Gene expression:
Classification
Phosphatases were first clustered by sequence similarity in the phosphatase domain, and additional information from domains outside of the catalytic domain, from evolutionary conservation, and from known functions was added. The result is a hybrid classification, in which no criterion is universally satisfied, but aims to be of practical use to a range of phosphatase interests. The classification grows as new phosphatomes are sequenced.
Protein sequence
Domains
Summary
Details
Domain | Domain Description | Range | Significance | Score | Source | Profile Range (length) | Alignment | ||
---|---|---|---|---|---|---|---|---|---|
subfamily_PTPRB_pd | Subfamily PTPRB | 493-719 | 2.9e-122 | 402.3 | In-house | 2-228 (293) | alignment | ||
Range on Protein: 493-719
Range on HMM: 2-228/293.0
SHSKPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQG
..||||.|.|||.|. .||||||.||.|||.|...||||||...| ..|||||||.||||||.|||||||||.|.|..|||||||||||||||||.|.||
kkskpiklekfeehvkkmkadsdlrfseeyeelkavgkdqavkaaelavnraknrytnilpydhsrvkLaalkdesgsDYinanyipgynsprefiatqG
PLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTM
|||.||||.|||.||||.||||||||||||||.||.||||||..||.||.|.|...| .....|||||..|....|.||..||||.|||||||||||.|.
PlpetvddfWrmvwekkssiivmltqlvekgkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktl
LDFVRTVREAIQKTASDRPIVAHCSAG
|||||||||||.||||.||||.|||||
ldfvrtvreaiektaskrPivvhCsaG
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 495-719 | 5.2e-87 | 287.8 | In-house | 2-224 (564) | alignment | ||
Range on Protein: 495-719
Range on HMM: 2-224/564.0
SKPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVgKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPL
|||| .... |. ..||.||..|.||| .|. . . .| . .|.||||. ||..|.||||.| .. |...|||||..| ||.......| ||||
skpipvaelkehvaklkansdlkfeeeykkieeg.qqftweaankpaNkaKNRyanivaYdhsRVvLskvegdegsDYINAsfidgyrkrkayIAtqgPl
PGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTM
. |..| |||.||...|.|||||.|.|||| |||.|||.. .. |||...|.... ... . .||.|... . .| |. .|.||.|||||||||.. ..
aetiedFWRmvweqnsstiVmltkleEkgkvkchkYWPek.gtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatsl
LDFVRTVREAIQktASDRPIVAHCSAG
||..|.||.. . ||| |||||
Ldlirkvralne..pdagPivVhCSaG
|
|||||||||
subfamily_PTPRB_pd | Subfamily PTPRB | 719-879 | 9.3e-86 | 282.5 | In-house | 132-292 (293) | alignment | ||
Range on Protein: 719-879
Range on HMM: 132-292/293.0
GAIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVGR
| .||.||||||..||.||.|.|...| .....|||||..|....|.||..||||.||||||||.||.|.|||||||||||.||||.||||.||||||||
gkvkCeeYWPadeepvlyGdikvtlvaeeeledwvirelkiekekeerkvrqyhftsWpdhgvPektktlldfvrtvreaiektaskrPivvhCsaGvGR
TGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEED
|||.||||||.||..|.||.|||||..|.|..||..|||||||||||.||.||||..|||.
tGtfialdrllqaieeedyvdifgivaelReeRnllvqtekqYifihqcvldllrkkeeek
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 498-719 | 6.3e-77 | 253.7 | In-house | 2-223 (318) | alignment | ||
Range on Protein: 498-719
Range on HMM: 2-223/318.0
IVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGT
| ....| | |.... . ..|||... . . . . .|| ||.||||..|||.|.|.|||| |... ..||||||||.||.. ....|.|.||| |
isvedleshvrrlresGelllseeyerlsrseetvtslkslepvnkaknryanilaydhtrvkLqmlegeegsDyinanyidGyrrkkayiaaqaPlpet
VDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDF
..|.|||.||.....||||||..|.||.|.| ||| . .. .||...| .. .....|.|||.... .| |. |||. ||||.||||.. ..||.
ieDfWrmvWeqnsavivmltqeeergkakvhryWPsk.gsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldl
VRTVREAiQKTASDRPIVAHCSAG
||.|..| |.... .||| |||||
vrqvska.qqksgagpivvhCsaG
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 496-719 | 1.3e-75 | 249.8 | In-house | 3-229 (288) | alignment | ||
Range on Protein: 496-719
Range on HMM: 3-229/288.0
KPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLP
..| ..... .. ...|.. .. ||..|.. . | . .|| |. |||...||||.|||||| | .....|||||.||.|||..|.|.|.|||||
teisveellklvlkllangltglleefeellsllpdltlsaallpenleknRysdilpydhsRVkLsvldgvegsdYinAsyidgynlkrkfIatqgPlp
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAdYNPVTYGSIQVSVQALQQYDHWVIREFSIS------QGDEIRKLTQYHFMSWPDHGVPEKT
.||.| |||.||.....|||||.|||.|..||. ||| ...||| |.| ...|....|.. .. ...| |. |..|...|||||||. .
ntvedFWrmvweqnvrvIvmltklvelgrekcaqYwpl.ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdsp
WTMLDFVRTVREAIQktASDRPIVAHCSAG
.|||.| ||.|.. ... |.| |||||
ellldflrlvrkala..sgggpvvVHCsaG
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 505-719 | 1.5e-72 | 239.9 | In-house | 31-242 (308) | alignment | ||
Range on Protein: 505-719
Range on HMM: 31-242/308.0
GHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLaaladDSDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMW
.. .||.. .. ||. |.. | . . .|| |. |||...||||.|||||| |...|||||.|..|| ..||.| |.|||||.||.| |
llkllekaldlglleeefeellsvkplleysvallpenkdkNrykdilpydhsRVkl.....degsdYInAsyvdgyssklprkfIatqgPlpntvedFw
RMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAD--YNPVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRT
||.|| ....|||||.|||.|..||..||| . ....|| ..| . ...|....|.. .. ..| |..|..|...|||||||... .|||..
rmvweqnvrvIvmLtklvengrekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflel
VREAIqktaSDRPIVAHCSAG
||. . .. ||| |||||
vrksl....pggpivVHCsaG
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 518-719 | 2.3e-71 | 235.8 | In-house | 2-214 (284) | alignment | ||
Range on Protein: 518-719
Range on HMM: 2-214/284.0
FTEEYDEIRLVGKDQ--AIVSALEMVNRAKNRFTNILPYEHSRVKLAALADD-SDTDYINANYIPGY-----NSPREFMACQGPLPGTVDDMWRMIWEKK
. ||. |.. . .. . || |. |||...||||.|||||| | .| .|.|||||.|..|| .....|.|.|||||.||.| |||.||..
leeefeellsltvklllslsvallpenlsknRykdilpydhsRVklksldgdledsdYinAsyvdgydldltyikkkfIatqgPlpntvedFwrmvweqn
TSIIVMLTQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKT
...|||||.|||.|..||. ||| . ...||| ..| . ...|....|..... ..| |..|..|..||||||||. . .|.|.|.|||.....
vrvIVmltelvengrekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenl
ASDRPIVAHCSAG
.. ||| |||||
pgggpivVHCsaG
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 510-719 | 3.6e-71 | 235.2 | In-house | 6-215 (273) | alignment | ||
Range on Protein: 510-719
Range on HMM: 6-215/273.0
MKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLaalaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKK
.|... .. ||..... . .. . || |. |||...||||.|||||| .|...|||||.|..|||..|.|.|.|||||.||.| |||.||..
ekllgltllleefelllslkplltysvallpenkdknrykdilpydhsrvkl....gdggsdyinAsyvdgynlkrkfiatqgPlpntvedfwrmvweqn
TSIIVMLTQLVEKGKIKCHEYWPADYN--PVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQK
...|||||.|||.|..||. ||| . . ..||| ..| . ...|....|.. .. .| |. |..|...|||||||. . .|.|.. ||.|...
vrviVmLtelvelgrekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalea
TASDRPIVAHCSAG
. |. |.| |||||
lpsngpvvVHCsaG
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 496-720 | 8.1e-71 | 233.7 | In-house | 3-227 (319) | alignment | ||
Range on Protein: 496-720
Range on HMM: 3-227/319.0
KPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDqAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLP
..| ..... .. .... .. . .|. ... ..| . || . |. |||..|||.|...||.|..| . ..|||||..| ||. ..|.| |.||
teievqeLkerlkalastgetllekefkllkeavnd.tfdsaskeenkkknryqnilaydrtrvvlseldgvegsdyinasfidgyqerekfiatqaPle
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQ-GDEI--RKLTQYHFMSWPDHGVPEKTWTM
|..|.|||.||...||.||||.||||.|.|...||| |...|| . | .. .. ....||.... . .|. |.........||||.||||. ..
ntiedfWrmvWeeessivvmltklveklkvklkkywpee.nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatsl
LDFVRTVREAIQKTaSDRPIVAHCSAGA
||... .|.. .|| ...||| |||||.
ldllkrirksrekt.qsgPivvhCsaGv
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 494-719 | 9.1e-71 | 234.0 | In-house | 10-232 (297) | alignment | ||
Range on Protein: 494-719
Range on HMM: 10-232/297.0
HSKPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDqaIVSALEMVNRAKNRFTNILPYEHSRVKLAALAD-DSDTDYINANYIPGYNS-PREFMACQ
| || |. .. .....||.| .. .|. |. . | .. || .|. |||...||||.|||||| . . | |.|||||.|..||. .|.| |.|
esipiplsvldlllllekansktllllefeellslkpd..ysiallpenkdknrykdilpydhsrvklkpedgvdldsdYinAsyvdgydlltrkfIatq
GPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKiKCHEYWPADYNpvTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWT
||||.||.| |||.|| ....|||||.|||.|. ||..||| . . ||| ..| . ...|....|..... ..| |..|......|||||||. . .
gPlpetvedFwrmvweqgvtvivmLtklvelgr.kcaqywpeegg..tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslel
MLDFVRTVREAIQKTASDRPIVAHCSAG
.|.|.. ||||.... ...|.. |||||
lleflelvrealaelpkggpvlVHCsaG
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 505-719 | 4.9e-70 | 230.8 | In-house | 10-222 (288) | alignment | ||
Range on Protein: 505-719
Range on HMM: 10-222/288.0
GHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRM
. ...|.. |.|||. . ..|... . . || |||. |||||.. |||| | . ...|||||.|| |... ....| ||||. ||.| |..
akvakksarnrtgfseeynsLaalektksvtagrlavnakknRyrnilpyDekrvklkkleeeagaDYinasyidgekkkkkyiatqgPladtvndfWel
IWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQ
..|.||| |||||.|||.|| ||.||||.. .|. |||..| .. .. ...| |.. . . . ...|||....|||||||| . .|...|.| | |
vyenktstivmltelveggktkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanq
KTasDRPIVAHCSAG
. ||. |||||
ad..tgpiivhCsaG
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 510-719 | 1.6e-69 | 229.1 | In-house | 9-218 (281) | alignment | ||
Range on Protein: 510-719
Range on HMM: 9-218/281.0
MKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKK
...... |.|||.... .| |.. ... . |. |||..|| |...|||.. ....|||||||..|||....|..|.|||.| .....|.|.||.|
lsqndnaGfieeyeklaaigvdntataskadenvlknrYsnivaYDatrvkvtpneenkntDYinanfvpgykgekeyiatqgPvPaslvafWqmvweqk
TSIIVMLTQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSI-SQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiQKTAS
|.|||.|. .|.||.||| ||| | . ..|| ..|. .| .. ... |.|.. .. | |...| ....|||||||..| .|.| . |... ... .
vsaivmvtreieagklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkl.tekkt
DRPIVAHCSAG
. |.| |||||
kaplvihCsaG
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 502-719 | 8.7e-69 | 227.5 | In-house | 4-219 (317) | alignment | ||
Range on Protein: 502-719
Range on HMM: 4-219/317.0
KFEGHYGRMKADSDFRFTEEYDEIRLVGKDqAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDM
... .. .... . .. ||. ... . .| . |. .|. |||...||||.|||||| | | |.|||||.|..|.| .|.| |.|||||.||.|
dlllalldllksdftalleefedllslkld.tysvaelpenkdknrypdilpydhsRVkLsplggdldsdYInAsyvdgpnlkrkfIatqgPlpntvedF
WRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAdYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTV
|||.|| ....|||||.|.|.|..||..||| ...||| ..| .. ........|.. .. ...| |..|..|...|||||||. . ..|||.. |
wrmvweqgvtvivmLteleelgrekcaqYwpl.getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleav
REAIQktASDRPIVAHCSAG
|||.. .. |.. |||||
reale..dpggpvlVHCsaG
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 511-719 | 9.9e-69 | 227.2 | In-house | 8-217 (297) | alignment | ||
Range on Protein: 511-719
Range on HMM: 8-217/297.0
KADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLaalaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKT
|... .. .|..|. . .. . || |. |||...||||.|.|||| ||...|||||.|..||. .|.|.|.|||||.||.| |||.|| ..
kllflalllkefeellpllllgslsvallpenleknRykdilpydhtRVkl....ddegsdYinAsyvdgydlkrkfIatqgPlpntvedFWrmvweqnv
SIIVMLTQLVEKGKIKCHEYWPAD-YNPVTYGSIQVSVQALQQ--YDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQK
..|||||.|||.|..||..||| . ...||| ..| .. .. .|....|.. .. ..| |..|..|...|||||||| . ..|||.. ||.....
tvIvmltelvelgrekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkl
TASDRPIVAHCSAG
. |. |.. |||||
lpsggpvlVHCsaG
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 494-719 | 2.1e-68 | 226.7 | In-house | 5-244 (307) | alignment | ||
Range on Protein: 494-719
Range on HMM: 5-244/307.0
HSKPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGK--DQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADD-SDTDYINANYI--------PGYN
.|..| . |.. .. ....|. .. .|. ... | . . .|| .|. |||...||||.|.|||| | .. .|.|||||.|. .||.
lslfidalkllllvllllldfltgllkefekllsvtvfllgeysiallpenkdknrykdilpydhtRVklssldgsledsdYiNAsyvrvpllllldgyd
SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSIS---QGDEIRKLTQYHFMS
..|.|.|.|||||.||.| |||.||.....|||||.|||.|..||..||| . ..||| ..| . ...|....| . .. . .| |..|..|. .
lkrkfIatqgPlpetvedFwrmlweqgvtvivmltelvelgrekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytg
WPDHGVPEKTWTMLDFVRTVREAIQKTASDRPIVAHCSAG
|||||||. . ..|||.. ||.|.... .. |.. |||||
wpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaG
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 502-719 | 2.8e-67 | 222.4 | In-house | 6-220 (278) | alignment | ||
Range on Protein: 502-719
Range on HMM: 6-220/278.0
KFEGHYGRMKADSDFRFTEEYDEIRLVGKdQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDM
... .. ...... .. .|. |.. . . . || . |. |||...||||.|||||| | | |.|||||.|..||| ||.| |.|||||.||.|
dllkallelllnlktllllefeellsfkl.dtysiallpenkdknrykdilpydhsrvklsllggdldsdYinAsyvdgynvprkfiatqgPlpetvedF
WRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPadYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTV
|||.|| ....|||||.|||.|..||..||| ...||| ..| .. ...|....| . .. . .| |. |.||...|||||||| . ..|||...|
wrmvwelgvttivmLtelvelgrvkcaqYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkav
REAIQktASDRPIVAHCSAG
|||.. |. |.. |||||
reale..dsngpvlVHCsaG
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 499-722 | 8.5e-67 | 220.6 | In-house | 2-233 (563) | alignment | ||
Range on Protein: 499-722
Range on HMM: 2-233/563.0
VLNKFEGHYGRMKADSDFRFTEEYDEIRL--VGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDT-DYINANYIPGYNSPREFMACQGPLP
...|. | ..||.| .|.||.... . || . .. . |. ||| .||..|..|||||. |.. .. |||||||| ||. ..|.| ||||.
pvkefakhvaslhadgdigfseefealqsetiskdldaehsqkpenkrKnRylnivaydrsRvklsplpgkkkklDYinAnyidGyqkskafiatqgplk
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAdYNPVTYGSIQVSVQALQQYD-----HWVIREFSISQGDE---IRKLTQYHFMSWPDHGVPE
|.|| ||||||....||||.|.|||.|. ||. |||. ...|||..|| .. .. . ||... . .... .. .|||. .||||||||
dtfddFWrmiWeqnvaiivmitnlvergrrkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPe
KTWTMLDFVRTVREAiqKTASDRPIVAHCSAGAIK
.. | ||. | . | ||| |||||. .
hslpvLifvkkssaa..nkaeaGPivvHcsaGvgr
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 495-720 | 1.4e-65 | 216.4 | In-house | 11-239 (330) | alignment | ||
Range on Protein: 495-720
Range on HMM: 11-239/330.0
SKPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPL
|. ..|.| . .|| .| ||.. . . .. | . |. |||. |||||..||| |. . ..||||| .| ||. .|.|.|||.
yfplpvekleeeirirsaddnklfreefnalPagpiqatlelaskeenkeknrvvnilPydfsrvilsvkeGveesdyinasfidGykekdkfiaaqGPk
PGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSIS-QGDE-----IRKLTQYHFMSWPDHGVPEK
||.|.||||||.|.. |||||.| |. . ||. ||| . |||| |.|.|. . .. .|.| . ..|. | ..|.|| |||| ||| .
eetvedfwrmiweqksativmltelkerkeekcaqywPde.GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfe
TWTMLDFVRTVREAIQKTASdrPIVAHCSAGA
. ||.... |.. |..|. ||| |||||.
piGmlkllkkvkklnqqsag..pivvhcsaGv
|
|||||||||
DSPc_SM00195 | 518-719 | 1.6e-63 | 209.8 | In-house | 2-205 (263) | alignment | |||
Range on Protein: 518-719
Range on HMM: 2-205/263.0
FTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
. ||..... ... . .| . |..|||..|||||.|.|||| .....|||||||| |.|..... |.||||| ||.| |||.||.|..||||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
QLVEKGKIKCHEYWPADY-NPVTYGSIQVSVQALQQYD-HWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTasDRPIV
. .|.||.||..||| . .. |.|.|.| .. .... ....|...... . | ||.|||.. .|||||||..| .|...|.|.. ... . |||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpiv
AHCSAG
|||||
VhCsaG
|
|||||||||
PTPc_SM00194 | 518-719 | 1.6e-63 | 209.8 | In-house | 2-205 (263) | alignment | |||
Range on Protein: 518-719
Range on HMM: 2-205/263.0
FTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
. ||..... ... . .| . |..|||..|||||.|.|||| .....|||||||| |.|..... |.||||| ||.| |||.||.|..||||||
lkeefekleestspketteaekkknksknRyknilpydhtrVklkkeekkegsdYINAnyikgankkkkyIatQgPlpstvedFWrmvweekvkiivmlt
QLVEKGKIKCHEYWPADY-NPVTYGSIQVSVQALQQYD-HWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTasDRPIV
. .|.||.||..||| . .. |.|.|.| .. .... ....|...... . | ||.|||.. .|||||||..| .|...|.|.. ... . |||
eeeengkekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpiv
AHCSAG
|||||
VhCsaG
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 496-720 | 9.4e-63 | 207.0 | In-house | 4-223 (315) | alignment | ||
Range on Protein: 496-720
Range on HMM: 4-223/315.0
KPIVLNKFEGHYGRMKADSDFRFTEEYDEIRlVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLP
.|| |... . . || . | ..|. | |. . . | .. |. |||. ||..|..|||.| | |...||.|||.|.||| .| ..|.|||..
qpipldqlityvaqkkastkngfkqdyesip.ggqlhpldvakkienkqknryiniiaydksrvqlpllendphsdyvnanfidGynkkrryiaaqgpnv
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADynPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDF
.|.|.||...|.. . |||||.|||. | |. .||| . |.|| | |. . ...... .| .|. ||.||.. |.|. |||| |||. | .....
asvkdfwrlvfeedigkivmltnlvegekrkaekywpdk..kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnl
VRTVREaiQKTASDRPIVAHCSAGA
.|||. .|.| .|| |||||
irtvkq..hhtnsvgaivvhcsaGv
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 535-719 | 5.7e-62 | 204.2 | In-house | 33-217 (290) | alignment | ||
Range on Protein: 535-719
Range on HMM: 33-217/290.0
VSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAD
.. ...|..|||. .||||..|||.| .. . ||||||.| | ... |..| ||||| |.|| |||||||...|.||. ..|| ||.||. |||
eagekeenvkknrykDilPydksrvelskieeeegsdYinanfikgvegkleyiaaqgPLpktlddfWrmiweknveivvmaCrevelgkkkCerYWpee
-YNPVTYGSIQVSVQALQQYD-HWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQktASDRPIVAHCSAG
.....|...|.... .. | ..|| . . . .| ||..|.|...|||||||... ..|.....||| . ..| |.| |||||
geeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..sedaPlvvhCsaG
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 539-719 | 1.1e-61 | 203.9 | In-house | 8-189 (249) | alignment | ||
Range on Protein: 539-719
Range on HMM: 8-189/249.0
EMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAdYNPV
..|. |||...||||.|||||| | . ..|||||.||.||...|.| |.|||||.||.| |||.|| . ..|||||.|||.|..||..||| ...
lpenkdknrypdilpydhsrvklsilpglflsdyinAsyidgyyikrrfiatqgPlpetvedfwrmlwelgitvivmLtslvelgrekcaqywpl.ggsl
TYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASDRPIVAHCSAG
.|| ..| . ...|....|.. .. . .| |. ..... .|||||||. . ..|||.. ||.|.... .. |.. |||||
eygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaG
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 512-719 | 1.3e-61 | 203.8 | In-house | 3-216 (278) | alignment | ||
Range on Protein: 512-719
Range on HMM: 3-216/278.0
ADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKlaaladdsdtDYINANYIPGYnsPREFMACQGPLPGTVDDMWRMIWEKKTS
|... ... |.....| | . | || |..|||...||||.||||| |||||.||.|| |..| |.||||| ||.| |||.|| ...
alasldlllefefllllgipseitpalylgnldknRykdilpydhsrVk..........dYINAsyidgy..pkkfIatqgPlpstvadfwrmlwelgit
IIVMLTQLVEKGKIKCHEYWPaDYNPVTYGSIQVSVQALQQYDHWVIREFSIS------QGDEIRKLTQYHFMSWPDHGVPEKT--WTMLDFVRTVREAI
.|||||.|||.|..||..||| . ...||| ..| .. ...|....| . . ...| |..|..|...|||||||. . . .|.... .|||.
