  ..|.| |.|. .|..| ||||.|..  .||||..| || .
knRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPveatigDfWRmiaeqevtlivmlsnlteknr

subfamily_Urchin-PTP-8_pd Subfamily Urchin-PTP-8 110-180 3.4e-24 80.8 In-house 31-101 (284) alignment
Range on Protein: 110-180
Range on HMM: 31-101/284.0
TGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
 |...  ....|||  |     .||||| .| || ..  ..|.||||. |..|.|||||| ..| ||.||.
ighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivlltk

subfamily_Urchin-PTPRA_pd Subfamily Urchin-PTPRA 111-180 4e-24 80.5 In-house 68-137 (319) alignment
Range on Protein: 111-180
Range on HMM: 68-137/319.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
....  ....|||  |     .||||| .. || ..  ..|.||||. |..|.|||||| ..| ||.||.
inilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivlltk

subfamily_Nvec-PTP-2_pd Subfamily Nvec-PTP-2 112-187 5e-23 76.6 In-house 17-92 (250) alignment
Range on Protein: 112-187
Range on HMM: 17-92/250.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..|  ..||| |     | ..||||| .. ||.  . |.| ||||. |. |.|||..|.|.. |||||.|.|..|.
diialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt

0037934 (Phosphotyrosine protein) phosphatases II 112-187 6.4e-22 73.7 In-house 18-88 (243) alignment
Range on Protein: 112-187
Range on HMM: 18-88/243.0
KVILNEHSRVKLaaladdSDTDYINANYIPGYnsPReFMACQGPLPGTVDD----MWRMIWEKKTSIIVMLTQLVEKGKV
 .....||||||      ...||||||.|...  || . |.|||||.||.|     |||.|| ....|||||.|||.|..
dilpydhsrvkl......egsdyinanliyvt..pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgre

subfamily_Urchin-PTP-1_pd Subfamily Urchin-PTP-1 116-187 1.2e-21 71.9 In-house 56-127 (315) alignment
Range on Protein: 116-187
Range on HMM: 56-127/315.0
NEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
 ...||||  . |. | ||||| ||..... . ..| ||||. .|||.|||....|.. |||.|.. |  |.
ldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvtkkqegdki

subfamily_Urchin-PTP-6_pd Subfamily Urchin-PTP-6 116-187 2.5e-21 70.4 In-house 55-126 (515) alignment
Range on Protein: 116-187
Range on HMM: 55-126/515.0
NEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
 . .||||  . |. . ||.|| |||.... . ..| |||.. .|||.||........ |.|.|.| |  |.
ydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdki

subfamily_Choan-PTP-3_pd Subfamily Choan-PTP-3 110-187 9.8e-21 68.8 In-house 44-120 (287) alignment
Range on Protein: 110-187
Range on HMM: 44-120/287.0
TGKVILNEHSRVKLAALAdDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
 ..|.  ...|| |.| . .  .|||||||...|.   .|.|.|||.. || |.||...|.... ....|. ||... 
yadvlPiddtrvllsaeg.elGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearl

subfamily_PTPN13_pd Subfamily PTPN13 99-188 1.4e-20 68.8 In-house 32-118 (273) alignment
Range on Protein: 99-188
Range on HMM: 32-118/273.0
DQHEEKPAAQCTGKVILNEHSRVKLAALADdsdtdYINANYIPG--YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
 ...|. ..    .|.  ...|||| . .      ||||..|     .   |..||||||| ||.|.|.|.||.|...|.|.|. .|||||.
gkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamvtlekekgkvk

subfamily_ptpA1_pd Subfamily ptpA1 112-186 1.5e-20 68.3 In-house 55-128 (418) alignment
Range on Protein: 112-186
Range on HMM: 55-128/418.0
KVILNEHSRVKLAALADDSDTDYINANYIPGyNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
...  .|.||.|  . |   .|||||||| |   |..|.. ||||| |. |.|||.||..  |||||..  |. .
nilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencr

subfamily_PTPN6_pd Subfamily PTPN6 112-186 1.8e-20 68.1 In-house 62-137 (306) alignment
Range on Protein: 112-186
Range on HMM: 62-137/306.0
KVILNEHSRVKLAaLADDSDTDYINANYIP--GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
 ..  .|.||.|.   . ...||||||||     .| ....| || |. || | |||.|.... .|||.|. ||.||
nilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrvivmttkevErgk

subfamily_Sponge-PTP11_pd Subfamily Sponge-PTP11 112-187 1.8e-20 68.0 In-house 54-131 (290) alignment
Range on Protein: 112-187
Range on HMM: 54-131/290.0
KVILNEHSRVKLAALADDSD--TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
......  |. |  .... |   .|||| || ||.  ....| |||.. |. | |..||..|..||||||. .|.|||
nivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsntlvdFWkliwqekvtiivmltniieegkv

subfamily_Urchin-PTP-5_pd Subfamily Urchin-PTP-5 116-185 3.7e-20 67.2 In-house 63-130 (297) alignment
Range on Protein: 116-185
Range on HMM: 63-130/297.0
NEHSRVKLAALADDSDTDYINANYIPGYNSprEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
 . |||||| . || | ||.|| ...|..   .... | | . ||.|.|.|......|.||||... |. 
ydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmkatvadfWamvldeqvstivmlnddnerd

subfamily_PTPN3_pd Subfamily PTPN3 118-187 3.9e-20 66.9 In-house 55-124 (280) alignment
Range on Protein: 118-187
Range on HMM: 55-124/280.0
HSRVKLaalaDDSDTDYINANYI----PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
. ||||    ..|.||||||||.    |. .    ..|.||||. |. |.|.|.||.|.|.|||||.|||.|.|
atrvkl....kesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivmlttlverGrv

subfamily_Anemone-PTP-4_pd Subfamily Anemone-PTP-4 109-186 4e-20 67.0 In-house 8-84 (237) alignment
Range on Protein: 109-186
Range on HMM: 8-84/237.0
CTGKVILNEHSRVKLAALAddSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
  |...  .|||| |      |..|||||.|. |.. .|....|.||||  . ||.|.|.|..| |.||||| |.|. .
rygnivaydhsrvvlkgag..sgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegne

subfamily_Urchin-PTP-4_pd Subfamily Urchin-PTP-4 112-185 4.1e-20 66.5 In-house 53-126 (392) alignment
Range on Protein: 112-185
Range on HMM: 53-126/392.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
...  . .||||  . | .|.||.|| |||.... . ..|.||| . ..||.|||....... |.|.|.| |  
nilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvtklkegd

subfamily_PTPN14_pd Subfamily PTPN14 90-187 2.4e-19 64.4 In-house 35-133 (300) alignment
Range on Protein: 90-187
Range on HMM: 35-133/300.0
AMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADDsDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
  .| .... . .|    . . .|.  |..||.|..  .. .|.||||  |      . |.....||||. || |.|.|.||.....|||||.  |.|| 
kredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivmlteeeedgke





subfamily_Urchin-PTP-3_pd Subfamily Urchin-PTP-3 112-183 2.4e-19 64.6 In-house 56-127 (325) alignment
Range on Protein: 112-183
Range on HMM: 56-127/325.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
 |.  ..||| | .. ||...|||||.|.  .     |.|.| ||. |..|.||.. . ..|..|.| .| .
nvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrlvldWrcsvvvvlneldl

subfamily_Sponge-PTP5_pd Subfamily Sponge-PTP5 90-185 2.7e-19 64.2 In-house 19-113 (283) alignment
Range on Protein: 90-185
Range on HMM: 19-113/283.0
AMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAALADdsdtDYINANYIP---GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
.. ||  ...  .|..  .   ...  .  ||.| ...     ||||| .||    |.  ......|.||  || |.|.|....| . |||||.| |  
svpdldadiasadenkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivmltklqedl

subfamily_PTPN1_pd Subfamily PTPN1 113-187 2.8e-18 60.6 In-house 41-111 (290) alignment
Range on Protein: 113-187
Range on HMM: 41-111/290.0
VILNEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
|   .|||.||     ..|.|||||. .   .  |...  ||||| ||| .|.|.||.|.  .||| ..|||...
vspydhsrikle....radndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvmlnkvvekeqi

subfamily_Sponge-PTP10_pd Subfamily Sponge-PTP10 112-185 3.4e-18 60.6 In-house 55-124 (287) alignment
Range on Protein: 112-185
Range on HMM: 55-124/287.0
KVILNEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
...  .  || |     . . ||||| .| ||.. ..|.....|.  |. ..|..|.... ..||||.|. |. 
qilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddrnvtaivmlcqekend

subfamily_PTPN23_pd Subfamily PTPN23 113-187 3.4e-18 60.5 In-house 52-123 (288) alignment
Range on Protein: 113-187
Range on HMM: 52-123/288.0
VILNEHSRVKLAaladDSDTDYINANYIPGYNS--PrEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
..  .|.||||     .|  ||||| .. .  .  | .|.| |.||..|. | |.|..|.|.|.||||..  |.|| 
ilPyDhnRvklr....gskDDYinAsfvkdlspgcP.dfiatqaPlqstlnDFWlmvyeqkssviVmllskeelgkp

subfamily_Sponge-PTP9_pd Subfamily Sponge-PTP9 119-186 4e-18 60.1 In-house 55-124 (301) alignment
Range on Protein: 119-186
Range on HMM: 55-124/301.0
SR--VKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
 |  .|     | . ..||||.|| ||.. ..|.| |||.  |. |.||.||..|.. |||.|.| |. |
nriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsivmvtnlkegtk

subfamily_CG7180_pd Subfamily CG7180 110-183 4.7e-18 59.8 In-house 48-121 (296) alignment
Range on Protein: 110-183
Range on HMM: 48-121/296.0
TGKVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
  ||.  .. || |  |  ....||||| |. ..  ..|..  ..|   |||. ||.......| .|.||.  .
dvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfd

subfamily_Anemone-PTP-1_pd Subfamily Anemone-PTP-1 111-186 5.2e-18 60.1 In-house 15-91 (239) alignment
Range on Protein: 111-186
Range on HMM: 15-91/239.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
 ...  .|||| |  |..|  .|||||.|.  |. ||. ..| || .  .  |.|||.|...  .||||| |.|  |
anivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghk

subfamily_Nvec-PTP-1_pd Subfamily Nvec-PTP-1 111-186 5.3e-18 60.0 In-house 14-90 (239) alignment
Range on Protein: 111-186
Range on HMM: 14-90/239.0
GKVILNEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
 ...  .|||| |  |..|  .|||||.|.  |. ||. ..| || .  .  |.|||.|...  .||||| |.|  |
anivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghk

subfamily_Sponge-PTP6_pd Subfamily Sponge-PTP6 113-184 9.3e-18 58.9 In-house 57-128 (439) alignment
Range on Protein: 113-184
Range on HMM: 57-128/439.0
VILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
|   .|.|| |  .     . ||||||| ||  .. ..|.|||   |.||.||...||||. |||||.||| 
vgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettddfwrlviekktvtivmltnlves

subfamily_Choan-PTP-4_pd Subfamily Choan-PTP-4 113-186 3.4e-17 57.2 In-house 42-115 (297) alignment
Range on Protein: 113-186
Range on HMM: 42-115/297.0
VILNEHSRVKLAALAddSDTDYINANYI--PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
..  . .||||      ...|||||.|.  |  ...  ..  ||||  |||| |....|.   .|||...| | |.
ilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGr

subfamily_PTPRN_pd Subfamily PTPRN 101-186 1.3e-16 55.1 In-house 53-139 (297) alignment
Range on Protein: 101-186
Range on HMM: 53-139/297.0
HEEKPAAQCTGKVILNEHSRVKLAALADDSDTDYINANYIPGYnSPRE--FMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.|.    . . .|.  .|||||| . |.....|||||  |     ||.  ..|.||||. || |.|.|.||. . .||.||.| |.| 
aeknvkknrskavlpydhsrvklkeeasaeksdyinasaildh.dprapayiatqgplastvadfwqmvweqGvvvivnltrleeegv

0049772 (Phosphotyrosine protein) phosphatases II 81-184 1.6e-16 56.4 In-house 23-154 (314) alignment
Range on Protein: 81-184
Range on HMM: 23-154/314.0
TVLKAEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEhSRVKLaALADDSDTDYINANYIPGYnspREFMACQGPLPGTVDDM----------WRMI--W
 ||.   . .. .|...  .... .  . . ...  . .||.|    . |..|||||.|. |.   . |.|.||||. ||.|           |||.  .
lvlnrrslsvlpeltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrg

EKKTSIIVM---------------------LTQLVEK
. .. .|||                     |..| ..
dlnvrdivmsrdevladelsrLdaAlgKtpllildgn

subfamily_CG42327_pd Subfamily CG42327 112-186 1.8e-16 54.7 In-house 37-112 (319) alignment
Range on Protein: 112-186
Range on HMM: 37-112/319.0
KVILNeHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG-K
 | |  ..|| |   .||  . |..|.|. ||. .|  ..|.| .|  .  |.||..||... .|| ||.| |.| |
vvPlP.etrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGik

subfamily_Cele-PTP-20_pd Subfamily Cele-PTP-20 113-187 3.3e-16 53.8 In-house 65-134 (290) alignment
Range on Protein: 113-187
Range on HMM: 65-134/290.0
VILNEHSRVklaALADDSDTDYINANYIPGYNSPreFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
|. |. .||    | |  | ||. |||. | ...  |.  ||.|  || |.|||. ..|.. |||| .|.|.|| 
vvcndktrv...ilkdGydGdyvhanyvkGlkam..filtqGalkdtvidiwrmvlqekvaaivmlceliedGka

0043147 (Phosphotyrosine protein) phosphatases II 129-181 2.8e-15 51.9 In-house 2-54 (172) alignment
Range on Protein: 129-181
Range on HMM: 2-54/172.0
DSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL
|...|||||.|...|  |..| |.||||. |..| |||..|.. ..||.||.|
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel

0041856 (Phosphotyrosine protein) phosphatases II 113-179 3.9e-15 51.4 In-house 10-66 (182) alignment
Range on Protein: 113-179
Range on HMM: 10-66/182.0
VILNEHSRvklaaladdsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
.. ..|||          | ||||||.. |.  ...| |.||||..|| |..||..| . ..||.||
ilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt

subfamily_Cele-PTP-8_pd Subfamily Cele-PTP-8 102-186 4.3e-15 50.5 In-house 48-121 (288) alignment
Range on Protein: 102-186
Range on HMM: 48-121/288.0
EEKPAAQCtgkvilnEHSRVKLAalaDDSDTdYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
  .    |       . .||||    ||.|  ||.|| ..  . .| .. .| || ||.. .|.|. |.    ||||..|.||||
ryenlprc.......ditrvkls...ddpdf.yiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGk

subfamily_egg_pd Subfamily egg 112-184 4.4e-15 50.2 In-house 48-120 (307) alignment
Range on Protein: 112-184
Range on HMM: 48-120/307.0
KVILNEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
.|  .. |||||         |.| ||.. |     ||. .| ||  ||||.|||.....   |||||  .| 
rvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes

subfamily_Cele-PTP-13_pd Subfamily Cele-PTP-13 117-185 1.3e-14 48.5 In-house 50-119 (281) alignment
Range on Protein: 117-185
Range on HMM: 50-119/281.0
EHSRVKLAA-LADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
. |||.|   . .   |||| ||||      | ..  |||   |  |.|||||...|. |||| |..|  
disrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletn

subfamily_Fungi-PTP1_pd Subfamily Fungi-PTP1 116-185 1.2e-13 45.5 In-house 59-142 (350) alignment
Range on Protein: 116-185
Range on HMM: 59-142/350.0
NEHSRVKLA--------ALADDSDTDYINANYIPGY------NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
 |||||||              |  |||||||.         |.   ..| |.||| ||||....| . |  .|..||..|| .
YehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvilsltsdveln

subfamily_Cele-PTP-14_pd Subfamily Cele-PTP-14 87-187 2.2e-13 44.5 In-house 35-134 (310) alignment
Range on Protein: 87-187
Range on HMM: 35-134/310.0
KIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLAaLADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|. |  |  .  . ....   .    |.  . |||||  .      ||| |||.        |. .||||  |. |.||||.....  |..| . .|.|.
kldakqdssltyeaykkymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegr

V
 
p

0051429 (Phosphotyrosine protein) phosphatases II 132-187 4.4e-13 45.0 In-house 4-61 (272) alignment
Range on Protein: 132-187
Range on HMM: 4-61/272.0
TDYINANYIPGYNS---PREFMACQGPLPGTVDDMWRMiWEKKTSIIVMLTQLVEKGKV
..||||....||..   |. . ...|||| |..| ||. .| . . ||.|....|.|..
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrl

subfamily_Cele-PTP-10_pd Subfamily Cele-PTP-10 124-187 1.3e-12 42.0 In-house 72-136 (305) alignment
Range on Protein: 124-187
Range on HMM: 72-136/305.0
AALADDSDTDYINANYIPGYNSP-REFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
  |.. | .||| |||.     | . |...||||  |.|..| |. ..|   |||| . || ||.
vkldkpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgkl

subfamily_Sponge-PTP1_pd Subfamily Sponge-PTP1 116-181 1.5e-12 42.1 In-house 45-106 (267) alignment
Range on Protein: 116-181
Range on HMM: 45-106/267.0
NEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQL
 ...|| |     ... .|||| |. ||.  . |.. |.||  |. | . .| ..| ..||.||. 
yddtrvilr....tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvpvivlltkv

0046846 (Phosphotyrosine protein) phosphatases II 127-187 3.1e-12 42.1 In-house 7-63 (176) alignment
Range on Protein: 127-187
Range on HMM: 7-63/176.0
ADDSDTDYINANYIPGYnsprEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKV
 .| | ||||||.| |.     . |.|||||.|. | ..|..| . ...|.||..||.|..
gldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrl

subfamily_Cele-PTP-18_pd Subfamily Cele-PTP-18 114-186 3.6e-12 40.6 In-house 58-127 (305) alignment
Range on Protein: 114-186
Range on HMM: 58-127/305.0
ILNEHSRVKLaalADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
   .. ||||         .|| |||.     |. |. .| ||  |  |.| | ...|   | || .|.||| 
gcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekga

subfamily_Cele-PTP-6_pd Subfamily Cele-PTP-6 115-188 4.8e-12 40.5 In-house 52-123 (307) alignment
Range on Protein: 115-188
Range on HMM: 52-123/307.0
LNEHSRVKLAalADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKVR
  ...|. .    |   .||| |||.     |. |...||||  |. ..| |. ..|   ..|| ...| .|..
cqdkgrivvk..fdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvielakik

subfamily_Cele-PTP-19_pd Subfamily Cele-PTP-19 134-185 8.1e-12 39.5 In-house 77-128 (301) alignment
Range on Protein: 134-185
Range on HMM: 77-128/301.0
YINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKG
 | ||.||    |. |.| ||||. | .|.| |.   .   ||||.| ||| 
PihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekl

0036282 (Phosphotyrosine protein) phosphatases II 132-185 9.6e-12 40.4 In-house 2-50 (174) alignment
Range on Protein: 132-185
Range on HMM: 2-50/174.0
TDYINANYIPGYNSPREFMACQGPLPgtvddMWRMIWEKKTSIIVMLTQLVEKG
.|||||... ..  .... |.||||.      |.|..| . ...|||....|.|
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelg

subfamily_Cele-PTP-15_pd Subfamily Cele-PTP-15 83-185 1.5e-11 38.8 In-house 14-113 (285) alignment
Range on Protein: 83-185
Range on HMM: 14-113/285.0
LKAEKIKAMMDLIMKCDQHEEKPAAQCTGKVILNEHSRVKLaalaDDSDTDYINANYI--PGYNSpREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
|. .|||  |        .| .|  .    |   | .|| |     . | ||| |...  || .    ... ||||| |. |.|.||...| . ..||  
lhqdkikgymppnctytayeanpdlnryadvrcieetrvvl....knhdrdyihaswmrmpgkdq.styittqgplpetlsdfwhmiyqekiayvlmlct

LVEKG
|.| |
lfegg

0049260 (Phosphotyrosine protein) phosphatases II 139-186 3.1e-11 38.7 In-house 1-48 (152) alignment
Range on Protein: 139-186
Range on HMM: 1-48/152.0
YIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
.|.||. |.||.|.|||.| |..| |||..| . ..|||||.|.|.||
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgk

subfamily_Cele-PTP-17_pd Subfamily Cele-PTP-17 112-177 3.3e-10 34.0 In-house 53-115 (347) alignment
Range on Protein: 112-177
Range on HMM: 53-115/347.0
KVILNeHSRVKlAALADDSDTdYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVM
.|.|    . |  . |||..| |||| .|   |. .|..  | ||| || |.|.|.   | . .| 
rvvls.peksk.nsraddvet.yinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvt

subfamily_Fungi-PTP2_pd Subfamily Fungi-PTP2 130-183 9.2e-10 32.3 In-house 88-143 (349) alignment
Range on Protein: 130-183
Range on HMM: 88-143/349.0
SDTDYINANYI--PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
   |||||||.  . ..  . ..| | ||| |||| ...|  ..  ... |..  |
klddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklvlsLnddke

subfamily_Sponge-PTP-2_pd Subfamily Sponge-PTP-2 80-182 2.7e-09 30.2 In-house 9-78 (169) alignment
Range on Protein: 80-182
Range on HMM: 9-78/169.0
KTVLKAEKIKAMMDLiMKCDQHEEKPAAQctgkvILNEHSRVKLAALADDSDTDYINAnyipgynsprefmacqgplpgtvddmwRMIWEKKTSIIVMLT
| ..|. . . .|   . |.. ...||.      .   | ||||  . .|  .|||||                           |||||  .|.||.| 
kefmktieynnfmae.ltcnetknrpagp.....lapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlg

QLV
.  
dtd

subfamily_Sponge-PTP2_pd Subfamily Sponge-PTP2 80-182 3.5e-09 29.7 In-house 8-77 (169) alignment
Range on Protein: 80-182
Range on HMM: 8-77/169.0
KTVLKAEKIKAMMDLiMKCDQHEEKPAAQctgkvILNEHSRVKLAALADDSDTDYINAnyipgynsprefmacqgplpgtvddmwRMIWEKKTSIIVMLT
| ..|. . . .|   . |.. ...||.      .   | ||||  . .|  .|||||                           |||||  .|.||.| 
kefmktieynnfmae.ltcnetknrpagp.....lapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlG

QLV
.  
dtd

subfamily_Cele-PTP-12_pd Subfamily Cele-PTP-12 115-186 5.9e-09 29.8 In-house 45-115 (332) alignment
Range on Protein: 115-186
Range on HMM: 45-115/332.0
LNEHSRVKLAAlaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDD-MWRMIWEKKTSIIVMLTQLVEKGK
  .||||.||   .|   |. ||... ||.    .. .| |.    .  .|||. |.| |.|... .. || |
cfdhsrvelap..qdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqk

0051082 (Phosphotyrosine protein) phosphatases II 132-185 1.9e-08 29.6 In-house 3-47 (151) alignment
Range on Protein: 132-185
Range on HMM: 3-47/151.0
TDYINANYIPGYnspreFMACQGPLPgtvdDMWRMIWEKKTSIIVMLTQLVEKG
.||||..|. |.     . ...|||.    | .....| . . ||.|....| |
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg

subfamily_Cele-PTP-16_pd Subfamily Cele-PTP-16 112-178 2.1e-08 28.2 In-house 55-114 (303) alignment
Range on Protein: 112-178
Range on HMM: 55-114/303.0
KVILNEHSRVKLaaladdSDTDYINANYIPgYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVML
 ||  .||.|||      ||. || |.|.   .| .  .  | ||. |  |.|.|| |.|   ...|
dvicldhskvkl......sdssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlll

subfamily_Urchin-PTP-2_pd Subfamily Urchin-PTP-2 142-184 2e-07 24.7 In-house 231-273 (440) alignment
Range on Protein: 142-184
Range on HMM: 231-273/440.0
GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEK
||     |.| | ||  || |.||.. . . | |.|| || .|
gyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk

0044763 (Phosphotyrosine protein) phosphatases II 117-185 2.2e-07 26.2 In-house 3-62 (178) alignment
Range on Protein: 117-185
Range on HMM: 3-62/178.0
EHSRVKLAALADDSDTDYINANYIPGYnsprEFMACQGPlpgtvDDMWRMIWEKKTSIIVMLTQLVEKG
...||.|  | .   .|||||..| ..     ......|      | .....| . . ||.||. .| |
drtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelg

subfamily_Sponge-PTP4_pd Subfamily Sponge-PTP4 113-183 5.7e-07 23.4 In-house 105-173 (244) alignment
Range on Protein: 113-183
Range on HMM: 105-173/244.0
VILNEHSRVKLAAlaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
 .  . .|| |.         |||| ..       |..  | ||  |  |.|.|. |..  ..|.|  . |
glpfdfnrvplsk..gsmgntyinasfvgclgrtaeyiltqhpladtsmdfwkmmlerhvnvlvvlgsvee

subfamily_Sponge-PTP-4_pd Subfamily Sponge-PTP-4 122-183 8.8e-07 23.3 In-house 11-64 (130) alignment
Range on Protein: 122-183
Range on HMM: 11-64/130.0
KlaaladdsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVE
.        . .||||...   .  .|..  | ||  |  |.|.|. |.   ..|.|  . |
q........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsvee

subfamily_Cele-PTP-11_pd Subfamily Cele-PTP-11 126-186 9e-07 22.9 In-house 62-121 (312) alignment
Range on Protein: 126-186
Range on HMM: 62-121/312.0
LADDSdTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGK
|| |    || ||..     |  |...||||  |.  .|..     .. |..|. .|| | 
lagde.nfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillcgfvedgs

Tn7_Tnp_TnsA_C TnsA endonuclease C terminal 115-171 8.8e-06 12.2 Pfam-A 36-74 (79) alignment
Range on Protein: 115-171
Range on HMM: 36-74/79.0
LNEHSRVKLAALADDSDTDYinanyipgynsprefmacQGPLPGTVDDMWRMIWEKK
|....   |||| .. |.||                  . .   ..|. ...|..|.
lkkngntslaallakldndy..................nlepgealdlirqliAtkr