vivmltelvelgrekcaqywp.eggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefireal
Q-----------KTASDRPIVAHCSAG
. |. |.. |||||
kllaslllsslllldsggpvlVHCsaG
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 517-719 | 2.2e-61 | 202.5 | In-house | 27-237 (306) | alignment | ||
Range on Protein: 517-719
Range on HMM: 27-237/306.0
RFTEEYDEIRLVGKDQAI--VSALEMVNRAKNRFTNILPYEHSRVKLAaLADDSDTDYINANYIP--GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSI
|.||..|.. . . . . . |. |||. ||||..|.||.|. . ...|||||||| .| ....| || |. || | |||.|.... .
gfeeefeelqqeeakkllsrkegakpenkeknryknilPfDhtrvilk.epsvpgsdyinanyikkevkgsdksyiatqgclettvsdFWrmvwqensrv
IVMLTQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSIS---QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTA--
|||.|. ||.|| || |||. . .||.|.|. . .. .....||.|.| ...| |.. |||| ||||||||... ..|||...|.. ....
ivmttkevErgkekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleea
SDRPIVAHCSAG
. .||| |||||
eagpivvhCsaG
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 539-719 | 4.1e-61 | 201.8 | In-house | 6-186 (245) | alignment | ||
Range on Protein: 539-719
Range on HMM: 6-186/245.0
EMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAdYNPV
..|. |||...||||.|.|||| | |.|||||.|..||. .. | |.|||||.||.| |||.|| . ..|||||...|.|..||..||| ...
lpenkdknrysdilpydhtrvklspdggdldsdyinasyvdgyritpkfiatqgPlpetvedfwrmlwelgittivmLteeeelgrvkcaqywpl.gesl
TYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKtASDRPIVAHCSAG
||| ..| . ...|....|..... . || |. ..||...|||||||. . ..|||.. ||.|... |. |.. |||||
tygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae.dsngpvlVHCsaG
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 510-720 | 5.9e-61 | 201.3 | In-house | 21-234 (298) | alignment | ||
Range on Protein: 510-720
Range on HMM: 21-234/298.0
MKADSDFRFTEEYDEIRLVGK---DQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIW
.|. . ....|. ... | . .. | . |. |||...|.....||| | . .| ..||||| .. .|. |.|.|.||. || | |||..
kkkkkltgyalefqrlnsvsseieeeekevarkpenkkkNRyadiialdssRvvLekedadeesdYiNAsflhaykgrnafiatqaPltetvedFWrmvt
EKKTSIIVMLTQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREaIQ
|.. . |||||.|.|..|.|.|.||| . . |||.|.||... ... ..|.. .|. . . |.. | ||.||||.||||.. ..||..| || |
eedigtiVmltnleeldktkyhkywPde.gketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvra.sq
KTASDRPIVAHCSAGA
. | ..|.. .||||
qqagnkpvivqCsaGv
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 496-719 | 2.1e-60 | 199.4 | In-house | 2-226 (305) | alignment | ||
Range on Protein: 496-719
Range on HMM: 2-226/305.0
KPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVgKDQAIVsALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLP
|.| |.... . ....|| . ..|... ... | . .|.||||...| .....|..|.. .. |.|||||.|. ||.. .... ||||.
kiialddlaayikearvysdkgleaqykslyee.eesidv.gkkeankaknrlkeitlldddriiltekeslddsdyinasyvdgykrkkkyivaqgPlk
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP-VTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPEKTWT
||.| ||.|.| |.| |||||.||| || ||. ||| . . .|...| .. ... ...|...||. .| | ..||.. .|||||||... .
ntvadfWrliveekvstivmltklveggkdkCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfats
MLDFVRTVREAiQKTASDRPIVAHCSAG
.|.... |... || . |.. |||||
llslikrvqkd.qkkdkgvpllVhCsag
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 506-720 | 4.8e-59 | 194.7 | In-house | 12-221 (314) | alignment | ||
Range on Protein: 506-720
Range on HMM: 12-221/314.0
HYGRMKADSDFRFTEEYDEIrLVGkdqaIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMI
. .|. . | |||. . . | .| . ||.|||...||.|..|||.| .. .|...|||||..| .|. |..|.. ||||. || |.||..
siallkraegygfkeeyesl.feg....wdaakkdenreknrsgdilaydrsrvflitidgdpssdyinaalidsykrpaafivtqgPlqetvkdfWrlv
WEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPvtYGSIQVSVQALQQYDHWVIREFSISQ----GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVRE
...... |||||.|||.|..|| .||| | . || |.| . . |.| |.... .|||.. |..|..||||.|| . ..|..|| | .
ydencasivmltelvevgrvkClkyWPedtev..ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkk
AIQKtaSDRPIVAHCSAGA
.. .. .|| ||||||
sqee..eaGrivvhCsaGa
|
|||||||||
subfamily_PTPRD_pd | Subfamily PTPRD | 721-880 | 7.2e-59 | 194.9 | In-house | 131-289 (564) | alignment | ||
Range on Protein: 721-880
Range on HMM: 131-289/564.0
IKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktASDRPIVAHCSAGVGR
|||.|||.. .. |||...|.... ... . .||.|... . .| |. .|.||.||||||||... ..||..|.||.. . ||| ||||||||
vkchkYWPek.gtetygeltVtleeeeeladyeirtfklkkkkssesreVrqFhFtsWPdhgvpesatslLdlirkvralne..pdagPivVhCSaGVGR
TGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEEDT
|||.|..| ... ..|.. .||.... ..| |||.|||||.||||||| ... | |..| .
TGtfividamlerikeektvDiyqyvkalrkqRnamVqteeQYiFiheailealacgnteve
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 497-720 | 8.4e-59 | 194.2 | In-house | 3-230 (307) | alignment | ||
Range on Protein: 497-720
Range on HMM: 3-230/307.0
PIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPG
.| . . | . | |.|| ...||... |. . . . | |||. .| .... ||||. . . |.|||||..| ||. ..|.| |.|. .
aiaiddleealksrkrdtdfglakeyekLeareidkstkvsekkenalknRyedikafDktRvkLkkingkedsdYinasfikgykekkkfiaaqdPvea
TVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQGD-------EIRKLTQYHFMSWPDHGVPEKT
|..| ||||.|.. .||||..| || . ||. ||| . . | ||.| | . .. ....|||...|. . . ||..|||...|.| ||| .
tigDfWRmiaeqevtlivmlsnlteknrkkcakYWpie.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPeva
WTMLDFVRTVREAIQKTasDRPIVAHCSAGA
..|.... ||| .. ||| |||||.
rgllklieqvrelykln..rsPivvhCsaGv
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 535-720 | 8.6e-59 | 194.0 | In-house | 36-220 (515) | alignment | ||
Range on Protein: 535-720
Range on HMM: 36-220/515.0
VSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPA-
| | .| |||. |||||. .|||| . |. . ||.|| |||.... . ..| |||.. .|||.||........ |.|.|.| | |||| .|||
tvaqeeinfkknryknilPydsvrvklevindnPhsdyfnasyipsfdndkayiasqgPnkasvddfWrlvlqenvttiamvtklkegdkikcgkyWPdk
DYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTAsdRPIVAHCSAGA
. | .|||.|.. .|. ..|.. . .||..| .||.|| |||.|||..| ..| ... |. .. . |.. |||||.
pgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt..hpliihcsaGv
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 540-720 | 1.8e-58 | 193.3 | In-house | 59-235 (319) | alignment | ||
Range on Protein: 540-720
Range on HMM: 59-235/319.0
MVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTqlvekgKIKCHEYWPADYNpVT
|. |||..|||......||| | .||||| .. || .. ..|.||||. |..|.|||||| ..| ||.|| | || .||| . . ..
dqnkdknriinilafdknvvklerliGeefsdyinasfvtGyqrkdkyiaaqGPldntladfWrmiweyncstivllt......kdkcsqywplkiv.ik
YGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGA
.. .|.|..... . .|.|.. .|. .|||.||.||. |||.|||. . .. .|. || .| ..|| |||||.
eerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGv
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 519-719 | 2.4e-58 | 192.5 | In-house | 19-233 (297) | alignment | ||
Range on Protein: 519-719
Range on HMM: 19-233/297.0
TEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
..|| ||| . . .| |||.|..| |...||.|| . .|. .||||||.. ||. .. |.| ||||. ||.| |||.||... .||| |.
skeyaeirnepveGtflasklranleknrytdvlcydetrvvlakvdedeasdyinanfvdGykqkkafiatqGplkktvsdfWrmvWeqevlvivmttr
LVEKGKIKCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQ-----------
.||.|..|| .||| . . .|...||. ........| . |. . .|.||.| . |.||||.|||. . ..||....|||.
vvergrlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewk
KTASDRPIVAHCSAG
.|. ||| |||||
ghpsgPPivvhcsaG
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 542-720 | 6.3e-58 | 191.3 | Pfam-A | 1-181 (235) | alignment | ||
Range on Protein: 542-720
Range on HMM: 1-181/235.0
NRAKNRFTNILPYEHSRVKLaalADDSD-TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWP-ADYNPVT
|. |||...||||...|||| .... .|||||||. ||.....|.|.||||. |..| |||.|..|...|||||.|.|||. ||..||| .. ...|
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGSIQVSVQ-ALQ-QYDHWVIREFSISQGDEI---RKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIqkTASDRPIVAHCSAGA
||.|.| .. . . .....|...... .| |...|.|. .||||||||.. .||..| |.. .|.. |.| |||||.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGv
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 542-720 | 6.3e-58 | 191.3 | In-house | 1-181 (235) | alignment | ||
Range on Protein: 542-720
Range on HMM: 1-181/235.0
NRAKNRFTNILPYEHSRVKLaalADDSD-TDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWP-ADYNPVT
|. |||...||||...|||| .... .|||||||. ||.....|.|.||||. |..| |||.|..|...|||||.|.|||. ||..||| .. ...|
nkkknRykdilpydktrvkl...kgsegpsdYInAnyvkgykekkkfIatQgPlkstiedFWrmvwqekvkvivmltsleekgrekcaqYwpeeeeeslt
YGSIQVSVQ-ALQ-QYDHWVIREFSISQGDEI---RKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIqkTASDRPIVAHCSAGA
||.|.| .. . . .....|...... .| |...|.|. .||||||||.. .||..| |.. .|.. |.| |||||.
ygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsaGv
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 537-719 | 1.2e-57 | 190.6 | In-house | 5-188 (243) | alignment | ||
Range on Protein: 537-719
Range on HMM: 5-188/243.0
ALEMVNRAKNRFTNILPYEHSRVKLaaladdSDTDYINANYIPGYnsPReFMACQGPLPGTVDD----MWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWP
|| ..|. |||...||||.|||||| ...||||||.|... || . |.|||||.||.| |||.|| ....|||||.|||.|..||..|||
allpenlsknrysdilpydhsrvkl......egsdyinanliyvt..pr.liatqgPlpetveddlasfwrmlwelgitvivmltelvElgrekcaqywp
adyNPVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQK------TASDRPIVAHCSAG
..|||| ..| . ...|....|..... .|. | ..||...|||||||. . .|||.. ||| |.. |..|.. |||||
...gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvlVHCsaG
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 541-720 | 1.2e-57 | 190.5 | In-house | 24-199 (284) | alignment | ||
Range on Protein: 541-720
Range on HMM: 24-199/284.0
VNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTqlvekgKIKCHEYWPADYNpVTY
|. |||...||......||| | .||||| .| || .. ..|.||||. |..|.|||||| ..| ||.|| | || .||| . . ...
qnkdknrighilafdknvvklerliGeefsdyinasfitGyqrkdkyiatqGPldntladfWrmiweyncstivllt......kdkcsqywplkiv.ike
GSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGA
. .|.|..... . .|.|.. .|. .|||..|.||. |||.|||. . .. .|. || .| ..|| |||||.
erfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagv
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 518-720 | 2.3e-57 | 189.2 | In-house | 21-221 (315) | alignment | ||
Range on Protein: 518-720
Range on HMM: 21-221/315.0
FTEEYDEIRLVGKDqAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
|.||. .. .| | .| |||. ||||....|||| . |. | ||||| ||..... . ..| ||||. .|||.|||....|.. |||.|
fseefhdlpdPdiy.rqrvaretinfkknryknilPldsarvkleviddsPdsdyinasyiksvdddkayiasqgPlkasvddfwrmvlqekvttivmvt
QLVEKGKIKCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiqKTASDRPIVAHC
.. | |||| ||| . . | .|||.|.. |.. |.|.. . ...| |..||..| |||.||...| ..| ... |. . . ... ||
kkqegdkikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad..ngkkefsllvhc
SAGA
|||.
saGv
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 521-719 | 8.6e-57 | 187.2 | In-house | 20-218 (280) | alignment | ||
Range on Protein: 521-719
Range on HMM: 20-218/280.0
EYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLaalaDDSDTDYINANYI----PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVML
..... .. || | | .|||. .||||.. |||| ..|.||||||||. |. . ..|.||||. |. |.|.|.||.|.|.||||
qfeqlyrkkpglaisaarkpenlsknryrdilpydatrvkl....kesetdyinanyvnmeipstglvnryiatqGPlaktatdfWqmvweqksslivml
TQLVEKGKIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiqKTASDRPIVA
|.|||.|..|||.||| . ..||...| .. .. .|.||. ... . | ||..| ...|||||||... .|.||..||.. ......|.|
ttlverGrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrkl..rsgkeePvvv
HCSAG
|||||
hCsaG
|
|||||||||
subfamily_Urchin-PTPRB-like_pd | Subfamily Urchin-PTPRB-like | 721-872 | 1.2e-56 | 186.9 | In-house | 130-279 (288) | alignment | ||
Range on Protein: 721-872
Range on HMM: 130-279/288.0
IKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTasDRPIVAHCSAGVGRTG
||.||||.. .|. |||..| .. .. ...| |.. . . . ...|||....|||||||. . .|...|.| | |. ||. ||||||||||
tkCeeYWPdadkpknyGsvtvtlveskeledfvlrklllekkkteleitqyqylaWpdhgvPeskapllellrqvkvanqad..tgpiivhCsaGvGrtg
TYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
|.|||| |..|..|.||||..|.....|.||. .|||.|||.||.|....|
tFialdalidaveeedyiDvagtvaklRkqRallvqtlkqYefiyevllsli
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 539-720 | 3.7e-56 | 185.1 | In-house | 6-186 (250) | alignment | ||
Range on Protein: 539-720
Range on HMM: 6-186/250.0
EMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIkCHEYWPADyNPV
.. |. |||...|.....||| | | ..||||| .. ||. . |.| ||||. |. |.|||..|.|.. |||||.|.|..| .|.|||.. ..
kpqnkeknryadiialdssrvvLekekgdkesdyinasflhgyderkafiatqgPlqatiedfWrmvleeksgtivmLtnLkesekt.yhqywPve.kae
TYGSIQVSVQALQQYDHWVIREFSISQGDEIRK--LTQYHFMSWPDHGVPEKTWTMLDFVRTVReAIQKTASDRPIVAHCSAGA
.||...||. ... ...|.. .|. . . . |.||..||| ||||.. ..|.... |. | |. | ..|.. .||||
kyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvq.asqqqagnaPvivqCsaGv
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 519-719 | 1.2e-54 | 180.5 | In-house | 14-212 (273) | alignment | ||
Range on Protein: 519-719
Range on HMM: 14-212/273.0
TEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADdsdtdYINANYIPG--YNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVML
.||..|.| . . .. . |..|||. |.|||...|||| . . ||||..| . |..||||||| ||.|.|.|.||.|...|.|.
aeefkelrelkpldtcevgkkkenkdknryrnvlPydetrvklgdegg.....yinaslikvpvgkdeyeyiacqGPlPetvkdfwqmvweqkaeviamv
TQLVEKGKIKCHEYWPADYN-PVTY-GSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREaIQKtaSDRPI
|. .||||.||| ||| | ... . ..|.. .|..| .|.|.. .. . | |.... .|..||||||| .. .| ||. ||. .|. . ||
tlekekgkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrr.lqt..dagPi
VAHCSAG
| |||||
vvhcsaG
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 542-719 | 4.4e-54 | 178.4 | In-house | 28-211 (274) | alignment | ||
Range on Protein: 542-719
Range on HMM: 28-211/274.0
NRAKNRFTNILPYEHSRVKL-AALADDSDTDYINANYIPGYNS-PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP--
. |||...||| |.||| | .. ..|.|..||||||| ||. . ..| ||||| ||.|.||||.......|||||.| |. . ||..|.| . .
sqtknryktilPnensrvllesessededssyinanyikGydeeskayvatqGPlpntvadfWrmiyqeevqvivmltklkeaneqkCavyfPdaedyei
-VTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASD-RPIVAHCSAG
.|| ... |. . ... .|...... . |... | . .|||| .|... |.||.|. |.|. .... |.| |||||
serygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaG
|
|||||||||
subfamily_Anemone-PTP-6_pd | Subfamily Anemone-PTP-6 | 720-879 | 3.9e-52 | 172.3 | In-house | 128-287 (318) | alignment | ||
Range on Protein: 720-879
Range on HMM: 128-287/318.0
AIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiQKTASDRPIVAHCSAGVG
.|.| ||| . .. .||...| .. .....|.|||.... .| |. |||. ||||.|||... ..||.||.|..| |.... .||| |||||||
kakvhryWPsk.gsrsygklvvelkeevelsdyvlrefkvtrteeeesrqvrqyhytsWpdegvpesgaslldlvrqvska.qqksgagpivvhCsaGvG
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEED
|||..||.| |.. .... .|.|... ..| ||| |||||.||.||.. ... | |. |
rtGvfiavdillerikaealvDvfqtvkqlreqrnlmvqtedqyefiydvllealasgdtev
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 541-719 | 6.7e-52 | 171.1 | In-house | 19-207 (270) | alignment | ||
Range on Protein: 541-719
Range on HMM: 19-207/270.0
VNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP--
... ||...||| ..||.|. | .|| | ||||||..|.. ......| .|||| |. . ||||||.|.. |||.|.|.|||. || ||||. .
rgkklnRyadiLPsPatRvrleeleedsataYinAnyvrGfdgekkkYiaamgPlpttlksfwrmiweekvtaivmttgleEkgrkkCerYWpaepkekv
-VTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTW------TMLDFVRTVREAIQKTASDRPIVAHCSAG
...| |.| ... .. . ..... . . |.|.|. ... .|||||||... .| .|.||. .... |.. |||||
kledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvHcsaG
|
|||||||||
0046845 | (Phosphotyrosine protein) phosphatases II | 720-874 | 8.8e-52 | 171.6 | In-house | 116-276 (284) | alignment | ||
Range on Protein: 720-874
Range on HMM: 116-276/284.0
AIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGV
.||. ||| . ...||| ..| . ...|....|..... ..| |..|..|..||||||||. . .|.|.|.|||..... .. ||| ||||||
rekcaqYwplegevltygdftvtllseevkddytvrtleltnlgytgesrtvthfhytswpdhgvppspedlleflrlvrellenlpgggpivVHCsaGv
GRTGTYIALDRLMQAMQEND---YIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
|||||.|||| |.. ..... .|...... .|.||..||||. ||.|..|.....|..
gRtGtfialdllleqlekeglllgvdvleavkrlreqRpgmvqtleqyrfvyealleylkl
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 496-719 | 2.3e-51 | 169.7 | In-house | 8-227 (297) | alignment | ||
Range on Protein: 496-719
Range on HMM: 8-227/297.0
KPIVLNKFEGHYgRMKADSDFRFTEEYDEirLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSprEFMACQGPLP
.|| | .| . . ..|. | . . . |. | . || |.|..|||||. |||||| . || | ||.|| ...|.. .... | | .
rpiplsdfatlv.qknrhtdvfseeflcl..peaniqpqtvaekkvnfeksRYkniLPydssRvkLaivnddpdsDyvnasfvkgnkh..rlittqmPmk
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKiKCHEYWPaDYNPVTYGSIQVSVQALQQYDHWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPE--KTWT
||.|.|.|......|.||||... |. | || ||. | .|.|.. | ...... . ||.....|. | . ||.|..|||. |.. .. .
atvadfWamvldeqvstivmlnddnerdk.kcaryWs.dkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsass
MLDFVRTVREAIQKTASDrPIVAHCSAG
.|... ||. ...|. |.. ||.||
llklisevrkdfsqnaeg.PllvhclaG
|
|||||||||
0050432 | (Phosphotyrosine protein) phosphatases II | 719-874 | 7.8e-51 | 168.6 | In-house | 146-301 (308) | alignment | ||
Range on Protein: 719-874
Range on HMM: 146-301/308.0
GAIKCHEYWPAD--YNPVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIqktaSDRPIVAHCSA
| .||..||| . ....|| ..| . ...|....|.. .. ..| |..|..|...|||||||... .|||.. ||. . .. ||| ||||
grekcaqYwplelgggsleygkftvtllseevlddytvrtleltnlgdgesrtvthfhytnWpdhgvPpspeilldflelvrksl....pggpivVHCsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
|||||||.|||| |.. .... .|.|.... .|.||..||||. ||.|........|..
GvGRtGtfialdllleqlekeggvdvfeavkklReqRpgmvqtpeqylflyralleylkl
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 505-719 | 8.2e-51 | 168.0 | In-house | 12-231 (325) | alignment | ||
Range on Protein: 505-719
Range on HMM: 12-231/325.0
GHYGRMKADSDFRFTEEYDEIRLVGkDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRM
| . ||. . |. |.. . .. .| | |.||||| |......||| | .. ||...|||||.|. . |.|.| ||. |..|.||.
ehvekkkaqdqdgfahefgllpsdd.giakkvamkpenkaknrfknvvaldksrvvletkkddpssdyinasylrddkkkdvflaaqaPltatindlWrl
IWEKKTSIIVMLTQLvEKGKIKCHEYWPAD-YNPVTYGSIQVSVQALQQYDHWVIREFSISQG--DEIRKLTQYHFMSWPDHGVPEKTWTMLD---FVRT
. . ..|..|.| .| ..|| .| ||| . . .|.|...|........ .| | . . | | | . |....||.| ||... |.. | .
vldWrcsvvvvlnel.dlgkdrcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvka
VREAIQK-TASDRPIVAHCSAG
| | .. | . ||. |||||
vservtantkastpilvhcsaG
|
|||||||||
subfamily_Anemone-PTP-5_pd | Subfamily Anemone-PTP-5 | 720-878 | 1.2e-50 | 167.4 | In-house | 130-289 (319) | alignment | ||
Range on Protein: 720-878
Range on HMM: 130-289/319.0
AIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQ-GDEI--RKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTaSDRPIVAHCSAGV
.|...||| |...|| . | .. .. ....||.... . .|. |.........||||.||.|. ..||... .|.. .|| ...||| ||||||
kvklkkywpee.nfeeyGrlivtleeeeeledyiirklklnkkssevetRevkhfqyteWpdhdvPekatslldllkrirksrekt.qsgPivvhCsaGv
GRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEE
|||||.|.|| .. ..|. .|.| .. ..|.||| |||...||.||.| ... . |. |
GRtGtfivldamlervkeegvlDvfstvsrlRtqRnimvqrpeqYkfiyealleaveagdte
|
|||||||||
0051299 | (Phosphotyrosine protein) phosphatases II | 719-872 | 1.7e-50 | 167.4 | In-house | 130-286 (288) | alignment | ||
Range on Protein: 719-872
Range on HMM: 130-286/288.0
GAIKCHEYWPAdYNPVTYGSIQVSVQALQQYDHWVIREFSIS------QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktASDRPIVAHC
| .||. ||| ...||| |.| ...|....|.. .. ...| |. |..|...|||||||| . .|||.| ||.|.. ... |.| ||
grekcaqYwpl.ggsltygditvtllseevlddytvrtlevtnldlldgdgesrtvthfhytnwpdhgvpdspellldflrlvrkala..sgggpvvVHC
SAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
|||||||||.|||| |.. .... .|...... .|.||..||||. ||.|..|.....|
saGvgRtgtfialdllleqlekeggvdvleavkrlreqRpgmvqtpeqyrfvyealleyl
|
|||||||||
subfamily_Choan-PTP-1_pd | Subfamily Choan-PTP-1 | 719-874 | 2.4e-50 | 166.2 | In-house | 122-278 (281) | alignment | ||
Range on Protein: 719-874
Range on HMM: 122-278/281.0
GAIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSI-SQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiQKTASDRPIVAHCSAGVG
| .||| ||| | . ..|| ..|. .| .. ... |.|.. .. | |...| ....|||||||..| .|.| . |... ... .. |.| |||||||
gklkChrYWPddnselkygdvtvkstaeeekatyierkfkleresgetreveqlaytaWPdhGvPattkellefrkevlkl.tekktkaplvihCsaGvG
RTGTYIALDRLMQAM-QENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
|||||||||||..|. .|. .|. .. |.| .|| |||| || |.. |.| | .
rtGtyialDrlvkaveaeleeldvkavvaelrkernlmvqtvvqyefvykavldaldk
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 518-719 | 3.4e-50 | 165.5 | In-house | 23-222 (288) | alignment | ||
Range on Protein: 518-719
Range on HMM: 23-222/288.0
FTEEYDEIRlvGKDQAIvsALEMVNRAKNRFTNILPYEHSRVKLAaladDSDTDYINANYIPGYNS--PrEFMACQGPLPGTVDDMWRMIWEKKTSIIVM
|.... ....| |. .. |||...||||.|.|||| .| ||||| .. . . | .|.| |.||..|. | |.|..|.|.|.|||
eleqkqdke..arkrsi..aiaklyseknrsrdilPyDhnRvklr....gskDDYinAsfvkdlspgcP.dfiatqaPlqstlnDFWlmvyeqkssviVm
LTQLVEKGKIKCHEYWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVRE--AIQKTASDR
|.. |.|| |...|||.| ..|..| ..|... .. ...| |..... . |...... ...|||..|||. |.|.|. |.. .. |.
llskeelgkpkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrkskt
PIVAHCSAG
|.| |||||
PlvvhCsaG
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 542-719 | 3.8e-50 | 165.3 | In-house | 3-182 (237) | alignment | ||
Range on Protein: 542-719
Range on HMM: 3-182/237.0
NRAKNRFTNILPYEHSRVKLAALAddSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTY
|..|||. || |.|||| | |..|||||.|. |.. .|....|.|||| . ||.|.|.|..| |.||||| |.|. ..|||.||| .| .|
nkiknrygnivaydhsrvvlkgag..sgsdyinatylkgfdgtpkkyiaaqgplesscddfwqmvwqekcsvivmltgliegnelkchkywpstdqpaay
GSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASDRPIVAHCSAG
| . ||.. ... . .| . .|. |.| . ||.| ||||.|||..| ..| | . . . .. . | . |||||
gvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsag
|
|||||||||
0039614 | (Phosphotyrosine protein) phosphatases II | 720-874 | 1.7e-49 | 164.3 | In-house | 140-291 (297) | alignment | ||
Range on Protein: 720-874
Range on HMM: 140-291/297.0
AiKCHEYWPADYNpvTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVGRT
||..||| . . ||| ..| . ...|....|..... ..| |..|......|||||||. . ..|.|.. ||||.... ...|.. |||||||||
r.kcaqywpeegg..tygdftvtllkvehldgytvrtlevtnngesrtvthfqytgwpdhgvppslellleflelvrealaelpkggpvlVHCsaGvgRt
GTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
||.||...... .... .|.. ...|.|.||...|||. ||.|.......||.|
GtfiaaylmleqlekeggvdvleavkelreqRpgavqtpsqyrflydallellkr
|
|||||||||
0047943 | (Phosphotyrosine protein) phosphatases II | 719-871 | 5.4e-49 | 162.5 | In-house | 115-271 (273) | alignment | ||
Range on Protein: 719-871
Range on HMM: 115-271/273.0
GAIKCHEYWPADYN--PVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSA
| .||. ||| . . ..||| ..| . ...|....|.. .. .| |. |..|...|||||||. . .|.|.. ||.|.... |. |.| ||||
grekcaqYwpleggelsltygkftvtllseetkddytvrtleltnlgtgesrtvthfhytgwpdhgvppslesllefielvrkalealpsngpvvVHCsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
|||||||.|||| |.. .... .|.. ... .|.|| .||||. ||.|..|.....
GvgRtgtfialdllldqlekeggvdvleavkllrsqRpgmvqtpeqyrflyealley
|
|||||||||
0036941 | (Phosphotyrosine protein) phosphatases II | 719-875 | 8.3e-49 | 161.8 | In-house | 116-280 (297) | alignment | ||
Range on Protein: 719-875
Range on HMM: 116-280/297.0
GAIKCHEYWPAD-YNPVTYGSIQVSVQALQQ--YDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCS
| .||..||| . ...||| ..| .. .. .|....|.. .. ..| |..|..|...|||||||. . ..|||.. ||...... |. |.. |||
grekcaqywpleegesltygdftvtllsvevvllddytlrtlevtdtgngesrtvthfhytgwpdhgvpespaslldfielvrkvlkllpsggpvlVHCs
AGVGRTGTYIALDRLMQAMQ---ENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRG
|||||.||.||.| ..| .. .. .||. .....|.||...|||. ||.|..|....||...
aGvgRsgtfiaadlmlqqledklkeggvdileavkklReqRpgavqtleqyrflyeallellkkk
|
|||||||||
0040438 | (Phosphotyrosine protein) phosphatases II | 720-879 | 1e-48 | 161.6 | In-house | 125-283 (317) | alignment | ||
Range on Protein: 720-879
Range on HMM: 125-283/317.0
AIKCHEYWPAdYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktASDRPIVAHCSAGVG
.||..||| ...||| ..| .. ........|.. .. ...| |..|..|...|||||||. . ..|||.. ||||.. .. |.. |||||||
rekcaqYwpl.getltygdftvtllseeelagitlrtlevedlgdsesrtvthfhytgWpdhgvppspdllldfleavreale..dpggpvlVHCsaGvg
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEED
||||.||...... .... .|.. ...|.|.||...|||. ||.|........|.|..
RtGtfiaaylmleqlekeggvdveeavkelreqRpgavqtpeqyrflydalleylkrkltle
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 516-719 | 2.2e-48 | 159.4 | In-house | 6-211 (290) | alignment | ||
Range on Protein: 516-719
Range on HMM: 6-211/290.0
FRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVM
...| | .|| .| . .| . ||..||. .. ||.|||.|| ..|.|||||. . . |... ||||| ||| .|.|.||.|. .||
rlykeiyldirkeasdfptreaklpenrnlnryrdvspydhsrikle....radndyinaslveleeakrsyiltqGPlpntvdhfWqmvWeqkskavvm
LTQLVEKGKIKCHEYWPADYN--PVTYGSIQVSV--QALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASD
| ..|||..|||..||| . . ... ....| . ........| . . . .| |.....|...||| |||| ..|.|. |||. .
lnkvvekeqikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdv
RPIVAHCSAG
| | |||||
GpavihcsaG
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 500-719 | 2.3e-48 | 159.5 | In-house | 4-226 (290) | alignment | ||
Range on Protein: 500-719
Range on HMM: 4-226/290.0
LNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSD--TDYINANYIPGYNSPREFMACQGPLPGT
..|| . .| . .| ... . ..... .| |. .|||.||..|. |. | .... | .|||| || ||. ....| |||.. |
vdkfgefvanghakgnegfrnqfkmldsgesehtvtvgltssnkllnRfanivvyddnritLrpisghkDCtneyinAcyikgykekkqyiatqgpvsnt
VDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVtYGSIQVSVQALQQYDHWVIREFSISQGDE---IRKLTQYHFMSWPDHGVPEKTWTMLD
. | |..||..|..||||||. .|.|| ||. |||. . || ... .. ..... ..|.... . .. ...|||.. .|...| ... |.|
lvdFWkliwqekvtiivmltniieegkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtill
FVRTVREaIQKTASDRPIVAHCSAG
.. . . .|. ...|| |||..
vieemyk.tqrkrgntsivvHCSdt
|
|||||||||
0045450 | (Phosphotyrosine protein) phosphatases II | 720-873 | 6.3e-48 | 159.5 | In-house | 146-305 (307) | alignment | ||
Range on Protein: 720-873
Range on HMM: 146-305/307.0
AIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSIS---QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGV
.||..||| . ..||| ..| . ...|....| . .. . .| |..|..|. .|||||||. . ..|||.. ||.|.... .. |.. ||||||
rekcaqywPdegeeltygnftvtllseehldgytvrtlevtdldgtgesrtvthfhytgwpdhgvppsfeelldfieevrkaleelpkggpvlVHCsaGv
GRTGTYIALDRLMQAMQENDY---IDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
|||||.||.. ... .... .|.. .....|.|| ..||.. ||.|..|....||.
gRtGtfiaaylmlrqlekegtlldvdlleavkllreqRpgavqnpeqyrflyeallelll
|
|||||||||
0043336 | (Phosphotyrosine protein) phosphatases II | 720-872 | 1.2e-47 | 158.1 | In-house | 127-277 (278) | alignment | ||
Range on Protein: 720-872
Range on HMM: 127-277/278.0
AIKCHEYWPadYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktASDRPIVAHCSAGVG
.||..||| ...||| ..| .. ...|....| . .. . .| |. |.||...|||||||. . ..|||...||||.. |. |.. |||||||
rvkcaqYwp..ggsltygdftvtllkeehlddytvrtlevtnlgdgesrtvthyhylgwpdhgvpeslsllldflkavreale..dsngpvlVHCsaGvg
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
||||.|||..|.. .. . .|.. ...|.|.|| ..|||. ||.|..|.....|
RTGtfialyllleqlekeggvdleeavkelreqRpgavqtpsqyrflyealleyl
|
|||||||||
subfamily_PTPRA_pd | Subfamily PTPRA | 722-877 | 4.1e-47 | 155.7 | In-house | 142-300 (330) | alignment | ||
Range on Protein: 722-877
Range on HMM: 142-300/330.0
KCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSIS-QGDE-----IRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASdrPIVAHCSAG
||. ||| . |||| |.|.|. . .. .|.| . ..|. | ..|.|| |||| ||| .. ||.... |.. |..|. ||| |||||
kcaqywPde.GlvtyGnirvevedetvlvdytvrkflvqqlpdatrekksrlvrqfhftswPdvGvPfepiGmlkllkkvkklnqqsag..pivvhcsaG
VGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEE
||||||.|.|| ... .. . .|.|... ..|.|| .||||..|| ||.. ... |.
vGrtGtfivldavlervkaerkvdvfefvkrlrlqrpqmvqtdeqyefiykvlleyylygdt
|
|||||||||
subfamily_Urchin-PTPRA_pd | Subfamily Urchin-PTPRA | 722-870 | 2.6e-46 | 153.4 | In-house | 139-289 (319) | alignment | ||
Range on Protein: 722-870
Range on HMM: 139-289/319.0
KCHEYWPADYNpVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVGR
|| .||| . . .... .|.|..... . .|.|.. .|. .|||.||.||. |||.|||| . .. .|. || .| ..|| ||||||||
kcsqywplkiv.ikeerfkvkvdsveetaeyvvrdielsedgkekdirkitqfhflGwpdvGvpdypsdlmrlvkkvrhltskenhranivvhcsaGvGr
TGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
||.||.|| |.. |.|.. .|.. .. ..| |||..|| || ||. ...
tGvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
subfamily_Anemone-PTP-2_pd | Subfamily Anemone-PTP-2 | 721-877 | 2.8e-46 | 153.1 | In-house | 139-295 (298) | alignment | ||
Range on Protein: 721-877
Range on HMM: 139-295/298.0
IKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaIQKTASDRPIVAHCSAGVGR
.|.|.||| . . |||.|.||... ... ..|.. .|. . . |.. | ||.||||.||| .. ..||..| || |. | ..|.. .|||||||
tkyhkywPde.gketygeitvsllskeefadlivrklkvskkkeekerevrqlhftsWpdkgvpenatsvldllrkvra.sqqqagnkpvivqCsaGvgR
TGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEE
.||.||.| ... .... .|.| .. .|..| ..||||.||.||.| |.. | ...
sGtfiaidsvlervkkeqvvDvfqvvkvlRkkrpgavqteeqYvfiyeavlealdsfnd
|
|||||||||
subfamily_Sponge-PTP8_pd | Subfamily Sponge-PTP8 | 722-881 | 2.9e-46 | 153.0 | In-house | 130-292 (305) | alignment | ||
Range on Protein: 722-881
Range on HMM: 130-292/305.0
KCHEYWPADYNP-VTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiQKTASDRPIVAHCSAGVG
||. ||| . . .|...| .. ... ...|...||. .| | ..||.. .|||||||... ..|.... |... || . |.. |||||||
kCrqYWpesktekkefgefsvelksektasdyieRklkisiededkesrtvlqyqltdWPdhGvpqfatsllslikrvqkd.qkkdkgvpllVhCsagvg
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEEDTG
|||..||.| .. ... . .|.|... ..| .| |||| .|| |.|. . .|. |. . |
RtGvfiavdialerlkkEevvdvfevlkqlRskrmkmvqtldqYvflhdaldelitcgdtsiig
|
|||||||||
DSPc_SM00195 | 720-872 | 4.1e-46 | 152.8 | In-house | 108-262 (263) | alignment | |||
Range on Protein: 720-872
Range on HMM: 108-262/263.0
AIKCHEYWPADY-NPVTYGSIQVSVQALQQYD-HWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTasDRPIVAHCSAG
.||..||| . .. |.|.|.| .. .... ....|...... . | ||.|||.. .||||||||.| .|...|.|.. ... . ||| |||||
kekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpivVhCsaG
VGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
||||||....| ... ..|.. .||| |..|.|.|| .||||..||.||.|......
vgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
PTPc_SM00194 | 720-872 | 4.1e-46 | 152.8 | In-house | 108-262 (263) | alignment | |||
Range on Protein: 720-872
Range on HMM: 108-262/263.0
AIKCHEYWPADY-NPVTYGSIQVSVQALQQYD-HWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTasDRPIVAHCSAG
.||..||| . .. |.|.|.| .. .... ....|...... . | ||.|||.. .||||||||.| .|...|.|.. ... . ||| |||||
kekcdrywpeesggketfgkisvklvevekkkdeiilrtleltkegkeetrkvtqyqyknWpdhgvpdstksvlellravkksksts..sgpivVhCsaG
VGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
||||||....| ... ..|.. .||| |..|.|.|| .||||..||.||.|......
vgRtgtfvtidiilskleeekkvdifeivkelRkqRpgmvqtleqYlfiyeaileyi
|
|||||||||
subfamily_PTPN12_pd | Subfamily PTPN12 | 721-874 | 5.9e-46 | 151.6 | In-house | 123-279 (290) | alignment | ||
Range on Protein: 721-874
Range on HMM: 123-279/290.0
IKCHEYWPAD-YNPVTYGSIQVSVQALQQYD-HWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktASDRPIVAHCSAGVGR
.||. ||| .....|...|.... .. | ..|| . . . .| ||..|.|...||||||| .. ..|.....||| . ..| |.| ||||||||
kkCerYWpeegeeelefgefevtleeekavdddflirtLkveaqkesrkvyqfhYtaWPDhgvPssaksllelielvrelqe..sedaPlvvhCsaGvGr
TGTYIALDRLMQAMQENDY---IDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
||| ||.| ...... .|.| .. |.| ||. .|||..|| .....|..|...
tGtiiaidyvrellkaekipeeldvfdlvlelrkqraalvqtkeqyelvykavaelvqk
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 510-719 | 7.6e-46 | 151.4 | In-house | 14-221 (287) | alignment | ||
Range on Protein: 510-719
Range on HMM: 14-221/287.0
MKADSDFRFTEEYDEIRLVGKDQA-IVSALEMVNRAKNRFTNILPYEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEK
.| .. |.. . . |.... . .. |. |||.|.||... || | . . ||||| .| ||.. ..|.....|. |. ..|..|...
ghakgnegfknqftvleqvtqredevthniasqnkdknRltqilvpdnyrvllk....gehpdyinavfidgykekkafiiaesPmfntarnfWkliddr
KTSIIVMLTQLVEKGKIKCHEYWPADYNpVTYGSIQVSVQALQQYDHWVIREFSISQGD---EIRKLTQYHFMSWPDHG-VPEKTWTMLDFVRTVREaiQ
. ..||||.|. |. . .|..||| . . |..| .... ........|.. . . . . ....||.. .|...| |.|. .| . . ... |
nvtaivmlcqekendeevcyqyWpeeks.vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemykt..q
KTASDRPIVAHCSAG
. .. .|| |||..
rkrgntsivvhCsdt
|
|||||||||
subfamily_Urchin-PTP-8_pd | Subfamily Urchin-PTP-8 | 722-870 | 9.8e-46 | 151.5 | In-house | 103-253 (284) | alignment | ||
Range on Protein: 722-870
Range on HMM: 103-253/284.0
KCHEYWPADYNpVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVGR
|| .||| . . .... .|.|..... . .|.|.. .|. .|||..|.||. |||.|||| . .. .|. || .| ..|| ||||||||
kcsqywplkiv.ikeerfkvkvdsveeseeyvvrdielsedgkekdirkirqfhflgwpdvgvpdypsdlmrlvkkvrhltskenhranivvhcsagvgr
TGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
||.||.|| |.. |.|.. .|.. .. ..| |||..|| || ||. ...
tgvyivldvlldrmkeekqvdvynfvrdlrqqrntlvqdlvqykfiysalle
|
|||||||||
0045098 | (Phosphotyrosine protein) phosphatases II | 720-875 | 1.4e-45 | 151.2 | In-house | 103-275 (278) | alignment | ||
Range on Protein: 720-875
Range on HMM: 103-275/278.0
AIKCHEYWPaDYNPVTYGSIQVSVQALQQYDHWVIREFSIS------QGDEIRKLTQYHFMSWPDHGVPDKT--WTMLDFVRTVREAIQ-----------
.||..||| . ...||| ..| .. ...|....| . . ...| |..|..|...|||||||. . . .|.... .|||..
rekcaqywp.eggsltygdftvtllseevlddytlrtllvtnltveredlesrgvthlhylpwpdhgvpslpilksflellefirealkllaslllssll
KTASDRPIVAHCSAGVGRTGTYIALDRLMQAMqeNDYIDIFGIICEMRMQRNH-MVQTEKQYIFIHECVMDLLRRG
|. |.. |||||||||||..|.. ... . .. .|.. ...|.|.||.. .||.. ||.|..|....||.||
lldsggpvlVHCsaGvgRtGtlvaaylmlell..eggvdlleavkelrsqRpglavqnleqyrflyefllelllrg
|
|||||||||
0042113 | (Phosphotyrosine protein) phosphatases II | 720-872 | 1.5e-45 | 150.9 | In-house | 91-243 (245) | alignment | ||
Range on Protein: 720-872
Range on HMM: 91-243/245.0
AIKCHEYWPAdYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKtASDRPIVAHCSAGVG
.||..||| ...||| ..| . ...|....|..... . || |. ..||...|||||||| . ..|||.. ||.|... |. |.. |||||||
rvkcaqywpl.gesltygdftvtllseehlddytvrtlevtnlgddesrevihyhylpwpdhgvpdllellldflefvrkalae.dsngpvlVHCsaGvg
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
||||.||...... .... .... .. |.|.|| ..|||. ||.|..|....||
RtGtfiaaylmleqlekelgvsleeavkelrsqRpgavqtpsqyrflyeallell
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 538-720 | 3.2e-45 | 149.2 | In-house | 4-185 (239) | alignment | ||
Range on Protein: 538-720
Range on HMM: 4-185/239.0
LEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYn
. ||.||||..||. |.|||| | |..| .|||||.|. |. ||. ..| || . . |.|||.|... .||||| |.| | |||.|||
kkrvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst.
pVTYGSIQVSVQALQQYDHWVIREFSISQG--DEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiqKTASDRPIVAHCSAGA
| ..|... . . ..|| | .|| | | . |||| |||.|||. . ..| . | . . || | |||||
.skycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkd..slpgarpwvihcsagv
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 539-719 | 4.4e-45 | 148.7 | In-house | 4-183 (239) | alignment | ||
Range on Protein: 539-719
Range on HMM: 4-183/239.0
EMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYnp
. ||.||||..||. |.|||| | |..| .|||||.|. |. ||. ..| || . . |.|||.|... .||||| |.| | |||.|||
krvnkaknryanivtydhsrvvleklsndphsdyinasylrdydgspkayiatqgcveissgdfwrmmwqerrcvivmltglieghkkkchqywpdst..
VTYGSIQVSVQALQQYDHWVIREFSISQG--DEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiqKTASDRPIVAHCSAG
| ..|... . . ..|| | .|| | | . |||| |||.|||. . ..| . | . . || | |||||
skycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkd..slpgarpwvihcsag
|
|||||||||
0040439 | (Phosphotyrosine protein) phosphatases II | 720-873 | 7.3e-45 | 148.9 | In-house | 93-247 (249) | alignment | ||
Range on Protein: 720-873
Range on HMM: 93-247/249.0
AIKCHEYWPAdYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVG
.||..||| ....|| ..| . ...|....|.. .. . .| |. ..... .|||||||. . ..|||.. ||.|.... .. |.. |||||||
rekcaqywpl.ggsleygdftvtllsvevkddytvrtleltnlydgesrtvlhiqytdwpdhgvppsfedlldfieavrkaleelpkggpvlVHCsaGvg
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
||||.||.. ... .... .|.. .....|.||...||.. ||.|..|....||.
RtGtfiaaylmleqlekelgvdleeavkllrsqRpgavqnpeqyrflyeallelll
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 721-869 | 1.3e-44 | 147.7 | Pfam-A | 82-234 (235) | alignment | ||
Range on Protein: 721-869
Range on HMM: 82-234/235.0
IKCHEYWP-ADYNPVTYGSIQVSVQ-ALQ-QYDHWVIREFSISQGDEI---RKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIqkTASDRPIVAHCSA
||..||| .. ...|||.|.| .. . . .....|...... .| |...|.|. .|||||||... .||..| |.. .|.. |.| ||||
ekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVM
|||||||..||| |.. ..... .|.. |..|.| ||..|||...||||......
GvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
Y_phosphatase | Protein-tyrosine phosphatase | 721-869 | 1.3e-44 | 147.7 | In-house | 82-234 (235) | alignment | ||
Range on Protein: 721-869
Range on HMM: 82-234/235.0
IKCHEYWP-ADYNPVTYGSIQVSVQ-ALQ-QYDHWVIREFSISQGDEI---RKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIqkTASDRPIVAHCSA
||..||| .. ...|||.|.| .. . . .....|...... .| |...|.|. .|||||||... .||..| |.. .|.. |.| ||||
ekcaqYwpeeeeesltygdikvelkekekedekeytlrklelkkkkeesekrevkqlhytnWpdhgvpespkslldlirkveksk..eaksgpvvVhCsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVM
|||||||..||| |.. ..... .|.. |..|.| ||..|||...||||......
GvgRtgtfvaldilleqleaeeevdvlqivkelRkqRpgmvqsleqYiflykail
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 519-720 | 1.4e-44 | 147.4 | In-house | 26-240 (300) | alignment | ||
Range on Protein: 519-720
Range on HMM: 26-240/300.0
TEEYDEIRLVGKDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDsDTDYINANYIPGY--NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVML
||..| .| . .| .| |||| ..||||..||.|.. .. .|.|||| | . |.....||||. || |.|.|.||.....||||
fteyeripkkredallstaklpenaeknrfkdvlPyednrvelsptken.stgyinassikvsvggkersyivaqgPleltvqdfWqmvWeqgvqlivml
TQLVEKGKIKCHEYWPAD---YNPVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASDR-
|. |.|| |...|.| . . |..| .|. . .. | . . . . | |.. .. |||||||| ..|.... |. .|| | .
teeeedgkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseve
------PIVAHCSAGA
|.. |||||.
skeskPPvlvhCsaGv
|
|||||||||
0037934 | (Phosphotyrosine protein) phosphatases II | 719-871 | 4.1e-44 | 146.3 | In-house | 86-241 (243) | alignment | ||
Range on Protein: 719-871
Range on HMM: 86-241/243.0
GAIKCHEYWPadyNPVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQK------TASDRPIV
|..||..||| ..|||| ..| . ...|....|..... .|. | ..||...|||||||| . .|||.. ||| |.. |..|..
grekcaqywp...gevtygdftvtllseehlddytvrtlllenldlddltrlvihyhylpwpdhgvPdspedlldfldevrefieellsllaldsggpvl
AHCSAGVGRTGTYIALDRLMQAMqenDyIDIFGIICEMRMQRNH-MVQTEKQYIFIHECVMDL
|||||||||||.||.. ... . . .|.. .....|.||.. .|||. ||.|..|... |
VHCsaGvgRtGtliaaylmllll...g.vdleeavkllreqRpgkavqtpsqyrflyeallel
|
|||||||||
subfamily_PTPN6_pd | Subfamily PTPN6 | 721-874 | 5e-44 | 145.5 | In-house | 138-299 (306) | alignment | ||
Range on Protein: 721-874
Range on HMM: 138-299/306.0
IKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSIS---QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTA--SDRPIVAHCSAG
|| |||. . .||.|.|. . .. .....||.|.| ...| |.. |||| |||||||| .. ..|||...|.. .... . .||| |||||
ekCarYWPdeeekeeyGkisvtnvseksladYilRelsvskkkkkkeerevfqyhfksWPdhgvpkdpgavLdfledvnrkqeeleeaeagpivvhCsaG
VGRTGTYIALDRLMQAMQEND---YIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
.|||||.| .| |.. .... ||| .. .| ||. .||||.|| |... . ...
iGRtGtfiviDillkliekkgldadidiqklvksvreqrsglvqteqqykfvykaikkyiet
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 502-720 | 1.9e-43 | 143.5 | In-house | 6-223 (439) | alignment | ||
Range on Protein: 502-720
Range on HMM: 6-223/439.0
KFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALE--MVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVD
.|. | ... . . |.|....| . | | ...| ...|||. .. ...|.|| | . . ||||||| || .. ..|.||| |.|
efqehvekldknkqeifkeifekinstspdyaciaslaaqeydqtknrykdvgafdhtrvtlqeipgvphshyinanyikGyyddklyiatqgpkkettd
DMWRMIWEKKTSIIVMLTQLVEKGKikcheYWPADYNpVTYGSIQVSVQALQQYDHWVIREFSIS----QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDF
|.||...||||. |||||.||| | |||.| . | || | | |. . ..||| | . ... | . |.|...|||. || .. .|||
dfwrlviekktvtivmltnlvesyk.....ywpsdae.vcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldf
VRTVREAIQKTASdRPIVAHCSAGA
.|.. | .| |.| |||||
lrainsandkeey.gpvvvhcsagv
|
|||||||||
subfamily_Nvec-PTP-2_pd | Subfamily Nvec-PTP-2 | 722-872 | 2e-43 | 143.4 | In-house | 92-242 (250) | alignment | ||
Range on Protein: 722-872
Range on HMM: 92-242/250.0
KCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRK--LTQYHFMSWPDHGVPDKTWTMLDFVRTVReAIQKTASDRPIVAHCSAGVGRT
..|.|||.. .. .||...||. ... ...|.. .|. . . . |.||..||| |||... ..|.... |. | |. | ..|.. .|||||||.
tyhqywPve.kaekyGdvtvsllskeefadytkrklklskakkaderivrqlhfvvWPdkgvPevatavLellkkvq.asqqqagnaPvivqCsaGvgrs
GTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
|..||.| ... .... .|.| .| .| .| |.|....||.|..| .. |
Gafiaidavlerlkkekvvdvfkvikvlrkdrphavesleqyvfvyeiilkal
|
|||||||||
subfamily_PTPN5_RR_pd | Subfamily PTPN5_RR | 722-873 | 2.1e-43 | 143.4 | In-house | 114-269 (274) | alignment | ||
Range on Protein: 722-873
Range on HMM: 114-269/274.0
KCHEYWPADYNP---VTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASD-RPIVAHCSAGVG
||..|.| . . .|| ... |. . ... .|...... . |... | . .|||| .||.. |.||.|. |.|. .... |.| |||||.|
kCavyfPdaedyeiserygdveikvekiverndysvrklvlkylerersvkhywytdWPdhksPddantlldlvleveesreeenaklapvvvhCsaGiG
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
||| .|| . .. ..|. .|...|.|..|..| ||||..|| .||. .. |.
rtGcfiaisiavrqlreeivvdvlkivcnlrldrGGmvqtseqyelihralclylk
|
|||||||||
subfamily_PTPN3_pd | Subfamily PTPN3 | 719-871 | 4.4e-43 | 142.2 | In-house | 122-274 (280) | alignment | ||
Range on Protein: 719-871
Range on HMM: 122-274/280.0
GAIKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqKTASDRPIVAHCSAGV
| .|||.||| . ..||...| .. .. .|.||. ... . | ||..| ...||||||||.. .|.||..||.. ......|.| |||||.
GrvkChqyWPetedeleygefsvkcekedetksyvlrelvlkdketkeerkilqlqylaWpdhgvPddsadflefvervrkl..rsgkeePvvvhCsaGi
GRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
|||| .|.|. .. ..... . . |. .|| || .|||..|| |. |... .
grtGvlilletalalieaaepvypldivrtmrdqramlvqtasqykfvCeailkv
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 536-720 | 8.5e-43 | 141.2 | In-house | 32-221 (287) | alignment | ||
Range on Protein: 536-720
Range on HMM: 32-221/287.0
SALEMVNRAKNRFTNILPYEHSRVKLAALAdDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADY
.| |. . |||....||....|| |.| . . .|||||||...|. .|.|.|||.. || |.||...|.... ....|. ||... ||..|||
aaeelaavkknryadvlPiddtrvllsaeg.elGsdyinanyvasytddeafiaaqgPiaatvrdfwravletrsasvitmtreveearlkcykywPere
NPVTYGSIQVSV--QALQQYDhWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVR---EAIQKTASDRPIVAHCSAGA
|. | | . . .. . . .| . . . . | | . |....||||.... . .. || |. |. .... |.| |...|.
vPmrvGGysvvlldydikePe.ygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhddvGi
|
|||||||||
subfamily_PTPRG_pd | Subfamily PTPRG | 721-882 | 9e-43 | 141.3 | In-house | 131-297 (563) | alignment | ||
Range on Protein: 721-882
Range on HMM: 131-297/563.0
IKCHEYWPAdYNPVTYGSIQVSVQALQQYD-----HWVIREFSISQGDE---IRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqKTASDRPIVAHC
||. |||. ...|||..|| .. .. . ||... . .... .. .|||. .|||||||... | ||. | . | ||| ||
rkcdvYWPk.desetygalqvtlieeevlalytvrtlviknlklkkkkqcdteklvrqyhytkWPdhgvPehslpvLifvkkssaa..nkaeaGPivvHc
SAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEEDTGE
|||||||||||.|| |.. .|... ...||.. .|.|||..|||| ||||.|. ...... .|.| . |
saGvgrtGtyivldtllkqiqqenavnvfgflkhiraqRnflvqteEqYiflhdalleaiasketellae
|
|||||||||
subfamily_Urchin-PTP-6_pd | Subfamily Urchin-PTP-6 | 721-872 | 1e-41 | 137.6 | In-house | 126-276 (515) | alignment | ||
Range on Protein: 721-872
Range on HMM: 126-276/515.0
IKCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTAsdRPIVAHCSAGVGRT
||| .||| . | .|||.|.. .|. ..|.. . .||..| .||.|| |||.||| .| ..| ... |. .. . |.. |||||||||
ikcgkyWPdkpgdsvkfGsikvelvsleactggikrkltvlkgddsrtvtqfhfteWPdkGvpkhtssllklikevkadhgqyt..hpliihcsaGvGrt
GTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
| .|..| . ... . .|.| .. .| .| ..|||. || ||.. |.. |
Gvvisidsvvahakttrmvdvfnfvtnirqkrpylvqtqeqyafiygavledl
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 518-720 | 1.6e-41 | 137.0 | In-house | 22-180 (392) | alignment | ||
Range on Protein: 518-720
Range on HMM: 22-180/392.0
FTEEYDEIRLVGKDQAiVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
|.||. .. . .| . .| |||. |||||. .|||| . | .|.||.|| |||.... . ..|.||| . ..||.|||....... |.|.|
ffeefhdlpgpdiypq.tvaqkeinlkknryknilpydsarvkleviddipdsdylnasyipsfdnekayiasqgpnaaslddfwrmvfqenvttiamvt
QLVEKGkikcheywpadynpvtygsiqvsvqalqqydhwvirefsisQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVReaIQKTASDRPIVAHCS
.| | .||. | .|.|| |||..||..| ..| |.. |. .. .|.. |||
klkegd.........................................kgddartvaqfhftewPdkdvpkhtssllkfikevk..adfGqythpliihcs
AGA
||
agv
|
|||||||||
subfamily_Ptp69D_pd | Subfamily Ptp69D | 722-877 | 2.8e-41 | 136.6 | In-house | 132-291 (307) | alignment | ||
Range on Protein: 722-877
Range on HMM: 132-291/307.0
KCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQGD-------EIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTasDRPIVAHCSA
||. ||| . . | ||.| | . .. ....|||...|. . . ||..|||...|.| ||. . ..|.... ||| .. ||| ||||
kcakYWpie.devqygdilvklvseekhsdyiiReldvskkkeesgevedsrkvvqyhytgWkDskvPevargllklieqvrelykln..rsPivvhCsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEE
||||.|...||| |.| ....| .||| .....| ||| .|| .||.|.. ..| |.
GvgrsgifvaldsllqqlkaedkvdifetvkdLrsqRnllvqsleqYvflyralldyssygdt
|
|||||||||
subfamily_Urchin-PTP-7_pd | Subfamily Urchin-PTP-7 | 722-876 | 8e-41 | 135.0 | In-house | 133-283 (315) | alignment | ||
Range on Protein: 722-876
Range on HMM: 133-283/315.0
KCHEYWPADynPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaiQKTASDRPIVAHCSAGVGRTGT
|. .||| . |.|| | |. . ...... .| .|. ||.||.. |.|. |||| ||| | ......|||. .|.| .|| |||||||||||
kaekywpdk..kviyGkitvtrkseevnteytvrtlsvvfgdnirevvqlhytswpdmgvpkytiplmnlirtvkq..hhtnsvgaivvhcsaGvGrtGt
YIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGE
.|.|| ... .. .. ||.. .| .| .| .|||. .|| ||.. ... . |.
fitldavldqaeaenaidvynfitgvrqnrikmvqvaeqyqfiydalletfvcgd
|
|||||||||
subfamily_PTPN13_pd | Subfamily PTPN13 | 719-873 | 9.2e-41 | 134.9 | In-house | 115-270 (273) | alignment | ||
Range on Protein: 719-873
Range on HMM: 115-270/273.0
GAIKCHEYWPADYN-PVTY-GSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaIQKtaSDRPIVAHCSA
| .||| ||| | ... . ..|.. .|..| .|.|.. .. . | |.... .|..||||||| .. .| ||. ||. .|. . ||| ||||
gkvkchrywPesknkklkvsnrlevellkvqkldgfvvralavkdsesgesrevahlnfvkwPdhgvPssaaellqfvaevrr.lqt..dagPivvhcsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
|.||.||.|..| ... .. . .|. |. ..| ||. .|||..||||... ....|.
GiGrsGtlitidvvlglierdkefdvkeivrklreqrqgvvqtkdqyifvykailevlk
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 536-720 | 1.1e-40 | 134.2 | In-house | 50-235 (297) | alignment | ||
Range on Protein: 536-720
Range on HMM: 50-235/297.0
SALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYnSPRE--FMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPA
| . | ||| ...|||.|||||| . |.....||||| | ||. ..|.||||. || |.|.|.||. . .||.||.| |.| .|..|||
vakaeknvkknrskavlpydhsrvklkeeasaeksdyinasaildh.dprapayiatqgplastvadfwqmvweqGvvvivnltrleeegvkqckrywpd
DYNPVtYGSIQVSVQAL-QQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASdrPIVAHCSAGA
. . | |. .| . . | ...| | . | .| | .||.||.|||..||| .. ..|.| | | . . .. ||| |||.||
eGsev.yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrsc..pivvhcsdGa
|
|||||||||
subfamily_PTPRK_pd | Subfamily PTPRK | 720-871 | 1.5e-40 | 133.9 | In-house | 125-276 (314) | alignment | ||
Range on Protein: 720-871
Range on HMM: 125-276/314.0
AIKCHEYWPADYNPvtYGSIQVSVQALQQYDHWVIREFSISQ----GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKtaSDRPIVAHCSAG
..|| .||| | . || |.| . . |.| |.... .|||.. |..|..||||.|| . ..|..|| | . .. .. .|| |||||
rvkClkyWPedtev..ygdikvelvetellaelvvrifrveklargqeeirevrqfqflgWpdhdvPvsatgllklvrrvkksqee..eaGrivvhCsaG
VGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
|||||.||.| ... ..... .|.| .. ..| .. ||.||.||.||.. ...
aGrtGtfiaidivldmieregvvdvfnavktlrsrkvnmveteeqykfiydvilea
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 540-722 | 2.4e-40 | 133.5 | In-house | 45-242 (418) | alignment | ||
Range on Protein: 540-722
Range on HMM: 45-242/418.0
MVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGyNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP--
| .|||.||||| .|.||.| . | .|||||||| | |..|.. ||||| |. |.|||.||.. |||||.. |. .||| ||| .
khntsknrytnilpvnhtrvqlkkiqdkegsdyinanyidg.aypkqfictqgplpntiadfwrmvwenrcriivmlsresencrikcdrywpeqiggeq
--------VTYGSIQVS-VQALQQYDHWV-IREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTV--REAIQKTASDR--PIVAHCSAGAIK
.|. | |. .|. .. . |. .. | | .|||.. |||| .|..| . ...... |. .||| ||. ||||| .
fsiygngnevfgtysvelveviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgr
|
|||||||||
subfamily_Urchin-PTP-1_pd | Subfamily Urchin-PTP-1 | 721-873 | 3.6e-40 | 132.7 | In-house | 127-278 (315) | alignment | ||
Range on Protein: 721-873
Range on HMM: 127-278/315.0
IKCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqKTASDRPIVAHCSAGVGRT
||| ||| . . | .|||.|.. |.. |.|.. . ...| |..||..| |||.||. .| ..| ... |. . . ... |||||||||
ikcrqywPdrkadsvefGsikvellsleadtdgvarklvtrkseesrtvtqfqftewPdkGvdkqtssllklikevkad..ngkkefsllvhcsaGvGrt
GTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
| |..| .. ..... .|.| .. ..| .| ..||||..| ||.. |.. |
Gvvisidevvaqikrtrsvdvfnfvknlrakrpylvqteeeyafiydavledll
|
|||||||||
subfamily_Urchin-PTP-5_pd | Subfamily Urchin-PTP-5 | 722-874 | 9.6e-39 | 128.3 | In-house | 132-286 (297) | alignment | ||
Range on Protein: 722-874
Range on HMM: 132-286/297.0
KCHEYWPaDYNPVTYGSIQVSVQALQQYDHWVIREFSISQGD--EIRKLTQYHFMSWPDHGVPD--KTWTMLDFVRTVREAIQKTASDrPIVAHCSAGVG
|| ||. | .|.|.. | ...... . ||.....|. | . ||.|..|||. |. .. ..|... ||. ...|. |.. ||.||||
kcaryWs.dkgvttfGdvsvvllsvsereGfikrelevtkgkakarrvvkqyqfveWPdkaverkdsassllklisevrkdfsqnaeg.PllvhclaGvG
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
||| ....| . ..... .||||.. .| .| ..|||..|| |... |.. |
rtgvlltidsvvaeakrekevdifglvkklrqerpylvqtkeqykfvyvavlealls
|
|||||||||
subfamily_PTPN9_pd | Subfamily PTPN9 | 719-871 | 1.8e-38 | 127.3 | In-house | 123-289 (297) | alignment | ||
Range on Protein: 719-871
Range on HMM: 123-289/297.0
GAIKCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQ-----------KTAS
| .|| .||| . . .|...||. ........| . |. . .|.||.| . |.||||.|||. . ..||....|||. .|
grlkcgqyWpleeessaefgdlsvsnveveeeedykvrvleiknvkteesrkvthfqflsWPdyGvPssaaslldvlekvrekqalavkelgdewkghps
DRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
. ||| |||||.|||||.|.|| .. ..| . .|.. . .| || ...||..|| | . .|..
gPPivvhcsaGiGrtGtfitldiclsrleevgtvdvvetvkllrtqrafsiqtpeqyefcylavley
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 537-720 | 4.5e-38 | 125.6 | In-house | 37-234 (296) | alignment | ||
Range on Protein: 537-720
Range on HMM: 37-234/296.0
ALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKiKCHEYWPADYn
.|. || ||| ...||.. || | | ....||||| |. .. ..|.. ..| |||. ||.......| .|.||. . | ....||| .
glrkenreknrdvkvvPyDynRvvLekldGeeksdYinavyvdsflkkkeyivteapkketvdefWrlvydeeisavvvLtktfdfak.mypsywpnks.
PVTYGSIQVSVQALQQYDHWVIREFSISQG------------DEIRKLTQYHFMSWPD-HGVPEKTWTMLDFVRTVREAIQKT---ASDRPIVAHCSAGA
|| | | . .|| . .||.| . . | | ...... |. . || | ......| || ..|. |.| ..| ||
keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpeegPvvvvssdGa
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 720-873 | 1.3e-37 | 125.3 | In-house | 60-226 (272) | alignment | ||
Range on Protein: 720-873
Range on HMM: 60-226/272.0
AIKCHEYWP-----------ADYNPVTYGSIQVSVQALQQYDHWVIREFSIS---QGDEIRKLTQYHFMSWPDHGVPDKTwtMLDFVRTVREaiqktasD
. ||. ||| .. ...|| . | .. ........||. .. . .|.|.....|...|||||||... .|.... ... .
rlkcdrywpgirylhlpilddsaptilygalrvtllseellldyilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.......g
RPIVAHCSAGVGRTGTYIALDRLMQAMQENDYID--------IFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
.|.. |||||..||||..||..|.. . ... .| ..... |.| || ..|||| ||.|..|....|||
gpvlvHCsaGkdRTGtvvallllllgvsletivddYlltnlyleeaveelraqrpgavqteeqylflyeallellr
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 517-719 | 1.4e-37 | 124.1 | In-house | 16-236 (301) | alignment | ||
Range on Protein: 517-719
Range on HMM: 16-236/301.0
RFTEEYDEIRLVGKDQAIVSALEmVNRAKNRFTNILPYEHSRVKLAAL--ADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIV
.| |.|.|.. . .....|. | |.| ||| || .|.. |. |. | . ..||||.|| ||.. ..|.| |||. |. |.||.||..|.. ||
kfeeqykelkegedksctvglse.enkalnrfknitvyddnriilkpkpnldlcqreyinasyidgysekkkfiaaqgpmkktlvdfWrliwqekpvsiv
MLTQLVEKGKIKCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFSI-----------------SQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFV
|.|.| |. | ||..||| . . ..| ..| .. | | .|||.... .. . ....|.. .||..|| |.| .
mvtnlkegtkskceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqvi
RTVREAIQKTaSDRPIVAHCSAG
| . || . |.| |||..
ddvihrqqki.gggpvvVHCSdt
|
|||||||||
subfamily_Urchin-PTP-3_pd | Subfamily Urchin-PTP-3 | 722-888 | 4.2e-37 | 123.0 | In-house | 131-304 (325) | alignment | ||
Range on Protein: 722-888
Range on HMM: 131-304/325.0
KCHEYWPAD-YNPVTYGSIQVSVQALQQYDHWVIREFSISQG--DEIRKLTQYHFMSWPDHGVPDKTWTMLD---FVRTVREAIQK-TASDRPIVAHCSA
.| ||| . . .|.|...|........ .| | . . | | | . |....||.| ||. . |.. | .| | .. | . ||. ||||
rcavywpkemgksktfGglevklrtieeisdyvhrvldvkqvkkGetrsvkqfqlqswddmGvqkrpatlisilqlvkavservtantkastpilvhcsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEEDTGESIYVNL
||||||..|.| ... . |. .|||| . .| .| ||.| |||.|.|.... . |. . |. .|
GvGrtGvfislysalakvieesrvdifgfvkklrkdrpsmvetvdqyiliyealveaymsgntdvpvssfeakl
|
|||||||||
subfamily_Choan-PTP-2_pd | Subfamily Choan-PTP-2 | 721-871 | 1.1e-36 | 121.3 | In-house | 104-263 (270) | alignment | ||
Range on Protein: 721-871
Range on HMM: 104-263/270.0
IKCHEYWPADYNP---VTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTW------TMLDFVRTVREAIQKTASDRPIVAH
|| ||||. . ...| |.| ... .. . ..... . . |.|.|. ... .||||||| .. .| .|.||. .... |.. |
kkCerYWpaepkekvkledgkikvlalseekeegyiltrlrleekgeerrlvHfwyntWpdhgvpreedsslstdqllkmlravrrsekeldkaePllvH
CSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
|||||||||| |||| .....|. .|. || |.| .| .||. .|| |... |.
csaGvgRtGtlialDiavrlLeetkkvdvlaiieelRkdRmalvqhpeqyeflykavvey
|
|||||||||
PTPc_DSPc_SM00012 | 768-869 | 1.9e-36 | 119.8 | In-house | 2-104 (105) | alignment | |||
Range on Protein: 768-869
Range on HMM: 2-104/105.0
LTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVGRTGTYIALDRLMQAMQEN-DYIDIFGIICEMRMQRNHMVQTEKQYIFIHE
...||...|||||||... .|...| |.. .| .| |.| |||||||||||..||| |.| .... . .||| |..|.|.||..||||| ||.|...
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGvgRtgtfvaldillqqleketkevdifqivkelrkqRpgmvqteeqylflyr
CVM
...
all
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 520-719 | 3e-36 | 119.8 | In-house | 13-209 (283) | alignment | ||
Range on Protein: 520-719
Range on HMM: 13-209/283.0
EEYDEIRLVGKDQAIVSAleMVNRAKNRFTNILPYEHSRVKLAALADdsdtDYINANYIP---GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVML
| .... . .| | || |. |||. .|.|.. ||.| ... ||||| .|| |. ......|.|| || |.|.|....| . ||||
evlkrlsvpdldadiasa..denkrknrnqeivpadqwrvelksesr....dyinavfipvsksykqdkkyiiaqsPldrtvvdfWkmvfdekitaivml
TQLVEKGKIKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQG---DEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVreAIQKTASDRPIV
|.| | .||| ||| . . || |... . ..|.|. . . . |. | . | . | ... | . . . |. . |||
tklqedlrikCsqyWPkr.GsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvi..slqteskkgPiv
AHCSAG
|||.|
vhCstg
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 542-719 | 3.1e-36 | 120.0 | In-house | 1-119 (182) | alignment | ||
Range on Protein: 542-719
Range on HMM: 1-119/182.0
NRAKNRFTNILPYEHSRvklaaladdsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTqlvekgkikCHEYWPadynpvtyg
|. |||...||||.||| | ||||||.. |. ...| |.||||..|| |..||..| . ..||.|| .. |||
nldknrysdilpydhsr..........dldyInanlylgslpatrfiatqgpllstvadflrmlkelgittivnlt.........eelywp.........
siqvsvqalqqydhwvirefsisqGDEIRKLTQYHFMSWPDHGVPEkTWTMLDFVRTVREaiqktaSDRPIVAHCSAG
.. | .||....|||||||. . ..|||...|.| ...|.. |||||
........................ellerlgiqylylpwpDhgvpd.ldelldfieevle......eggpvlVHCsaG
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 530-692 | 9e-36 | 118.2 | In-house | 21-186 (297) | alignment | ||
Range on Protein: 530-692
Range on HMM: 21-186/297.0
KDQAIVSALEMVNRAKNRFTNILPYEHSRVKLAALAddSDTDYINANYI--PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKC
. .. || |||...|| .. .|||| ...|||||.|. | ... .. |||| |||| |....|. .|||...| | |. ||
rgesfssakrnsslrknryrdilatddtrvkllrvi..terdyinadyvvfpdeeadlkyilaqGplsatvddfwtlvaeqdvrvivmvaklqedGrdkc
HEYWPA-DYNPVTYGSIQVS--VQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTM
||| . . . |.. | . ...|. .. |. . .| |... |.|||||||| .
apywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdledl
|
|||||||||
0051429 | (Phosphotyrosine protein) phosphatases II | 570-719 | 4.3e-35 | 117.0 | In-house | 4-160 (272) | alignment | ||
Range on Protein: 570-719
Range on HMM: 4-160/272.0
TDYINANYIPGYNS---PREFMACQGPLPGTVDDMWRMiWEKKTSIIVMLTQLVEKGKIKCHEYWP-----------ADYNPVTYGSIQVSVQALQQYDH
..||||....||.. |. . ...|||| |..| ||. .| . . ||.|....|.|. ||. ||| .. ...|| . | .. .....
sgyiNardvggygrvvkpgrlyrsggplpltaadfwrl.kelgiktivdLrseeErgrlkcdrywpgirylhlpilddsaptilygalrvtllseellld
WVIREFSIS---QGDEIRKLTQYHFMSWPDHGVPEKTwtMLDFVRTVREaiqktasDRPIVAHCSAG
...||. .. . .|.|.....|...|||||||... .|.... ... ..|.. |||||
yilrellltlllsagearevmhlhytdwpdhgvpqea..llellellld.......ggpvlvHCsaG
|
|||||||||
subfamily_Anemone-PTP-4_pd | Subfamily Anemone-PTP-4 | 721-869 | 6.8e-35 | 115.4 | In-house | 85-236 (237) | alignment | ||
Range on Protein: 721-869
Range on HMM: 85-236/237.0
IKCHEYWPADYNPVTYGSIQVSVQALQQYDHWVIREFSISQ---GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGVG
.|||.||| .| .|| . ||.. ... . .| . .|. |.| . ||.| ||||.|||..| ..| | . . . .. . | . |||||||
lkchkywpstdqpaaygvltvslkkkeefsdytvrslllskrltlkevrlihqyqftswpdrgvpqqtaallrfrkniinrsphvsesgpwiihcsagvg
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVM
||| .. .| ... .|. .||. . . .| ...||. ||.|||. ..
rtgiflvidamlrqakekkvvdiynyvysieedrpyiiqtkdqyvfihqtil
|
|||||||||
subfamily_Sponge-PTP11_pd | Subfamily Sponge-PTP11 | 719-874 | 1.4e-34 | 114.3 | In-house | 129-285 (290) | alignment | ||
Range on Protein: 719-874
Range on HMM: 129-285/290.0
GAIKCHEYWPADYNPVtYGSIQVSVQALQQYDHWVIREFSISQGDE---IRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaIQKTASDRPIVAHCSAG
| ||. |||. . || ... .. ..... ..|.... . .. ...|||.. .|...| .. |.| .. . . .|. ...|| |||..
gkvkCqqYWpdsdtka.ygefsikllneetlneyierklevknknsagakqsvtqyqitnwdstgkvtnpqtillvieemyk.tqrkrgntsivvHCSdt
VGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
|||.....|.. .. .. . ||.| .. ..|.|. .|||..|| .|.. |. | .
vgrsavfcaaattinkcktegvidvfqvlksqRiqkpgsvqtvqqyqgifqivltylds
|
|||||||||
subfamily_Sponge-PTP6_pd | Subfamily Sponge-PTP6 | 722-875 | 3.9e-34 | 112.8 | In-house | 127-282 (439) | alignment | ||
Range on Protein: 722-875
Range on HMM: 127-282/439.0
KCHEYWPADYNpVTYGSIQVSVQALQQYDHWVIREFSIS----QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASdRPIVAHCSAGVG
. . |||.| . | || | | |. . ..||| | . ... | . |.|...|||. || .. .|||.|.. | .| |.| |||||||
esykywpsdae.vcygdiavrvdrnielpnyvirgfkvfnerdttekertvlqfhyiawpdknvpaqashvldflrainsandkeey.gpvvvhcsagvG
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRG
|||| |||| .. .. .. .|| ||. .| ||..|||. ||.||...|.. . |
rtGtiialdialeqlklenkvdikgivkvlrkqrkqmvqalcqyvfiynavledivyG
|
|||||||||
subfamily_Sponge-PTP10_pd | Subfamily Sponge-PTP10 | 721-874 | 7.6e-34 | 112.0 | In-house | 126-280 (287) | alignment | ||
Range on Protein: 721-874
Range on HMM: 126-280/287.0
IKCHEYWPADYNpVTYGSIQVSVQALQQYDHWVIREFSISQGD---EIRKLTQYHFMSWPDHG-VPDKTWTMLDFVRTVREaiQKTASDRPIVAHCSAGV
.|..||| . . |..| .... ........|.. . . . . ....||.. .|...| |... .| . . ... |. .. .|| |||..|
evcyqyWpeeks.vvlGeyniellneevnagyierklevknknkagdkqqvkqyqitnWdstgkvtepqtillvieemykt..qrkrgntsivvhCsdtv
GRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
||.....| . .. ... ||.| .. ..|.|. ..||| .||.|| . |. |
GrsamfcaaattinkckteGviDvfqvlksqriqkpgsvqtveqykfindivleylds
|
|||||||||
subfamily_Nvec-PTP-1_pd | Subfamily Nvec-PTP-1 | 722-870 | 7.8e-33 | 108.6 | In-house | 92-238 (239) | alignment | ||
Range on Protein: 722-870
Range on HMM: 92-238/239.0
KCHEYWPADYnpVTYGSIQVSVQALQQYDHWVIREFSISQG--DEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqKTASDRPIVAHCSAGVGRT
|||.||| | ..|... . . ..|| | .|| | | . |||| |||.|||. . ..| . | . . || | |||||||||
kchqywpdst..skycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkd..slpgarpwvihcsagvgrt
GTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
|... .| ... ... .||| . .| .| ||||| .||.||| .|..
gaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavle
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 544-719 | 9.2e-33 | 108.1 | In-house | 58-226 (290) | alignment | ||
Range on Protein: 544-719
Range on HMM: 58-226/290.0
AKNRFTNILPYEHSRVklaALADDSDTDYINANYIPGYNSPreFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADY-NPVTYGS
|||. .. . .|| | | | ||. |||. | ... |. ||.| || |.|||. ..|.. |||| .|.|.|| ||..|.| . .|.|.
kknrykdvvcndktrv...ilkdGydGdyvhanyvkGlkam..filtqGalkdtvidiwrmvlqekvaaivmlceliedGkakceqyypekeGevltfGe
IQVSVQALQQYDHWV-IREFSISQGDE--IRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiqktasDRPIVAHCSAG
| | .. | . . .|. . |. || .. .||||. |. | ..| .|..|.| |.| |||||
itvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka......sGpvvvhcsaG
|
|||||||||
subfamily_Anemone-PTP-1_pd | Subfamily Anemone-PTP-1 | 722-869 | 9.7e-33 | 108.3 | In-house | 93-238 (239) | alignment | ||
Range on Protein: 722-869
Range on HMM: 93-238/239.0
KCHEYWPADYnpVTYGSIQVSVQALQQYDHWVIREFSISQG--DEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqKTASDRPIVAHCSAGVGRT
|||.||| | ..|... . . ..|| | .|| | | . |||| |||.|||. . ..| . | . . || | |||||||||
kchqywpdst..skycnlrvtlrktevfadyiirtfvmsqvgqteeryvyqyhftvwpdkgvpqyatavlglrrkitkd..slpgarpwvihcsagvgrt
GTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVM
|... .| ... ... .||| . .| .| ||||| .||.||| .|.
gaflvidamlrqakkqktvdifnyvkairedrphmvqtseqyvfihlavl
|
|||||||||
subfamily_PTPN23_pd | Subfamily PTPN23 | 721-874 | 1.6e-32 | 107.5 | In-house | 123-282 (288) | alignment | ||
Range on Protein: 721-874
Range on HMM: 123-282/288.0
IKCHEYWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVRE--AIQKTASDRPIVAHCSAG
|...|||.| ..|..| ..|... .. ...| |..... . |...... ...|||..|||. |.|.|. |.. .. |. |.| |||||
pkvdrYwPedkgetvkfgdlsvtlksvretethvervlkletldadavksvshlqltsWpelGvPasPetllqfldevesayeavqrksktPlvvhCsaG
VGRTGTYIALDRLMQAMQEN-DYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
|||||.. . ....... .|| .. .| || .|||...|. | | |. ||
vgRtgvfalvyaavrelekgnglldiiqvvsrlreqRrfmvqekeqlkfsyeavleaarr
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 539-720 | 6e-32 | 105.4 | In-house | 34-211 (281) | alignment | ||
Range on Protein: 539-720
Range on HMM: 34-211/281.0
EMVNRAKNRFTNILPYEHSRVKLAA-LADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADY-N
. || |||..|| . |||.| . . |||| |||| | .. ||| | |.|||||...|. |||| |..| . || ||.| .
qpvnnkknrylnipcldisrvqlkvkmpnknstdyihanyirspflkrgyiltqgpkketradfwrmiwqenttaivmlcqfletnrekcaeyfprnahc
PVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVReaiqktASDRPIVAHCSAGA
. . . || . | . .| | | .|.. . ||| ||| . || .| .| | | | |||||
clqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkir......arstppvihcsagv
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 722-866 | 7.7e-32 | 105.8 | In-house | 53-164 (174) | alignment | ||
Range on Protein: 722-866
Range on HMM: 53-164/174.0
KCHEYWPAdynpvtygsiqvsvqalqqydhwvirefsiSQGDEIRKLTQYHFMSWPDHGVPDKTWtMLDFVRTVREAIQKtASDRPIVAHCSAGVGRTGT
||. ||| . |. | ||... |||||||| . .|.||. |.||... ...|.. |||||||||||
kcinywpe..............................lredlerlgiqylylpwpDhgvpdlsi.llefvkfveealse.dpggpvlVHCsaGvgRtGt
YIALDRLMQAMQeNDYIDIFGIICEMRMQRNHMVQTEKQYIFIHE
.|...... . ....|.. .. |.|.|| .||||. ||.|...
lvaaylmlrgll.eslvdaldlvrelRlqrpgmvqtpsQyrflyy
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 533-704 | 7.8e-32 | 105.2 | In-house | 17-195 (319) | alignment | ||
Range on Protein: 533-704
Range on HMM: 17-195/319.0
AIVS--ALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYN-SPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHE
| . .. . . |.|. |..| ..|| | .|| . |..|.|. ||. .| ..|.| .| . |.||..||... .|| ||.| |.| .| |
liaradevPvtskdksrvinvvPlPetrvvlqrigdddkdeyldasyvrGyddapnsyiaaqvsledsssdfwrtvweqqsrvivqltdlselGikvcae
YWPAD---YNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFmSWPDHGVPEKTWTMLDFVRTVREAIQ
|.|. | .|| |.|... . |...| . . ...| |.|| | . |.. .|| . ... . ||....
ylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaeeaaliamllevrsslk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 532-719 | 3.8e-31 | 104.4 | In-house | 36-222 (314) | alignment | ||
Range on Protein: 532-719
Range on HMM: 36-222/314.0
QAIVSALEMVNRAKNRFTNILPYEhSRVKLaALADDSDTDYINANYIPGYnspREFMACQGPLPGTVDDM----------WRMI--WEKKTSIIVM----
. |. | .|| |||...|||.. .||.| . |..|||||.|. |. . |.|.||||. ||.| |||. .. .. .|||
ltilvadlflnrdknryldilpad.nrvil.pglpvsgsdyinasyvdgf...lkfIatqgpleitvvdfreepvlyyngwrmvlrgdlnvrdivmsrde
-----------------LTQLVEKGkikcHEYWPADYNPVTygsiqvsvqalqqydhwvirefSIS--QGDEIRKLTQYHFMSWPDHGVPeKTWTMLDFV
|..| ..| |...||. .. . . | .|. . .||...| . ...|.
vladelsrLdaAlgKtpllildgng....neptaadlellk......................eelydpelferlgikylripvpDgsap.lledfdefl
RTVREAiqktASDRPIVAHCSAG
. ..|| ..|.. ||.||
efieea....dkggpvlvHCkaG
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 524-719 | 3.6e-30 | 100.0 | In-house | 21-219 (307) | alignment | ||
Range on Protein: 524-719
Range on HMM: 21-219/307.0
EIRLVGK---DQAIVSALEmVNRAKNRFTNILPYEHSRVKLAalADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLV
|.| . | . | |.. | |||.... ...|. . | .||| |||. |. |...|||| |. ..| |. ..| ..|| ...
efrvlakktpegvtveafs.antdknryqdvkcqdkgrivvk..fdglasdyihanylgiaikpkkficaqgplentqysfwamaiqekvesvimlckvi
EKGKIKCHEYWPADY-NPVTYGSIQ--VSVQ-----ALQQYDHW-VIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREaiqktaSDRP
| .||||..|||.. . ..|. .||. | .. . .. . ... | .... . |||.|||. | .... .|| |
elakikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry......dtnp
IVAHCSAG
.| |||||
vvvhcsaG
|
|||||||||
subfamily_PTPRN_pd | Subfamily PTPRN | 720-870 | 4.1e-30 | 99.5 | In-house | 139-290 (297) | alignment | ||
Range on Protein: 720-870
Range on HMM: 139-290/297.0
AIKCHEYWPADYNPVtYGSIQVSVQAL-QQYDHWVIREFSIS--QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASdrPIVAHCSAGV
.|..||| . . | |. .| . . | ...| | . | .| | .||.||.|||..||| .. ..|.| | | . . .. ||| |||.|.
vkqckrywpdeGsev.yhiyevhlvsehiwcddylvrsfylknlqtsetrtvtqfhflswpeegvPasaksllefrrkvnksyrGrsc..pivvhcsdGa
GRTGTYIALDRLMQAMQE-NDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
||||.||..| ... .. ||| . .| ||...|.|..|. |. .| .
GrtGvyilidlvlnrllkGvkeidiaatlehlrdqrpglvktkdqfefaltavae
|
|||||||||
0036282 | (Phosphotyrosine protein) phosphatases II | 570-719 | 7.8e-30 | 99.2 | In-house | 2-114 (174) | alignment | ||
Range on Protein: 570-719
Range on HMM: 2-114/174.0
TDYINANYIPGYNSPREFMACQGPLPgtvddMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAdynpvtygsiqvsvqalqqydhwvirefsiSQGDEI
.|||||... .. .... |.||||. |.|..| . ...|||....|.|. ||. ||| . |.
sdyinaspldlsyitprliagqgpla.....fwemlkelgittvvmlleekelglykcinywpe..............................lredle
RKLTQYHFMSWPDHGVPEKTWtMLDFVRTVREAIQKtASDRPIVAHCSAG
| ||... |||||||. . .|.||. |.||... ...|.. |||||
rlgiqylylpwpDhgvpdlsi.llefvkfveealse.dpggpvlVHCsaG
|
|||||||||
subfamily_PTPN14_pd | Subfamily PTPN14 | 719-874 | 1.7e-29 | 97.8 | In-house | 131-298 (300) | alignment | ||
Range on Protein: 719-874
Range on HMM: 131-298/300.0
GAIKCHEYWPAD---YNPVTYGSIQVSVQALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDR-------
| |...|.| . . |..| .|. . .. | . . . . | |.. .. |||||||. ..|.... |. .|| | .
gkeksfkyfPkleskkktvefgkfkvttkfsedsdsvittglklkhlpskeertvwhlqytDWpdhgvPeDvkgflsyLeevqsvrrktnseveskeskP
PIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
|.. |||||||||| | | |..... |. ||| .. .| || ..||| || |... .. |..
PvlvhCsaGvGrtGvlilsdlliatlehneeidikkvlarLreqrmllvqtlaqYkfvYkvlikylkn
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 741-871 | 1.8e-29 | 97.7 | In-house | 20-142 (145) | alignment | ||
Range on Protein: 741-871
Range on HMM: 20-142/145.0
VSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKtasDRPIVAHCSAGVGRTGTYIALDRLMQamqeNDyIDI
.... |...... . .. . .. |. .||....|||||||| . ..|.|.. ..||... ..|.. |||||||||||..|.. ... .. ...
ldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealke...ggpvlVHCsaGvgRtgtlvaaylmll....lg.vsl
FGIICEMRMQRNHMVQTEKQYIFIHECVMDL
. .. ..|.|| ..|... |..|..|... |
eealelvrsqrpgavpnpgqlrflyefelel
|
|||||||||
0041856 | (Phosphotyrosine protein) phosphatases II | 723-874 | 2.3e-29 | 97.7 | In-house | 67-173 (182) | alignment | ||
Range on Protein: 723-874
Range on HMM: 67-173/182.0
CHEYWPadynpvtygsiqvsvqalqqydhwvirefsisqGDEIRKLTQYHFMSWPDHGVPDkTWTMLDFVRTVREaiqktaSDRPIVAHCSAGVGRTGTY
.. ||| .. | .||....|||||||| . ..|||...|.| ...|.. |||||||||||.
eelywp.................................ellerlgiqylylpwpDhgvpd.ldelldfieevle......eggpvlVHCsaGvgRtgtl
IALDrLMQAMqenDyIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
.|.. || . . .... .....|..|..||.|. ||.|.. ....||..
vaay.lmkkl...g.vsleeavklvrsrRpgmvitpnqyfflqlallellll
|
|||||||||
subfamily_PTPN1_pd | Subfamily PTPN1 | 720-870 | 2.5e-29 | 96.9 | In-house | 110-269 (290) | alignment | ||
Range on Protein: 720-870
Range on HMM: 110-269/290.0
AIKCHEYWPADYN--PVTYGSIQVSV--QALQQYDHWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTASDRPIVAHCS
|||..||| . . ... ....| . ........| . . . .| |.....|...||| |||. ..|.|. |||. . | | |||
qikcaqywPqgeeekellledtklkvkliseerksyytvrllelenlktqetreilhfhyttwpdfgvpespaaflkflfkvresGslssdvGpavihcs
AGVGRTGTYIALDRLMQAMQENDY---IDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
||.||.||.. .| .. ....| .|| ..|.| .| ..|| .| | . ...
aGiGrsGtfclvdtclvliekkddlssvdikkvllelrkyrlGliqtadqlrfsylaile
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 565-719 | 3.7e-28 | 93.9 | In-house | 7-119 (176) | alignment | ||
Range on Protein: 565-719
Range on HMM: 7-119/176.0
ADDSDTDYINANYIPGYnsprEFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTygsiqvsvqalqqydhwvirefsis
.| | ||||||.| |. . |.|||||.|. | ..|..| . ...|.||..||.|..||. ||| ...
gldldldyinanlilgs....rpiatqgplprtladflemlkelgitavvnlteevelgrlkcpnywpeleklgi.........................
qgdeirkltQYHFMSWPDHGVPEKtWTMLDFVRTVREAIQKTasdRPIVAHCSAG
||... |||||||. .|.... .|||... .|.. |||||
.........qylhlpwpDhgvpdl.elllellefirealkeg...gpvlVHCsaG
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 567-719 | 4.3e-28 | 93.6 | In-house | 2-110 (172) | alignment | ||
Range on Protein: 567-719
Range on HMM: 2-110/172.0
DSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLvekgkikcheywpadynpvtygsiqvsvqalqqydhwvirefSISQG
|...|||||.|...| |..| |.||||. |..| |||..|.. ..||.||.|
degsdyinasyldlyyipdrfiatqgplrntladfwrmlkelgithivnltel..........................................lydpe
DEIRKLTQYHFMSWPDHGVPeKTWTMLDFVRTVREAIqKTASDRPIVAHCSAG
.. | ||....||||||| . .|.|.. ..|.. .. |.. |||||
llerlgiqylylpwpDhgvp.llellleflefidell.alspggpvlVHCsaG
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 758-876 | 9e-28 | 91.8 | In-house | 81-198 (440) | alignment | ||
Range on Protein: 758-876
Range on HMM: 81-198/440.0
SISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiQKTASDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQT
| .| | | | |||. .|||.||| . .| ... | |. |. |.. |.. |||||.|||| ||.| ... . .| |||| .| || .| .||||
syingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnes.qekagngpllvhcsagagrtgviiavdsilreakrsdqidifsfinsmrnnrpqmvqt
EKQYIFIHECVMDLLRRGE
.|| |.||.|.. | |.
peqyafvheavlegllcgd
|
|||||||||
0046846 | (Phosphotyrosine protein) phosphatases II | 722-872 | 1.2e-27 | 92.2 | In-house | 64-173 (176) | alignment | ||
Range on Protein: 722-872
Range on HMM: 64-173/176.0
KCHEYWPADYNPVTygsiqvsvqalqqydhwvirefsisqgdeirkltQYHFMSWPDHGVPDKtWTMLDFVRTVREAIQKTasdRPIVAHCSAGVGRTGT
||. ||| ... ||... |||||||| .|.... .|||... .|.. |||||.|||||
kcpnywpeleklgi..................................qylhlpwpDhgvpdl.elllellefirealkeg...gpvlVHCsaGigRtgt
YIALDrlmqAMQENDYIDIFGIICEMRMQRN-HMVQTEKQYIFIHECVMDLL
..|.. .. . .... .....|.|| ..|||..|| |..|... ||
lvaay....llelekglsveealalvreqRplgavqtpeQyrflyefellll
|
|||||||||
0043147 | (Phosphotyrosine protein) phosphatases II | 762-867 | 1.6e-27 | 91.7 | In-house | 59-156 (172) | alignment | ||
Range on Protein: 762-867
Range on HMM: 59-156/172.0
GDEIRKLTQYHFMSWPDHGVPdKTWTMLDFVRTVREAIqKTASDRPIVAHCSAGVGRTGTYIALDRLMqamqenDYIDIFGIICEMRMQRNHMVQTEKQY
.. | ||....||||||| . .|.|.. ..|.. .. |.. ||||||||||| .|.. .. .... .....|..|...||.. ||
ellerlgiqylylpwpDhgvp.llellleflefidell.alspggpvlVHCsaGvgRtgtlvaaylml......lglsleeavalvrekRpgavqnpsqy
IFIHEC
.|....
rflyyf
|
|||||||||
subfamily_Urchin-PTP-4_pd | Subfamily Urchin-PTP-4 | 746-872 | 1.9e-27 | 90.7 | In-house | 122-237 (392) | alignment | ||
Range on Protein: 746-872
Range on HMM: 122-237/392.0
LQQYDhwvirefsisQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVReaIQKTASDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIIC
|.. | .||. | .|.|| |||..|| .| ..| |.. |. .. .|.. |||||||||| |..| .. .. .|.| ..
lkegd..........kgddartvaqfhftewPdkdvpkhtssllkfikevk..adfGqythpliihcsagvgrtgvvisidsvvahakktrmvdvfnfvt
EMRMQRNHMVQTEKQYIFIHECVMD-LL
..| .| .||||..|| ||. .|.. ||
nirrkrpymvqtkeqyafiygavledll
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 539-720 | 2.4e-27 | 90.5 | In-house | 45-230 (305) | alignment | ||
Range on Protein: 539-720
Range on HMM: 45-230/305.0
EMVNRAKNRFTNILPYEHSRVKLaalADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPV
| .. |||. .. .. |||| .|| |||. |. |. .| || | |.| | ...| | || .|.||| ||.||.... ..|
eaqeagknrykdvgcldnnrvkl...egpwpheyihanyvstptnpkrfictqaplektcadfwymclqdkveaifmlcnllekgakkcleyfaskdkdv
TY-----GSIQVSVQALQQYD-----HWVIREFSI---SQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVReaiqktASDRPIVAHCSAGA
|.| ... .... . ...| . | . || |.||.. ||| ||| ..|... | .| ||| |||||
lefeekgqkisvkfessvtlkfrkdakakvtetvlviegpgekarkvthyhwidwpdrgvpaadlailellekar......pskgpivvhcsagi
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 742-866 | 4.7e-27 | 89.9 | In-house | 21-139 (144) | alignment | ||
Range on Protein: 742-866
Range on HMM: 21-139/144.0
SVQALQQYDHWVIREFSISQGDEIRKLT--QYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktaSDRPIVAHCSAGVGRTGTYIALDRLMqamqENDyID
... |...... . .. . | . . ||....|||||||| . .|.|.. ..||.. ...|.. |||||||||||..|..... ... ..
dlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale...eggpvlVHCsaGvgRtgtlvaaylmk....klg.ls
IFGIICEMRMQRNHMVQTEKQYIFIHE
.. .. ..|..| ..|... |..|..|
leealalvrsrrpgavpnpgqlrfLle
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 540-720 | 6.2e-27 | 89.0 | In-house | 53-232 (305) | alignment | ||
Range on Protein: 540-720
Range on HMM: 53-232/305.0
MVNRAKNRFTNILPYEHSRVKLAalaDDSDTDYINANYIPGYNSP-REFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADY---
.. .|||.... ..| |||. . | .||| |||. | . |...|||| |.|..| |. ..| |||| . || ||.|| .||||
diaitknryqdvpcqdqsavkld...kpspsdyihanyvgcpmipekrficaqgpldqtidefwwmviqnkveqivmlcktvelgklkcaqywpaaqgek
NPVTYGSIQVSVQ---ALQQYDHWVIREFSISQ-GDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVReaiqktASDRPIVAHCSAGA
. | . | ... | . .. ||. . . .. ||| ||| | |... ..| | ||| |||||
lelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair......gskvpivvhcsagi
|
|||||||||
subfamily_CG7180_pd | Subfamily CG7180 | 722-870 | 1e-26 | 88.2 | In-house | 125-288 (296) | alignment | ||
Range on Protein: 722-870
Range on HMM: 125-288/296.0
KCHEYWPADYnPVTYGSIQVSVQALQQYDHWVIREFSISQG------------DEIRKLTQYHFMSWPD-HGVPDKTWTMLDFVRTVREAIQKT---ASD
....||| . || | | . .|| . .||.| . . | | ...... |. . || | ......| || ..|.
mypsywpnks.keqygeifveiveekqyanlkirtfkltkkivalteqekqvkaetRivklfqlteWeledkvPlstnalielrrrvrlwrekvdedpee
RPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
|.| ..| |..|.| |.|.| .. ..... .|.|. . .| .|...|.. ..| .| . . .
gPvvvvssdGasRsGvylaidanlelvekeeevdvFeavktlrrsRpqLvenveeYkyiYdvlle
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 541-720 | 1.4e-26 | 88.2 | In-house | 42-215 (288) | alignment | ||
Range on Protein: 541-720
Range on HMM: 42-215/288.0
VNRAKNRFTNILPYEHSRVKLAalaDDSDTdYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVT-
| ...|..|. . .|||| ||.| ||.|| .. . .| .. .| || ||.. .|.|. |. ||||..|.|||| | ||.| .
anptrdryenlprcditrvkls...ddpdf.yiaanvvssakykrrlicaqaPlngtieelWkmllesdveyivmlcellekGkeksaeyfPsklGekar
YGSIQVSVQ-ALQQYDHW-VIREFSISQGDEIRK-LTQYHFMSWPDHGVPEKTWTMLDFVRTVreaiqkTASDRPIVAHCSAGA
.| . |. .. |. .. . ||. | .. . . |. |.|.||||. . | .. . . ..||| |.|||.
igrlctvvkkkradidklvkvsllriskegeekvivkilhlleWdddgvPenylsplrllevl......kslqkPivvhssaGv
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 577-719 | 1.7e-26 | 88.2 | In-house | 1-99 (152) | alignment | ||
Range on Protein: 577-719
Range on HMM: 1-99/152.0
YIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWpadynpvtygsiqvsvqalqqydhwvirefsisqgdeirkltQYH
.|.||. |.||.|.|||.| |..| |||..| . ..|||||.|.|.||.||..|. ||.
fidgyampfefiatqgpgpntladfwrmlkelgittivmltellelgklkceqyi..........................................qyl
FMSWPDHGVPEKTWTMLDFVRTVREAiqKTASDRPIVAHCSAG
.. |||||||. . .|.... .... . .. |.. |||||
hlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaG
|
|||||||||
subfamily_Sponge-PTP5_pd | Subfamily Sponge-PTP5 | 721-874 | 3.8e-26 | 86.6 | In-house | 115-268 (283) | alignment | ||
Range on Protein: 721-874
Range on HMM: 115-268/283.0
IKCHEYWPADyNPVTYGSIQVSVQALQQYDHWVIREFSISQG---DEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVreAIQKTASDRPIVAHCSAGVG
||| ||| . . || |... . ..|.|. . . . |. | . | . | ... | . . . |. . ||| |||.|.|
ikCsqyWPkr.GsedyGeftvtlrkettsnsfiikelllrvnssakstlllahyqvidWleygeqaiinslvkfnkvi..slqteskkgPivvhCstgiG
RTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRR
||...||. .. .. . .|.| .. || || .||| || ..|| |..
rtavfiaasasvkdaltesvvdvfavvkimreqrmmavqtldqyklvhelvleqalc
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 530-633 | 4.6e-26 | 86.4 | In-house | 37-152 (350) | alignment | ||
Range on Protein: 530-633
Range on HMM: 37-152/350.0
KDQAIVSALEMvnRAKNRFTNILPYEHSRVKLAA--------LADDSDTDYINANYIPGY------NSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVM
| . . .|. ||||..|||||||||||| | |||||||. |. ..| |.||| ||||....| . | .|..
nDvilseGvel..faknrYknilPYehsrvkLkkslkssdakkhslstnDYinanYlkltrfsveinpdfkYiatqaPlpstvddfykvillnkvkvils
LTQLVEKGKIKCHEYWPA
||..|| . ||..||.
ltsdvelnlekcyrYWqe
|
|||||||||
0049260 | (Phosphotyrosine protein) phosphatases II | 721-866 | 5.2e-26 | 86.6 | In-house | 49-144 (152) | alignment | ||
Range on Protein: 721-866
Range on HMM: 49-144/152.0
IKCHEYWpadynpvtygsiqvsvqalqqydhwvirefsisqgdeirkltQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqKTASDRPIVAHCSAGVGRTG
.||..|. ||... |||||||| . .|.... .... . .. |.. ||||||||||
lkceqyi..........................................qylhlpwpDhgvpdlsqlllflllfiekl..aldkggpvlVHCsaGvgRtg
TYIALDRLMqamqenDYIDIFGIICEMRMQRNHMVQTEKQYIFIHE
|..|.. .. .... .. .|..|...|... |..|..|
tlvaaylml......lgvsleeavalvrekRpgavpnpgqlrflye
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 528-723 | 2e-25 | 84.2 | In-house | 37-228 (301) | alignment | ||
Range on Protein: 528-723
Range on HMM: 37-228/301.0
VGKDQaIVSALEMVNRAKNRFTNIlPYEHSRVkLaALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKC
. ||. | .. ... |.|. .. | . | . . .| | ||.|| |. |.| ||||. | .|.| |. . ||||.| ||| . ||
idkdh.itesyaylpkdkhryptv.PckPsta.v.evivdGkrvPihanwiptsGhphrfiatqgPlkntsedfwamlvqydvekivmlgqkvekleekc
HEYWPADY-NPVTYGSIQVSVQALQQY--DHWVIREFSISQG---DEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREaiqktaSDRPIVAHCSAGAI
.|| | . . . | .. .. .. .. . |.. . . | .| | ...|.|.|||. . |.. |.. |..||| |||||
eeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkk......sekPivvhcsaGiG
KC
.
rs
|
|||||||||
subfamily_Cele-PTP-6_pd | Subfamily Cele-PTP-6 | 719-871 | 7.5e-25 | 82.6 | In-house | 120-276 (307) | alignment | ||
Range on Protein: 719-871
Range on HMM: 120-276/307.0
GAIKCHEYWPADY-NPVTYGSIQ--VSVQ-----ALQQYDHW-VIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaiqktaSDRPIV
. |||..|||.. . ..|. .||. | .. . .. . ... | .... . |||.|||. | .... .|| |.|
akikceqywpleegqklvfgeapntisvanlgakklapdedlinvttlkvdwaqksrtiqhlqwenwpdrgvpqinltainlleavry......dtnpvv
AHCSAGVGRTGTYIALDRLMQAM-QENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
||||||||.|| .|. ... | . . |. .. |.| ||.. .||| ||...| ...
vhcsaGvGrsGtivaislvqdkmiaGinckdmkklveelrsqrhyaiqteaqylylhrvlley
|
|||||||||
subfamily_Cele-PTP-18_pd | Subfamily Cele-PTP-18 | 761-874 | 2.2e-24 | 80.7 | In-house | 181-289 (305) | alignment | ||
Range on Protein: 761-874
Range on HMM: 181-289/305.0
QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVReaiqktASDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDI-FGIICEMRMQRNHMVQTEK
| . || |.||.. ||| ||| ..|... | .| ||| |||||.||||. . |. ... . . . |. |. .| ||| .||..
pgekarkvthyhwidwpdrgvpaadlailellekar......pskgpivvhcsagigrtgsvvmleyildqllagqiiedtdkilqkireqrnnsiqtda
QYIFIHECVMDLLRR
||.|.|. ... .|.
qylfvhqvilnyfrk
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 553-719 | 9.6e-24 | 79.4 | In-house | 1-120 (178) | alignment | ||
Range on Protein: 553-719
Range on HMM: 1-120/178.0
PYEHSRVKLAALADDSDTDYINANYIPGYnsprEFMACQGPlpgtvDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNpvtygsiqvsvqalqq
|....||.| | . .|||||..| .. ......| | .....| . . ||.||. .| |..||..||| ...
pldrtrvllsnleglersdyinaseilpg....lylgslpp.....addlellkelgithivnlteelelgflkcdpywpeeag................
ydhwvirefsisqgdeirklTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQktASDRPIVAHCSAG
||... .||||||. .. .|.||. ..||.. ...|.. |||||
....................iqylhipipDhgvpdllehflefvefieeald..ekggpvlVHCsaG
|
|||||||||
0044763 | (Phosphotyrosine protein) phosphatases II | 721-872 | 1.3e-23 | 78.9 | In-house | 64-171 (178) | alignment | ||
Range on Protein: 721-872
Range on HMM: 64-171/178.0
IKCHEYWPADYNpvtygsiqvsvqalqqydhwvirefsisqgdeirklTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQktASDRPIVAHCSAGVGRTG
.||..||| ... ||... .||||||| .. .|.||. ..||.. ...|.. ||||||||.|
lkcdpywpeeag....................................iqylhipipDhgvpdllehflefvefieeald..ekggpvlVHCsaGvgRsg
TYIALDRLMQAmqendYIDIFGIICEMRMQRNhMVQTEKQYIFIHECVMDLL
| .|.. ... .... .| ..|..|. .|... |. ...|. . ||
tlvaaylmkkl.....glsleeaielvrerRp.ivpnpgqlrqLyefelrll
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 513-720 | 2.3e-23 | 77.5 | In-house | 3-203 (267) | alignment | ||
Range on Protein: 513-720
Range on HMM: 3-203/267.0
DSDFRFTEEYDEIRLVGKDQAI-VSALEMVNRAKNRFTNILPYEHSRVKLAaladDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTS
|.. . .|...|. . .... . . |...||. . |||...|| | ... .|||| |. ||. . |.. |.|| |. | . .| ..| .
deeceiekefelikkisdtsstisqsiaeknqernrlddnlpyddtrvilr....tkeeeyinasyvegyktknafivtqdplkntitdfltvihdqkvp
IIVMLTQlVEKGKIKchEYWPAD-YNPVTYGSIQVSVQALQQYDHWVIREFSI-SQGDEIRKLTQYHFMSWPDHgVPEKTWtmLDFVRTVREAIQKTASD
.||.||. | ...|. .|| . | . | .. . . | . . . . ...| |.. | . .| . | . . | .
vivlltk.vftdnir..lfwPPkmgqakkyqdltvehslekeendyqiitlelkfknesahnvtlyyykkwnin.tnnkpy..lkplfgilaknqlengn
RPIVAHCSAGA
||.| .||.|
rPlvvacsdGv
|
|||||||||
subfamily_Choan-PTP-3_pd | Subfamily Choan-PTP-3 | 721-869 | 2.5e-23 | 77.3 | In-house | 120-274 (287) | alignment | ||
Range on Protein: 721-869
Range on HMM: 120-274/287.0
IKCHEYWPADYNPVTYGSIQVSV--QALQQYDhWVIREFSISQ--GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVR---EAIQKTASDRPIVAHCS
||..||| |. | | . . .. . . .| . . . . | | . |....||||.... . .. || |. |. .... |.| |..
lkcykywPerevPmrvGGysvvlldydikePe.ygvralrlidletrearvvkqldllswPdkvlaPtavglirfvldvkqhielardasevGPlvvhdd
AGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVM
.|.||.|...|. |.. ... .|. .. .|..|. .||. |. .. | ..
vGiGrsGillatlvlvsrledlGrvdvaavvirlreyraalvqavvqlrllyealv
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 723-868 | 2.6e-23 | 77.7 | In-house | 49-149 (151) | alignment | ||
Range on Protein: 723-868
Range on HMM: 49-149/151.0
CHEYWPADYnpvtygsiqvsvqalqqydhwvirefsisqgdeiRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaiqktASDRPIVAHCSAGVGRTGTY
|.||.|. ..........|||.|.|. . ..|.|.. ... .. |.. |||||.|||||
cpeylpelg..................................ievlhipildwpdpglplsfdavleflellld.....kkngpvlvHCsaGkgRTGtl
IALDRLMQAmqendyIDIFGIICEMRMQRNHMVQTEKQYIFIHECV
.||..... .... .. |.|..| ..||.. |..|.. ..
valylmllg......vsleealeeyrlkrpgvvqpnqqflfqlfal
|
|||||||||
subfamily_Cele-PTP-20_pd | Subfamily Cele-PTP-20 | 719-871 | 3.1e-23 | 76.9 | In-house | 132-282 (290) | alignment | ||
Range on Protein: 719-871
Range on HMM: 132-282/290.0
GAIKCHEYWPADY-NPVTYGSIQVSVQALQQYDHWV-IREFSISQGDE--IRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAiqktasDRPIVAHCSA
| ||..|.| . .|.|.| | .. | . . .|. . |. || .. .||||. |. | ..| .|..|.| |.| ||||
GkakceqyypekeGevltfGeitvlcseeddkdaniikktlsvrdkdsGkehklkhlkikswpdksvalstlallrtlrilrka......sGpvvvhcsa
GVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
|.|||||..|.. .| . . .|. ... .| | || . ||. . | ..||
GiGrtGtfvaievglqilldGkeldlldlvralrnsrlnsvqvdiqylalveilldl
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 542-720 | 3.2e-22 | 73.5 | In-house | 52-234 (310) | alignment | ||
Range on Protein: 542-720
Range on HMM: 52-234/310.0
NRAKNRFTNILPYEHSRVKLAaLADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTYG
. |||..... . ||||| . ||| |||. |. .|||| |. |.||||..... |..| . .|.|. || |||. |||
ymhknrysdvvcldtsrvklk.idksryedyihanyvktnylrstficsqgplqhtiidfwrmifqeraesilllckvgeegrpkcvgywpslgvtetyg
SIQVSVQAlQQYDHWVIREFSIS----------QGDEIRKL--TQYHFMSWPDHGVPEKTwtmldfVRTVREAIQKTASDRPIVAHCSAGA
|.|. . . . . | ..... | ....| . .. ||| |||.. . || . . | | |||||
cirvtnls.esseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdek......chtvpqrllaqvrhgpcvvhcsagk
|
|||||||||
subfamily_Sponge-PTP9_pd | Subfamily Sponge-PTP9 | 722-872 | 4.1e-22 | 73.2 | In-house | 126-293 (301) | alignment | ||
Range on Protein: 722-872
Range on HMM: 126-293/301.0
KCHEYWPA-DYNPVTYGSIQVSVQALQQYDHWVIREFS-----------------ISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKTa
||..||| . . ..| ..| .. | | .|||... ... . ....|.. .||..|| |.| . | . ||
kceqywpnseaeseefgpftvtlvneqvyPdfvirqlnvkiqdgsnngyierkfkvksdksswdvlqlqvtdWpqdGvvreprtvLqviddvihrqqki.
SDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
. |.| |||..|.|.|.|.... . . . .|.|... .| .. .|.| .||..|.. . |
gggpvvVHCSdtVsrsGvYcsvsiglEQckaegVVdvfqvtkavrrskpgaVtTLeqytsiydvidmyl
|
|||||||||
0051082 | (Phosphotyrosine protein) phosphatases II | 570-720 | 3.7e-21 | 70.7 | In-house | 3-103 (151) | alignment | ||
Range on Protein: 570-720
Range on HMM: 3-103/151.0
TDYINANYIPGYnspreFMACQGPLPgtvdDMWRMIWEKKTSIIVMLTQLVEKGkiKCHEYWPADYnpvtygsiqvsvqalqqydhwvirefsisqgdei
.||||..|. |. . ...|||. | .....| . . ||.|....| | .|.||.|.
sdyinfsyvtgg.....lyrsggpla....dflellkelgiktivnlrseeerg..ycpeylpelg..................................
RKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREaiqktASDRPIVAHCSAGA
..........|||.|.|. . ..|.|.. ... .. |.. |||||
ievlhipildwpdpglplsfdavleflellld.....kkngpvlvHCsaGk
|
|||||||||
0049772 | (Phosphotyrosine protein) phosphatases II | 766-874 | 7.4e-21 | 70.6 | In-house | 178-282 (314) | alignment | ||
Range on Protein: 766-874
Range on HMM: 178-282/314.0
RKLTQYHFMSWPDHGVPdKTWTMLDFVRTVREAiqktASDRPIVAHCSAGVGRTGTYIALDRLMQAMQendyIDIFGIICEMRMQRN-----HMVQTEKQ
| .|. . .||...| . ...|.. ..|| ..|.. ||.||.|||||..... || ... ... .. ..|..| ..... .|
rlgikylripvpDgsap.lledfdeflefieea....dkggpvlvHCkaGkgRtgtfvvaaylmkllg....vsleealedvrlkRpinpnpgfieqleq
YIFIHECVMDLLRR
|.||.|.....|..
yefilealleylkf
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 744-873 | 2.1e-20 | 67.7 | In-house | 155-277 (312) | alignment | ||
Range on Protein: 744-873
Range on HMM: 155-277/312.0
QALQQYDHWVIREFSISQGDEiRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVReaiqKtaSDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGI
.. .. | |.. . |.| || .| . ||||||.|| | | .. .|. | .|..|||||||||||| . .. .. |.. .. .
kskdkithrvlkvvvkatgqe.sklnhyqwaswpdhgmpdscdtalrllsavk....k..dkkpviahcsagvgrtgtlaliesmiaalrhprkqnvkds
ICEMRMQRNHMVQTEKQYIFIHECVMDLLR
.| .| |.. ||.. ||...|
fvllrkdrarsvrvfpqyvyalrcvlefly
|
|||||||||
subfamily_Cele-PTP-11_pd | Subfamily Cele-PTP-11 | 518-720 | 3.9e-20 | 66.8 | In-house | 21-220 (312) | alignment | ||
Range on Protein: 518-720
Range on HMM: 21-220/312.0
FTEEYDEIRLVGKDQAIVSALEMvnRAKNRFTNILPYEHSRVKLAAladDsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLT
.| || . . | . | . . ||. || .. | || | . || ||.. | |...|||| |. .|.. .. |..|.
ltkeykavgnivsdsectaflkf..kdlnrypniqcwdrgrftlag...d.enfyihanfvkictkperfvctqgplentcthfwqlalslgstsiillc
QLVEKGKIKCHEYWPADYNPVT----------YGSIQVSVQALQQYDHWVIREFSISQGDEiRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVReaiqKta
.|| | || .| | |.. .. .. | |.. . |.| || .| . ||||||.|. | | .. .|. |
gfvedgsekcakyisdivgfvdledhrvyteycteieiggkskdkithrvlkvvvkatgqe.sklnhyqwaswpdhgmpdscdtalrllsavk....k..
SDRPIVAHCSAGA
.|..||||||
dkkpviahcsagv
|
|||||||||
subfamily_Sponge-PTP1_pd | Subfamily Sponge-PTP1 | 794-870 | 6.6e-20 | 66.2 | In-house | 181-257 (267) | alignment | ||
Range on Protein: 794-870
Range on HMM: 181-257/267.0
TVREAIQKTASDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
. | .||.| .||.||||.||.. .| .. ..... ||| . ..| || .|.| .||.||| . .
gilaknqlengnrPlvvacsdGvGrsGtflvidsqleraktegvsdifdflrkirsqriglvdtkeryiyihellae
|
|||||||||
subfamily_Cele-PTP-10_pd | Subfamily Cele-PTP-10 | 719-870 | 7.6e-20 | 65.7 | In-house | 134-287 (305) | alignment | ||
Range on Protein: 719-870
Range on HMM: 134-287/305.0
GAIKCHEYWPADY---NPVTYGSIQVSVQ---ALQQYDHWVIREFSISQ-GDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVReaiqktASDRPIVAH
| .|| .|||| . | . | ... | . .. ||. . . .. ||| ||| | |... ..| | ||| |
gklkcaqywpaaqgeklelksgivvenvsgskpmerdaeiqitllnltysgdqkmsvrhlqwtewpdrgvppckltslellsair......gskvpivvh
CSAGVGRTGTYIALDRLMQAMQENDYID-IFGIICEMRMQRNHMVQTEKQYIFIHECVMD
||||.||||| .|.. ... . || . .. .| || . .|.. ||.||| ...
csagigrtgtivaieyilekiaenkpcppmpelvkalrdqrafsiqndvqylfihrvmln
|
|||||||||
subfamily_Cele-PTP-8_pd | Subfamily Cele-PTP-8 | 763-872 | 8.7e-20 | 65.9 | In-house | 168-271 (288) | alignment | ||
Range on Protein: 763-872
Range on HMM: 168-271/288.0
DEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVreaiqkTASDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYI
.| . . |. |.|.|||.. . | .. . . ..||| |.||||||||| | ..... .|.. | .. ..| .| . .|||.||.
eekvivkilhlleWdddgvPenylsplrllevl......kslqkPivvhssaGvGrtgtlililialeslrlddflgirsllaklreerfkaiqtemqyl
FIHECVMDLL
..| ||.. |
yvhrcvleel
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 530-649 | 5e-19 | 62.8 | In-house | 38-167 (349) | alignment | ||
Range on Protein: 530-649
Range on HMM: 38-167/349.0
KDQAIVSALEMVnrAKNRFTNILPYEHSRVKLAAL------ADDSD--------TDYINANYI--PGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSII
.| . . .|. ||||. .||||||||||| .. | |||||||. . .. . ..| | ||| |||| ...| .. ..
ddvilseGvelf..aknrykdilPyehsrvklkkslksskvikastsesdsgklddyinanylkltrisvekkyiatqaPlPstvddfykvillngvklv
VMLTQLVEKGKIKCHEYWpadyNPVTYGSIQVSVQA
. |.. |.. ||. || . .| .|.| .|
lsLnddkelslekcdiyw....qelsysnitvklqn
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 541-732 | 1.1e-18 | 62.2 | In-house | 34-226 (285) | alignment | ||
Range on Protein: 541-732
Range on HMM: 34-226/285.0
VNRAKNRFTNILPYEHSRVKLaalaDDSDTDYINANYI--PGYNSpREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP-
| ||.... | .|| | . | ||| |... || . ... ||||| |. |.|.||...| . ..|| |.| | || |.|
anpdlnryadvrcieetrvvl....knhdrdyihaswmrmpgkdq.styittqgplpetlsdfwhmiyqekiayvlmlctlfeggvekcalyypeklgev
VTYGSIQVSVQALQQY--DHWVIREFSISQGDEIRK----LTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKtasDRPIVAHCSAGAIKCHEYWPADY
| .| .... .. .. ... . .. . . . |||. || . |... . |.. | ..||. ||||| . . ||
vkfgkyeitlteckeeaiagtilnaltvintedasseplymnhvqvpwwpdqlapedarpmielykwvkkvnpk...ekpicvhcsagvgrtatfvgidy
N
a
|
|||||||||
subfamily_egg_pd | Subfamily egg | 533-653 | 1.2e-18 | 61.8 | In-house | 31-152 (307) | alignment | ||
Range on Protein: 533-653
Range on HMM: 31-152/307.0
AIVSALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKgkIKCHEYWP
.. |.. |. | | . . ||||| |.| ||.. | ||. .| || ||||.|||..... ||||| .| .|. |||
slttaasdnnlekarskrvhckdssrvklelrrGqylddfihanrvkGkpllnefilaqaplkntvddfwrmvfqeevqyivmltsrkes..erceyywp
A-DYNPVTY--GSIQVSVQALQQY
. ... . ||... ...
kaesdslvtvpGslrienlkvdsk
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 541-717 | 1.4e-17 | 58.2 | In-house | 46-219 (303) | alignment | ||
Range on Protein: 541-717
Range on HMM: 46-219/303.0
VNRAKNRFTNILPYEHSRVKLaaladdSDTDYINANYIPgYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTY
| ||||.... .||.||| ||. || |.|. .| . . | ||. | |.|.|| |.| ...| | |. . .| . . . .
knmdknrfvdvicldhskvkl......sdssyihasyle.ldsskkailtqlplshtaadfwqmiieqkvkcvlllltdseydklggdsvfprnqdflkf
GSIQVSVQALQQ---YDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEK-TWTMLDFVRTVREAIQKTASDRPIVAHCS
. | ... | ||.. |.|.|| | .|. .|| .| . . .. . .. ..| . .| |
eersirvgefkrvelgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymsl
|
|||||||||
subfamily_Cele-PTP-13_pd | Subfamily Cele-PTP-13 | 722-871 | 2e-17 | 57.8 | In-house | 122-268 (281) | alignment | ||
Range on Protein: 722-871
Range on HMM: 122-268/281.0
KCHEYWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVReaiqktASDRPIVAHCSAGVGRTG
|| ||.| . . . . || . | . .| | | .|.. . ||| ||. . || .| .| | | | ||||||||.|
kcaeyfprnahcclqfdklsvsyedstvnkslvttrlnlsyegetrlithwlwkewpdwqvpessevmlkilrkir......arstppvihcsagvgrsg
TYIALDRLMQAMQEN-DYIDIFGIICEMRM-QRNHMVQTEKQYIFIHECVMDL
| .|.. .|... || |. .|. | ||| .||..| . ..|.
tlmaveialqsihshftlpdikqivshlrvtgraasvqtlqqymliwkvlldf
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 771-869 | 6.6e-17 | 55.9 | In-house | 193-285 (302) | alignment | ||
Range on Protein: 771-869
Range on HMM: 193-285/302.0
YHFMSWPDHGVPDKTWTMLDFVRTVrEAIQKTasdrpIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVM
.| .||||| |... | || .. |. .|. .. ||||||||||| .|. .| .... |. |.. .| | ||.|.| |.. ||
lafsawpdhGapkeaytaldilkfc.esykkn.....vlvhcsaGvGrtGtlvaikyGiqlcskkkvtdllsivlpvrqcryGavqdeqqliylllcvt
|
|||||||||
subfamily_Cele-PTP-15_pd | Subfamily Cele-PTP-15 | 774-872 | 1.6e-16 | 55.1 | In-house | 175-270 (285) | alignment | ||
Range on Protein: 774-872
Range on HMM: 175-270/285.0
MSWPDHGVPDKTWTMLDFVRTVREAIQKtasDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL
|||. |. . |... . |.. | ..||. ||||||||| |.. .| . || |... |. ||| | . ||. |..|.. .|. .
pwwpdqlapedarpmielykwvkkvnpk...ekpicvhcsagvgrtatfvgidyatirimenpniemldivremramrfqavqshmqflflyvvlmeyf
|
|||||||||
subfamily_Cele-PTP-19_pd | Subfamily Cele-PTP-19 | 723-865 | 1.9e-16 | 54.7 | In-house | 132-274 (301) | alignment | ||
Range on Protein: 723-865
Range on HMM: 132-274/301.0
CHEYWPADY-NPVTYGSIQVSVQALQQY--DHWVIREFSISQG---DEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaiqktaSDRPIVAHCSAGV
|.|| | . . . | .. .. .. .. . |.. . . | .| | ...|.|.||| . |.. |.. |..||| |||||.
ceeylpvkisekldigrfkikiknkelilnkkiskrtlevedstgkfatrtvthyqysewtdrgvPkshaelfdlmelvkk......sekPivvhcsaGi
GRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIH
||. ..|. . | .... . |.. . ..| .| . |||..| ..
Grsvafigteylareveadptieltealkhlrehrwngvqtnsqlywmt
|
|||||||||
subfamily_Fungi-PTP1_pd | Subfamily Fungi-PTP1 | 770-870 | 2.2e-16 | 54.6 | In-house | 219-342 (350) | alignment | ||
Range on Protein: 770-870
Range on HMM: 219-342/350.0
QYHFMSWPDHGV---PDKTWTMLD----FV-RTVREAIQKTASDRPIVAHCSAGVGRTGTYIALDRLMQ------AMQE----NDYI----D-IFGIICE
| .. |.| .. | . ..|. .. . | ..| ||. |||||||||||...|| |.. ... |. | |. |. |
qlqvknWkDlslllnPesilqalevkndliddlfaeshldnarsspilvhCsaGvGrtGtlvtlDsllsdfeilenltkesrkldvaaktrDlisiivne
MRMQRNHMVQTEKQYIFIHECVMD
.| || |||. .|.|||.|...
lrkqrismvqnldqfifiYeallf
|
|||||||||
subfamily_Cele-PTP-14_pd | Subfamily Cele-PTP-14 | 717-884 | 9.2e-16 | 52.3 | In-house | 130-300 (310) | alignment | ||
Range on Protein: 717-884
Range on HMM: 130-300/310.0
SAGAIKCHEYWPADYNPVTYGSIQVSVQAlQQYDHWVIREFSIS----------QGDEIRKL--TQYHFMSWPDHGVPDKTwtmldfVRTVREAIQKTAS
| || |||. ||| |.|. . . . . | ..... | ....| . .. ||| ||||. . || . .
eegrpkcvgywpslgvtetygcirvtnls.esseefeicnlavtfvpdnvpvdeqpanlkelrvslikwpnwpdrgvpdek......chtvpqrllaqvr
DRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMdLLRRGEEeDTGESI
| | |||||..|... .||. .. ... ...|. .. |.. .| .||| ||..|. . .. |||. .. |.|
hgpcvvhcsagkdrlyvvvalklkidkldrglkvdaeevktellksraiciqtelqyliidrvri.ifarget.evaeki
|
|||||||||
subfamily_eak_pd | Subfamily eak | 535-700 | 9.4e-16 | 52.1 | In-house | 47-208 (332) | alignment | ||
Range on Protein: 535-700
Range on HMM: 47-208/332.0
VSALEMVNRakNrFTNILPYEHSRVKLAALADDSDtDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPAD
. || ||| | .|.||.. |.|.. . . |||| . . |... . | .|.|. |.|. ||.| . ||.. | |.| .
tarleavnr..n.vvkivpydrylvrltssqlnrl.GyinaslaefsevGrkyiltGiasedkvfafwqmvleqkspaivqlledvelkleksdkyfpdk
Y-NPVTYGSIQVSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTwTMLDFVRTVR
. . .| ..| . . . | . .|.|.| .. |.. | . .| .| . ....
treelkfGildverkefvkrniletrllelskGnethrvlhykvfGwtettlpkye.dflalrkvmk
|
|||||||||
subfamily_Sponge-PTP-7_pd | Subfamily Sponge-PTP-7 | 809-875 | 3.3e-15 | 50.2 | In-house | 2-68 (69) | alignment | ||
Range on Protein: 809-875
Range on HMM: 2-68/69.0
VAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRG
| |||.| |||||.||. | .. . .||| . || | || | .|||||. ... |. |
vvhcssgtgrtgtfiaimvemarikseklvdifnnvqymrkcrpmmvmneieyifihdalvealklG
|
|||||||||
subfamily_Sponge-PTP7_pd | Subfamily Sponge-PTP7 | 809-875 | 1.6e-14 | 48.0 | In-house | 1-67 (69) | alignment | ||
Range on Protein: 809-875
Range on HMM: 1-67/69.0
VAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRG
| |||.| |||||.||. | .. . .||| . || | || | .|.|||. ... |. |
vvhcssGtGrtGtfiaimvemarikseklvdifnnvqymrkcrpmmvmneneymfihdalvealklG
|
|||||||||
subfamily_Sponge-PTP3_pd | Subfamily Sponge-PTP3 | 496-592 | 1.9e-14 | 47.6 | In-house | 3-95 (95) | alignment | ||
Range on Protein: 496-592
Range on HMM: 3-95/95.0
KPIVLNKFEGHYGRMKADSDFRFTEEYDEIRLVGKDQAIVSALEmVNRAKNRFTNILPYEHSRVKLAAladDSDTDYINANYIPGYNSPREFMACQG
||| . | | |...|| | .|. | . | . | | |||| ||.||. .|| |.. |.||||| .. || ..|.||
kpihvsvfhshvlemhsnsdqefdnefksismtsgapytvgsse.anipknrflnifpydatrvvltt...krdsdyinacfvdgyarkncyiaaqg
|
|||||||||
subfamily_ptpA1_pd | Subfamily ptpA1 | 743-831 | 3.4e-14 | 47.4 | In-house | 162-255 (418) | alignment | ||
Range on Protein: 743-831
Range on HMM: 162-255/418.0
VQALQQYDHW-VIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTV--REAIQKTASDR--PIVAHCSAGVGRTGTYIALDRLMQA
|. .|. .. . |. .. | | .|||.. |||| .||.| . ...... |. .||| ||. |||||||||||. . .|.
veviqdpereiitrnirltfegetrditqyqyegwpdhnipdhtqpfrqllhsitnrqnqiipssdrnvpiivhcsagvgrtgtfctavimmkk
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 584-719 | 1.2e-13 | 45.7 | In-house | 4-145 (199) | alignment | ||
Range on Protein: 584-719
Range on HMM: 4-145/199.0
PREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSI----SQGDEIRKLTQYHFM
| ..|.| || |. |.|.|.|| . |||. . . . |||. |||. |..... ..| . . . |....| |
qrryiatqhplretmadfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqft
SWPDHGVPEKTwTMLDFVRTVREAIQKT--ASDRPIVAHCSAG
|| .. |. . .. || . || .| | |.. ||| |
swkekttpnva.lfvgfvvasrevskkyeqekdapvivhcsdg
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 585-719 | 1.2e-13 | 45.7 | In-house | 4-144 (198) | alignment | ||
Range on Protein: 585-719
Range on HMM: 4-144/198.0
REFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSI----SQGDEIRKLTQYHFMS
| ..|.| || |. |.|.|.|| . |||. . . . |||. |||. |..... ..| . . . |....| | |
rryiatqhplretladfwqmvwetgsghivmvnddqknkeadypfywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqfts
WPDHGVPEKTwTMLDFVRTVREAIQKT--ASDRPIVAHCSAG
| .. |. . .. || . || .| | |.. ||| |
wkekttpnva.lfvgfvvasrevskkyeqekdapvivhcsdg
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 803-868 | 1.9e-13 | 44.8 | In-house | 245-311 (319) | alignment | ||
Range on Protein: 803-868
Range on HMM: 245-311/319.0
ASDRPIVAHCSAGVGRTGTYIALDRLMQAMQEN-DYIDIFGIICEMRMQRNHMVQTEKQYIFIHECV
| |.| ||| ||||||. || | .. ..|. .|| .. .| .| . |.| .|| ||. .
esqGPlvvhcsdGvGrtGlviasdiairsleeskrsvdiPqlvssvrrdrasavltkeqyefiykvl
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 597-720 | 1.1e-12 | 42.6 | In-house | 40-159 (255) | alignment | ||
Range on Protein: 597-720
Range on HMM: 40-159/255.0
TVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNPVTyGSIQVSVQALQQYDHWVIREFSISQ----GDEIRKLTQYHFMSWPDHGVPEKTWTM
||| ....| .||. .|||. . |.|. ||..|.| . . .|.| . . . |.| | . .... |.. |... || . .
tvdkfyqtivqtktevvvmlcdfaeegvekcssyfplekdekl.kladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelarei
LDFVRTVREaiqktaSdRPIVAHCSAGA
| .. ||. | ...| |||.|
lnilkvvrd......s.ksvvvhCstGi
|
|||||||||
0048076 | (Phosphotyrosine protein) phosphatases II | 645-719 | 1.1e-12 | 43.4 | In-house | 20-91 (145) | alignment | ||
Range on Protein: 645-719
Range on HMM: 20-91/145.0
VSVQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKtasDRPIVAHCSAG
.... |...... . .. . .. |. .||....|||||||. . ..|.|.. ..||... ..|.. |||||
ldlellkdlgittvlnltselellerlgiqylylpwpDhgvpdllellleflefieealke...ggpvlVHCsaG
|
|||||||||
subfamily_Anemone-PTP-3_pd | Subfamily Anemone-PTP-3 | 726-865 | 2.3e-12 | 41.5 | In-house | 50-197 (199) | alignment | ||
Range on Protein: 726-865
Range on HMM: 50-197/199.0
YWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSI----SQGDEIRKLTQYHFMSWPDHGVPDKTwTMLDFVRTVREAIQKT--ASDRPIVAHCSAGVGR
|||. |||. |..... ..| . . . |....| | || .. |. . .. || . || .| | |.. ||| | |
ywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftswkekttpnva.lfvgfvvasrevskkyeqekdapvivhcsdgqgf
TGTYIALDRLMQAMQEN--DYIDIFGIICEMRMQRNHMVQTEKQYIFIH
|| ..||| ... .| .|.| . .| | .. . ..| ||.
tgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
subfamily_Nvec-PTP-3_pd | Subfamily Nvec-PTP-3 | 726-865 | 2.3e-12 | 41.5 | In-house | 49-196 (198) | alignment | ||
Range on Protein: 726-865
Range on HMM: 49-196/198.0
YWPADY-NPVTYGSIQVSVQALQQYDHWVIREFSI----SQGDEIRKLTQYHFMSWPDHGVPDKTwTMLDFVRTVREAIQKT--ASDRPIVAHCSAGVGR
|||. |||. |..... ..| . . . |....| | || .. |. . .. || . || .| | |.. ||| | |
ywpttesgtgkygslsvttktittkpdytitaliltnnttappstreishyqftswkekttpnva.lfvgfvvasrevskkyeqekdapvivhcsdgqgf
TGTYIALDRLMQAMQEN--DYIDIFGIICEMRMQRNHMVQTEKQYIFIH
|| ..||| ... .| .|.| . .| | .. . ..| ||.
tgvfvaldigvrsheesktsvvdlfevakrlrqarcgiisslqhynfiy
|
|||||||||
PTPc_DSPc_SM00012 | 672-720 | 2.6e-12 | 42.2 | In-house | 2-50 (105) | alignment | |||
Range on Protein: 672-720
Range on HMM: 2-50/105.0
LTQYHFMSWPDHGVPEKTWTMLDFVRTVREAIQKTASDRPIVAHCSAGA
...||...||||||||.. .|...| |.. .| .| |.| |||||.
vkhyhytgwpdhgvPeesdsilellravkknknksesskpvvVhCsaGv
|
|||||||||
subfamily_Cele-PTP-4_pd | Subfamily Cele-PTP-4 | 771-871 | 3.6e-12 | 40.3 | In-house | 186-284 (302) | alignment | ||
Range on Protein: 771-871
Range on HMM: 186-284/302.0
YHFMSWPDHGVPDKTWTMLDFVRTVreAIQKTASDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
|.. |... ||.| .. . | .|. .| ..| |.|| |. ..| .. .|... | |. .| || ..|.. |||.... ...
yvltnWkqkkvpvkyaeliktaakv..fakkikadentvivSknGaGRagafltlavaveklqkgkepnikeivksiRsqRpravdslkQyvslyialll
L
.
y
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 545-719 | 7.1e-12 | 40.1 | In-house | 22-201 (290) | alignment | ||
Range on Protein: 545-719
Range on HMM: 22-201/290.0
KNRFTNILpYEHSRVKLAALADDSDTDYINANYIPgYNSPREFMACQGPLPG-------TVDDMWRMIWEKKTSIIVMLTQLVEKGKI----KCHEYWPA
..| .. | |..|| | ||| ||.. . . .... | |. |. . | |. . | .||| . || . | .| |
dqRlevpL.veatrvvLkgygkrfnddyiHAnrvt.cpnglrliltqsPqekitekrnStiekfwwmakqEkvkqvVmlcefeeksantslfaCakYvpe
DYN-PVTYGSIQVSVQALQQYDHWVIREFSISQGDEIR-KLTQYHFMSWPDHGVPEKTWTMLDFVRTVReaiqktASDRPIVAHCSAG
. .... ..|. . . | .|| . .|| ..| . . .| . |.|.| |.|. ...|. ||. |.. || |
svgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk......asktpvivHcvdG
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 596-720 | 8.1e-12 | 39.6 | In-house | 45-165 (263) | alignment | ||
Range on Protein: 596-720
Range on HMM: 45-165/263.0
GTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP-VTYGSIQVSVQALQQydHWVIREFSISQ--G--DEIRKLTQYHFMSWPDHGVPEKTW
|.| ....| .||. .|||. |.|. || .|.| . . . ..|.. |. ... . . | .......| . |... ||..
qtidkfyqtivqtktevvvmLcDfneegvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpelar
TMLDFVRTVREaiqktaSdRPIVAHCSAGA
.| .. .|. | ...|.|||.|
eilnilkvarn......s.kslvvhcstGi
|
|||||||||
subfamily_Cele-PTP-1_pd | Subfamily Cele-PTP-1 | 722-871 | 1.6e-11 | 38.9 | In-house | 112-258 (290) | alignment | ||
Range on Protein: 722-871
Range on HMM: 112-258/290.0
KCHEYWPADYN-PVTYGSIQVSVQALQQYDHWVIREFSISQGDEIR-KLTQYHFMSWPDHGVPDKTWTMLDFVRTVReaiqktASDRPIVAHCSAGVGRT
| .| | . .... ..|. . . | .|| . .|| ..| . . .| . |...| |.|. ...|. ||. |.. || |. |
aCakYvpesvgeelkfkgltvkCkskekeddvetRelvvkfddeeeftvtHsllkgWnklnvqedtktllsliqkvk......asktpvivHcvdGiSrs
GTYIALDRLMQAMQ-ENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
. |.. .| . .. . . .. ..| ||.......... |. .. |
AalaaiilgyQkiaetsgsvkledvlkalrkqralaitsalelafvdagivll
|
|||||||||
0048179 | (Phosphotyrosine protein) phosphatases II | 646-719 | 4e-11 | 38.3 | In-house | 21-93 (144) | alignment | ||
Range on Protein: 646-719
Range on HMM: 21-93/144.0
SVQALQQYDHWVIREFSISQGDEIRKLT--QYHFMSWPDHGVPEKTWTMLDFVRTVREAIQktaSDRPIVAHCSAG
... |...... . .. . | . . ||....|||||||. . .|.|.. ..||.. ...|.. |||||
dlellkklgittvinlteeyepefleregiqylhlpwpDhgvpdllellleflefieeale...eggpvlVHCsaG
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 580-648 | 4.3e-11 | 36.8 | In-house | 231-296 (440) | alignment | ||
Range on Protein: 580-648
Range on HMM: 231-296/440.0
GYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKgkiKCHEYWPADYNPVTYGSIQVSVQ
|| |.| | || || |.||.. . . | |.|| || .| | ||| . ||.| . | .
gyskknafiatqmpldstvldfwrlvhdyristiimlnqlndk...tcsiywpvntrsvtfgpftvghk
|
|||||||||
subfamily_Sponge-PTP-4_pd | Subfamily Sponge-PTP-4 | 552-685 | 5.3e-11 | 36.9 | In-house | 3-126 (130) | alignment | ||
Range on Protein: 552-685
Range on HMM: 3-126/130.0
LPYEHSRVKlaaladdsDTDYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQLVEKgkikcHEYWPaDYNPVTYGSIQVSVQALQ
|..| ||.. . .||||... . .|.. | || | |.|.|. |. ..|.| . |. |||| | .|. . .. | .
lefevsrlq........gntyinasfvGllgrtaeylltqhpladtsmdfwkmmleryvnvlvvlgsveee.....deywp.dsePlewyeediivtltd
QYDHWVIREFSISQGDEIRK----LTQYHFMSWPDHGV
. . |. . ... . || .. || |
rdefknikasnleiesdlneshqaltmfqisnwpsdgt
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 804-870 | 5.9e-11 | 36.8 | In-house | 227-293 (297) | alignment | ||
Range on Protein: 804-870
Range on HMM: 227-293/297.0
SDRPIVAHCSAGVGRTGTYIALDRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMD
. ... ||||||||.| . | ... .. . |. |. .| || .||| .|. .... |.
rnayllvhcsaGvGrsGvvvlsdvilaklrkkripdvaailsilreqrarlvqtleqfellydavlk
|
|||||||||
fn3 | Fibronectin type III domain | 18-97 | 1.2e-10 | 34.5 | Pfam-A | 2-81 (85) | alignment | ||
Range on Protein: 18-97
Range on HMM: 2-81/85.0
AVGNISVTQYATTTADVQWNLMQ-CSDCIYNYFLLTFEPDSQEpIRVDYTTGVNEYSYQVSGLTEGRNYNFTVVSVSGVGV
|..|.||.. .|.. ..|. . .. | .| . | ...| . .|. ...|....||..|..|.|.| .|.|.|
aPenlsvsevtstsltlsWsppkdgggpitgYeveyrekggge.ewkeftvprtttsvtltgLkpgteYefrVqavngage
|
|||||||||
subfamily_Fungi-PTP2_pd | Subfamily Fungi-PTP2 | 800-871 | 1.6e-10 | 34.8 | In-house | 260-343 (349) | alignment | ||
Range on Protein: 800-871
Range on HMM: 260-343/349.0
QKTASDRPIVAHCSAGVGRTGTYIALDRLMQ--AMQENDYID----------IFGIICEMRMQRNHMVQTEKQYIFIHECVMDL
.|. ... ||||| ||||... || |.. . .|.. |. |. |.| || ||| .|.|.|.|...
ldtdqlstllvhcsaGcGrtGvlvtldlllsileplqnesnkiklqallkDlisiivnelrkqrismvqnlaqfiaiyealLky
|
|||||||||
subfamily_PTPDC1_pd | Subfamily PTPDC1 | 757-870 | 2.8e-10 | 34.9 | In-house | 71-174 (182) | alignment | ||
Range on Protein: 757-870
Range on HMM: 71-174/182.0
FSISQGDEIRKLTQYHFMSWPDHGVPDKTwTMLDFVRTVREAIQKTasdrPIVAHCSAGVGRTGTYIALDrLMQAMQendyIDIFGIICEMRMQRNHMVQ
|| .. . .. .. ..|.|.||. . ..|| |. | |.|. . || || |||| || |. | . .. | .| .| . .|
fsYdlealmeqgiyvynfgwkDygvasle.riLdivkvvafalqeg....kvavhChaGlGrtGvliacy.lvyakr....ltaekaiklvrskrpksiq
TEKQYIFIHECVMD
| .| ...| .
treqvelvkefalf
|
|||||||||
subfamily_Cele-PTP-9_pd | Subfamily Cele-PTP-9 | 719-880 | 3e-10 | 34.6 | In-house | 66-230 (255) | alignment | ||
Range on Protein: 719-880
Range on HMM: 66-230/255.0
GAIKCHEYWPADYNPVTyGSIQVSVQALQQYDHWVIREFSIS----QGDEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaiqktaSdRPIVAHCSA
| ||..|.| . . .|.| . . . |.| | . . .... |.. |... |. . .| .. ||. | ...| |||.
gvekcssyfplekdekl.kladvnvtttkssadvvlrtleitstlgekkkthtvkhysykGWieknaPelareilnilkvvrd......s.ksvvvhCst
GVGRTGTYIALDRLMQ----AMQEN--DYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLL-RRGEEEDT
|.||. ... . . | .... .| .. |.| .|. ..| | | |.||. .|| |.
GiGrsaafvlaelvyqkmirsldttetveldylslleelrskrkraihtPlqlafsilmvldlvfpkgeleak
|
|||||||||
subfamily_Sponge-PTP-2_pd | Subfamily Sponge-PTP-2 | 540-687 | 3.3e-10 | 33.1 | In-house | 25-156 (169) | alignment | ||
Range on Protein: 540-687
Range on HMM: 25-156/169.0
MVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINAnyipgynsprefmacqgplpgtvddmwRMIWEKKTSIIVMLTQLVEKGKIKCH----EYWPADY
.| .||| . | | |||| . .| .||||| ||||| .|.||.| . .| . . ||
tcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlgdtddknnfwpekedyqlhpavi
NPVTY-GSIQVSVQALQQYDHWVIREFSI-----SQGDEIR-KLTQYHFMSWPDHGVPE
| |. | . ... . | | . | |.. ||. .|. .||. |||.
lgewytdslyvrtdkvhantsgveglfevsmvihsydddvteklsllhystwpqngvpq
|
|||||||||
subfamily_Cele-PTP-12_pd | Subfamily Cele-PTP-12 | 542-627 | 4.3e-10 | 33.6 | In-house | 34-118 (332) | alignment | ||
Range on Protein: 542-627
Range on HMM: 34-118/332.0
NRAKNRFTNILPYEHSRVKLAAlaDDSDTDYINANYIPGYNSPREFMACQGPLPGTVDD-MWRMIWEKKTSIIVMLTQLVEKGKIKC
| || . ..||||.|| .| |. ||... ||. .. .| |. . .|||. |.| |.|... .. || | |.
nmdmnriphlycfdhsrvelap..qdgkddfynaswvdgyskksayifaqapfndhteyvfwrmvserkpsmilvfgdidekqkrka
|
|||||||||
PTEN_1 | 763-852 | 5.4e-10 | 34.4 | In-house | 89-175 (196) | alignment | |||
Range on Protein: 763-852
Range on HMM: 89-175/196.0
DEIRKLTQYHFMSWPDHGVPDKTwTMLDFVRTVREAIQKTASDRPIVAHCSAGVGRTGTyIALDRLMQAMQeNDYIDIFGIICEMRMQRN
..... .|. ....|||.|. ..|... . |.... . . .. || ||.||.|| .. ||.... .. . . ...|.|....
effksgveylhfpieDhgapsls.elfdicksfiewllsdpngnvVlVHCkaGlgRsGt.vvaayLmykgk.ltadeAlelvrekRppga
|
|||||||||
0038934 | (Phosphotyrosine protein) phosphatases II | 769-865 | 8.9e-10 | 34.0 | In-house | 80-170 (194) | alignment | ||
Range on Protein: 769-865
Range on HMM: 80-170/194.0
TQYHFMSWPDHGVPDKTWTMLDFVRTVREAIQKtASDRPIVAHCSAGVGRTGTYIALdrlmqAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFIH
.|. . .||.|.. . ..|.|.. | | ... .. .. || ||.||||| .| .. . .. | .|. |...... ... ..
ieylklpfpddgtvPsleillrfldlvdeflne.dpggvvaVHCkaGlgRtGtlvaa.....YLiyrlgmsaeeAialfrekRpgaipnqdyleall
|
|||||||||
subfamily_Cele-PTP-16_pd | Subfamily Cele-PTP-16 | 747-868 | 1.2e-09 | 32.3 | In-house | 152-275 (303) | alignment | ||
Range on Protein: 747-868
Range on HMM: 152-275/303.0
QQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDK-TWTMLDFVRTVREAIQKTASDRPIVAHCSAGVGRTGTYIALDRL-MQAMQENDYIDIFGII
. | ||.. |.|.|| | .|. .|| .| . . .. . .. ..| . .| | .|.||.||. .. . .|. .|. .
elgdgwvlkvlsvsngdyksflhvhhykawphnsipsdgspkfvkqiwqlqsvlrkysdstptvymslsgcgragtfalfetahlslhseqasldlvkcl
CEMRMQRNHMVQTEKQYIFIHECV
.| | | || |. ... .
envrngrlhavqnlsqfsvvytll
|
|||||||||
subfamily_Sponge-PTP2_pd | Subfamily Sponge-PTP2 | 540-623 | 1.6e-09 | 30.8 | In-house | 24-80 (169) | alignment | ||
Range on Protein: 540-623
Range on HMM: 24-80/169.0
MVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINAnyipgynsprefmacqgplpgtvddmwRMIWEKKTSIIVMLTQLVEKG
.| .||| . | | |||| . .| .||||| ||||| .|.||.| . .|
tcnetknrpagplapshtrvklqrvmedlgsdyina...........................rmiwetnasvivvlGdtddkn
|
|||||||||
subfamily_hpo-7_pd | Subfamily hpo-7 | 719-879 | 1.7e-09 | 32.0 | In-house | 72-234 (263) | alignment | ||
Range on Protein: 719-879
Range on HMM: 72-234/263.0
GAIKCHEYWPADYNP-VTYGSIQVSVQALQQydHWVIREFSISQ--G--DEIRKLTQYHFMSWPDHGVPDKTWTMLDFVRTVREaiqktaSdRPIVAHCS
| || .|.| . . . ..|.. |. ... . . | .......| . |... | .. .| .. .|. | ...|.|||
gvekcssyfPlekdekqklanvnvcttkvqs..dvllktlellstlgeKkkthtvkhysykgWiekndpelareilnilkvarn......s.kslvvhcs
AGVGRTGTYIALDRLMQ----AMQEN--DYIDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRGEEED
.|.||. . . . | .... .| .. |.| .|. ..| | | |.|.. ..
tGiGrsaafsvaElvyqkmirsldttstveldylsLleelrssrkraihtPmqLafsilmvLdfvlnnfakg
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 663-722 | 2.1e-09 | 31.2 | In-house | 82-140 (440) | alignment | ||
Range on Protein: 663-722
Range on HMM: 82-140/440.0
ISQGDEIRKLTQYHFMSWPDHGVPEKTWTMLDFVRTVREAiQKTASDRPIVAHCSAGAIK
.| | | | |||. .|||.|||. . .| ... | |. |. |.. |.. |||||| .
yingiesrtlkqyhyqgwpdkgvpkfagpvlkmiqdvnes.qekagngpllvhcsagagr
|
|||||||||
subfamily_CG42327_pd | Subfamily CG42327 | 694-799 | 4.7e-09 | 30.3 | In-house | 87-194 (319) | alignment | ||
Range on Protein: 694-799
Range on HMM: 87-194/319.0
DFVRTVREaiQKtasDRPIVAHCS---AGAIKCHEYWPAD---YNPVTYGSIQVSVQALQQYDHWVIREFSIS--QGDEIRKLTQYHFmSWPDHGVPDKT
|| ||| | |. | || .. | .| ||.|. | .|| |.|... . |...| . . ...| |.|| | . |.. .|| .
dfwrtvwe..qq...srvivqltdlselGikvcaeylPtketldntslyGdilvtlkgrevkdryaistlllkrvdkeesrelthywy.kwleaevPaee
WTMLDFVRTVREAI
... . ||...
aaliamllevrssl
|
|||||||||
subfamily_Cele-PTP-17_pd | Subfamily Cele-PTP-17 | 563-618 | 5.4e-09 | 30.0 | In-house | 64-118 (347) | alignment | ||
Range on Protein: 563-618
Range on HMM: 64-118/347.0
ALADDSDTdYINANYIPGYNSPREFMACQGPLPGTVDDMWRMIWEKKTSIIVMLTQ
. |||..| |||| .| |. .|.. | ||| || |.|.|. | . .| . .
sraddvet.yinashikfdnaskeyiltqyplpdtvrdfwkmvsvtkvtqvvtife
|
|||||||||
subfamily_Cele-PTP-7_pd | Subfamily Cele-PTP-7 | 595-720 | 7.7e-09 | 29.4 | In-house | 101-232 (302) | alignment | ||
Range on Protein: 595-720
Range on HMM: 101-232/302.0
PGTVDDMWRMIWEKKTSIIVMLTQLVEKGKIKCHEYWPADYNP-VTYGSIQV---SVQ-ALQQY-DHW--VIR--EFSISQGDEIRK--LTQYHFMSWPD
|.. | .| . ...|.| |...||... || ||. . . ...| | ||. |... | .. |. .. . | . .| .|||
kstlekhwalieqynvaivvqlcsfvedeekkcaeyysdkvggelkfgrytvktvsvktdleeftdkksfklytveiknekkkkkvkktvdilafsawpd
HGVPEKTWTMLDFVRTVrEAIQKTasdrpIVAHCSAGA
|| |... | || .. |. .|. .. |||||
hGapkeaytaldilkfc.esykkn.....vlvhcsaGv
|
|||||||||
subfamily_Choan-PTP-4_pd | Subfamily Choan-PTP-4 | 718-786 | 3.5e-08 | 27.6 | In-house | 113-184 (297) | alignment | ||
Range on Protein: 718-786
Range on HMM: 113-184/297.0
AGAIKCHEYWPA-DYNPVTYGSIQVS--VQALQQYDHWVIREFSISQGDEIRKLTQYHFMSWPDHGVPDKTW
| || ||| . . . |.. | . ...|. .. |. . .| |... |.||||||||
dGrdkcapywpsvvqerlkagdvvveflsstsdefdrviltelqliyrsesrvvrhvqflswpdhGvpsdle
|
|||||||||
subfamily_Urchin-PTP-2_pd | Subfamily Urchin-PTP-2 | 536-583 | 4.2e-08 | 27.0 | In-house | 41-88 (440) | alignment | ||
Range on Protein: 536-583
Range on HMM: 41-88/440.0
SALEMVNRAKNRFTNILPYEHSRVKLAALADDSDTDYINANYIPGYNS
| |. |||. ||| |.|||| | . |.||||| || | .|
iaslpnnkvknryrnilaydhsrvmleevkgvpdsdyinasyingies
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subfamily_eak_pd | Subfamily eak | 794-875 | 4.7e-08 | 26.8 | In-house | 226-308 (332) | alignment | ||
Range on Protein: 794-875
Range on HMM: 226-308/332.0
TVREAIQKTASDRPIVaHCSAGVGRTGTYIALDRLMQAM---QENDYiDIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLRRG
|.. | | ||. .. | |.|... .| |.. . ..| | . .| .. .|.| | ...|. ||.| |.| |.|
tlkkyihtppsfapii.qsarGsaraGvfvvidllirlidnkkknly.svedlilkvkskrihsvlvalqhsfiyeivldyllrr
|
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subfamily_PTEN_pd | Subfamily PTEN | 770-864 | 3.6e-07 | 25.3 | In-house | 81-172 (184) | alignment | ||
Range on Protein: 770-864
Range on HMM: 81-172/184.0
QYHFMSWPDHGVPdKTWTMLDFVRTVREAIQKTAsDRPIVAHCSAGVGRTGTYIALdRLMQAMQENDYIDIFGIICEMRMQRNHMVQTEKQYIFI
. . . || | . . ..|..... ... .. .| || || ||||. |. |..... .. .. . |.|.. .. |. | ..
rvavypfdDhnpp.plelleeivediekwleedk.knvvvvHCkaGkGRtGvliva.yllkslllekaeealelfaeaRtknkkgvtiPsqrRYv
|
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subfamily_Sponge-PTP4_pd | Subfamily Sponge-PTP4 | 535-581 | 4.5e-07 | 23.7 | In-house | 32-77 (244) | alignment | ||
Range on Protein: 535-581
Range on HMM: 32-77/244.0
VSALEMVNRAKNRFTNILPYEHSRVKLAAlADDSDTDYINANYIPGY
..|. .| .|||. ||||....|| |.. . .|||||||| |
tnavlsanatknryinilpfdetrvilss.skkegsdyinanyiqgs
|
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subfamily_egg_pd | Subfamily egg | 720-873 | 1.3e-06 | 22.3 | In-house | 120-271 (307) | alignment | ||
Range on Protein: 720-873
Range on HMM: 120-271/307.0
AIKCHEYWP-ADYNPVTY--GSIQVSVQALQQYDH--WVIREFSISQGDEIRKLTQyHFmSWpDHGVPDKTWTMLDFVRTVREAiqktasDRPIVAHCSA
. .|. ||| |. ... . ||... ... . . .. . ||. . . |. . | . .. | .| .|.. .|.| ..
serceyywpkaesdslvtvpGslrienlkvdskadplfrvtklklvGgddeerfle.hw.qg.dvnnssdvysplrvlrklrnl......skpvvvqdil
GVGRTGTYIALDR-LMQAMQENDYI-DIFGIICEMRMQRNHMVQTEKQYIFIHECVMDLLR
|| ...| .|.. |.. .. . . . .|..|. |.. .|.|.. |. ..|
GvskaatlvaieiallsllrGpitkslvlravvflrlrrrlsvesvllylfvyrlvlfffr
|
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fn3 | Fibronectin type III domain | 205-243 | 2.8e-06 | 20.6 | Pfam-A | 1-39 (85) | alignment | ||
Range on Protein: 205-243
Range on HMM: 1-39/85.0
SPVGNPQAEAVDKNTITLTYESPLEPNGDITGYRISYIG
|...|.....| ...||. . | ...|.||||.. |
saPenlsvsevtstsltlsWsppkdgggpitgYeveyre
|